KnockTF-Search

T(co)F Overview

T(co)F:	CREB1
Species:	Homo sapiens
Knock-Method:	shRNA
T(co)F Class:	Basic leucine zipper factors (bZIP)
T(co)F Superclass:	Basic domains
Biosample Name:	RS4;11
Tissue Type:	Haematopoietic_and_lymphoid_tissue
Biosample Type:	Cell line
# of Control:	1
# of Treat:	2
Data Source:	GEO
Profile ID:	GSE68413
Platform:	GPL10558
Pubmed ID:	26008971

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of CREB1

Showing 1 to 15 of 17,312 entries

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Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
CD163L1	CREB1	58.0929	43.5759	0.75011	-0.41482	1	0.00012	0.99964	13 ELF5	58 BATF	238 AIRE
TNFSF4	CREB1	55.539	41.8635	0.75377	-0.40781	2	0.00013	0.99964	33 AML1	428 CREB1	435 CREB1
ATP9A	CREB1	71.2575	54.5747	0.76588	-0.38481	3	0.00019	0.99964	49 BACH2	583 CREB1	495 CREB1
USP38	CREB1	70.5122	55.9048	0.79284	-0.33489	4	0.00054	0.99964	68 AHRARNT	377 AHRARNT	459 CREB1
NMI	CREB1	62.5367	49.6723	0.79429	-0.33227	5	0.00349	0.99964	30 ASCL2	310 CREB1	388 CREB1
FAM64A	CREB1	83.3962	66.7604	0.80052	-0.32099	6	0.01613	0.99964	0 NA	0 NA	0 NA
MBOAT7	CREB1	56.2047	69.7369	1.24077	0.31123	7	0.00079	0.99964	75 AP1	261 AHRARNT	390 AHR
GABARAP	CREB1	29.1827	36.1574	1.23901	0.30919	8	0.02759	0.99964	76 AHRARNT	441 CREB1	440 CREB1
SCG2	CREB1	64.1306	51.8427	0.8084	-0.30686	9	0.00717	0.99964	47 CREB1	537 CREB1	565 CREB1
CSTB	CREB1	209.591	169.735	0.80984	-0.30429	10	0.21588	0.99964	59 ARNTL	414 CREB1	370 CREB1
PSAT1	CREB1	81.9504	66.7377	0.81436	-0.29625	11	0.00783	0.99964	48 ASCL2	605 CREB1	628 CREB1
TOR3A	CREB1	70.0037	57.0953	0.81561	-0.29405	12	0.011	0.99964	48 AP1	453 AHR	444 AHR
ACAD11	CREB1	519.378	426.109	0.82042	-0.28556	13	0.02612	0.99964	46 AREB6	377 AHR	449 AHR
RFC3	CREB1	62.4119	51.3987	0.82354	-0.28009	14	0.00121	0.99964	15 ATF2	626 CREB1	563 CREB1
PRSSL1	CREB1	58.6911	71.0257	1.21016	0.2752	15	0.01099	0.99964	56 AP2ALPHA	313 AHRARNT	438 CREB1

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of CREB1

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of CREB1

From 1 to 10 results, Total 60 items

Search:

T(co)F	Pathway Name	Source	Gene Number
CREB1	CaMK IV-mediated phosphorylation of CREB	Reactome	5
CREB1	CREB phosphorylation through the activation of CaMKK	Reactome	6
CREB1	CREB phosphorylation	Reactome	7
CREB1	CREB phosphorylation through the activation of Adenylate Cyclase	Reactome	7
CREB1	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	SMPDB	7
CREB1	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin	SMPDB	7
CREB1	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin	SMPDB	7
CREB1	Intracellular Signalling Through Histamine H2 Receptor and Histamine	SMPDB	8
CREB1	AKT phosphorylates targets in the nucleus	Reactome	9
CREB1	Gastrin-CREB signalling pathway via PKC and MAPK	Reactome	9

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Target Gene Expression Analysis

Expression Atlas of CREB1