Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0001181 Interferon gamma signaling Reactome Homo sapiens 88 243
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
CAMK2B ENSG00000058404 816 Cytoplasm 0.00330033 25.0 0.0 0.15
GBP1 ENSG00000117228 2633 Cytoplasm 0.003225807 2.0 0.4016956 0.0
IFI30 ENSG00000216490 10437 Cytoplasm 2.36686E-4 1.0 0.0 0.0
JAK1 ENSG00000162434 3716 Cytoplasm 0.003597122 81.0 150.4464 0.01944444
PRKCD ENSG00000163932 5580 Cytoplasm 0.003584229 24.0 33.77031 0.22101449
PTPN6 ENSG00000111679 5777 Cytoplasm 0.003773585 45.0 282.1009 0.08585859
SOCS1 ENSG00000185338 8651 Cytoplasm 0.003597122 29.0 149.7622 0.04433498
TRIM2 ENSG00000109654 23321 Cytoplasm 0.002785515 1.0 0.0 0.0
TRIM29 ENSG00000137699 23650 Cytoplasm 0.002298851 1.0 0.0 0.0
TRIM5 ENSG00000132256 85363 Cytoplasm 0.003003003 4.0 241.0 0.0
CAMK2D ENSG00000145349 817 Cytoplasm/Nucleus 0.00330033 27.0 0.0 0.12820513
CAMK2G ENSG00000148660 818 Cytoplasm/Nucleus 0.00330033 26.0 0.0 0.13846154
IRF1 ENSG00000125347 3659 Cytoplasm/Nucleus 0.003875969 17.0 317.8582 0.125
IRF4 ENSG00000137265 3662 Cytoplasm/Nucleus 0.002941177 1.0 0.0 0.0
IRF7 ENSG00000185507 3665 Cytoplasm/Nucleus 0.003257329 10.0 91.48984 0.04444444
IRF8 ENSG00000140968 3394 Cytoplasm/Nucleus 0.003412969 7.0 140.2007 0.28571429
IRF9 ENSG00000213928 10379 Cytoplasm/Nucleus 0.003344482 8.0 0.0 0.03571429
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 0.003558719 77.0 90.29379 0.02118934
OASL ENSG00000135114 8638 Cytoplasm/Nucleus 0.002710027 1.0 0.0 0.0
SOCS3 ENSG00000184557 9021 Cytoplasm/Nucleus 0.003389831 37.0 0.0 0.03153153
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 0.003891051 73.0 364.1993 0.0281583
TRIM21 ENSG00000132109 6737 Cytoplasm/Nucleus 0.003584229 9.0 420.4923 0.11111111
TRIM25 ENSG00000121060 7706 Cytoplasm/Nucleus 0.002890173 5.0 4.0 0.1
TRIM35 ENSG00000104228 23087 Cytoplasm/Nucleus 0.002544529 2.0 62.0 0.0
TRIM68 ENSG00000167333 55128 Cytoplasm/Nucleus 2.36686E-4 1.0 0.0 0.0
CD44 ENSG00000026508 960 Membrane 0.002881844 2.0 0.0 0.0
FCGR1A ENSG00000150337 2209 Membrane 0.002949853 2.0 0.0 1.0
HLA-A ENSG00000206503 3105 Membrane 0.003322259 21.0 41.26235 0.10952381
HLA-B ENSG00000234745 3106 Membrane 0.003546099 18.0 80.29509 0.12418301
HLA-C ENSG00000204525 3107 Membrane 0.003289474 18.0 10.99805 0.11111111
HLA-DPA1 ENSG00000231389 3113 Membrane 0.003412969 29.0 21.34697 0.13054187
HLA-DPB1 ENSG00000223865 3115 Membrane 0.003401361 25.0 16.19677 0.15
HLA-DQA1 ENSG00000196735 3117 Membrane 0.003533569 29.0 42.6244 0.12807882
HLA-DQA2 ENSG00000237541 3118 Membrane 0.003355705 27.0 2.98722 0.13960114
HLA-DQB1 ENSG00000179344 3119 Membrane 0.003344482 25.0 0.0 0.15
HLA-DQB2 ENSG00000232629 3120 Membrane 0.003164557 5.0 0.0 1.0
HLA-DRA ENSG00000204287 3122 Membrane 0.003496504 35.0 44.29397 0.09579832
HLA-DRB1 ENSG00000196126 3123 Membrane 0.003703704 31.0 213.7994 0.11397849
HLA-DRB3 NA 3125 Membrane 0.003344482 24.0 0.0 0.16304348
HLA-DRB4 NA 3126 Membrane 0.003344482 24.0 0.0 0.16304348
HLA-DRB5 ENSG00000198502 3127 Membrane 0.003533569 26.0 20.09636 0.15076923
HLA-E ENSG00000204592 3133 Membrane 0.003184713 19.0 17.84427 0.09356725
HLA-F ENSG00000204642 3134 Membrane 0.003378378 17.0 17.36285 0.13235294
HLA-G ENSG00000204632 3135 Membrane 0.00310559 16.0 0.0 0.125
ICAM1 ENSG00000090339 3383 Membrane 0.003076923 2.0 0.0 1.0
IFNGR1 ENSG00000027697 3459 Membrane 0.003546099 59.0 11.99129 0.03623612
IFNGR2 ENSG00000159128 3460 Membrane 0.003546099 49.0 6.703971 0.05272109
PTAFR ENSG00000169403 5724 Membrane 0.002915452 1.0 0.0 0.0
VCAM1 ENSG00000162692 7412 Membrane 0.003194888 3.0 0.0 1.0
HLA-H ENSG00000206341 3136 Unknown 0.002932551 1.0 0.0 0.0
IRF5 ENSG00000128604 3663 Unknown 0.003039514 3.0 11.09877 0.33333333
MID1 ENSG00000101871 4281 Unknown 0.002816901 1.0 0.0 0.0
PML ENSG00000140464 5371 Unknown 0.003194888 3.0 122.0 0.33333333
SP100 ENSG00000067066 6672 Unknown 0.002680965 2.0 62.0 0.0
TRIM34 ENSG00000258659 53840 Unknown 0.002531646 1.0 0.0 0.0
CAMK2A ENSG00000070808 815 Nucleus 0.003508772 33.0 76.61499 0.09469697
CIITA ENSG00000179583 4261 Nucleus 0.003436426 4.0 0.4016956 0.83333333
IRF2 ENSG00000168310 3660 Nucleus 0.003584229 9.0 102.9861 0.25
IRF3 ENSG00000126456 3661 Nucleus 0.003267974 10.0 114.3031 0.06666667
IRF6 ENSG00000117595 3664 Nucleus 0.002857143 2.0 3.358173 0.0
TRIM10 ENSG00000204613 10107 Nucleus 0.002197802 1.0 0.0 0.0
TRIM26 ENSG00000234127 7726 Nucleus 0.002717391 1.0 0.0 0.0
TRIM6 ENSG00000121236 117854 Nucleus 0.002531646 1.0 0.0 0.0
TRIM8 ENSG00000171206 81603 Nucleus 0.003367003 5.0 87.56151 0.2
B2M ENSG00000166710 567 Secreted 0.003584229 19.0 168.1907 0.14035088
IFNG ENSG00000111537 3458 Secreted/Nucleus 0.003787879 63.0 169.6662 0.03891449
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
CAMK2B ENSG00000058404 816 Cytoplasm 2706.0 39900.0 1.56E-6 0.001236111
GBP1 ENSG00000117228 2633 Cytoplasm 3.0 0.0304 1.53E-6 0.0
IFI30 ENSG00000216490 10437 Cytoplasm 2.0 9.35 1.53E-6 0.0
JAK1 ENSG00000162434 3716 Cytoplasm 8612.0 95400.0 1.56E-6 2.70908E-4
PRKCD ENSG00000163932 5580 Cytoplasm 4033.0 210000.0 1.56E-6 0.001307541
PTPN6 ENSG00000111679 5777 Cytoplasm 3244.0 60000.0 1.56E-6 0.001395589
SOCS1 ENSG00000185338 8651 Cytoplasm 1341.0 27000.0 1.56E-6 0.003944483
TRIM2 ENSG00000109654 23321 Cytoplasm 1.0 0.0 1.51E-6 0.0
TRIM29 ENSG00000137699 23650 Cytoplasm 15.0 258.0 1.55E-6 0.323809524
TRIM5 ENSG00000132256 85363 Cytoplasm 4.0 20400.0 1.52E-6 0.0
CAMK2D ENSG00000145349 817 Cytoplasm/Nucleus 2765.0 66200.0 1.56E-6 0.001275767
CAMK2G ENSG00000148660 818 Cytoplasm/Nucleus 2617.0 28900.0 1.56E-6 0.001230195
IRF1 ENSG00000125347 3659 Cytoplasm/Nucleus 243.0 28500.0 1.56E-6 0.029758868
IRF4 ENSG00000137265 3662 Cytoplasm/Nucleus 27.0 6.92 1.54E-6 0.168091168
IRF7 ENSG00000185507 3665 Cytoplasm/Nucleus 775.0 27400.0 1.55E-6 0.001623739
IRF8 ENSG00000140968 3394 Cytoplasm/Nucleus 34.0 12800.0 1.54E-6 0.069518717
IRF9 ENSG00000213928 10379 Cytoplasm/Nucleus 141.0 46.6 1.55E-6 0.010638298
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 9806.0 203000.0 1.56E-6 2.47078E-4
OASL ENSG00000135114 8638 Cytoplasm/Nucleus 2.0 0.0 1.53E-6 0.0
SOCS3 ENSG00000184557 9021 Cytoplasm/Nucleus 2446.0 25700.0 1.56E-6 0.001279164
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 9900.0 278000.0 1.56E-6 2.89632E-4
TRIM21 ENSG00000132109 6737 Cytoplasm/Nucleus 89.0 35700.0 1.55E-6 0.167517875
TRIM25 ENSG00000121060 7706 Cytoplasm/Nucleus 243.0 10700.0 1.55E-6 0.015270551
TRIM35 ENSG00000104228 23087 Cytoplasm/Nucleus 6.0 10600.0 1.53E-6 0.4
TRIM68 ENSG00000167333 55128 Cytoplasm/Nucleus 18.0 8920.0 1.55E-6 0.594771242
CD44 ENSG00000026508 960 Membrane 658.0 66200.0 1.56E-6 0.028470574
FCGR1A ENSG00000150337 2209 Membrane 222.0 4250.0 1.55E-6 0.080061962
HLA-A ENSG00000206503 3105 Membrane 605.0 133000.0 1.56E-6 0.006956379
HLA-B ENSG00000234745 3106 Membrane 409.0 28100.0 1.55E-6 0.006843569
HLA-C ENSG00000204525 3107 Membrane 417.0 17100.0 1.55E-6 0.005464859
HLA-DPA1 ENSG00000231389 3113 Membrane 1157.0 14000.0 1.55E-6 0.002633287
HLA-DPB1 ENSG00000223865 3115 Membrane 1079.0 10000.0 1.55E-6 0.002783791
HLA-DQA1 ENSG00000196735 3117 Membrane 1139.0 13700.0 1.55E-6 0.002695609
HLA-DQA2 ENSG00000237541 3118 Membrane 1135.0 8830.0 1.55E-6 0.002671142
HLA-DQB1 ENSG00000179344 3119 Membrane 1105.0 8910.0 1.55E-6 0.002637878
HLA-DQB2 ENSG00000232629 3120 Membrane 313.0 5420.0 1.55E-6 0.021155894
HLA-DRA ENSG00000204287 3122 Membrane 1506.0 66500.0 1.55E-6 0.002400145
HLA-DRB1 ENSG00000196126 3123 Membrane 1418.0 68300.0 1.55E-6 0.002592935
HLA-DRB3 NA 3125 Membrane 1070.0 10800.0 1.55E-6 0.002876302
HLA-DRB4 NA 3126 Membrane 1074.0 13300.0 1.55E-6 0.002873997
HLA-DRB5 ENSG00000198502 3127 Membrane 900.0 11400.0 1.55E-6 0.004177481
HLA-E ENSG00000204592 3133 Membrane 491.0 25500.0 1.55E-6 0.011737811
HLA-F ENSG00000204642 3134 Membrane 344.0 3710.0 1.54E-6 0.007475083
HLA-G ENSG00000204632 3135 Membrane 363.0 3510.0 1.54E-6 0.006605482
ICAM1 ENSG00000090339 3383 Membrane 359.0 4550.0 1.56E-6 0.005711085
IFNGR1 ENSG00000027697 3459 Membrane 1103.0 1620.0 1.55E-6 0.008258289
IFNGR2 ENSG00000159128 3460 Membrane 850.0 332.0 1.55E-6 0.011892192
PTAFR ENSG00000169403 5724 Membrane 38.0 2.1 1.54E-6 0.385490754
VCAM1 ENSG00000162692 7412 Membrane 244.0 14800.0 1.55E-6 0.020306281
HLA-H ENSG00000206341 3136 Unknown 47.0 1050.0 1.54E-6 0.110083256
IRF5 ENSG00000128604 3663 Unknown 30.0 370.0 1.55E-6 0.172413793
MID1 ENSG00000101871 4281 Unknown 1.0 0.0 1.52E-6 0.0
PML ENSG00000140464 5371 Unknown 653.0 17600.0 1.56E-6 0.012824247
SP100 ENSG00000067066 6672 Unknown 39.0 53.3 1.54E-6 0.684210526
TRIM34 ENSG00000258659 53840 Unknown 1.0 0.0 1.5E-6 0.0
CAMK2A ENSG00000070808 815 Nucleus 3480.0 132000.0 1.56E-6 0.001018591
CIITA ENSG00000179583 4261 Nucleus 24.0 4700.0 1.54E-6 0.076086957
IRF2 ENSG00000168310 3660 Nucleus 97.0 3730.0 1.55E-6 0.025343643
IRF3 ENSG00000126456 3661 Nucleus 760.0 29300.0 1.55E-6 0.001608765
IRF6 ENSG00000117595 3664 Nucleus 8.0 39.7 1.54E-6 0.0
TRIM10 ENSG00000204613 10107 Nucleus 1.0 0.0 1.51E-6 0.0
TRIM26 ENSG00000234127 7726 Nucleus 1.0 0.0 1.53E-6 0.0
TRIM6 ENSG00000121236 117854 Nucleus 1.0 0.0 1.5E-6 0.0
TRIM8 ENSG00000171206 81603 Nucleus 5.0 10200.0 1.54E-6 0.2
B2M ENSG00000166710 567 Secreted 373.0 49300.0 1.55E-6 0.027256479
IFNG ENSG00000111537 3458 Secreted/Nucleus 2810.0 62900.0 1.56E-6 0.00158109
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
CAMK2B ENSG00000058404 816 Cytoplasm 887.0 59300.0 3.99E-7 0.003977696
GBP1 ENSG00000117228 2633 Cytoplasm 2.0 0.0537 3.98E-7 0.0
IFI30 ENSG00000216490 10437 Cytoplasm 2.0 8170.0 3.97E-7 0.0
JAK1 ENSG00000162434 3716 Cytoplasm 1166.0 103000.0 3.99E-7 0.00296822
PRKCD ENSG00000163932 5580 Cytoplasm 168.0 111000.0 3.99E-7 0.078913601
PTPN6 ENSG00000111679 5777 Cytoplasm 640.0 24100.0 3.99E-7 0.01034331
SOCS1 ENSG00000185338 8651 Cytoplasm 271.0 17600.0 3.99E-7 0.025802925
TRIM2 ENSG00000109654 23321 Cytoplasm 1.0 0.0 3.97E-7 0.0
TRIM29 ENSG00000137699 23650 Cytoplasm 1.0 0.0 3.97E-7 0.0
TRIM5 ENSG00000132256 85363 Cytoplasm 4.0 32700.0 3.97E-7 0.0
CAMK2D ENSG00000145349 817 Cytoplasm/Nucleus 910.0 61900.0 3.99E-7 0.003812909
CAMK2G ENSG00000148660 818 Cytoplasm/Nucleus 898.0 60600.0 3.99E-7 0.003910585
IRF1 ENSG00000125347 3659 Cytoplasm/Nucleus 112.0 59300.0 3.99E-7 0.031370656
IRF4 ENSG00000137265 3662 Cytoplasm/Nucleus 2.0 0.0 3.98E-7 0.0
IRF7 ENSG00000185507 3665 Cytoplasm/Nucleus 302.0 40000.0 3.99E-7 0.006512508
IRF8 ENSG00000140968 3394 Cytoplasm/Nucleus 19.0 16400.0 3.98E-7 0.099415205
IRF9 ENSG00000213928 10379 Cytoplasm/Nucleus 27.0 1.73 3.98E-7 0.034188034
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 1514.0 312000.0 3.99E-7 0.002375712
OASL ENSG00000135114 8638 Cytoplasm/Nucleus 2.0 0.0 3.98E-7 0.0
SOCS3 ENSG00000184557 9021 Cytoplasm/Nucleus 402.0 12200.0 3.99E-7 0.008957705
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 564.0 51700.0 3.99E-7 0.00553645
TRIM21 ENSG00000132109 6737 Cytoplasm/Nucleus 76.0 48100.0 3.99E-7 0.226666667
TRIM25 ENSG00000121060 7706 Cytoplasm/Nucleus 167.0 13100.0 3.99E-7 0.02712647
TRIM35 ENSG00000104228 23087 Cytoplasm/Nucleus 2.0 8170.0 3.96E-7 0.0
TRIM68 ENSG00000167333 55128 Cytoplasm/Nucleus 1.0 0.0 3.96E-7 0.0
CD44 ENSG00000026508 960 Membrane 101.0 86100.0 3.99E-7 0.201584158
FCGR1A ENSG00000150337 2209 Membrane 144.0 8550.0 3.99E-7 0.122571873
HLA-A ENSG00000206503 3105 Membrane 195.0 50500.0 3.99E-7 0.027279937
HLA-B ENSG00000234745 3106 Membrane 209.0 28400.0 3.99E-7 0.023371365
HLA-C ENSG00000204525 3107 Membrane 208.0 39200.0 3.99E-7 0.019695281
HLA-DPA1 ENSG00000231389 3113 Membrane 396.0 19400.0 3.99E-7 0.022017645
HLA-DPB1 ENSG00000223865 3115 Membrane 370.0 18800.0 3.99E-7 0.023291584
HLA-DQA1 ENSG00000196735 3117 Membrane 393.0 31300.0 3.99E-7 0.022173755
HLA-DQA2 ENSG00000237541 3118 Membrane 393.0 17700.0 3.99E-7 0.021797269
HLA-DQB1 ENSG00000179344 3119 Membrane 380.0 17800.0 3.99E-7 0.02178864
HLA-DQB2 ENSG00000232629 3120 Membrane 211.0 14800.0 3.99E-7 0.045317084
HLA-DRA ENSG00000204287 3122 Membrane 425.0 33200.0 3.99E-7 0.019278579
HLA-DRB1 ENSG00000196126 3123 Membrane 397.0 37100.0 3.99E-7 0.020698166
HLA-DRB3 NA 3125 Membrane 367.0 17400.0 3.99E-7 0.023361772
HLA-DRB4 NA 3126 Membrane 367.0 17400.0 3.99E-7 0.023361772
HLA-DRB5 ENSG00000198502 3127 Membrane 369.0 19500.0 3.99E-7 0.023550725
HLA-E ENSG00000204592 3133 Membrane 251.0 50300.0 3.99E-7 0.032796813
HLA-F ENSG00000204642 3134 Membrane 164.0 6860.0 3.99E-7 0.02970223
HLA-G ENSG00000204632 3135 Membrane 175.0 6090.0 3.99E-7 0.025221675
ICAM1 ENSG00000090339 3383 Membrane 57.0 279.0 3.98E-7 0.006265664
IFNGR1 ENSG00000027697 3459 Membrane 116.0 59.2 3.99E-7 0.011844078
IFNGR2 ENSG00000159128 3460 Membrane 94.0 20.3 3.99E-7 0.016929764
PTAFR ENSG00000169403 5724 Membrane 26.0 4.39 3.98E-7 0.624615385
VCAM1 ENSG00000162692 7412 Membrane 47.0 1290.0 3.98E-7 0.027752081
HLA-H ENSG00000206341 3136 Unknown 47.0 1610.0 3.98E-7 0.110083256
IRF5 ENSG00000128604 3663 Unknown 6.0 1670.0 3.98E-7 0.133333333
MID1 ENSG00000101871 4281 Unknown 1.0 0.0 3.97E-7 0.0
PML ENSG00000140464 5371 Unknown 78.0 7330.0 3.99E-7 0.24042624
SP100 ENSG00000067066 6672 Unknown 39.0 8170.0 3.98E-7 0.684210526
TRIM34 ENSG00000258659 53840 Unknown 1.0 0.0 3.96E-7 0.0
CAMK2A ENSG00000070808 815 Nucleus 1081.0 135000.0 3.99E-7 0.003064721
CIITA ENSG00000179583 4261 Nucleus 4.0 0.0537 3.98E-7 0.833333333
IRF2 ENSG00000168310 3660 Nucleus 83.0 9990.0 3.99E-7 0.031148986
IRF3 ENSG00000126456 3661 Nucleus 388.0 57800.0 3.99E-7 0.003796052
IRF6 ENSG00000117595 3664 Nucleus 4.0 5.77 3.97E-7 0.0
TRIM10 ENSG00000204613 10107 Nucleus 1.0 0.0 3.95E-7 0.0
TRIM26 ENSG00000234127 7726 Nucleus 1.0 0.0 3.98E-7 0.0
TRIM6 ENSG00000121236 117854 Nucleus 1.0 0.0 3.96E-7 0.0
TRIM8 ENSG00000171206 81603 Nucleus 5.0 8170.0 3.98E-7 0.2
B2M ENSG00000166710 567 Secreted 233.0 89000.0 3.99E-7 0.047617286
IFNG ENSG00000111537 3458 Secreted/Nucleus 113.0 5210.0 3.99E-7 0.015012642
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
B2M HLA-A 6
B2M HLA-B 6
B2M HLA-C 5
B2M HLA-E 5
B2M HLA-F 3
B2M HLA-G 4
B2M PTPN6 1
CAMK2A CAMK2B 5
CAMK2A CAMK2D 6
CAMK2A CAMK2G 5
CAMK2A CD44 1
CAMK2A STAT1 3
CAMK2B CAMK2D 4
CAMK2B CAMK2G 3
CAMK2B STAT1 3
CAMK2D CAMK2G 4
CAMK2D IFNGR2 3
CAMK2D STAT1 4
CAMK2G STAT1 4
HLA-A HLA-B 4
HLA-A HLA-C 3
HLA-A HLA-E 2
HLA-A HLA-G 2
HLA-A PTPN6 1
HLA-B HLA-C 3
HLA-B HLA-E 2
HLA-C HLA-E 2
HLA-C HLA-F 2
HLA-C HLA-G 2
HLA-DPA1 HLA-DPB1 4
HLA-DPA1 HLA-DQB1 2
HLA-DPA1 HLA-DRB1 2
HLA-DPA1 HLA-DRB3 2
HLA-DPA1 HLA-DRB4 2
HLA-DPA1 HLA-DRB5 2
HLA-DPB1 HLA-DQA1 2
HLA-DPB1 HLA-DQA2 2
HLA-DPB1 HLA-DRA 2
HLA-DQA1 HLA-DQB1 5
HLA-DQA1 HLA-DRB1 2
HLA-DQA1 HLA-DRB3 2
HLA-DQA1 HLA-DRB4 2
HLA-DQA1 HLA-DRB5 2
HLA-DQA2 HLA-DQB1 3
HLA-DQA2 HLA-DRB1 2
HLA-DQA2 HLA-DRB3 2
HLA-DQA2 HLA-DRB4 2
HLA-DQA2 HLA-DRB5 2
HLA-DQB1 HLA-DRA 2
HLA-DRA HLA-DRB1 8
HLA-DRA HLA-DRB3 2
HLA-DRA HLA-DRB4 3
HLA-DRA HLA-DRB5 4
HLA-DRB1 HLA-DRB3 2
HLA-E HLA-F 3
HLA-E HLA-G 2
HLA-F HLA-G 2
IFNG IFNGR1 10
IFNG IFNGR2 6
IFNG IRF1 2
IFNG JAK1 5
IFNG JAK2 5
IFNGR1 IFNGR2 4
IFNGR1 JAK1 7
IFNGR1 JAK2 8
IFNGR1 SOCS1 3
IFNGR1 STAT1 8
IFNGR2 JAK1 4
IFNGR2 JAK2 6
IFNGR2 STAT1 3
IFNG STAT1 4
IRF1 IRF2 2
IRF1 IRF9 2
IRF3 IRF7 3
IRF7 TRIM21 2
IRF9 STAT1 7
JAK1 JAK2 4
JAK1 SOCS1 7
JAK1 SOCS3 7
JAK1 STAT1 9
JAK2 SOCS1 8
JAK2 SOCS3 8
JAK2 STAT1 11
PRKCD STAT1 6
PTPN6 IFNGR1 3
PTPN6 IFNGR2 3
PTPN6 JAK1 4
PTPN6 JAK2 5
PTPN6 STAT1 2
SOCS1 IFNGR2 2
SOCS3 IFNGR1 3
SOCS3 IFNGR2 3
SOCS3 STAT1 2
STAT1 SOCS1 2
B2M FCGR1A 1
B2M HLA-H 1
CAMK2A IFNGR2 1
CAMK2A PRKCD 1
CAMK2B IFNGR2 1
CAMK2B PRKCD 1
CAMK2D PRKCD 1
CAMK2G IFNGR2 1
CAMK2G PRKCD 1
HLA-A HLA-DPA1 1
HLA-A HLA-DQA1 1
HLA-A HLA-DRB5 1
HLA-B STAT1 1
HLA-DPA1 HLA-DQB2 1
HLA-DPA1 HLA-F 1
HLA-DPB1 HLA-E 1
HLA-DQA1 HLA-DPA1 1
HLA-DQA1 HLA-DQB2 1
HLA-DQA2 HLA-DPA1 1
HLA-DQA2 HLA-DQA1 1
HLA-DQA2 HLA-DQB2 1
HLA-DQB1 HLA-DPB1 1
HLA-DQB2 HLA-DRA 1
HLA-DRA CAMK2A 1
HLA-DRA HLA-DPA1 1
HLA-DRA HLA-DQA1 1
HLA-DRA HLA-DQA2 1
HLA-DRA PRKCD 1
HLA-DRB1 CAMK2A 1
HLA-DRB1 HLA-DPB1 1
HLA-DRB1 HLA-DQB1 1
HLA-DRB1 IFNG 1
HLA-DRB1 PRKCD 1
HLA-DRB1 TRIM21 1
HLA-DRB3 HLA-DPB1 1
HLA-DRB3 HLA-DQB1 1
HLA-DRB4 HLA-DPB1 1
HLA-DRB4 HLA-DQB1 1
HLA-DRB4 HLA-DRB1 1
HLA-DRB4 HLA-DRB3 1
HLA-DRB5 HLA-DPB1 1
HLA-DRB5 HLA-DQB1 1
HLA-DRB5 HLA-DRB1 1
HLA-DRB5 HLA-DRB3 1
HLA-DRB5 HLA-DRB4 1
HLA-DRB5 STAT1 1
HLA-E FCGR1A 1
HLA-F HLA-A 1
HLA-F HLA-B 1
HLA-G HLA-B 1
IFI30 TRIM68 1
IFNG CAMK2A 1
IFNG CAMK2B 1
IFNG CAMK2D 1
IFNG CAMK2G 1
IFNG CIITA 1
IFNG GBP1 1
IFNG HLA-DRA 1
IFNG ICAM1 1
IFNGR1 CAMK2A 1
IFNGR1 CAMK2B 1
IFNGR1 CAMK2D 1
IFNGR1 CAMK2G 1
IFNG SOCS1 2
IFNG VCAM1 1
IRF1 B2M 1
IRF1 CIITA 1
IRF1 HLA-C 1
IRF1 HLA-DQA1 1
IRF1 HLA-F 1
IRF1 IRF8 2
IRF1 SOCS1 1
IRF1 STAT1 3
IRF1 TRIM21 1
IRF1 TRIM8 1
IRF2 B2M 1
IRF2 CIITA 1
IRF2 GBP1 1
IRF2 HLA-B 1
IRF2 IRF8 2
IRF2 STAT1 1
IRF3 IRF5 2
IRF3 SOCS1 1
IRF3 TRIM21 1
IRF3 TRIM26 1
IRF5 IRF6 2
IRF5 TRIM21 1
IRF6 IRF8 2
IRF7 IRF2 1
IRF7 OASL 1
IRF8 B2M 1
IRF8 HLA-B 1
IRF8 MID1 2
IRF8 TRIM21 1
JAK1 CAMK2A 1
JAK1 CAMK2B 1
JAK1 CAMK2D 1
JAK1 CAMK2G 1
JAK1 IRF4 1
JAK1 PML 1
JAK2 CAMK2A 1
JAK2 CAMK2B 1
JAK2 CAMK2D 1
JAK2 CAMK2G 1
JAK2 PTAFR 2
PML SP100 1
PML STAT1 1
PRKCD ICAM1 1
PRKCD IFNG 1
PRKCD IFNGR1 1
PRKCD IFNGR2 1
PRKCD JAK1 1
PRKCD JAK2 1
PRKCD PTPN6 2
PRKCD VCAM1 1
PTPN6 HLA-DPA1 1
PTPN6 HLA-DPB1 1
PTPN6 HLA-DQA1 1
PTPN6 HLA-DQA2 1
PTPN6 HLA-DQB1 1
PTPN6 HLA-DQB2 1
PTPN6 HLA-DRA 2
PTPN6 HLA-DRB1 2
PTPN6 HLA-DRB3 1
PTPN6 HLA-DRB4 1
PTPN6 HLA-DRB5 1
PTPN6 IFNG 1
PTPN6 SOCS3 1
SOCS1 TRIM8 1
SOCS3 IFNG 1
SP100 TRIM29 1
STAT1 CIITA 1
STAT1 VCAM1 1
TRIM10 TRIM35 1
TRIM21 TRIM5 1
TRIM21 TRIM8 2
TRIM25 IRF3 1
TRIM25 IRF7 1
TRIM25 TRIM8 2
TRIM2 TRIM8 2
TRIM34 TRIM5 2
TRIM35 TRIM5 1
TRIM5 TRIM6 2
Pathway1 Pathway2 Intersect Similarity Scores Pathway Name Source Number of Genes Number of Interactions Detail
pathway0001181 pathway0001084 6 1.0 IFN gamma signaling pathway(JAK1 JAK2 STAT1) ( IFN gamma signaling(JAK1 JAK2 STAT1) ) INOH 6 18
pathway0001181 pathway0000668 8 0.6666667 Endosomal/Vacuolar pathway Reactome 12 31
pathway0001181 pathway0001841 9 0.6428571 Regulation of IFNG signaling Reactome 14 63
pathway0001181 pathway0001227 3 0.6 JAK degradation signaling ( JAK-STAT pathway and regulation pathway Diagram ) INOH 5 12
pathway0001181 pathway0001454 3 0.6 Negative regulation of (Phosphorylation of JAK) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH 5 12
pathway0001181 pathway0002675 17 0.5151515 Graft-versus-host disease KEGG 33 160
pathway0001181 pathway0002815 5 0.5 Hs_Type_II_interferon_signaling_(IFNG)_WP619_71168 WikiPathways 10 14