Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0000393 CDO in myogenesis Reactome Homo sapiens 29 200
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
CTNNA1 ENSG00000044115 1495 Cytoplasm 0.02222222 28.0 0.274819 0.23015873
CTNNA2 ENSG00000066032 1496 Cytoplasm 0.02222222 22.0 0.1088526 0.37662338
MAP2K6 ENSG00000108984 5608 Cytoplasm/Nucleus 0.025 39.0 3.298397 0.13630229
MAPK11 ENSG00000185386 5600 Cytoplasm/Nucleus 0.02702703 42.0 22.90538 0.12311266
MAPK12 ENSG00000188130 6300 Cytoplasm/Nucleus 0.02631579 35.0 13.75464 0.14789916
MEF2D ENSG00000116604 4209 Cytoplasm/Nucleus 0.02173913 19.0 4.244209 0.24561404
MYF5 ENSG00000111049 4617 Cytoplasm/Nucleus 0.01724138 9.0 0.05397727 0.72222222
MYOD1 ENSG00000129152 4654 Cytoplasm/Nucleus 0.02272727 19.0 10.20815 0.20467836
SPAG9 ENSG00000008294 9043 Cytoplasm/Nucleus 0.02564103 20.0 2.971094 0.57894737
BOC ENSG00000144857 91653 Membrane 0.02380952 22.0 13.44111 0.45021645
CDC42 ENSG00000070831 998 Membrane 0.02325581 31.0 8.459276 0.21935484
CDH15 ENSG00000129910 1013 Membrane 0.02173913 17.0 0.03605395 0.55147059
CDH2 ENSG00000170558 1000 Membrane 0.025 25.0 3.4705 0.32666667
CDH4 ENSG00000179242 1002 Membrane 0.02222222 14.0 0.02518439 0.96703297
CDON ENSG00000064309 50937 Membrane 0.02777778 26.0 34.84681 0.35692308
NEO1 ENSG00000067141 4756 Membrane 0.01639344 4.0 0.0 0.5
ABL1 ENSG00000097007 25 Unknown 0.02272727 26.0 0.2195124 0.30769231
BNIP2 ENSG00000140299 663 Unknown 0.02439024 17.0 2.151864 0.75735294
CTNNB1 ENSG00000168036 1499 Unknown 0.02702703 66.0 31.8697 0.05454545
MAPK14 ENSG00000112062 1432 Unknown 0.02702703 49.0 31.39343 0.09013605
MEF2B ENSG00000064489 100271849 Unknown 0.02173913 16.0 4.5035 0.30833333
MEF2A ENSG00000068305 4205 Nucleus 0.02222222 21.0 5.321113 0.24761905
MEF2C ENSG00000081189 4208 Nucleus 0.02173913 27.0 8.096682 0.11965812
MYF6 ENSG00000111046 4618 Nucleus 0.01754386 10.0 0.05397727 0.57777778
MYOG ENSG00000122180 4656 Nucleus 0.02173913 16.0 4.846892 0.25833333
TCF12 ENSG00000140262 6938 Nucleus 0.01818182 16.0 0.9303925 0.325
TCF3 ENSG00000071564 6929 Nucleus 0.02564103 33.0 27.87252 0.14583333
TCF4 ENSG00000196628 6925 Nucleus 0.02173913 18.0 10.14195 0.28104575
NTN3 ENSG00000162068 4917 Secreted 0.01666667 5.0 0.5 0.5
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
CTNNA1 ENSG00000044115 1495 Cytoplasm 1276.0 32500.0 1.56E-6 0.003150778
CTNNA2 ENSG00000066032 1496 Cytoplasm 335.0 2170.0 1.55E-6 0.010528197
MAP2K6 ENSG00000108984 5608 Cytoplasm/Nucleus 2682.0 7380.0 1.56E-6 3.98028E-4
MAPK11 ENSG00000185386 5600 Cytoplasm/Nucleus 3606.0 96400.0 1.56E-6 9.00487E-4
MAPK12 ENSG00000188130 6300 Cytoplasm/Nucleus 1802.0 7750.0 1.56E-6 8.45504E-4
MEF2D ENSG00000116604 4209 Cytoplasm/Nucleus 74.0 477.0 1.55E-6 0.050721955
MYF5 ENSG00000111049 4617 Cytoplasm/Nucleus 23.0 14.5 1.54E-6 0.166007905
MYOD1 ENSG00000129152 4654 Cytoplasm/Nucleus 178.0 10500.0 1.55E-6 0.043864661
SPAG9 ENSG00000008294 9043 Cytoplasm/Nucleus 62.0 372.0 1.55E-6 0.135906928
BOC ENSG00000144857 91653 Membrane 81.0 1520.0 1.55E-6 0.038580247
CDC42 ENSG00000070831 998 Membrane 6876.0 628000.0 1.56E-6 5.19414E-4
CDH15 ENSG00000129910 1013 Membrane 83.0 28.4 1.55E-6 0.107258302
CDH2 ENSG00000170558 1000 Membrane 364.0 2020.0 1.55E-6 0.012411831
CDH4 ENSG00000179242 1002 Membrane 72.0 22.1 1.55E-6 0.135758998
CDON ENSG00000064309 50937 Membrane 86.0 1600.0 1.55E-6 0.036662107
NEO1 ENSG00000067141 4756 Membrane 12.0 34.9 1.53E-6 0.106060606
ABL1 ENSG00000097007 25 Unknown 2172.0 94200.0 1.56E-6 0.002096954
BNIP2 ENSG00000140299 663 Unknown 17.0 1.17 1.55E-6 0.757352941
CTNNB1 ENSG00000168036 1499 Unknown 12389.0 1400000.0 1.57E-6 3.14058E-4
MAPK14 ENSG00000112062 1432 Unknown 9287.0 427000.0 1.56E-6 2.56589E-4
MEF2B ENSG00000064489 100271849 Unknown 24.0 41.8 1.54E-6 0.148550725
MEF2A ENSG00000068305 4205 Nucleus 69.0 1840.0 1.55E-6 0.057544757
MEF2C ENSG00000081189 4208 Nucleus 316.0 28200.0 1.55E-6 0.009222423
MYF6 ENSG00000111046 4618 Nucleus 26.0 29.7 1.55E-6 0.206153846
MYOG ENSG00000122180 4656 Nucleus 46.0 326.0 1.55E-6 0.080193237
TCF12 ENSG00000140262 6938 Nucleus 36.0 20.7 1.54E-6 0.133333333
TCF3 ENSG00000071564 6929 Nucleus 263.0 19400.0 1.56E-6 0.036716687
TCF4 ENSG00000196628 6925 Nucleus 308.0 9160.0 1.56E-6 0.067304032
NTN3 ENSG00000162068 4917 Secreted 51.0 649.0 1.54E-6 0.12
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
CTNNA1 ENSG00000044115 1495 Cytoplasm 113.0 7580.0 3.99E-7 0.033185841
CTNNA2 ENSG00000066032 1496 Cytoplasm 22.0 0.0727 3.99E-7 0.376623377
MAP2K6 ENSG00000108984 5608 Cytoplasm/Nucleus 225.0 7820.0 3.99E-7 0.011111111
MAPK11 ENSG00000185386 5600 Cytoplasm/Nucleus 397.0 41400.0 3.99E-7 0.038635728
MAPK12 ENSG00000188130 6300 Cytoplasm/Nucleus 88.0 2950.0 3.99E-7 0.039968652
MEF2D ENSG00000116604 4209 Cytoplasm/Nucleus 35.0 5900.0 3.99E-7 0.105882353
MYF5 ENSG00000111049 4617 Cytoplasm/Nucleus 9.0 0.0989 3.98E-7 0.722222222
MYOD1 ENSG00000129152 4654 Cytoplasm/Nucleus 19.0 38.6 3.98E-7 0.204678363
SPAG9 ENSG00000008294 9043 Cytoplasm/Nucleus 20.0 326.0 3.99E-7 0.578947368
BOC ENSG00000144857 91653 Membrane 40.0 7630.0 3.99E-7 0.156410256
CDC42 ENSG00000070831 998 Membrane 1354.0 787000.0 4.0E-7 0.007763261
CDH15 ENSG00000129910 1013 Membrane 28.0 96.6 3.99E-7 0.235449735
CDH2 ENSG00000170558 1000 Membrane 39.0 642.0 3.99E-7 0.147098516
CDH4 ENSG00000179242 1002 Membrane 21.0 9.45 3.99E-7 0.452380952
CDON ENSG00000064309 50937 Membrane 42.0 8310.0 3.99E-7 0.152148664
NEO1 ENSG00000067141 4756 Membrane 12.0 24700.0 3.98E-7 0.090909091
ABL1 ENSG00000097007 25 Unknown 204.0 45800.0 3.99E-7 0.02153965
BNIP2 ENSG00000140299 663 Unknown 17.0 429.0 3.99E-7 0.757352941
CTNNB1 ENSG00000168036 1499 Unknown 1677.0 641000.0 4.0E-7 0.003130235
MAPK14 ENSG00000112062 1432 Unknown 531.0 400000.0 4.0E-7 0.02400597
MEF2B ENSG00000064489 100271849 Unknown 16.0 1060.0 3.99E-7 0.308333333
MEF2A ENSG00000068305 4205 Nucleus 32.0 2340.0 3.98E-7 0.106854839
MEF2C ENSG00000081189 4208 Nucleus 57.0 8420.0 3.99E-7 0.043233083
MYF6 ENSG00000111046 4618 Nucleus 10.0 0.0989 3.98E-7 0.577777778
MYOG ENSG00000122180 4656 Nucleus 16.0 305.0 3.98E-7 0.258333333
TCF12 ENSG00000140262 6938 Nucleus 16.0 0.971 3.98E-7 0.325
TCF3 ENSG00000071564 6929 Nucleus 33.0 3190.0 3.99E-7 0.145833333
TCF4 ENSG00000196628 6925 Nucleus 89.0 13900.0 3.99E-7 0.373850868
NTN3 ENSG00000162068 4917 Secreted 5.0 888.0 3.98E-7 0.5
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
ABL1 CDH2 2
ABL1 CDON 3
ABL1 CTNNA1 2
ABL1 CTNNB1 5
ABL1 MAPK14 3
ABL1 SPAG9 2
BNIP2 CDC42 4
BOC CDH15 3
BOC CDH2 3
BOC CDON 3
BOC CTNNB1 5
CDC42 CTNNA1 2
CDC42 CTNNB1 2
CDC42 MAPK11 3
CDC42 MAPK12 2
CDC42 MAPK14 3
CDH15 CDON 2
CDH15 CTNNA1 3
CDH15 CTNNB1 3
CDH2 CDON 3
CDH2 CTNNA1 5
CDH2 CTNNB1 8
CDON CTNNB1 4
CTNNA1 CTNNB1 10
CTNNA2 CTNNB1 4
CTNNB1 SPAG9 2
CTNNB1 TCF3 3
CTNNB1 TCF4 9
MAP2K6 MAPK11 5
MAP2K6 MAPK12 8
MAP2K6 MAPK14 11
MAPK11 MAPK14 3
MAPK11 MEF2A 2
MAPK11 MEF2B 2
MAPK11 MEF2C 4
MAPK11 MEF2D 2
MAPK11 TCF3 2
MAPK12 CTNNB1 1
MAPK12 MEF2A 1
MAPK12 MEF2C 3
MAPK14 MEF2A 6
MAPK14 MEF2B 2
MAPK14 MEF2C 9
MAPK14 MEF2D 4
MAPK14 SPAG9 3
MAPK14 TCF3 2
MEF2A MYOD1 2
MEF2A MYOG 3
MEF2C MYOD1 2
MEF2C MYOG 2
MEF2C TCF3 2
MYF5 TCF3 3
MYF6 TCF12 2
MYF6 TCF3 2
MYOD1 TCF12 2
MYOD1 TCF3 6
MYOD1 TCF4 3
MYOG TCF12 3
MYOG TCF3 4
MYOG TCF4 2
NEO1 NTN3 2
ABL1 BNIP2 1
ABL1 BOC 1
ABL1 CDC42 1
ABL1 CDH15 1
ABL1 CDH4 1
ABL1 CTNNA2 1
ABL1 MAPK11 1
ABL1 MAPK12 1
BNIP2 BOC 1
BNIP2 CDH15 1
BNIP2 CDH2 1
BNIP2 CDH4 1
BNIP2 CDON 1
BNIP2 CTNNA1 1
BNIP2 CTNNA2 1
BNIP2 CTNNB1 1
BNIP2 MAPK11 1
BNIP2 MAPK12 1
BNIP2 MAPK14 1
BNIP2 SPAG9 1
BOC CDC42 1
BOC CDH4 1
BOC CTNNA1 1
BOC CTNNA2 1
BOC MAPK11 1
BOC MAPK12 1
BOC MAPK14 1
BOC NEO1 1
BOC NTN3 1
BOC SPAG9 1
CDC42 CDH15 1
CDC42 CDH4 1
CDC42 CDON 1
CDC42 CTNNA2 1
CDC42 SPAG9 1
CDH15 CTNNA2 2
CDH15 MAPK11 1
CDH15 MAPK12 1
CDH15 MAPK14 1
CDH15 SPAG9 1
CDH2 CDC42 1
CDH2 CDH4 2
CDH2 CTNNA2 2
CDH2 MAPK11 1
CDH2 MAPK12 1
CDH2 MAPK14 1
CDH2 SPAG9 1
CDH4 CDON 1
CDH4 CTNNA1 2
CDH4 CTNNA2 2
CDH4 CTNNB1 2
CDH4 MAPK11 1
CDH4 MAPK12 1
CDH4 MAPK14 1
CDH4 SPAG9 1
CDON CTNNA1 1
CDON CTNNA2 1
CDON MAPK11 1
CDON MAPK12 1
CDON MAPK14 1
CDON NEO1 1
CDON NTN3 1
CDON SPAG9 1
CTNNA1 MAPK11 1
CTNNA1 MAPK12 1
CTNNA1 MAPK14 1
CTNNA1 SPAG9 1
CTNNA2 MAPK11 1
CTNNA2 MAPK12 1
CTNNA2 MAPK14 1
CTNNA2 SPAG9 1
CTNNB1 MAPK11 1
CTNNB1 MAPK14 1
CTNNB1 MEF2B 1
CTNNB1 MYOG 1
MAP2K6 ABL1 1
MAP2K6 BNIP2 1
MAP2K6 BOC 1
MAP2K6 CDC42 1
MAP2K6 CDH15 1
MAP2K6 CDH2 1
MAP2K6 CDH4 1
MAP2K6 CDON 1
MAP2K6 CTNNA1 1
MAP2K6 CTNNA2 1
MAP2K6 CTNNB1 1
MAP2K6 SPAG9 1
MAPK11 SPAG9 1
MAPK12 MEF2B 1
MAPK12 MEF2D 1
MAPK12 SPAG9 1
MEF2A MEF2B 1
MEF2A MEF2C 2
MEF2A MEF2D 3
MEF2A MYF5 1
MEF2A MYF6 1
MEF2A TCF12 1
MEF2A TCF3 1
MEF2A TCF4 1
MEF2B MYF5 1
MEF2B MYF6 1
MEF2B MYOD1 1
MEF2B MYOG 1
MEF2B TCF12 1
MEF2B TCF3 1
MEF2B TCF4 1
MEF2C MEF2D 1
MEF2C MYF5 1
MEF2C MYF6 1
MEF2C TCF12 1
MEF2C TCF4 1
MEF2D MYF5 1
MEF2D MYF6 1
MEF2D MYOD1 1
MEF2D MYOG 1
MEF2D TCF12 1
MEF2D TCF4 1
MYF5 TCF12 1
MYF5 TCF4 1
MYF6 TCF4 1
MYOD1 BNIP2 1
MYOD1 CDH2 1
MYOD1 CDON 1
MYOD1 MYF6 1
MYOD1 SPAG9 1
MYOG CDON 1
MYOG MYF5 1
NTN3 CDC42 1
TCF12 TCF3 4
TCF12 TCF4 2
TCF3 CDH2 1
TCF3 CDON 1
TCF3 MAPK12 1
TCF3 MEF2D 1
TCF3 SPAG9 1
TCF3 TCF4 1
TCF4 MAP2K6 1
Pathway1 Pathway2 Intersect Similarity Scores Pathway Name Source Number of Genes Number of Interactions Detail
pathway0000393 pathway0001569 4 0.5 p38 cascade ( BMP2 signaling(through TAK1) ) INOH 8 24
pathway0000393 pathway0001570 4 0.5 p38 cascade ( TGF-beta signaling(through TAK1) ) INOH 8 24