| T(co)F: | SMAD5 |
| Species: | Homo sapiens |
| Knock-Method: | CRISPR |
| T(co)F Class: | SMAD/NF-1 DNA-binding domain factors |
| T(co)F Superclass: | beta-Hairpin exposed by an alpha/beta-scaffold |
| Biosample Name: | K562 |
| Tissue Type: | Haematopoietic_and_lymphoid_tissue |
| Biosample Type: | Cell line |
| # of Control: | 2 | # of Treat: | 2 |
| Data Source: | ENCODE |
| Profile ID: | ENCSR649MBU |
| Platform: | - |
| Pubmed ID: | 22955616 |
#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines
| Target Gene | T(co)F | Mean
Expr. of
Control
|
Mean
Expr. of
Treat
|
Fold Change | Log2FC | Rank | P-value | Corrected _P |
Promoter _T(co)F |
SE_T(co)F | TE_T(co)F |
|---|
| T(co)F | Pathway Name | Source | Gene Number |
|---|---|---|---|
| SMAD5 | Gene expression of smad7 by R-smad:smad4 ( TGF-beta_super_family_signaling_pathway(canonical) ) | INOH | 7 |
| SMAD5 | Hs_Steroid_Biosynthesis_WP496_69016 | WikiPathways | 8 |
| SMAD5 | Gene expression of smad6/7 by R-smad:smad4 ( TGF-beta_super_family_signaling_pathway(canonical) ) | INOH | 8 |
| SMAD5 | ALK2 signaling events | PID | 11 |
| SMAD5 | Negative regulation of (transcription by R-smad:smad4) in TGF beta super family signaling pathway ( TGF-beta_super_family_signaling_pathway(canonical) ) | INOH | 21 |
| SMAD5 | Signaling by BMP | Reactome | 23 |
| SMAD5 | ALK1 signaling events | PID | 26 |
| SMAD5 | BMP signaling pathway ( TGF-beta_BMP Diagram(MolecularVariation) ) | INOH | 34 |
| SMAD5 | BMP receptor signaling | PID | 42 |
| SMAD5 | TGF-beta_super_family_signaling_pathway(canonical) ( TGF-beta_BMP Diagram(MolecularVariation) ) | INOH | 51 |
| SMAD5 | TGF-beta signaling pathway | KEGG | 82 |
| SMAD5 | TGF-beta signaling pathway | PANTHER | 88 |
| SMAD5 | Wnt signaling pathway | PANTHER | 250 |