KnockTF-Search

T(co)F Overview

T(co)F:	Dnmt3b
Species:	Mus musculus
Knock-Method:	knockout
T(co)F Class:	Other C4 zinc finger-type factors
T(co)F Superclass:	Zinc-coordinating DNA-binding domains
Biosample Name:	Cardiac ventricle
Tissue Type:	Heart
Biosample Type:	Tissue
# of Control:	10
# of Treat:	10
Data Source:	GEO
Profile ID:	GSE68518
Platform:	GPL6887
Pubmed ID:	26098432

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of Dnmt3b

Showing 1 to 15 of 15,830 entries

Search:

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
Adra1a	Dnmt3b	49.2964	0	51.8958	0.94991	0	7241	2.118574e-01	224 Aebp2	568 Dnmt3b	697 Dnmt3b
Mybphl	Dnmt3b	61.6146	489.03	7.93692	2.98858	1	4.490285e-06	3.850295e-03	137 Arnt2	790 Dnmt3b	743 Dnmt3b
Ptger4	Dnmt3b	0	0	55.1726	53.5154	1	4.399811e-02	13922	351 Adnp	701 Dnmt3b	736 Dnmt3b
Pvalb	Dnmt3b	201.905	55.6904	0.275825	-1.85817	3	1.055799e-01	9.999725e-01	199 Aebp2	686 Dnmt3b	694 Dnmt3b
Myl4	Dnmt3b	257.113	862.473	3.35445	1.74608	4	3.479750e-02	9.999725e-01	383 Dnmt3b	730 Dnmt3b	741 Dnmt3b
Lrtm1	Dnmt3b	3019.99	939.782	0.311187	-1.68415	5	7.798953e-08	1.543273e-04	160 Dnmt3b	725 Dnmt3b	794 Dnmt3b
Psca	Dnmt3b	74.5086	238.358	3.19906	1.67765	6	1.040849e-02	9.635649e-01	80 Aebp2	671 Adnp	704 Dnmt3b
Tnnt1	Dnmt3b	573.624	1600.01	2.78931	1.47991	8	2.632002e-11	2.708243e-07	155 Aff3	599 Dnmt3b	717 Dnmt3b
Aldh1l1	Dnmt3b	61.4973	165.595	2.69272	1.42906	9	3.605175e-16	1.112881e-11	221 Aebp2	777 Dnmt3b	755 Dnmt3b
Nap1l5	Dnmt3b	50.6166	135.902	2.68494	1.42489	10	2.462475e-06	2.452069e-03	219 Dnmt3b	738 Dnmt3b	684 Dnmt3b
Cfd	Dnmt3b	65.9763	162.616	2.46476	1.30145	11	1.789299e-02	9.999725e-01	203 Adnp	768 Dnmt3b	781 Dnmt3b
Sln	Dnmt3b	49.4561	119.219	2.41059	1.26939	13	1.118939e-01	9.999725e-01	72 Ar	703 Dnmt3b	687 Dnmt3b
Alox5	Dnmt3b	85.9387	207.076	2.40957	1.26878	14	3.632819e-11	2.803537e-07	179 Aebp2	571 Dnmt3b	627 Dnmt3b
Slc22a1	Dnmt3b	134.958	317.174	2.35016	1.23276	15	6.816079e-07	8.416222e-04	136 Ahr	765 Dnmt3b	696 Dnmt3b
Krt8	Dnmt3b	64.2387	148.912	2.31811	1.21295	16	3.353305e-07	4.705145e-04	312 Aebp2	803 Dnmt3b	792 Dnmt3b

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of Dnmt3b

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of Dnmt3b

From 1 to 9 results, Total 9 items

Search:

T(co)F	Pathway Name	Source	Gene Number
Dnmt3b	EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	REACTOME	112
Dnmt3b	PRC2_METHYLATES_HISTONES_AND_DNA	REACTOME	81
Dnmt3b	SUMOYLATION	REACTOME	165
Dnmt3b	METABOLISM_OF_PROTEINS	REACTOME	1657
Dnmt3b	POST_TRANSLATIONAL_PROTEIN_MODIFICATION	REACTOME	1310
Dnmt3b	GENE_EXPRESSION_TRANSCRIPTION	REACTOME	1061
Dnmt3b	GLUTATHIONE_AND_ONECARBON_METABOLISM	WP	31
Dnmt3b	ONECARBON_METABOLISM	WP	29
Dnmt3b	MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	WP	290

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Target Gene Expression Analysis

Expression Atlas of Dnmt3b