T(co)F Overview
T(co)F: SOX9
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: High-mobility group (HMG) domain factors
T(co)F Superclass: Other all-alpha-helical DNA-binding domains
Biosample Name: VCaP
Tissue Type: Prostate
Biosample Type: Cell line
# of Control: 2
# of Treat: 4
Data Source: GEO
Profile ID: GSE76441
Platform: GPL570
Pubmed ID: 27043282

SOX9- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SOX9
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SOX9
Upstream Pathway Annotation of SOX9
T(co)F Pathway Name Source Gene Number
SOX9 Hs_Spinal_Cord_Injury_WP2431_87678 WikiPathways 21
SOX9 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways 40
SOX9 Deactivation of the beta-catenin transactivating complex Reactome 42
SOX9 TGF_beta_Receptor NetPath 220
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SOX9
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines