KnockTF-Search

T(co)F Overview

T(co)F:	CNOT7
Species:	Homo sapiens
Knock-Method:	shRNA
T(co)F Class:	CCR4-NOT
T(co)F Superclass:	Chromatin Remodeling Factors
Biosample Name:	K562
Tissue Type:	Haematopoietic_and_lymphoid_tissue
Biosample Type:	Cell line
# of Control:	2
# of Treat:	2
Data Source:	ENCODE
Profile ID:	ENCSR113PYX
Platform:	-
Pubmed ID:	22955616

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of CNOT7

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Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
DYDC2	CNOT7	0.01	1.615	161.5	7.33539	1	0.000149094038461077	0.0320010022551457	45 AP2REP	415 AHRARNT	334 AIRE
SEPT4	CNOT7	0.005	0.365	73	6.18982	2	0.00525856733618812	0.0649458281468534	43 AP4	471 AHR	447 AHR
PGLYRP4	CNOT7	0.03	1.565	52.1667	5.70506	3	0.000358932347176199	0.0370497129649969	35 BARHL1	316 AHRARNT	378 AHRARNT
CEBPE	CNOT7	0.01	0.515	51.5	5.6865	4	0.00211491647593965	0.050162828822235	60 AP1	487 AHR	461 AHR
MGAM	CNOT7	0.005	0.245	49	5.61471	5	0.0225519987718382	0.113759145822012	39 ASCL2	370 AHRARNT	434 AHR
TTC39C	CNOT7	0.24	0.005	0.0208333	-5.58496	6	0.26146597841175	0.457179253012049	23 AML1	418 AHRARNT	496 AHRARNT
GPR4	CNOT7	0.005	0.235	47	5.55459	8	0.0578778189097234	0.184930177859465	58 AP4	465 AHR	439 AHR
NHSL1	CNOT7	0.23	0.005	0.0217391	-5.52356	9	0.0230695037048707	0.115104134507164	43 AREB6	535 AHR	511 AHR
GBP3	CNOT7	0.005	0.225	45	5.49185	10	0.0490154977247307	0.169148243792579	25 AIRE	256 AHRARNT	349 AHRARNT
DUOX2	CNOT7	0.01	0.445	44.5	5.47573	11	0.0032051776833013	0.0567969695526302	60 ASCL2	465 AHR	477 AHR
RRAD	CNOT7	0.01	0.44	44	5.45943	12	0.0622708830131195	0.191656807064683	87 AHRARNT	493 AHR	445 AHR
ULK2	CNOT7	0.005	0.185	37	5.20945	15	0.177776476084956	0.35915310328287	70 AP2	288 AHRARNT	399 AIRE
ASZ1	CNOT7	0.005	0.185	37	5.20945	16	0.159196523377215	0.335043522531813	27 AREB6	423 AIRE	439 AIRE
NPY1R	CNOT7	0.06	2.16	36	5.16993	17	0.000120668299440508	0.0320010022551457	44 ARNT	305 AML1	384 AML1
FER1L4	CNOT7	0.01	0.34	34	5.08746	19	0.020592701679764	0.108736562228568	46 ARP1	399 AHR	437 AHR

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of CNOT7

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of CNOT7

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T(co)F	Pathway Name	Source	Gene Number
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Target Gene Expression Analysis

Expression Atlas of CNOT7