KnockTF-Search

T(co)F Overview

T(co)F:	SNAI2
Species:	Homo sapiens
Knock-Method:	shRNA
T(co)F Class:	C2H2 zinc finger factors
T(co)F Superclass:	Zinc-coordinating DNA-binding domains
Biosample Name:	pancreatic cancer stem cells
Tissue Type:	Pancreas
Biosample Type:	Cell line
# of Control:	2
# of Treat:	2
Data Source:	GEO
Profile ID:	GSE155107
Platform:	GPL20844
Pubmed ID:	34628696

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of SNAI2

Showing 1 to 15 of 17,989 entries

Search:

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
FAM50B	SNAI2	36.2897	3101.11	85.4544	6.41708	4	2.240447e-01	0.6510154	51 AP4	544 SNAI2	467 SNAI2
TRIM64	SNAI2	11.1527	813.158	72.9114	6.18807	5	2.028559e-01	0.6510154	28 ARNT	25 EBF1	176 AIRE
OR13G1	SNAI2	16.0369	695.034	43.3397	5.43762	12	1.313269e-01	0.6510154	8 FOXJ2	104 ARID3A	162 ASCL2
MUC12	SNAI2	14.4022	381.76	26.5071	4.7283	24	1.172167e-01	0.6510154	29 ATF5	194 SNAI2	254 SNAI2
GAGE7	SNAI2	19.8985	497.527	25.0032	4.64404	28	2.462851e-01	0.6510154	21 FOXJ2	24 CDX2	98 AREB6
HEMK1	SNAI2	11.9647	297.15	24.8355	4.63433	31	6.028500e-04	0.5311185	57 AHR	580 SNAI2	511 AHR
OR56B1	SNAI2	10.0928	247.683	24.5406	4.6171	32	4.364041e-04	0.5311185	27 AP4	98 SNAI2	242 SNAI2
LRGUK	SNAI2	13.0875	302.117	23.0844	4.52885	38	1.848881e-01	0.6510154	48 CART1	585 SNAI2	548 SNAI2
CLEC3A	SNAI2	9.74598	220.732	22.6485	4.50134	42	1.980237e-01	0.6510154	31 CDC5	541 SNAI2	434 SNAI2
DDTL	SNAI2	9.86455	210.243	21.313	4.41366	46	8.436678e-02	0.6510154	29 CTCF	313 SNAI2	439 SNAI2
GRIA1	SNAI2	18.4042	389.368	21.1565	4.40303	47	2.203927e-01	0.6510154	73 ALX3	450 SNAI2	615 SNAI2
ABCA6	SNAI2	567.998	27.133	0.0477695	-4.38777	49	2.921891e-01	0.6510154	38 ALX1	357 AHRARNT	368 SNAI2
NHLH1	SNAI2	10.3476	213.028	20.5871	4.36367	52	1.987557e-01	0.6510154	74 AP4	510 SNAI2	466 SNAI2
STAB1	SNAI2	11.9395	243.341	20.3813	4.34917	54	2.001805e-01	0.6510154	39 AP2	409 SNAI2	443 SNAI2
COL6A4P2	SNAI2	18.1493	315.567	17.3873	4.11996	72	3.853845e-03	0.5311185	18 ER	183 ARID5A	313 ALX1

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of SNAI2

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of SNAI2

From 1 to 6 results, Total 6 items

Search:

T(co)F	Pathway Name	Source	Gene Number
SNAI2	Hs_miR-509-3p_alteration_of_YAP1-ECM_axis_WP3967_91491	WikiPathways	14
SNAI2	Hs_Kit_receptor_signaling_pathway_WP304_78799	WikiPathways	46
SNAI2	Signaling events mediated by Stem cell factor receptor (c-Kit)	PID	53
SNAI2	Adherens junction	KEGG	70
SNAI2	Regulation of nuclear beta catenin signaling and target gene transcription	PID	80
SNAI2	Direct p53 effectors	PID	141

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Target Gene Expression Analysis

Expression Atlas of SNAI2