T(co)F Overview
T(co)F: Kmt2d
Species: Mus musculus
Knock-Method: CRISPR
T(co)F Class: CXXC zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: MA1L
Tissue Type: Liver
Biosample Type: Cell line
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE151225
Platform: GPL17021
Pubmed ID: 32887696

Kmt2d- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Kmt2d
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Kmt2d
Upstream Pathway Annotation of Kmt2d
T(co)F Pathway Name Source Gene Number
Kmt2d SIGNALING_BY_WNT REACTOME 235
Kmt2d TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT REACTOME 154
Kmt2d FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_ REACTOME 23
Kmt2d GENERIC_TRANSCRIPTION_PATHWAY REACTOME 842
Kmt2d PKMTS_METHYLATE_HISTONE_LYSINES REACTOME 67
Kmt2d CHROMATIN_MODIFYING_ENZYMES REACTOME 205
Kmt2d GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Kmt2d TRANSCRIPTIONAL_REGULATION_BY_RUNX1 REACTOME 198
Kmt2d RUNX1_REGULATES_GENES_INVOLVED_IN_MEGAKARYOCYTE_DI REACTOME 87
Kmt2d MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Kmt2d
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)