T(co)F Overview
T(co)F: Pitx2
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Homeo domain factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: Cornea
Tissue Type: Eye
Biosample Type: Tissue
# of Control: 4
# of Treat: 4
Data Source: GEO
Profile ID: GSE76047
Platform: GPL10787
Pubmed ID: 26968737

Pitx2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Pitx2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Pitx2
Upstream Pathway Annotation of Pitx2
T(co)F Pathway Name Source Gene Number
Pitx2 PITX2_PATHWAY BIOCARTA 15
Pitx2 HEART_DEVELOPMENT WP 46
Pitx2 BMP_SIGNALING_PATHWAY_IN_EYELID_DEVELOPMENT WP 20
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Pitx2
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)