T(co)F Overview
T(co)F: XRCC5
Species: Homo sapiens
Knock-Method: CRISPR
T(co)F Class: Others
T(co)F Superclass: ENCODE_TF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR276GMG
Platform: -
Pubmed ID: 22955616

XRCC5- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of XRCC5
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of XRCC5
Upstream Pathway Annotation of XRCC5
T(co)F Pathway Name Source Gene Number
XRCC5 2-LTR circle formation Reactome 7
XRCC5 IRF3-mediated induction of type I IFN Reactome 13
XRCC5 DNA-PK pathway in nonhomologous end joining PID 13
XRCC5 Cytosolic sensors of pathogen-associated DNA Reactome 22
XRCC5 BARD1 signaling events PID 29
XRCC5 Coregulation of Androgen receptor activity PID 61
XRCC5 Nonhomologous End-Joining (NHEJ) Reactome 69
XRCC5 Regulation of Telomerase PID 70
XRCC5 AndrogenReceptor NetPath 167
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of XRCC5
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines