Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0001322 MAPK6/MAPK4 signaling Reactome Homo sapiens 90 1485
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
CDC42EP2 ENSG00000149798 10435 Cytoplasm 0.004347826 8.0 0.9556662 0.107142857
CDC42EP3 ENSG00000163171 10602 Cytoplasm 0.005524862 11.0 7.962469 0.236363636
CDC42EP5 ENSG00000167617 148170 Cytoplasm 0.005263158 10.0 6.419095 0.177777778
PAK2 ENSG00000180370 5062 Cytoplasm 0.005952381 37.0 24.4931 0.046546547
PAK3 ENSG00000077264 5063 Cytoplasm 0.004237288 20.0 1.085722 0.005263158
PRKACB ENSG00000142875 5567 Cytoplasm 0.005319149 8.0 6.433181 0.285714286
PRKACG ENSG00000165059 5568 Cytoplasm 0.004149378 5.0 0.0 0.3
PSMB10 ENSG00000205220 5699 Cytoplasm 0.007194245 74.0 1.176381 0.431321733
PSMB2 ENSG00000126067 5690 Cytoplasm 0.006849315 92.0 5.784902 0.27090301
PSMB4 ENSG00000159377 5692 Cytoplasm 0.007462687 95.0 3.850273 0.267861142
PSMB6 ENSG00000142507 5694 Cytoplasm 0.007194245 92.0 1.240051 0.278308648
PSMC6 ENSG00000100519 5706 Cytoplasm 0.007462687 94.0 3.432077 0.273621597
PSMD12 ENSG00000197170 5718 Cytoplasm 0.00729927 93.0 8.087656 0.275128565
PSMD13 ENSG00000185627 5719 Cytoplasm 0.007633588 93.0 14.96533 0.28401122
PSMD2 ENSG00000175166 5708 Cytoplasm 0.007575758 95.0 19.94565 0.271668533
PSMD3 ENSG00000108344 5709 Cytoplasm 0.007692308 95.0 24.98719 0.274580067
PSMD4 ENSG00000159352 5710 Cytoplasm 0.007194245 93.0 2.147077 0.272323516
PSMD5 ENSG00000095261 5711 Cytoplasm 0.007633588 88.0 11.96493 0.31400209
PSMD6 ENSG00000163636 9861 Cytoplasm 0.007246377 93.0 7.262471 0.27372604
PSMD8 ENSG00000099341 5714 Cytoplasm 0.007575758 92.0 8.790491 0.288819876
RAC1 ENSG00000136238 5879 Cytoplasm 0.005617978 45.0 18.2029 0.011111111
RPS27A ENSG00000143947 6233 Cytoplasm 0.007692308 104.0 31.38923 0.226848394
UBA52 ENSG00000221983 7311 Cytoplasm 0.007692308 98.0 34.65428 0.249526615
UBC ENSG00000150991 7316 Cytoplasm 0.008333333 135.0 272.0271 0.139524599
SEPT7 ENSG00000122545 989 Cytoplasm/Nucleus 0.004464286 12.0 3.108413 0.121212121
CCND3 ENSG00000112576 896 Cytoplasm/Nucleus 0.005494505 7.0 1.606389 0.380952381
CDK1 ENSG00000170312 983 Cytoplasm/Nucleus 0.008403361 69.0 198.5456 0.532821824
DNAJB1 ENSG00000132002 3337 Cytoplasm/Nucleus 0.005649718 8.0 2.131442 0.25
FOXO1 ENSG00000150907 2308 Cytoplasm/Nucleus 0.005649718 20.0 81.04307 0.031578947
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 0.00591716 18.0 8.913571 0.137254902
HSPB1 ENSG00000106211 3315 Cytoplasm/Nucleus 0.00591716 19.0 17.66501 0.216374269
IGF2BP1 ENSG00000159217 10642 Cytoplasm/Nucleus 0.005434783 9.0 4.815897 0.333333333
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 0.008547009 83.0 569.3967 0.249779606
KALRN ENSG00000160145 8997 Cytoplasm/Nucleus 0.005208333 11.0 3.01775 0.127272727
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 0.005780347 17.0 14.88133 0.066176471
MAPK6 ENSG00000069956 5597 Cytoplasm/Nucleus 0.006289308 41.0 147.7832 0.06097561
MAPKAPK5 ENSG00000089022 8550 Cytoplasm/Nucleus 0.005882353 36.0 107.4682 0.047619048
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 0.008 67.0 459.4103 0.272274989
NCOA3 ENSG00000124151 8202 Cytoplasm/Nucleus 0.006410256 29.0 123.311 0.268472906
PSMA1 ENSG00000129084 5682 Cytoplasm/Nucleus 0.007633588 98.0 17.22597 0.255628024
PSMA3 ENSG00000100567 5684 Cytoplasm/Nucleus 0.007633588 95.0 15.27169 0.272340426
PSMA4 ENSG00000041357 5685 Cytoplasm/Nucleus 0.007462687 94.0 3.425414 0.273621597
PSMA5 ENSG00000143106 5686 Cytoplasm/Nucleus 0.007462687 93.0 4.428372 0.279569892
PSMA6 ENSG00000100902 5687 Cytoplasm/Nucleus 0.007194245 94.0 1.240051 0.266529398
PSMA7 ENSG00000101182 5688 Cytoplasm/Nucleus 0.007751938 97.0 51.88498 0.257946735
PSMB3 ENSG00000277791 5691 Cytoplasm/Nucleus 0.007575758 95.0 11.34448 0.270772676
PSMB5 ENSG00000100804 5693 Cytoplasm/Nucleus 0.007633588 93.0 14.5158 0.28401122
PSMB7 ENSG00000136930 5695 Cytoplasm/Nucleus 0.007246377 93.0 8.373896 0.271856007
PSMB8 ENSG00000204264 5696 Cytoplasm/Nucleus 0.006711409 89.0 0.0 0.28804903
PSMC1 ENSG00000100764 5700 Cytoplasm/Nucleus 0.007518797 94.0 9.288581 0.275223061
PSMC2 ENSG00000161057 5701 Cytoplasm/Nucleus 0.007633588 96.0 32.8635 0.264035088
PSMC5 ENSG00000087191 5705 Cytoplasm/Nucleus 0.007692308 97.0 41.2344 0.260524055
PSMD1 ENSG00000173692 5707 Cytoplasm/Nucleus 0.007518797 96.0 20.22873 0.260745614
PSMD10 ENSG00000101843 5716 Cytoplasm/Nucleus 0.007142857 73.0 1.529164 0.440639269
PSMD11 ENSG00000108671 5717 Cytoplasm/Nucleus 0.00729927 92.0 31.35637 0.279025323
PSMD14 ENSG00000115233 10213 Cytoplasm/Nucleus 0.007575758 96.0 22.77788 0.265789474
PSMD9 ENSG00000110801 5715 Cytoplasm/Nucleus 0.006711409 64.0 0.0 0.55952381
PSME1 ENSG00000092010 5720 Cytoplasm/Nucleus 0.006802721 78.0 5.114468 0.376956377
PSME2 ENSG00000100911 5721 Cytoplasm/Nucleus 0.006711409 76.0 0.0 0.395789474
PSME3 ENSG00000131467 10197 Cytoplasm/Nucleus 0.007692308 88.0 29.53349 0.320010449
PSMF1 ENSG00000125818 9491 Cytoplasm/Nucleus 0.006711409 58.0 0.0 0.682395644
TNRC6A ENSG00000090905 27327 Cytoplasm/Nucleus 0.005813953 16.0 16.7203 0.241666667
XPO1 ENSG00000082898 7514 Cytoplasm/Nucleus 0.006410256 36.0 118.864 0.101587302
CDC42 ENSG00000070831 998 Membrane 0.005988024 50.0 103.76 0.029387755
AGO1 ENSG00000092847 26523 Unknown 0.005617978 14.0 4.049096 0.351648352
AGO2 ENSG00000123908 27161 Unknown 0.005681818 16.0 8.28564 0.35
AGO3 ENSG00000126070 192669 Unknown 0.005649718 14.0 5.453303 0.417582418
AGO4 ENSG00000134698 192670 Unknown 0.004975124 11.0 1.83364 0.363636364
MOV10 ENSG00000155363 4343 Unknown 0.00625 24.0 45.1819 0.460144928
PAK1 ENSG00000149269 5058 Unknown 0.005494505 44.0 23.3611 0.016913319
PRKACA ENSG00000072062 5566 Unknown 0.005882353 19.0 59.30132 0.128654971
PSMA2 ENSG00000106588 5683 Unknown 0.007518797 96.0 9.801655 0.263596491
PSMA8 ENSG00000154611 143471 Unknown 0.006849315 84.0 13.91704 0.323866896
PSMB1 ENSG00000008018 5689 Unknown 0.007462687 94.0 3.425414 0.273621597
PSMB11 ENSG00000222028 122706 Unknown 0.006711409 52.0 0.0 0.850678733
TNRC6B ENSG00000100354 23112 Unknown 0.005405405 11.0 1.353757 0.345454545
TNRC6C ENSG00000078687 57690 Unknown 0.005025126 11.0 0.9017493 0.327272727
CDC14A ENSG00000079335 8556 Nucleus 0.005405405 7.0 2.019916 0.285714286
CDC14B ENSG00000081377 8555 Nucleus 0.005025126 4.0 0.0 0.5
ETV4 ENSG00000175832 2118 Nucleus 0.005076142 7.0 9.194285 0.285714286
PSMB9 ENSG00000240065 5698 Nucleus 0.006944444 92.0 5.824555 0.272097468
PSMC3 ENSG00000165916 5702 Nucleus 0.007518797 93.0 6.485859 0.282608696
PSMC4 ENSG00000013275 5704 Nucleus 0.007633588 96.0 13.04164 0.267982456
PSMD7 ENSG00000103035 5713 Nucleus 0.007462687 95.0 4.759246 0.267861142
PSME4 ENSG00000068878 23198 Nucleus 0.007462687 70.0 3.215454 0.495238095
RAG1 ENSG00000166349 5896 Nucleus 0.004807692 7.0 21.47746 0.047619048
RAG2 ENSG00000175097 5897 Nucleus 0.003846154 6.0 0.0 0.066666667
UBB ENSG00000170315 7314 Nucleus 0.007751938 99.0 36.60064 0.250876108
MMP10 ENSG00000166670 4319 Secreted 0.004149378 2.0 0.0 1.0
MMP2 ENSG00000087245 4313 Secreted 0.005586592 7.0 1.178633 0.333333333
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
CDC42EP2 ENSG00000149798 10435 Cytoplasm 8.0 48.1 1.54E-6 0.107142857
CDC42EP3 ENSG00000163171 10602 Cytoplasm 11.0 248.0 1.55E-6 0.236363636
CDC42EP5 ENSG00000167617 148170 Cytoplasm 10.0 202.0 1.55E-6 0.177777778
PAK2 ENSG00000180370 5062 Cytoplasm 2174.0 15000.0 1.56E-6 0.001088461
PAK3 ENSG00000077264 5063 Cytoplasm 711.0 931.0 1.55E-6 0.002872368
PRKACB ENSG00000142875 5567 Cytoplasm 6037.0 134000.0 1.56E-6 1.64054E-4
PRKACG ENSG00000165059 5568 Cytoplasm 5482.0 69200.0 1.56E-6 1.32793E-4
PSMB10 ENSG00000205220 5699 Cytoplasm 3573.0 1680.0 1.55E-6 0.001074219
PSMB2 ENSG00000126067 5690 Cytoplasm 4371.0 2520.0 1.55E-6 7.41103E-4
PSMB4 ENSG00000159377 5692 Cytoplasm 4476.0 4030.0 1.55E-6 7.26207E-4
PSMB6 ENSG00000142507 5694 Cytoplasm 4379.0 2510.0 1.55E-6 7.35685E-4
PSMC6 ENSG00000100519 5706 Cytoplasm 4116.0 2700.0 1.55E-6 7.83712E-4
PSMD12 ENSG00000197170 5718 Cytoplasm 4410.0 4800.0 1.55E-6 7.37309E-4
PSMD13 ENSG00000185627 5719 Cytoplasm 4438.0 7430.0 1.56E-6 7.84606E-4
PSMD2 ENSG00000175166 5708 Cytoplasm 4474.0 9320.0 1.56E-6 7.73628E-4
PSMD3 ENSG00000108344 5709 Cytoplasm 4411.0 6590.0 1.56E-6 7.64734E-4
PSMD4 ENSG00000159352 5710 Cytoplasm 4475.0 6160.0 1.56E-6 7.59797E-4
PSMD5 ENSG00000095261 5711 Cytoplasm 4102.0 3340.0 1.55E-6 8.45544E-4
PSMD6 ENSG00000163636 9861 Cytoplasm 4442.0 6760.0 1.56E-6 7.36861E-4
PSMD8 ENSG00000099341 5714 Cytoplasm 4296.0 3700.0 1.55E-6 7.90729E-4
RAC1 ENSG00000136238 5879 Cytoplasm 14443.0 874000.0 1.56E-6 1.68851E-4
RPS27A ENSG00000143947 6233 Cytoplasm 8445.0 940000.0 1.56E-6 9.48793E-4
UBA52 ENSG00000221983 7311 Cytoplasm 7270.0 455000.0 1.56E-6 0.001103705
UBC ENSG00000150991 7316 Cytoplasm 7688.0 614000.0 1.56E-6 8.3164E-4
SEPT7 ENSG00000122545 989 Cytoplasm/Nucleus 12.0 10.6 1.54E-6 0.121212121
CCND3 ENSG00000112576 896 Cytoplasm/Nucleus 440.0 6110.0 1.56E-6 0.01065438
CDK1 ENSG00000170312 983 Cytoplasm/Nucleus 3973.0 427000.0 1.56E-6 0.003107329
DNAJB1 ENSG00000132002 3337 Cytoplasm/Nucleus 287.0 12200.0 1.55E-6 0.015033747
FOXO1 ENSG00000150907 2308 Cytoplasm/Nucleus 1320.0 45800.0 1.56E-6 0.001618536
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 1569.0 45500.0 1.56E-6 0.002198202
HSPB1 ENSG00000106211 3315 Cytoplasm/Nucleus 611.0 25100.0 1.56E-6 0.007222774
IGF2BP1 ENSG00000159217 10642 Cytoplasm/Nucleus 37.0 6020.0 1.55E-6 0.136636637
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 12667.0 3720000.0 1.57E-6 4.67389E-4
KALRN ENSG00000160145 8997 Cytoplasm/Nucleus 107.0 984.0 1.55E-6 0.048139658
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 56.0 7.73 1.55E-6 0.01948052
MAPK6 ENSG00000069956 5597 Cytoplasm/Nucleus 167.0 4470.0 1.55E-6 0.025611428
MAPKAPK5 ENSG00000089022 8550 Cytoplasm/Nucleus 340.0 5340.0 1.55E-6 0.006125282
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 4967.0 1640000.0 1.57E-6 0.001945908
NCOA3 ENSG00000124151 8202 Cytoplasm/Nucleus 654.0 57700.0 1.56E-6 0.041965804
PSMA1 ENSG00000129084 5682 Cytoplasm/Nucleus 4557.0 6260.0 1.56E-6 7.46375E-4
PSMA3 ENSG00000100567 5684 Cytoplasm/Nucleus 4474.0 12700.0 1.56E-6 7.6983E-4
PSMA4 ENSG00000041357 5685 Cytoplasm/Nucleus 4472.0 3110.0 1.55E-6 7.25206E-4
PSMA5 ENSG00000143106 5686 Cytoplasm/Nucleus 4380.0 3130.0 1.55E-6 7.57976E-4
PSMA6 ENSG00000100902 5687 Cytoplasm/Nucleus 4492.0 4490.0 1.55E-6 7.33137E-4
PSMA7 ENSG00000101182 5688 Cytoplasm/Nucleus 4513.0 5490.0 1.55E-6 7.21517E-4
PSMB3 ENSG00000277791 5691 Cytoplasm/Nucleus 4423.0 4910.0 1.56E-6 7.56091E-4
PSMB5 ENSG00000100804 5693 Cytoplasm/Nucleus 4368.0 8790.0 1.55E-6 7.75358E-4
PSMB7 ENSG00000136930 5695 Cytoplasm/Nucleus 4395.0 2180.0 1.55E-6 7.31476E-4
PSMB8 ENSG00000204264 5696 Cytoplasm/Nucleus 4276.0 5520.0 1.55E-6 7.49019E-4
PSMC1 ENSG00000100764 5700 Cytoplasm/Nucleus 4431.0 5750.0 1.55E-6 7.51019E-4
PSMC2 ENSG00000161057 5701 Cytoplasm/Nucleus 4485.0 8060.0 1.56E-6 7.37218E-4
PSMC5 ENSG00000087191 5705 Cytoplasm/Nucleus 4446.0 9070.0 1.56E-6 7.52841E-4
PSMD1 ENSG00000173692 5707 Cytoplasm/Nucleus 4464.0 6850.0 1.56E-6 7.52905E-4
PSMD10 ENSG00000101843 5716 Cytoplasm/Nucleus 3516.0 2680.0 1.55E-6 0.001152707
PSMD11 ENSG00000108671 5717 Cytoplasm/Nucleus 4277.0 7570.0 1.55E-6 7.83117E-4
PSMD14 ENSG00000115233 10213 Cytoplasm/Nucleus 4164.0 4430.0 1.56E-6 7.90206E-4
PSMD9 ENSG00000110801 5715 Cytoplasm/Nucleus 3155.0 3840.0 1.55E-6 0.001387215
PSME1 ENSG00000092010 5720 Cytoplasm/Nucleus 3476.0 1680.0 1.55E-6 0.001048754
PSME2 ENSG00000100911 5721 Cytoplasm/Nucleus 3435.0 1800.0 1.55E-6 0.001083098
PSME3 ENSG00000131467 10197 Cytoplasm/Nucleus 3739.0 4820.0 1.56E-6 9.8738E-4
PSMF1 ENSG00000125818 9491 Cytoplasm/Nucleus 2686.0 1670.0 1.55E-6 0.001763195
TNRC6A ENSG00000090905 27327 Cytoplasm/Nucleus 104.0 420.0 1.55E-6 0.022031367
XPO1 ENSG00000082898 7514 Cytoplasm/Nucleus 1432.0 194000.0 1.56E-6 0.008646335
CDC42 ENSG00000070831 998 Membrane 6876.0 628000.0 1.56E-6 5.19414E-4
AGO1 ENSG00000092847 26523 Unknown 269.0 5340.0 1.55E-6 0.076763025
AGO2 ENSG00000123908 27161 Unknown 255.0 30700.0 1.55E-6 0.096217385
AGO3 ENSG00000126070 192669 Unknown 114.0 1350.0 1.55E-6 0.017233349
AGO4 ENSG00000134698 192670 Unknown 101.0 587.0 1.55E-6 0.017623762
MOV10 ENSG00000155363 4343 Unknown 156.0 6520.0 1.56E-6 0.075682382
PAK1 ENSG00000149269 5058 Unknown 5363.0 83300.0 1.56E-6 2.48501E-4
PRKACA ENSG00000072062 5566 Unknown 11354.0 1170000.0 1.56E-6 1.8549E-4
PSMA2 ENSG00000106588 5683 Unknown 4529.0 3920.0 1.55E-6 7.20426E-4
PSMA8 ENSG00000154611 143471 Unknown 3549.0 1170.0 1.55E-6 9.09636E-4
PSMB1 ENSG00000008018 5689 Unknown 4447.0 4330.0 1.55E-6 7.39858E-4
PSMB11 ENSG00000222028 122706 Unknown 2283.0 1000.0 1.55E-6 0.002185494
TNRC6B ENSG00000100354 23112 Unknown 88.0 71.6 1.55E-6 0.020114943
TNRC6C ENSG00000078687 57690 Unknown 94.0 180.0 1.55E-6 0.017387326
CDC14A ENSG00000079335 8556 Nucleus 83.0 47.9 1.55E-6 0.064942698
CDC14B ENSG00000081377 8555 Nucleus 69.0 11.4 1.55E-6 0.062233589
ETV4 ENSG00000175832 2118 Nucleus 14.0 124.0 1.55E-6 0.164835165
PSMB9 ENSG00000240065 5698 Nucleus 4351.0 2980.0 1.55E-6 7.20035E-4
PSMC3 ENSG00000165916 5702 Nucleus 4399.0 6070.0 1.56E-6 7.65088E-4
PSMC4 ENSG00000013275 5704 Nucleus 4461.0 3750.0 1.56E-6 7.56029E-4
PSMD7 ENSG00000103035 5713 Nucleus 4495.0 6260.0 1.55E-6 7.18298E-4
PSME4 ENSG00000068878 23198 Nucleus 2886.0 1300.0 1.55E-6 0.001396811
RAG1 ENSG00000166349 5896 Nucleus 7.0 12.1 1.54E-6 0.047619048
RAG2 ENSG00000175097 5897 Nucleus 9.0 7.78 1.54E-6 0.111111111
UBB ENSG00000170315 7314 Nucleus 6474.0 494000.0 1.56E-6 0.001116923
MMP10 ENSG00000166670 4319 Secreted 22.0 10400.0 1.54E-6 0.082251082
MMP2 ENSG00000087245 4313 Secreted 292.0 22800.0 1.56E-6 0.013981076
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
CDC42EP2 ENSG00000149798 10435 Cytoplasm 8.0 170.0 3.99E-7 0.107142857
CDC42EP3 ENSG00000163171 10602 Cytoplasm 11.0 270.0 3.99E-7 0.236363636
CDC42EP5 ENSG00000167617 148170 Cytoplasm 10.0 524.0 3.99E-7 0.177777778
PAK2 ENSG00000180370 5062 Cytoplasm 423.0 22100.0 3.99E-7 0.01001647
PAK3 ENSG00000077264 5063 Cytoplasm 192.0 1420.0 3.99E-7 0.017506545
PRKACB ENSG00000142875 5567 Cytoplasm 1070.0 150000.0 3.99E-7 0.001019382
PRKACG ENSG00000165059 5568 Cytoplasm 1031.0 98500.0 3.99E-7 8.00429E-4
PSMB10 ENSG00000205220 5699 Cytoplasm 3298.0 3010.0 3.99E-7 0.001140754
PSMB2 ENSG00000126067 5690 Cytoplasm 4068.0 6930.0 3.99E-7 7.75482E-4
PSMB4 ENSG00000159377 5692 Cytoplasm 4166.0 6440.0 3.99E-7 7.44724E-4
PSMB6 ENSG00000142507 5694 Cytoplasm 4074.0 5440.0 3.99E-7 7.68137E-4
PSMC6 ENSG00000100519 5706 Cytoplasm 4116.0 6850.0 3.99E-7 7.62339E-4
PSMD12 ENSG00000197170 5718 Cytoplasm 4034.0 7970.0 3.99E-7 7.85291E-4
PSMD13 ENSG00000185627 5719 Cytoplasm 4024.0 7960.0 3.99E-7 8.11067E-4
PSMD2 ENSG00000175166 5708 Cytoplasm 4075.0 14500.0 3.99E-7 7.98359E-4
PSMD3 ENSG00000108344 5709 Cytoplasm 4034.0 12200.0 3.99E-7 8.03854E-4
PSMD4 ENSG00000159352 5710 Cytoplasm 4119.0 12600.0 3.99E-7 7.85755E-4
PSMD5 ENSG00000095261 5711 Cytoplasm 3809.0 12600.0 3.99E-7 8.8275E-4
PSMD6 ENSG00000163636 9861 Cytoplasm 4077.0 14200.0 3.99E-7 7.71099E-4
PSMD8 ENSG00000099341 5714 Cytoplasm 3992.0 10600.0 3.99E-7 8.13579E-4
RAC1 ENSG00000136238 5879 Cytoplasm 2834.0 1070000.0 4.0E-7 0.001619685
RPS27A ENSG00000143947 6233 Cytoplasm 8445.0 2060000.0 4.0E-7 8.7747E-4
UBA52 ENSG00000221983 7311 Cytoplasm 7270.0 873000.0 4.0E-7 0.001030852
UBC ENSG00000150991 7316 Cytoplasm 7682.0 1600000.0 4.0E-7 7.21493E-4
SEPT7 ENSG00000122545 989 Cytoplasm/Nucleus 12.0 12.4 3.98E-7 0.121212121
CCND3 ENSG00000112576 896 Cytoplasm/Nucleus 67.0 862.0 3.99E-7 0.102216192
CDK1 ENSG00000170312 983 Cytoplasm/Nucleus 1840.0 517000.0 4.0E-7 0.011163321
DNAJB1 ENSG00000132002 3337 Cytoplasm/Nucleus 220.0 22900.0 3.99E-7 0.019468659
FOXO1 ENSG00000150907 2308 Cytoplasm/Nucleus 103.0 24600.0 3.99E-7 0.012183514
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 101.0 2160.0 3.99E-7 0.012475248
HSPB1 ENSG00000106211 3315 Cytoplasm/Nucleus 146.0 21200.0 3.99E-7 0.027491734
IGF2BP1 ENSG00000159217 10642 Cytoplasm/Nucleus 14.0 7420.0 3.99E-7 0.175824176
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 1005.0 172000.0 4.0E-7 0.016782621
KALRN ENSG00000160145 8997 Cytoplasm/Nucleus 64.0 4940.0 3.99E-7 0.05109127
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 17.0 42.8 3.99E-7 0.066176471
MAPK6 ENSG00000069956 5597 Cytoplasm/Nucleus 41.0 2480.0 3.99E-7 0.06097561
MAPKAPK5 ENSG00000089022 8550 Cytoplasm/Nucleus 72.0 6210.0 3.99E-7 0.024256651
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 552.0 47500.0 3.99E-7 0.033318867
NCOA3 ENSG00000124151 8202 Cytoplasm/Nucleus 299.0 102000.0 3.99E-7 0.137729793
PSMA1 ENSG00000129084 5682 Cytoplasm/Nucleus 4216.0 18100.0 3.99E-7 7.58563E-4
PSMA3 ENSG00000100567 5684 Cytoplasm/Nucleus 4126.0 35700.0 3.99E-7 7.845E-4
PSMA4 ENSG00000041357 5685 Cytoplasm/Nucleus 4135.0 4850.0 3.99E-7 7.54179E-4
PSMA5 ENSG00000143106 5686 Cytoplasm/Nucleus 4047.0 4820.0 3.99E-7 7.92102E-4
PSMA6 ENSG00000100902 5687 Cytoplasm/Nucleus 4150.0 8740.0 3.99E-7 7.62675E-4
PSMA7 ENSG00000101182 5688 Cytoplasm/Nucleus 4171.0 17500.0 3.99E-7 7.47539E-4
PSMB3 ENSG00000277791 5691 Cytoplasm/Nucleus 4084.0 12200.0 3.99E-7 7.85009E-4
PSMB5 ENSG00000100804 5693 Cytoplasm/Nucleus 4011.0 16400.0 3.99E-7 8.17826E-4
PSMB7 ENSG00000136930 5695 Cytoplasm/Nucleus 4067.0 4070.0 3.99E-7 7.70663E-4
PSMB8 ENSG00000204264 5696 Cytoplasm/Nucleus 3975.0 20300.0 3.99E-7 7.85483E-4
PSMC1 ENSG00000100764 5700 Cytoplasm/Nucleus 4074.0 8630.0 3.99E-7 7.83323E-4
PSMC2 ENSG00000161057 5701 Cytoplasm/Nucleus 4123.0 23500.0 3.99E-7 7.68696E-4
PSMC5 ENSG00000087191 5705 Cytoplasm/Nucleus 4133.0 24300.0 3.99E-7 7.71422E-4
PSMD1 ENSG00000173692 5707 Cytoplasm/Nucleus 4080.0 8450.0 3.99E-7 7.80901E-4
PSMD10 ENSG00000101843 5716 Cytoplasm/Nucleus 3272.0 7300.0 3.99E-7 0.001189044
PSMD11 ENSG00000108671 5717 Cytoplasm/Nucleus 3951.0 21800.0 3.99E-7 8.18764E-4
PSMD14 ENSG00000115233 10213 Cytoplasm/Nucleus 4112.0 16800.0 3.99E-7 7.75655E-4
PSMD9 ENSG00000110801 5715 Cytoplasm/Nucleus 2938.0 12800.0 3.99E-7 0.001446765
PSME1 ENSG00000092010 5720 Cytoplasm/Nucleus 3470.0 3720.0 3.99E-7 0.001032446
PSME2 ENSG00000100911 5721 Cytoplasm/Nucleus 3429.0 5270.0 3.99E-7 0.001062732
PSME3 ENSG00000131467 10197 Cytoplasm/Nucleus 3698.0 14400.0 3.99E-7 9.59368E-4
PSMF1 ENSG00000125818 9491 Cytoplasm/Nucleus 2686.0 4700.0 3.99E-7 0.001731857
TNRC6A ENSG00000090905 27327 Cytoplasm/Nucleus 104.0 1100.0 3.99E-7 0.017923824
XPO1 ENSG00000082898 7514 Cytoplasm/Nucleus 855.0 66600.0 3.99E-7 0.016549571
CDC42 ENSG00000070831 998 Membrane 1354.0 787000.0 4.0E-7 0.007763262
AGO1 ENSG00000092847 26523 Unknown 269.0 10300.0 3.99E-7 0.076180436
AGO2 ENSG00000123908 27161 Unknown 255.0 69200.0 3.99E-7 0.095599815
AGO3 ENSG00000126070 192669 Unknown 114.0 1980.0 3.99E-7 0.016767583
AGO4 ENSG00000134698 192670 Unknown 101.0 2350.0 3.99E-7 0.017029703
MOV10 ENSG00000155363 4343 Unknown 156.0 38000.0 3.99E-7 0.069644334
PAK1 ENSG00000149269 5058 Unknown 639.0 32800.0 3.99E-7 0.004905784
PRKACA ENSG00000072062 5566 Unknown 1889.0 878000.0 4.0E-7 0.003656315
PSMA2 ENSG00000106588 5683 Unknown 4192.0 8150.0 3.99E-7 7.43596E-4
PSMA8 ENSG00000154611 143471 Unknown 3525.0 3220.0 3.99E-7 9.08381E-4
PSMB1 ENSG00000008018 5689 Unknown 4113.0 8570.0 3.99E-7 7.75869E-4
PSMB11 ENSG00000222028 122706 Unknown 2283.0 2600.0 3.99E-7 0.002162845
TNRC6B ENSG00000100354 23112 Unknown 88.0 431.0 3.99E-7 0.018547544
TNRC6C ENSG00000078687 57690 Unknown 90.0 594.0 3.99E-7 0.016978777
CDC14A ENSG00000079335 8556 Nucleus 23.0 27.6 3.98E-7 0.300395257
CDC14B ENSG00000081377 8555 Nucleus 4.0 0.0 3.98E-7 0.5
ETV4 ENSG00000175832 2118 Nucleus 7.0 334.0 3.99E-7 0.285714286
PSMB9 ENSG00000240065 5698 Nucleus 4053.0 9630.0 3.99E-7 7.54076E-4
PSMC3 ENSG00000165916 5702 Nucleus 4034.0 8210.0 3.99E-7 7.98199E-4
PSMC4 ENSG00000013275 5704 Nucleus 4128.0 10300.0 3.99E-7 7.75992E-4
PSMD7 ENSG00000103035 5713 Nucleus 4101.0 5720.0 3.99E-7 7.62812E-4
PSME4 ENSG00000068878 23198 Nucleus 2886.0 2770.0 3.99E-7 0.00137231
RAG1 ENSG00000166349 5896 Nucleus 7.0 594.0 3.98E-7 0.047619048
RAG2 ENSG00000175097 5897 Nucleus 6.0 0.0 3.98E-7 0.066666667
UBB ENSG00000170315 7314 Nucleus 6348.0 955000.0 4.0E-7 0.001001917
MMP10 ENSG00000166670 4319 Secreted 22.0 15100.0 3.98E-7 0.077922078
MMP2 ENSG00000087245 4313 Secreted 82.0 58900.0 3.99E-7 0.031918097
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
AGO1 MOV10 2
AGO1 TNRC6A 4
AGO1 TNRC6B 4
AGO1 TNRC6C 3
AGO2 TNRC6A 5
AGO2 TNRC6B 4
AGO2 TNRC6C 4
AGO3 TNRC6A 3
AGO3 TNRC6B 3
AGO3 TNRC6C 3
AGO4 TNRC6A 3
AGO4 TNRC6B 3
AGO4 TNRC6C 3
CCND3 MAPK6 2
CDC14A MAPK6 1
CDC14B MAPK6 1
CDC42 PAK1 11
CDC42 PAK2 7
CDC42 PAK3 6
CDC42 RAC1 4
CDC42 RPS27A 3
CDC42 UBC 3
CDC42 XPO1 1
CDK1 FOXO1 2
CDK1 MAPK6 2
CDK1 NCOA3 1
CDK1 UBC 2
CDK1 XPO1 2
FOXO1 PAK1 2
FOXO1 RAG1 1
FOXO1 RAG2 1
IGF2BP1 MAPK4 1
JUN MMP2 3
JUN MYC 4
JUN PSMA1 2
JUN PSMA5 2
JUN PSMD1 2
JUN PSMD11 2
JUN PSMD12 3
JUN PSMD2 2
JUN PSMD4 3
JUN PSMD7 2
JUN PSME4 2
JUN TNRC6A 2
KALRN PAK1 1
KALRN RAC1 4
MAPK4 MAPKAPK5 4
MAPK6 CDC42EP2 1
MAPK6 CDC42EP3 1
MAPK6 CDC42EP5 1
MAPK6 JUN 1
MAPK6 MAPKAPK5 4
MAPK6 MYC 1
MAPK6 NCOA3 2
MAPKAPK5 CDC42EP2 1
MAPKAPK5 CDC42EP3 1
MAPKAPK5 CDC42EP5 1
MAPKAPK5 DNAJB1 2
MAPKAPK5 FOXO1 1
MAPKAPK5 FOXO3 1
MAPKAPK5 KALRN 2
MYC PSMB3 3
MYC PSME3 2
MYC XPO1 2
PAK1 JUN 1
PAK1 MAPK4 1
PAK1 MAPK6 1
PAK1 RAC1 9
PAK2 JUN 1
PAK2 MAPK4 1
PAK2 MAPK6 2
PAK2 RAC1 6
PAK3 MAPK4 1
PAK3 MAPK6 1
PAK3 RAC1 5
PRKACA MAPKAPK5 2
PRKACA NCOA3 1
PRKACA PRKACB 4
PRKACA PRKACG 3
PRKACA PSMC5 1
PRKACA PSMD11 1
PRKACB MAPKAPK5 1
PRKACG MAPKAPK5 1
PSMA1 PSMA2 6
PSMA1 PSMA3 6
PSMA1 PSMA4 6
PSMA1 PSMA5 6
PSMA1 PSMA6 6
PSMA1 PSMA7 6
PSMA1 PSMA8 2
PSMA1 PSMB1 6
PSMA1 PSMB10 4
PSMA1 PSMB2 6
PSMA1 PSMB3 6
PSMA1 PSMB4 6
PSMA1 PSMB5 6
PSMA1 PSMB6 6
PSMA1 PSMB7 6
PSMA1 PSMB8 3
PSMA1 PSMB9 3
PSMA1 PSMC1 4
PSMA1 PSMC2 4
PSMA1 PSMC3 4
PSMA1 PSMC4 4
PSMA1 PSMC5 4
PSMA1 PSMC6 4
PSMA1 PSMD1 4
PSMA1 PSMD11 3
PSMA1 PSMD12 3
PSMA1 PSMD13 5
PSMA1 PSMD14 4
PSMA1 PSMD2 4
PSMA1 PSMD3 3
PSMA1 PSMD4 3
PSMA1 PSMD5 3
PSMA1 PSMD6 4
PSMA1 PSMD7 4
PSMA1 PSMD8 3
PSMA1 PSME1 3
PSMA1 PSME2 3
PSMA1 PSME3 3
PSMA1 PSME4 2
PSMA1 PSMF1 2
PSMA1 RPS27A 1
PSMA1 UBA52 1
PSMA1 UBB 1
PSMA1 UBC 2
PSMA2 PSMA3 6
PSMA2 PSMA4 6
PSMA2 PSMA5 6
PSMA2 PSMA6 6
PSMA2 PSMA7 6
PSMA2 PSMA8 2
PSMA2 PSMB1 6
PSMA2 PSMB10 3
PSMA2 PSMB2 6
PSMA2 PSMB3 6
PSMA2 PSMB4 6
PSMA2 PSMB5 6
PSMA2 PSMB6 6
PSMA2 PSMB7 6
PSMA2 PSMB8 3
PSMA2 PSMB9 3
PSMA2 PSMC1 4
PSMA2 PSMC2 4
PSMA2 PSMC3 4
PSMA2 PSMC4 4
PSMA2 PSMC5 4
PSMA2 PSMC6 4
PSMA2 PSMD1 4
PSMA2 PSMD11 4
PSMA2 PSMD12 4
PSMA2 PSMD13 4
PSMA2 PSMD14 3
PSMA2 PSMD2 4
PSMA2 PSMD3 4
PSMA2 PSMD4 4
PSMA2 PSMD5 3
PSMA2 PSMD6 5
PSMA2 PSMD7 3
PSMA2 PSMD8 4
PSMA2 PSME1 3
PSMA2 PSME2 3
PSMA2 PSME4 2
PSMA2 PSMF1 2
PSMA2 RPS27A 1
PSMA2 UBA52 1
PSMA2 UBB 2
PSMA2 UBC 2
PSMA3 PSMA4 6
PSMA3 PSMA5 6
PSMA3 PSMA6 6
PSMA3 PSMA7 6
PSMA3 PSMA8 2
PSMA3 PSMB1 6
PSMA3 PSMB10 3
PSMA3 PSMB2 5
PSMA3 PSMB3 6
PSMA3 PSMB4 6
PSMA3 PSMB5 6
PSMA3 PSMB6 6
PSMA3 PSMB7 6
PSMA3 PSMB8 3
PSMA3 PSMB9 3
PSMA3 PSMC1 4
PSMA3 PSMC2 4
PSMA3 PSMC3 4
PSMA3 PSMC4 4
PSMA3 PSMC5 4
PSMA3 PSMC6 4
PSMA3 PSMD1 4
PSMA3 PSMD11 4
PSMA3 PSMD12 4
PSMA3 PSMD13 5
PSMA3 PSMD14 3
PSMA3 PSMD2 4
PSMA3 PSMD3 4
PSMA3 PSMD4 5
PSMA3 PSMD5 3
PSMA3 PSMD6 5
PSMA3 PSMD7 4
PSMA3 PSMD8 4
PSMA3 PSME1 3
PSMA3 PSME2 3
PSMA3 PSME4 2
PSMA3 RPS27A 1
PSMA3 UBA52 1
PSMA3 UBB 1
PSMA3 UBC 2
PSMA4 PSMA5 6
PSMA4 PSMA6 6
PSMA4 PSMA7 6
PSMA4 PSMA8 2
PSMA4 PSMB1 6
PSMA4 PSMB10 2
PSMA4 PSMB2 6
PSMA4 PSMB3 6
PSMA4 PSMB4 6
PSMA4 PSMB5 6
PSMA4 PSMB6 6
PSMA4 PSMB7 6
PSMA4 PSMB8 3
PSMA4 PSMB9 3
PSMA4 PSMC1 3
PSMA4 PSMC2 4
PSMA4 PSMC3 3
PSMA4 PSMC4 3
PSMA4 PSMC5 3
PSMA4 PSMC6 3
PSMA4 PSMD1 3
PSMA4 PSMD11 3
PSMA4 PSMD12 3
PSMA4 PSMD13 3
PSMA4 PSMD14 3
PSMA4 PSMD2 3
PSMA4 PSMD3 4
PSMA4 PSMD4 3
PSMA4 PSMD5 3
PSMA4 PSMD6 3
PSMA4 PSMD7 5
PSMA4 PSMD8 3
PSMA4 PSME1 3
PSMA4 PSME2 3
PSMA4 PSME3 3
PSMA4 PSME4 2
PSMA4 RPS27A 2
PSMA4 UBA52 1
PSMA4 UBB 1
PSMA4 UBC 1
PSMA5 PSMA6 6
PSMA5 PSMA7 6
PSMA5 PSMA8 2
PSMA5 PSMB1 6
PSMA5 PSMB10 2
PSMA5 PSMB2 6
PSMA5 PSMB3 6
PSMA5 PSMB4 6
PSMA5 PSMB5 6
PSMA5 PSMB6 6
PSMA5 PSMB7 6
PSMA5 PSMB8 3
PSMA5 PSMB9 3
PSMA5 PSMC1 4
PSMA5 PSMC2 4
PSMA5 PSMC3 4
PSMA5 PSMC4 4
PSMA5 PSMC5 4
PSMA5 PSMC6 4
PSMA5 PSMD1 4
PSMA5 PSMD11 4
PSMA5 PSMD12 4
PSMA5 PSMD13 4
PSMA5 PSMD14 4
PSMA5 PSMD2 4
PSMA5 PSMD3 4
PSMA5 PSMD4 4
PSMA5 PSMD6 5
PSMA5 PSMD7 3
PSMA5 PSMD8 4
PSMA5 PSME2 3
PSMA5 PSME3 3
PSMA5 PSME4 2
PSMA5 RPS27A 1
PSMA5 UBA52 1
PSMA5 UBB 1
PSMA5 UBC 2
PSMA6 PSMA7 6
PSMA6 PSMA8 2
PSMA6 PSMB1 6
PSMA6 PSMB10 2
PSMA6 PSMB2 6
PSMA6 PSMB3 6
PSMA6 PSMB4 6
PSMA6 PSMB5 6
PSMA6 PSMB6 6
PSMA6 PSMB7 6
PSMA6 PSMB8 3
PSMA6 PSMB9 3
PSMA6 PSMC1 4
PSMA6 PSMC2 5
PSMA6 PSMC3 4
PSMA6 PSMC4 4
PSMA6 PSMC5 4
PSMA6 PSMC6 4
PSMA6 PSMD1 4
PSMA6 PSMD11 4
PSMA6 PSMD12 4
PSMA6 PSMD13 5
PSMA6 PSMD14 3
PSMA6 PSMD2 4
PSMA6 PSMD3 5
PSMA6 PSMD4 5
PSMA6 PSMD5 3
PSMA6 PSMD6 5
PSMA6 PSMD7 5
PSMA6 PSMD8 4
PSMA6 PSME1 3
PSMA6 PSME2 3
PSMA6 PSME3 3
PSMA6 RPS27A 2
PSMA6 UBA52 1
PSMA6 UBB 1
PSMA6 UBC 2
PSMA7 PSMA8 2
PSMA7 PSMB1 6
PSMA7 PSMB10 2
PSMA7 PSMB2 6
PSMA7 PSMB3 6
PSMA7 PSMB4 6
PSMA7 PSMB5 6
PSMA7 PSMB6 6
PSMA7 PSMB7 6
PSMA7 PSMB8 4
PSMA7 PSMB9 3
PSMA7 PSMC1 5
PSMA7 PSMC2 5
PSMA7 PSMC3 5
PSMA7 PSMC4 5
PSMA7 PSMC5 5
PSMA7 PSMC6 4
PSMA7 PSMD1 5
PSMA7 PSMD10 4
PSMA7 PSMD11 5
PSMA7 PSMD12 5
PSMA7 PSMD13 5
PSMA7 PSMD14 4
PSMA7 PSMD2 5
PSMA7 PSMD3 5
PSMA7 PSMD4 4
PSMA7 PSMD5 4
PSMA7 PSMD6 5
PSMA7 PSMD7 4
PSMA7 PSMD8 4
PSMA7 PSME1 3
PSMA7 PSME3 3
PSMA7 PSME4 2
PSMA7 PSMF1 2
PSMA7 RPS27A 1
PSMA7 UBA52 1
PSMA7 UBB 1
PSMA7 UBC 2
PSMA8 PSMB1 2
PSMA8 PSMB2 2
PSMA8 PSMB3 2
PSMA8 PSMB4 2
PSMA8 PSMB5 2
PSMA8 PSMB6 2
PSMA8 PSMB7 2
PSMA8 PSMB8 2
PSMA8 PSMB9 2
PSMA8 PSMC1 2
PSMA8 PSMC2 2
PSMA8 PSMC3 2
PSMA8 PSMC4 2
PSMA8 PSMC5 2
PSMA8 PSMC6 2
PSMA8 PSMD1 2
PSMA8 PSMD13 2
PSMA8 PSMD14 2
PSMA8 PSMD2 2
PSMA8 PSMD3 2
PSMA8 PSMD6 2
PSMA8 PSMD7 2
PSMA8 PSMD8 2
PSMA8 PSME3 2
PSMA8 RPS27A 1
PSMA8 UBA52 1
PSMA8 UBB 1
PSMA8 UBC 1
PSMB10 PSMB2 2
PSMB10 PSMB3 4
PSMB10 PSMB4 3
PSMB10 PSMB5 2
PSMB10 PSMB6 3
PSMB10 PSMB7 3
PSMB10 PSMB8 3
PSMB10 PSMB9 3
PSMB10 PSMD4 2
PSMB10 PSMD5 3
PSMB10 PSMD6 2
PSMB10 PSME1 2
PSMB10 PSME2 2
PSMB10 RPS27A 1
PSMB10 UBA52 1
PSMB10 UBB 1
PSMB10 UBC 1
PSMB11 RPS27A 1
PSMB11 UBA52 1
PSMB11 UBB 1
PSMB11 UBC 1
PSMB1 PSMB10 3
PSMB1 PSMB2 6
PSMB1 PSMB3 6
PSMB1 PSMB4 6
PSMB1 PSMB5 6
PSMB1 PSMB6 6
PSMB1 PSMB7 6
PSMB1 PSMB8 4
PSMB1 PSMB9 3
PSMB1 PSMC1 5
PSMB1 PSMC2 5
PSMB1 PSMC3 4
PSMB1 PSMC4 4
PSMB1 PSMC5 4
PSMB1 PSMC6 4
PSMB1 PSMD1 4
PSMB1 PSMD11 4
PSMB1 PSMD12 4
PSMB1 PSMD13 4
PSMB1 PSMD14 3