KnockTF-Search

T(co)F Overview

T(co)F:	Dnmt3b
Species:	Mus musculus
Knock-Method:	siRNA
T(co)F Class:	Other C4 zinc finger-type factors
T(co)F Superclass:	Zinc-coordinating DNA-binding domains
Biosample Name:	embryonic cardiomyocytes
Tissue Type:	Heart
Biosample Type:	Primary cell
# of Control:	3
# of Treat:	3
Data Source:	GEO
Profile ID:	GSE77514
Platform:	GPL19057
Pubmed ID:	27306334

T(co)F

up-regulated gene

down-regulated gene

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:

Target Gene Information of Dnmt3b

Showing 1 to 15 of 16,612 entries

Search:

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F

Target Gene	T(co)F	Mean Expr. of Control	Mean Expr. of Treat	Fold Change	Log2FC	Rank	P-value	Corrected _P	Promoter _T(co)F	SE_T(co)F	TE_T(co)F
I830077J02Rik	Dnmt3b	0.333333	9.66667	29	4.85798	4	6.868065e-04	0.12815744	155 Arntl	587 Dnmt3b	707 Dnmt3b
Rnaset2b	Dnmt3b	14	0.666667	0.047619	-4.39232	6	8.020030e-03	0.28551697	37 Atf3	493 Alx3	507 Aire
H2-Q2	Dnmt3b	100.333	6.33333	0.0631229	-3.98569	10	2.970069e-02	0.50004599	206 Dnmt3b	512 Dnmt3b	618 Dnmt3b
Kremen2	Dnmt3b	0.333333	4.33333	13	3.70044	14	6.312287e-03	0.25135632	222 Aebp2	678 Dnmt3b	732 Dnmt3b
Ly6a	Dnmt3b	81.6667	6.66667	0.0816327	-3.61471	15	1.827146e-03	0.13835186	95 Ar	769 Dnmt3b	688 Dnmt3b
Egfem1	Dnmt3b	0.333333	4	12	3.58496	16	9.943641e-02	0.62127564	161 Dnmt3b	332 Aebp2	751 Dnmt3b
Nlrp12	Dnmt3b	0.333333	4	12	3.58496	18	5.264734e-03	0.22932584	123 Adnp	704 Dnmt3b	667 Dnmt3b
S100a9	Dnmt3b	0.666667	7.66667	11.5	3.52356	23	1.826812e-03	0.13835186	64 Ar	413 Dnmt3b	503 Dnmt3b
Myadml2	Dnmt3b	1.66667	18.6667	11.2	3.48543	24	6.496616e-05	0.08225241	251 Aebp2	690 Dnmt3b	706 Dnmt3b
Pcdha10	Dnmt3b	3.66667	0.333333	0.0909091	-3.45943	25	1.397007e-02	0.37710753	78 Aebp2	457 Dnmt3b	548 Dnmt3b
Vip	Dnmt3b	3.66667	0.333333	0.0909091	-3.45943	26	3.442459e-02	0.52872412	79 Ash2l	306 Ar	540 Dnmt3b
Prss43	Dnmt3b	0.333333	3.66667	11	3.45943	28	2.059027e-02	0.43148328	152 Ascl2	729 Dnmt3b	712 Dnmt3b
Gm3646	Dnmt3b	0.333333	3.66667	11	3.45943	30	2.710729e-03	0.16524214	92 Arnt2	809 Dnmt3b	697 Dnmt3b
C7	Dnmt3b	43.3333	4	0.0923077	-3.43741	34	5.278742e-02	0.55135465	74 Ar	0 Na	569 Dnmt3b
Cd19	Dnmt3b	0.333333	3.33333	10	3.32193	35	3.501090e-03	0.18741730	130 Ascl2	778 Dnmt3b	769 Dnmt3b

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#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.

Function Analysis of Downstream Target Genes of Dnmt3b

Upregulated.Pathways Downregulated.Pathways Global.Plots

Upstream Pathway Annotation of Dnmt3b

From 1 to 9 results, Total 9 items

Search:

T(co)F	Pathway Name	Source	Gene Number
Dnmt3b	EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	REACTOME	112
Dnmt3b	PRC2_METHYLATES_HISTONES_AND_DNA	REACTOME	81
Dnmt3b	SUMOYLATION	REACTOME	165
Dnmt3b	METABOLISM_OF_PROTEINS	REACTOME	1657
Dnmt3b	POST_TRANSLATIONAL_PROTEIN_MODIFICATION	REACTOME	1310
Dnmt3b	GENE_EXPRESSION_TRANSCRIPTION	REACTOME	1061
Dnmt3b	GLUTATHIONE_AND_ONECARBON_METABOLISM	WP	31
Dnmt3b	ONECARBON_METABOLISM	WP	29
Dnmt3b	MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY	WP	290

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Target Gene Expression Analysis

Expression Atlas of Dnmt3b