T(co)F Overview
T(co)F: Sox9
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: High-mobility group (HMG) domain factors
T(co)F Superclass: Other all-alpha-helical DNA-binding domains
Biosample Name: Trachea
Tissue Type: Lung
Biosample Type: Tissue
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE97788
Platform: GPL6885
Pubmed ID: 27941074

Sox9- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Sox9
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Sox9
Upstream Pathway Annotation of Sox9
T(co)F Pathway Name Source Gene Number
Sox9 SIGNALING_BY_WNT REACTOME 235
Sox9 TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT REACTOME 154
Sox9 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Sox9 DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_C REACTOME 32
Sox9 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Sox9 TRANSCRIPTIONAL_REGULATION_BY_RUNX2 REACTOME 63
Sox9 ENDOCHONDRAL_OSSIFICATION WP 61
Sox9 NEURAL_CREST_DIFFERENTIATION WP 99
Sox9 SPINAL_CORD_INJURY WP 99
Sox9 WNT_SIGNALING_PATHWAY_WP539 WP 108
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Sox9
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)