T(co)F Overview
T(co)F: Stat6
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: STAT domain factors
T(co)F Superclass: Immunoglobulin fold
Biosample Name: Bone marrow-derived macrophages
Tissue Type: Bone_marrow
Biosample Type: Primary cell
# of Control: 12
# of Treat: 12
Data Source: GEO
Profile ID: GSE25088
Platform: GPL1261
Pubmed ID: 21093321 24314139

Stat6- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Stat6
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Stat6
Upstream Pathway Annotation of Stat6
T(co)F Pathway Name Source Gene Number
Stat6 IL4_PATHWAY BIOCARTA 11
Stat6 CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM REACTOME 404
Stat6 INNATE_IMMUNE_SYSTEM REACTOME 1087
Stat6 IMMUNE_SYSTEM REACTOME 1775
Stat6 STING_MEDIATED_INDUCTION_OF_HOST_IMMUNE_RESPONSES REACTOME 7
Stat6 CYTOSOLIC_SENSORS_OF_PATHOGEN_ASSOCIATED_DNA REACTOME 33
Stat6 DOWNSTREAM_SIGNAL_TRANSDUCTION REACTOME 27
Stat6 SIGNALING_BY_PDGF REACTOME 53
Stat6 SIGNALING_BY_INTERLEUKINS REACTOME 270
Stat6 INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING REACTOME 11
Stat6 SIGNALING_BY_RECEPTOR_TYROSINE_KINASES REACTOME 401
Stat6 IL3_SIGNALING_PATHWAY WP 99
Stat6 ADIPOGENESIS_GENES WP 132
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Stat6
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)