KnockTF-Search

T(co)F Overview

T(co)F:	REST
Species:	Homo sapiens
Knock-Method:	siRNA
T(co)F Class:	C2H2 zinc finger factors
T(co)F Superclass:	Zinc-coordinating DNA-binding domains
Biosample Name:	LNCaP
Tissue Type:	Prostate
Biosample Type:	Cell line
# of Control:	1
# of Treat:	3
Data Source:	GEO
Profile ID:	GSE51461
Platform:	GPL14550
Pubmed ID:	-

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of REST

Showing 1 to 15 of 17,723 entries

Search:

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
LOC730159	REST	23083.3	6.10639	0.00026	-11.8842	1	1.28043e-07	0.00125	0 NA	0 NA	0 NA
PAQR5	REST	43779	17.8571	0.00041	-11.2595	2	0.00034	0.04422	49 REST	370 REST	453 REST
SCHIP1	REST	13948.1	13.3418	0.00096	-10.0299	3	2e-04	0.0352	45 REST	609 REST	661 REST
LOC731779	REST	9491.04	46.8579	0.00494	-7.66213	4	7e-04	0.06629	0 NA	590 REST	490 REST
NKG7	REST	15943.7	96.4066	0.00605	-7.36964	5	2.96727e-05	0.01759	36 ELK1	449 REST	417 REST
CHGA	REST	5.8792	879.305	149.562	7.2246	6	0.00362	0.13579	56 REST	566 REST	546 REST
KCNH6	REST	6.3568	337.525	53.0967	5.73055	7	0.00029	0.04199	65 REST	487 REST	417 REST
SYP	REST	6.10724	268.614	43.9827	5.45886	8	4.76698e-05	0.0185	85 REST	288 REST	428 REST
LRTM2	REST	5.69529	213.71	37.5238	5.22973	9	0.00038	0.04595	55 AP1FJ	474 REST	434 REST
CHRNB2	REST	38.3536	1210.04	31.5495	4.97954	10	0.0026	0.11752	27 REST	387 REST	436 REST
UNC13A	REST	7.41034	223.348	30.1401	4.91361	11	0.00081	0.07176	69 REST	410 REST	457 REST
LOC285419	REST	179.943	6.05107	0.03363	-4.89422	12	6.03845e-06	0.0121	0 NA	664 REST	633 REST
C17orf98	REST	195.696	7.77811	0.03975	-4.65304	13	6.19901e-06	0.0121	30 ARNT	418 REST	453 REST
LOC339788	REST	129.648	5.27017	0.04065	-4.62062	14	2.32567e-06	0.00945	0 NA	116 REST	534 REST
TMC3	REST	116.897	5.396	0.04616	-4.4372	15	2.61666e-06	0.00945	25 ALX4	279 REST	568 REST

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of REST

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of REST

From 1 to 3 results, Total 3 items

Search:

T(co)F	Pathway Name	Source	Gene Number
REST	Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078	WikiPathways	33
REST	HDACs deacetylate histones	Reactome	94
REST	Huntington's disease	KEGG	182

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Target Gene Expression Analysis

Expression Atlas of REST