KnockTF-Search

T(co)F Overview

T(co)F:	ERF
Species:	Homo sapiens
Knock-Method:	CRISPRi
T(co)F Class:	Tryptophan cluster factors
T(co)F Superclass:	Helix-turn-helix domains
Biosample Name:	K562
Tissue Type:	Haematopoietic_and_lymphoid_tissue
Biosample Type:	Cell line
# of Control:	2
# of Treat:	2
Data Source:	ENCODE
Profile ID:	ENCSR268DNJ
Platform:	-
Pubmed ID:	22955616

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of ERF

Showing 1 to 15 of 12,476 entries

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Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
MUSTN1	ERF	0.9	0.005	0.00556	-7.49185	1	0.00106	0.06231	44 AP1	433 AHR	416 AHR
COL25A1	ERF	0.01	0.925	92.5	6.53138	2	0.24	0.37469	62 AREB6	640 AHR	649 AHR
LAMA2	ERF	0.355	0.005	0.01408	-6.14975	3	0.47972	0.60884	30 ARID3B	556 AHR	657 ERF
MUC17	ERF	0.255	0.005	0.01961	-5.67243	4	0.47976	0.60884	31 EBF1	334 AML1	208 AHR
PRTG	ERF	0.005	0.24	48	5.58496	5	0.02353	0.09698	72 AP2REP	530 AIRE	480 AIRE
ATP6V1G2	ERF	0.015	0.675	45	5.49185	6	0.00113	0.06231	61 AHRARNT	389 ERF	414 ERF
SULF2	ERF	0.21	0.005	0.02381	-5.39232	7	0.47979	0.60884	53 AP2	637 AHR	545 AHR
ZNF704	ERF	0.19	0.005	0.02632	-5.24793	8	0.01431	0.08127	55 AHR	508 AHR	583 AHR
LAMC2	ERF	0.185	0.005	0.02703	-5.20945	9	0.01444	0.08161	51 AHR	577 AHR	480 AHR
CREB3L3	ERF	2.67	0.08	0.02996	-5.0607	10	0.00079	0.06231	39 AREB6	455 AHR	431 AHR
CHRFAM7A	ERF	0.01	0.305	30.5	4.93074	11	0.05357	0.14495	43 E2F1	439 AHRARNT	483 ERF
GDPD4	ERF	0.45	0.015	0.03333	-4.90689	12	0.01205	0.07643	33 BACH2	538 AHR	425 AHRARNT
ISM2	ERF	0.01	0.29	29	4.85798	13	0.03333	0.11439	35 AR	413 AML1	402 AIRE
DPYSL5	ERF	0.005	0.14	28	4.80735	14	0.0373	0.1198	91 AHR	500 AHR	456 AHR
BOLL	ERF	0.02	0.525	26.25	4.71425	15	0.25506	0.38975	57 AHR	383 AHRARNT	328 AHR

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of ERF

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of ERF

From 1 to 2 results, Total 2 items

Search:

T(co)F	Pathway Name	Source	Gene Number
ERF	Oncogene Induced Senescence	Reactome	30
ERF	PDGF signaling pathway	PANTHER	113

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Target Gene Expression Analysis

Expression Atlas of ERF