| T(co)F: | Brca1 |
| Species: | Mus musculus |
| Knock-Method: | knockout |
| T(co)F Class: | Others |
| T(co)F Superclass: | TcoF-DB_TF |
| Biosample Name: | CD24+ primary mammary epithelial cells |
| Tissue Type: | Mammary_gland |
| Biosample Type: | Cell line |
| # of Control: | 2 | # of Treat: | 2 |
| Data Source: | GEO |
| Profile ID: | GSE67440 |
| Platform: | GPL6885 |
| Pubmed ID: | 26941120 |
#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines
| Target Gene | T(co)F | Mean
Expr. of
Control
|
Mean
Expr. of
Treat
|
Fold Change | Log2FC | Rank | P-value | Corrected _P |
Promoter _T(co)F |
SE_T(co)F | TE_T(co)F |
|---|
| T(co)F | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Brca1 | ATM_PATHWAY | BIOCARTA | 19 |
| Brca1 | G2_PATHWAY | BIOCARTA | 22 |
| Brca1 | ATRBRCA_PATHWAY | BIOCARTA | 19 |
| Brca1 | CELL_CYCLE | REACTOME | 601 |
| Brca1 | GENERIC_TRANSCRIPTION_PATHWAY | REACTOME | 842 |
| Brca1 | SUMOYLATION | REACTOME | 165 |
| Brca1 | SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROT | REACTOME | 74 |
| Brca1 | TRANSCRIPTIONAL_REGULATION_BY_TP53 | REACTOME | 301 |
| Brca1 | METABOLISM_OF_PROTEINS | REACTOME | 1657 |
| Brca1 | REGULATION_OF_TP53_ACTIVITY | REACTOME | 155 |
| Brca1 | HDR_THROUGH_SINGLE_STRAND_ANNEALING_SSA | REACTOME | 35 |
| Brca1 | HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR | REACTOME | 56 |
| Brca1 | DEUBIQUITINATION | REACTOME | 254 |
| Brca1 | METALLOPROTEASE_DUBS | REACTOME | 39 |
| Brca1 | DNA_DOUBLE_STRAND_BREAK_REPAIR | REACTOME | 160 |
| Brca1 | RESOLUTION_OF_D_LOOP_STRUCTURES | REACTOME | 32 |
| Brca1 | HOMOLOGY_DIRECTED_REPAIR | REACTOME | 131 |
| Brca1 | NONHOMOLOGOUS_END_JOINING_NHEJ | REACTOME | 66 |
| Brca1 | HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE | REACTOME | 26 |
| Brca1 | DNA_DOUBLE_STRAND_BREAK_RESPONSE | REACTOME | 76 |
| Brca1 | PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS | REACTOME | 88 |
| Brca1 | POST_TRANSLATIONAL_PROTEIN_MODIFICATION | REACTOME | 1310 |
| Brca1 | REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATIO | REACTOME | 91 |
| Brca1 | G2_M_DNA_DAMAGE_CHECKPOINT | REACTOME | 90 |
| Brca1 | G2_M_CHECKPOINTS | REACTOME | 163 |
| Brca1 | CELL_CYCLE_CHECKPOINTS | REACTOME | 286 |
| Brca1 | DNA_REPAIR | REACTOME | 299 |
| Brca1 | GENE_EXPRESSION_TRANSCRIPTION | REACTOME | 1061 |
| Brca1 | ESTROGEN_SIGNALING | WP | 75 |
| Brca1 | MRNA_PROCESSING | WP | 449 |
| Brca1 | MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY | WP | 290 |