T(co)F Overview
T(co)F: NR2C2
Species: Homo sapiens
Knock-Method: CRISPRi
T(co)F Class: Nuclear receptors with C4 zinc fingers
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 3
Data Source: ENCODE
Profile ID: ENCSR808HQN
Platform: -
Pubmed ID: 22955616

NR2C2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NR2C2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NR2C2
Upstream Pathway Annotation of NR2C2
T(co)F Pathway Name Source Gene Number
NR2C2 Nuclear Receptor transcription pathway Reactome 51
NR2C2 Regulation of Androgen receptor activity PID 54
NR2C2 AndrogenReceptor NetPath 167
NR2C2 TNFalpha NetPath 274
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of NR2C2
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines