KnockTF-Search

T(co)F Overview

T(co)F:	Nr4a1
Species:	Mus musculus
Knock-Method:	knockout
T(co)F Class:	Nuclear receptors with C4 zinc fingers
T(co)F Superclass:	Zinc-coordinating DNA-binding domains
Biosample Name:	PyVT mouse mammary tumor cells
Tissue Type:	Mammary_gland
Biosample Type:	Cell line
# of Control:	3
# of Treat:	3
Data Source:	GEO
Profile ID:	GSE131895
Platform:	GPL24247
Pubmed ID:	33087562

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of Nr4a1

Showing 1 to 15 of 9,944 entries

Search:

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
Ednrb	Nr4a1	9.33333	397.333	42.5714	5.41181	2	1.390661e-05	0.0884128	238 Aebp2	670 Nr4a1	639 Aebp2
Fam107a	Nr4a1	235	9.66667	0.0411347	-4.6035	3	1.618537e-04	0.3558840	135 Ar	673 Nr4a1	654 Nr4a1
Fabp4	Nr4a1	67	1178	17.5821	4.13603	4	5.221443e-05	0.1435114	107 Nr4a1	673 Nr4a1	676 Nr4a1
Cyp2f2	Nr4a1	1028	63	0.0612841	-4.02835	6	7.591315e-02	0.7273107	164 Ar	654 Nr4a1	658 Nr4a1
Ogfrl1	Nr4a1	529.333	54	0.102015	-3.29314	8	1.951722e-02	0.7273107	370 Nr4a1	548 Nr4a1	678 Nr4a1
Klk14	Nr4a1	221.667	23	0.103759	-3.26869	9	6.086268e-02	0.7273107	53 Nr4a1	563 Nr4a1	621 Nr4a1
Slc25a48	Nr4a1	1477	213.333	0.144437	-2.79149	11	2.882405e-02	0.7273107	210 Aebp2	725 Nr4a1	626 Nr4a1
Rgs5	Nr4a1	69.6667	478	6.86124	2.77847	12	2.406530e-04	0.3692828	89 Ash2l	438 Nr4a1	490 Nr4a1
Cpm	Nr4a1	2522.33	383.667	0.152108	-2.71683	13	1.872094e-01	0.7316276	319 Nr4a1	796 Nr4a1	747 Nr4a1
Krt6b	Nr4a1	592	92.3333	0.155969	-2.68067	14	2.874290e-02	0.7273107	38 Batf	314 Adnp	381 Adnp
S100a9	Nr4a1	84.3333	14	0.166008	-2.59068	15	7.709511e-02	0.7273107	64 Nr4a1	413 Nr4a1	503 Nr4a1
Rgs4	Nr4a1	111.333	646.333	5.80539	2.53739	16	5.191080e-05	0.1435114	143 Arnt2	607 Nr4a1	620 Nr4a1
Fbn2	Nr4a1	380	66.3333	0.174561	-2.51819	17	1.523865e-01	0.7273107	244 Aebp2	723 Nr4a1	802 Nr4a1
Saa2	Nr4a1	503.333	2797	5.55695	2.47429	18	1.012542e-01	0.7273107	79 Ar	715 Nr4a1	768 Nr4a1
Atp10b	Nr4a1	1358	259	0.190722	-2.39046	19	2.305057e-02	0.7273107	112 Aire	555 Nr4a1	710 Nr4a1

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of Nr4a1

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of Nr4a1

From 1 to 8 results, Total 8 items

Search:

T(co)F	Pathway Name	Source	Gene Number
Nr4a1	AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS	REACTOME	10
Nr4a1	GENERIC_TRANSCRIPTION_PATHWAY	REACTOME	842
Nr4a1	NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	REACTOME	48
Nr4a1	GENE_EXPRESSION_TRANSCRIPTION	REACTOME	1061
Nr4a1	INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS	REACTOME	260
Nr4a1	NUCLEAR_RECEPTORS	WP	38
Nr4a1	SPINAL_CORD_INJURY	WP	99
Nr4a1	MAPK_SIGNALING_PATHWAY	WP	159

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Target Gene Expression Analysis

Expression Atlas of Nr4a1