T(co)F Overview
T(co)F: NFYA
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Heteromeric CCAAT-binding factors
T(co)F Superclass: Other all-alpha-helical DNA-binding domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR096VPS
Platform: -
Pubmed ID: 22955616

NFYA- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NFYA
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NFYA
Upstream Pathway Annotation of NFYA
T(co)F Pathway Name Source Gene Number
NFYA ATF6-alpha activates chaperone genes Reactome 10
NFYA ATF4 activates genes Reactome 25
NFYA Activation of gene expression by SREBF (SREBP) Reactome 42
NFYA Validated targets of C-MYC transcriptional repression PID 63
NFYA Antigen processing and presentation KEGG 75
NFYA PPARA activates gene expression Reactome 113
NFYA Direct p53 effectors PID 141
NFYA TGF_beta_Receptor NetPath 220
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of NFYA
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines