KnockTF-Search

T(co)F Overview

T(co)F:	MCM2
Species:	Homo sapiens
Knock-Method:	siRNA
T(co)F Class:	UNKNOW
T(co)F Superclass:	UNKNOW
Biosample Name:	MCF7
Tissue Type:	Mammary_gland
Biosample Type:	Cell line
# of Control:	3
# of Treat:	1
Data Source:	GEO
Profile ID:	GSE31912
Platform:	GPL570
Pubmed ID:	22536322

MCM2- Target Gene Network

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of MCM2

Showing 1 to 15 of 16,242 entries

Search:

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
FGF13	MCM2	6.01003	4.5584	0.365609	-1.45163	1	0.264897004673197	0.999925560383539	110 AHR	329 AHR	616 AHR
IFI6	MCM2	9.09245	7.74566	0.393167	-1.34679	2	0.0224488440830993	0.999925560383539	40 ASCL2	560 AHR	473 AHR
NR1D2	MCM2	6.6901	5.42855	0.417095	-1.26155	3	0.0163550232518344	0.999925560383539	57 ASCL2	339 AML1	416 AML1
NELL2	MCM2	9.93035	8.76027	0.444396	-1.17008	4	0.0671688301780512	0.999925560383539	22 ESRRA	487 AHRARNT	612 AHR
CLIC3	MCM2	5.83778	4.70583	0.4563	-1.13195	5	0.104448578435011	0.999925560383539	51 AP2	453 AHR	455 AHR
AGR3	MCM2	6.87473	5.8009	0.475058	-1.07383	6	0.508787386421848	0.999925560383539	23 AREB6	509 AIRE	535 AHR
C6orf141	MCM2	7.33811	6.27225	0.477689	-1.06586	7	0.0597190352802139	0.999925560383539	38 COUP	289 AHR	296 AHR
ASCL1	MCM2	6.04903	5.0606	0.504024	-0.988435	8	0.17483218414202	0.999925560383539	84 AHR	519 AHR	462 AHR
AKR1C3	MCM2	6.55773	5.57877	0.507346	-0.978959	9	0.15697964912242	0.999925560383539	25 DLX1	365 AIRE	362 AIRE
CYP1A1	MCM2	6.82451	7.80266	1.96994	0.978148	10	0.000574254028411792	0.999925560383539	65 AHR	490 AHR	446 AHR
SLC39A7	MCM2	7.36325	6.39777	0.51211	-0.965476	11	0.070519592562146	0.999925560383539	97 AHRARNT	359 AHR	435 AHR
BAX	MCM2	7.91264	6.95189	0.513788	-0.960756	12	0.18300416656807	0.999925560383539	70 AHRARNT	379 AHR	425 AHR
RAI14	MCM2	5.78958	6.74591	1.94036	0.956326	13	0.00584345511534034	0.999925560383539	59 AP2	645 AHR	631 AHR
ZBTB41	MCM2	7.3371	6.38252	0.515993	-0.954578	14	0.0214207661327242	0.999925560383539	76 AHR	187 AIRE	351 AHR
APOD	MCM2	11.1301	12.0732	1.92273	0.943155	15	0.124274855330937	0.999925560383539	25 ASCL2	416 AHRARNT	393 AHRARNT

Show entries

#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of MCM2

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of MCM2

Showing results 0 to 0, Total_ 0 _items

Search:

T(co)F	Pathway Name	Source	Gene Number
The data in the table is empty

Show entries

<
>

Target Gene Expression Analysis

Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression

Expression Atlas of MCM2

T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)

T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines