T(co)F Overview
T(co)F: ETS2
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Tryptophan cluster factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: H441
Tissue Type: Lung
Biosample Type: Cell line
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE43459
Platform: GPL6244
Pubmed ID: 23659968

ETS2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of ETS2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of ETS2
Upstream Pathway Annotation of ETS2
T(co)F Pathway Name Source Gene Number
ETS2 MAPK signaling pathway - fly KEGG 16
ETS2 ERK cascade ( FGF8 signaling (Mouse) ) INOH 17
ETS2 ERK cascade ( FGF8 signaling (Xenopus) ) INOH 17
ETS2 FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) INOH 18
ETS2 FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) INOH 20
ETS2 Dorso-ventral axis formation KEGG 25
ETS2 Oncogene Induced Senescence Reactome 30
ETS2 ID NetPath 38
ETS2 IL2 NetPath 81
ETS2 C-MYB transcription factor network PID 87
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of ETS2
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines