KnockTF-Search

T(co)F Overview

T(co)F:	BCL11A
Species:	Homo sapiens
Knock-Method:	siRNA
T(co)F Class:	C2H2 zinc finger factors
T(co)F Superclass:	Zinc-coordinating DNA-binding domains
Biosample Name:	CD34-derived erythroid progenitors
Tissue Type:	Peripheral_blood
Biosample Type:	Primary cell
# of Control:	6
# of Treat:	6
Data Source:	GEO
Profile ID:	GSE13284
Platform:	GPL570
Pubmed ID:	19056937

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of BCL11A

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Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
TWIST2	BCL11A	6.07083	289.441	47.6773	5.57523	1	0.18136	0.65838	84 AHR	486 AHR	478 AHR
MCOLN3	BCL11A	37.6392	244.062	6.48425	2.69694	2	0.30158	0.74013	52 AP2	274 AML1	305 AML1
TIMP4	BCL11A	9.725	1.59667	0.16418	-2.60664	3	1.95134e-05	0.03468	46 AHRARNT	360 AHR	433 AHR
HRCT1	BCL11A	4.78	28.0617	5.87064	2.55352	4	0.94701	0.99112	36 AP1	267 AML1	329 AML1
NAPSA	BCL11A	13.7133	78.7417	5.74198	2.52155	5	0.31618	0.75097	29 AML1	548 AHR	461 AHR
VWC2	BCL11A	1.75667	9.94833	5.66319	2.50161	6	0.00388	0.27435	70 AHR	430 AHR	579 AHR
EHF	BCL11A	16.2756	91.9167	5.64753	2.49762	7	0.31996	0.7538	59 AP1	429 AHR	532 AHR
IL26	BCL11A	1.78333	8.46333	4.74579	2.24665	8	0.0168	0.37717	23 ARID5A	438 AHRARNT	363 AHRARNT
CELA3B	BCL11A	1.26	5.89833	4.68122	2.22688	9	0.0027	0.2394	52 ALX1	565 AHR	530 AHR
CAV3	BCL11A	1.08333	4.79667	4.42769	2.14655	10	0.00019	0.08991	41 ASCL2	344 AHR	337 AHR
RAX2	BCL11A	6.79333	1.585	0.23332	-2.09964	11	0.0092	0.32912	42 ASCL1	446 AHR	454 AHR
FAM154B	BCL11A	2.92	12.16	4.16438	2.0581	12	0.3574	0.7769	0 NA	0 NA	521 AHR
MOGAT3	BCL11A	138.803	33.525	0.24153	-2.04973	13	0.41106	0.80418	46 AHR	491 AHR	468 AHR
KIF2B	BCL11A	1.25	4.99833	3.99867	1.99952	14	0.05442	0.49189	52 AML1	457 AIRE	569 AHR
TBX22	BCL11A	9.51833	2.71333	0.28506	-1.81064	15	0.00038	0.11316	42 AR	0 NA	296 ALX3

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of BCL11A

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of BCL11A

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T(co)F	Pathway Name	Source	Gene Number
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Target Gene Expression Analysis

Expression Atlas of BCL11A