T(co)F Overview
T(co)F: Cbfb
Species: Mus musculus
Knock-Method: knockdown
T(co)F Class: Others
T(co)F Superclass: beta-Scaffold Factors
Biosample Name: Peripheral CD4+CD25hi cells
Tissue Type: Peripheral_blood
Biosample Type: Primary cell
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE18148
Platform: GPL1261
Pubmed ID: 19800266

Cbfb- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Cbfb
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Cbfb

Upstream Pathway Annotation of Cbfb
T(co)F Pathway Name Source Gene Number
Cbfb GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Cbfb GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Cbfb TRANSCRIPTIONAL_REGULATION_BY_RUNX3 REACTOME 78
Cbfb TRANSCRIPTIONAL_REGULATION_BY_RUNX2 REACTOME 63
Cbfb TRANSCRIPTIONAL_REGULATION_BY_RUNX1 REACTOME 198
Cbfb REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY REACTOME 7
Cbfb RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DI REACTOME 87
Cbfb ESR_MEDIATED_SIGNALING REACTOME 160
Cbfb RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN REACTOME 67
Cbfb RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFE REACTOME 35
Cbfb RUNX2_REGULATES_BONE_DEVELOPMENT REACTOME 6
Cbfb REGULATION_OF_RUNX3_EXPRESSION_AND_ACTIVITY REACTOME 54
Cbfb RUNX3_REGULATES_P14_ARF REACTOME 6
Cbfb SIGNALING_BY_NUCLEAR_RECEPTORS REACTOME 210
Cbfb ESTROGEN_DEPENDENT_GENE_EXPRESSION REACTOME 91
Target Gene Expression Analysis
Expression Atlas of Cbfb