T(co)F Overview
T(co)F: RELB
Species: Homo sapiens
Knock-Method: CRISPR
T(co)F Class: Rel homology region (RHR) factors
T(co)F Superclass: Immunoglobulin fold
Biosample Name: SW480
Tissue Type: Colon
Biosample Type: Cell line
# of Control: 4
# of Treat: 4
Data Source: GEO
Profile ID: GSE197576
Platform: GPL18573
Pubmed ID: 35487218

RELB- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of RELB
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of RELB
Upstream Pathway Annotation of RELB
T(co)F Pathway Name Source Gene Number
RELB Alternative NF-kappaB pathway PID 6
RELB CD209 (DC-SIGN) signaling Reactome 21
RELB TSLP NetPath 24
RELB Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016 WikiPathways 26
RELB Hs_TNF_related_weak_inducer_of_apoptosis_(TWEAK)_Signaling_Pathway_WP2036_89910 WikiPathways 27
RELB TWEAK NetPath 35
RELB NIK-->noncanonical NF-kB signaling Reactome 58
RELB Dectin-1 mediated noncanonical NF-kB signaling Reactome 61
RELB IL12-mediated signaling events PID 62
RELB RANKL NetPath 84
RELB Apoptosis signaling pathway PANTHER 104
RELB Inflammation mediated by chemokine and cytokine signaling pathway PANTHER 189
RELB MAPK signaling pathway KEGG 264
RELB TNFalpha NetPath 274
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of RELB
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines