T(co)F Overview
T(co)F: Atf4
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Basic leucine zipper factors (bZIP)
T(co)F Superclass: Basic domains
Biosample Name: Quadriceps femoris muscles
Tissue Type: Muscle
Biosample Type: Cell line
# of Control: 8
# of Treat: 8
Data Source: GEO
Profile ID: GSE72658
Platform: GPL6885
Pubmed ID: 26338703

Atf4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Atf4
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Atf4
Upstream Pathway Annotation of Atf4
T(co)F Pathway Name Source Gene Number
Atf4 ARENRF2_PATHWAY BIOCARTA 19
Atf4 FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY WP 317
Atf4 MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS WP 149
Atf4 MAPK_SIGNALING_PATHWAY WP 159
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Atf4
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)