T(co)F Overview
T(co)F: Sox2
Species: Mus musculus
Knock-Method: shRNA
T(co)F Class: High-mobility group (HMG) domain factors
T(co)F Superclass: Other all-alpha-helical DNA-binding domains
Biosample Name: ES cells
Tissue Type: Embryo
Biosample Type: Cell line
# of Control: 1
# of Treat: 1
Data Source: GEO
Profile ID: GSE34170
Platform: GPL6885
Pubmed ID: 23169531

Sox2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Sox2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Sox2
Upstream Pathway Annotation of Sox2
T(co)F Pathway Name Source Gene Number
Sox2 WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY WP 97
Sox2 DOPAMINERGIC_NEUROGENESIS WP 30
Sox2 MIRNAS_AND_TFS_IN_IPS_CELL_GENERATION WP 7
Sox2 MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Sox2
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)