T(co)F Overview
T(co)F: Vdr
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Nuclear receptors with C4 zinc fingers
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: Bone marrow-derived macrophages
Tissue Type: Bone_marrow
Biosample Type: Primary cell
# of Control: 4
# of Treat: 4
Data Source: GEO
Profile ID: GSE2421
Platform: GPL339
Pubmed ID: 16118315

Vdr- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Vdr
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Vdr
Upstream Pathway Annotation of Vdr
T(co)F Pathway Name Source Gene Number
Vdr VDR_PATHWAY BIOCARTA 22
Vdr NUCLEARRS_PATHWAY BIOCARTA 32
Vdr METABOLISM REACTOME 1769
Vdr VITAMIN_D_CALCIFEROL_METABOLISM REACTOME 8
Vdr GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Vdr SUMOYLATION REACTOME 165
Vdr NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY REACTOME 48
Vdr METABOLISM_OF_PROTEINS REACTOME 1657
Vdr SUMOYLATION_OF_INTRACELLULAR_RECEPTORS REACTOME 27
Vdr METABOLISM_OF_LIPIDS REACTOME 599
Vdr POST_TRANSLATIONAL_PROTEIN_MODIFICATION REACTOME 1310
Vdr GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Vdr METABOLISM_OF_STEROIDS REACTOME 129
Vdr NUCLEAR_RECEPTORS WP 38
Vdr NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY WP 30
Vdr OVARIAN_INFERTILITY WP 30
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Vdr
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)