KnockTF-Search

T(co)F Overview

T(co)F:	AR
Species:	Homo sapiens
Knock-Method:	siRNA
T(co)F Class:	Nuclear receptors with C4 zinc fingers
T(co)F Superclass:	Zinc-coordinating DNA-binding domains
Biosample Name:	abl cells
Tissue Type:	Prostate
Biosample Type:	Cell line
# of Control:	3
# of Treat:	3
Data Source:	GEO
Profile ID:	GSE11428
Platform:	GPL570
Pubmed ID:	19632176

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of AR

Showing 1 to 15 of 16,242 entries

Search:

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
CRISP2	AR	0.466667	11.3333	24.2857	4.60204	1	0.000286464863182083	0.36490568307106	30 ARNT	333 AR	211 AR
PDE6C	AR	0.333333	5.83333	17.5	4.12928	2	0.000270534251433398	0.36490568307106	37 AP1	359 AR	414 AR
DEFB114	AR	2.16667	0.133333	0.0615385	-4.02237	3	0.0294810921122147	0.999852161656754	28 BARX2	190 AR	214 AR
TFPT	AR	27.8333	2.13333	0.0766467	-3.70563	4	9.66566839932058e-05	0.362483436285434	45 AP2	0 NA	394 AHR
GJA1	AR	0.6	7.1	11.8333	3.56479	5	0.000131598484821021	0.362483436285434	50 AP1	681 AR	614 AR
DGKI	AR	0.833333	8.73333	10.48	3.38957	6	0.000230441921932523	0.362483436285434	74 AHRARNT	651 AR	643 AR
ANKRD30A	AR	0.666667	6.63333	9.95	3.3147	7	0.0120422345463545	0.917340654754429	29 E2F6	600 AR	606 AR
SYT14	AR	4.93333	0.5	0.101351	-3.30256	8	0.00226064815715053	0.646126889140154	53 AHRARNT	456 AR	532 AR
NRTN	AR	4.86667	0.533333	0.109589	-3.18983	9	0.00129740623019965	0.52028392435136	44 AHRARNT	438 AR	356 AR
SOST	AR	0.7	6.1	8.71429	3.12338	10	6.97972733115383e-05	0.362483436285434	65 AML1	367 AHR	424 AHR
HTN3	AR	4.8	0.566667	0.118056	-3.08246	11	0.0150569579455042	0.963296987874352	31 ALX1	0 NA	195 AR
CELA2B	AR	1.06667	8.66667	8.125	3.02237	12	0.00245269797733589	0.65571820616307	30 AP4	487 AR	438 AHR
ZNF876P	AR	0.433333	3.33333	7.69231	2.94342	13	0.0103875170026331	0.917340654754429	27 ASCL1	179 AIRE	245 AR
CCDC83	AR	8.16667	1.06667	0.130612	-2.93664	14	0.000616522130461366	0.470574591144287	24 ATF2	500 AR	484 AHR
ST8SIA1	AR	0.9	6.8	7.55556	2.91754	15	0.000313040491609984	0.376605102545233	64 AHR	416 AR	504 AR

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of AR

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of AR

From 1 to 10 results, Total 21 items

Search:

T(co)F	Pathway Name	Source	Gene Number
AR	Hs_Androgen_receptor_signaling_pathway_WP138_79958	WikiPathways	27
AR	Hs_DNA_Damage_Response_WP707_82937	WikiPathways	28
AR	Hs_miRNA_Regulation_of_DNA_Damage_Response_WP1530_84694	WikiPathways	28
AR	Nongenotropic Androgen signaling	PID	31
AR	Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078	WikiPathways	33
AR	FOXA1 transcription factor network	PID	45
AR	Notch-mediated HES/HEY network	PID	48
AR	Nuclear Receptor transcription pathway	Reactome	51
AR	Regulation of Androgen receptor activity	PID	54
AR	Coregulation of Androgen receptor activity	PID	61

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Target Gene Expression Analysis

Expression Atlas of AR