T(co)F Overview
T(co)F: LMNB1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: ENCODE_TF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR656ZOI
Platform: -
Pubmed ID: 22955616

LMNB1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of LMNB1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of LMNB1
Upstream Pathway Annotation of LMNB1
T(co)F Pathway Name Source Gene Number
LMNB1 Initiation of Nuclear Envelope Reformation Reactome 13
LMNB1 Depolymerisation of the Nuclear Lamina Reactome 15
LMNB1 Formation of Senescence-Associated Heterochromatin Foci (SAHF) Reactome 17
LMNB1 FAS signaling pathway PANTHER 37
LMNB1 Caspase Cascade in Apoptosis PID 57
LMNB1 Meiotic synapsis Reactome 76
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of LMNB1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines