T(co)F Overview
T(co)F: Sox6
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: High-mobility group (HMG) domain factors
T(co)F Superclass: Other all-alpha-helical DNA-binding domains
Biosample Name: Cardiac ventricle
Tissue Type: Heart
Biosample Type: Tissue
# of Control: 15
# of Treat: 15
Data Source: GEO
Profile ID: GSE60958
Platform: GPL6887
Pubmed ID: 27832192

Sox6- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Sox6
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Sox6
Upstream Pathway Annotation of Sox6
T(co)F Pathway Name Source Gene Number
Sox6 SIGNALING_BY_WNT REACTOME 235
Sox6 TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT REACTOME 154
Sox6 DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_C REACTOME 32
Sox6 ENDOCHONDRAL_OSSIFICATION WP 61
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Sox6
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)