T(co)F Overview
T(co)F: Ezh2
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TF
Biosample Name: CD8+ T cells
Tissue Type: Lymph
Biosample Type: Primary cell
# of Control: 6
# of Treat: 6
Data Source: GEO
Profile ID: GSE40741
Platform: GPL11180
Pubmed ID: -

Ezh2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Ezh2
Target Gene T(co)F Mean
Expr. of
Control
Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P
Promoter
_T(co)F
SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Ezh2

Upstream Pathway Annotation of Ezh2
T(co)F Pathway Name Source Gene Number
Ezh2 PRC2_PATHWAY BIOCARTA 10
Ezh2 EPIGENETIC_REGULATION_OF_GENE_EXPRESSION REACTOME 112
Ezh2 PRC2_METHYLATES_HISTONES_AND_DNA REACTOME 81
Ezh2 GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Ezh2 OXIDATIVE_STRESS_INDUCED_SENESCENCE REACTOME 38
Ezh2 CELLULAR_SENESCENCE REACTOME 95
Ezh2 PKMTS_METHYLATE_HISTONE_LYSINES REACTOME 67
Ezh2 CHROMATIN_MODIFYING_ENZYMES REACTOME 205
Ezh2 PTEN_REGULATION REACTOME 113
Ezh2 GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Ezh2 REGULATION_OF_PTEN_GENE_TRANSCRIPTION REACTOME 42
Ezh2 TRANSCRIPTIONAL_REGULATION_BY_E2F6 REACTOME 23
Ezh2 CELLULAR_RESPONSES_TO_STIMULI REACTOME 454
Ezh2 INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS REACTOME 260
Ezh2 MECP2_AND_ASSOCIATED_RETT_SYNDROME WP 45
Ezh2 MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Expression Atlas of Ezh2