T(co)F Overview
T(co)F: RAD21
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TcoF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 3
Data Source: ENCODE
Profile ID: ENCSR051NHG
Platform: -
Pubmed ID: 22955616

RAD21- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of RAD21
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of RAD21
Upstream Pathway Annotation of RAD21
T(co)F Pathway Name Source Gene Number
RAD21 Cohesin Loading onto Chromatin Reactome 10
RAD21 Establishment of Sister Chromatid Cohesion Reactome 11
RAD21 Cell cycle - yeast KEGG 66
RAD21 Meiotic synapsis Reactome 76
RAD21 SUMOylation of DNA damage response and repair proteins Reactome 76
RAD21 Resolution of Sister Chromatid Cohesion Reactome 100
RAD21 Cell cycle KEGG 124
RAD21 Separation of Sister Chromatids Reactome 163
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of RAD21
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines