T(co)F Overview
T(co)F: SMAD4
Species: Homo sapiens
Knock-Method: CRISPR
T(co)F Class: SMAD/NF-1 DNA-binding domain factors
T(co)F Superclass: beta-Hairpin exposed by an alpha/beta-scaffold
Biosample Name: HepG2
Tissue Type: Liver
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR700FWD
Platform: -
Pubmed ID: 22955616

SMAD4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SMAD4
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SMAD4
Upstream Pathway Annotation of SMAD4
T(co)F Pathway Name Source Gene Number
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SMAD4
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines