T(co)F Overview
T(co)F: TCF3
Species: Homo sapiens
Knock-Method: shRNA
T(co)F Class: Basic helix-loop-helix factors (bHLH)
T(co)F Superclass: Basic domains
Biosample Name: MDA-MB468
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 5
# of Treat: 10
Data Source: GEO
Profile ID: GSE38893
Platform: GPL6244
Pubmed ID: 23090119

TCF3- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of TCF3
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of TCF3
Upstream Pathway Annotation of TCF3
T(co)F Pathway Name Source Gene Number
TCF3 p38 signaling mediated by MAPKAP kinases PID 21
TCF3 CDO in myogenesis Reactome 29
TCF3 ID NetPath 38
TCF3 Notch-mediated HES/HEY network PID 48
TCF3 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways 56
TCF3 Notch NetPath 76
TCF3 Regulation of nuclear SMAD2/3 signaling PID 82
TCF3 Wnt NetPath 118
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of TCF3
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines