T(co)F Overview
T(co)F: SPDEF
Species: Homo sapiens
Knock-Method: shRNA
T(co)F Class: Tryptophan cluster factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE40985
Platform: GPL570
Pubmed ID: 23764000

SPDEF- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SPDEF
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SPDEF
Upstream Pathway Annotation of SPDEF
T(co)F Pathway Name Source Gene Number
SPDEF Regulation of Androgen receptor activity PID 54
SPDEF PDGF signaling pathway PANTHER 113
SPDEF AndrogenReceptor NetPath 167
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SPDEF
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines