| T(co)F: | E2F4 |
| Species: | Homo sapiens |
| Knock-Method: | siRNA |
| T(co)F Class: | Fork head / winged helix factors |
| T(co)F Superclass: | Helix-turn-helix domains |
| Biosample Name: | K562 |
| Tissue Type: | Haematopoietic_and_lymphoid_tissue |
| Biosample Type: | Cell line |
| # of Control: | 2 | # of Treat: | 2 |
| Data Source: | ENCODE |
| Profile ID: | ENCSR874ZXG |
| Platform: | - |
| Pubmed ID: | 22955616 |
#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines
| Target Gene | T(co)F | Mean
Expr. of
Control
|
Mean
Expr. of
Treat
|
Fold Change | Log2FC | Rank | P-value | Corrected _P |
Promoter _T(co)F |
SE_T(co)F | TE_T(co)F |
|---|
| T(co)F | Pathway Name | Source | Gene Number |
|---|---|---|---|
| E2F4 | Hs_GPCRs,_Class_B_Secretin-like_WP334_79716 | WikiPathways | 6 |
| E2F4 | Hs_MAPK_Cascade_WP422_72129 | WikiPathways | 10 |
| E2F4 | TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | Reactome | 18 |
| E2F4 | G0 and Early G1 | Reactome | 25 |
| E2F4 | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | Reactome | 32 |
| E2F4 | Cyclin D associated events in G1 | Reactome | 38 |
| E2F4 | Hs_Tryptophan_metabolism_WP465_85055 | WikiPathways | 45 |
| E2F4 | Hs_TGF-beta_Signaling_Pathway_WP366_90028 | WikiPathways | 67 |
| E2F4 | Regulation of retinoblastoma protein | PID | 67 |
| E2F4 | E2F transcription factor network | PID | 77 |
| E2F4 | TGF-beta signaling pathway | KEGG | 82 |
| E2F4 | Regulation of nuclear SMAD2/3 signaling | PID | 82 |
| E2F4 | Cell cycle | KEGG | 124 |
| E2F4 | TGF_beta_Receptor | NetPath | 220 |