Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0001400 mTOR signaling pathway PID Homo sapiens 66 641
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
AKT1S1 ENSG00000204673 84335 Cytoplasm 0.009433962 53.0 15.26666 0.121190131
BNIP3 ENSG00000176171 664 Cytoplasm 0.005813953 2.0 0.0 0.0
BRAF ENSG00000157764 673 Cytoplasm 0.008849558 197.0 11.58302 0.007717808
CYCS ENSG00000172115 54205 Cytoplasm 0.0078125 7.0 1.248496 0.523809524
EEF2K ENSG00000103319 29904 Cytoplasm 0.0078125 14.0 8.972044 0.043956044
EIF4B ENSG00000063046 1975 Cytoplasm 0.007751938 21.0 8.766104 0.061904762
IRS1 ENSG00000169047 3667 Cytoplasm 0.008928571 53.0 6.109353 0.087082729
KRAS ENSG00000133703 3845 Cytoplasm 0.009345794 115.0 7.573417 0.029595728
MAP2K1 ENSG00000169032 5604 Cytoplasm 0.008474576 189.0 4.454125 0.007429922
MLST8 ENSG00000167965 64223 Cytoplasm 0.011235955 74.0 87.95047 0.115883006
RRAGB ENSG00000083750 10325 Cytoplasm 0.00877193 36.0 3.374445 0.182539683
SFN ENSG00000175793 2810 Cytoplasm 0.009708738 50.0 10.73347 0.206530612
TSC1 ENSG00000165699 7248 Cytoplasm 0.009615385 49.0 12.73947 0.162414966
ULK1 ENSG00000177169 8408 Cytoplasm 0.007575758 34.0 0.04819277 0.078431373
ULK2 ENSG00000083290 9706 Cytoplasm 0.007874016 11.0 2.035484 0.363636364
YWHAB ENSG00000166913 7529 Cytoplasm 0.010989011 75.0 58.49122 0.134774775
YWHAZ ENSG00000164924 7534 Cytoplasm 0.01010101 66.0 44.9217 0.12960373
BTRC ENSG00000166167 8945 Cytoplasm/Nucleus 0.008196721 15.0 13.44104 0.323809524
CDK2 ENSG00000123374 1017 Cytoplasm/Nucleus 0.008403361 38.0 29.5005 0.07254623
EEF2 ENSG00000167658 1938 Cytoplasm/Nucleus 0.007246377 13.0 4.933696 0.115384615
EIF4A1 ENSG00000161960 1973 Cytoplasm/Nucleus 0.007692308 15.0 7.043685 0.085714286
EIF4E ENSG00000151247 1977 Cytoplasm/Nucleus 0.00877193 24.0 11.04105 0.293478261
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 0.008695652 51.0 3.25041 0.072156863
FBXW11 ENSG00000072803 23291 Cytoplasm/Nucleus 0.008 13.0 4.888107 0.307692308
IKBKB ENSG00000104365 3551 Cytoplasm/Nucleus 0.008547009 43.0 13.13266 0.067552602
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 0.008333333 190.0 1.187819 0.007073239
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 0.00990099 203.0 72.06711 0.011364191
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 0.00990099 188.0 63.02923 0.012970759
MAPKAP1 ENSG00000119487 79109 Cytoplasm/Nucleus 0.008474576 30.0 2.083196 0.167816092
PDCD4 ENSG00000150593 27250 Cytoplasm/Nucleus 0.007692308 12.0 3.192504 0.151515152
PRKCA ENSG00000154229 5578 Cytoplasm/Nucleus 0.009433962 71.0 31.82552 0.072434608
RB1CC1 ENSG00000023287 9821 Cytoplasm/Nucleus 0.008196721 19.0 4.127141 0.30994152
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 0.009615385 84.0 110.7825 0.038726334
RRAGA ENSG00000155876 10670 Cytoplasm/Nucleus 0.008849558 36.0 4.287424 0.193650794
RRAGC ENSG00000116954 64121 Cytoplasm/Nucleus 0.009090909 39.0 6.696878 0.191632928
RRAGD ENSG00000025039 58528 Cytoplasm/Nucleus 0.008849558 36.0 3.073646 0.20952381
SGK1 ENSG00000118515 6446 Cytoplasm/Nucleus 0.00862069 32.0 4.430105 0.135080645
YWHAE ENSG00000108953 7531 Cytoplasm/Nucleus 0.010309278 61.0 38.29438 0.161748634
YWHAG ENSG00000170027 7532 Cytoplasm/Nucleus 0.009803922 57.0 16.69366 0.164160401
YWHAH ENSG00000128245 7533 Cytoplasm/Nucleus 0.009708738 53.0 11.10744 0.187227866
YWHAQ ENSG00000134308 10971 Cytoplasm/Nucleus 0.01 59.0 31.48673 0.156049094
RICTOR ENSG00000164327 253260 Cytoskeleton/Nucleus 0.00877193 37.0 4.745664 0.157657658
AKT1 ENSG00000142208 207 Membrane 0.011627907 158.0 167.3444 0.033943401
HRAS ENSG00000174775 3265 Membrane 0.00952381 123.0 10.45588 0.026922564
MTOR ENSG00000198793 2475 Membrane 0.012195122 156.0 300.8074 0.032009926
NRAS ENSG00000213281 4893 Membrane 0.009345794 111.0 18.95941 0.030794431
PLD2 ENSG00000129219 5338 Membrane 0.008403361 20.0 1.358878 0.336842105
RAF1 ENSG00000132155 5894 Membrane 0.009090909 250.0 41.46739 0.004947791
RHEB ENSG00000106615 6009 Membrane 0.009259259 49.0 76.96438 0.12670068
ATG13 ENSG00000175224 9776 Unknown 0.007633588 19.0 0.8993309 0.280701754
CLIP1 ENSG00000130779 6249 Unknown 0.007042254 9.0 0.0 0.083333333
DDIT4 ENSG00000168209 54541 Unknown 0.007633588 19.0 1.037423 0.192982456
DEPTOR ENSG00000155792 64798 Unknown 0.01 46.0 35.32154 0.214492754
PDPK1 ENSG00000140992 5170 Unknown 0.008695652 50.0 6.816152 0.055510204
PLD1 ENSG00000075651 5337 Unknown 0.008130081 16.0 0.6445013 0.441666667
PML ENSG00000140464 5371 Unknown 0.008474576 21.0 2.619163 0.238095238
PRR5 ENSG00000186654 55615 Unknown 0.008130081 19.0 0.660768 0.304093567
RPTOR ENSG00000141564 57521 Unknown 0.011363636 87.0 116.3466 0.0879444
SREBF1 ENSG00000072310 6720 Unknown 0.008474576 20.0 9.501599 0.215789474
TSC2 ENSG00000103197 7249 Unknown 0.009708738 63.0 29.96104 0.101382488
CCNE1 ENSG00000105173 898 Nucleus 0.006849315 14.0 2.623229 0.032967033
POLDIP3 ENSG00000100227 84271 Nucleus 0.00625 5.0 0.02649007 0.0
PPARGC1A ENSG00000109819 10891 Nucleus 0.007633588 14.0 0.1724806 0.153846154
RPS6KA1 ENSG00000117676 6195 Nucleus 0.008849558 47.0 35.2913 0.053654024
RRN3 ENSG00000085721 54700 Nucleus 0.007692308 19.0 12.94292 0.035087719
YY1 ENSG00000100811 7528 Nucleus 0.008547009 16.0 16.16796 0.325
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
AKT1S1 ENSG00000204673 84335 Cytoplasm 317.0 349.0 1.55E-6 0.00837
BNIP3 ENSG00000176171 664 Cytoplasm 12.0 2.16 1.55E-6 0.212
BRAF ENSG00000157764 673 Cytoplasm 12094.0 42600.0 1.56E-6 4.04E-5
CYCS ENSG00000172115 54205 Cytoplasm 717.0 113000.0 1.55E-6 0.00153
EEF2K ENSG00000103319 29904 Cytoplasm 56.0 93.0 1.54E-6 0.0156
EIF4B ENSG00000063046 1975 Cytoplasm 414.0 5330.0 1.55E-6 0.0237
IRS1 ENSG00000169047 3667 Cytoplasm 4154.0 22000.0 1.56E-6 7.58E-4
KRAS ENSG00000133703 3845 Cytoplasm 15339.0 61700.0 1.56E-6 8.92E-5
MAP2K1 ENSG00000169032 5604 Cytoplasm 23272.0 37700.0 1.56E-6 1.47E-5
MLST8 ENSG00000167965 64223 Cytoplasm 569.0 1650.0 1.55E-6 0.00434
RRAGB ENSG00000083750 10325 Cytoplasm 221.0 108.0 1.54E-6 0.0152
SFN ENSG00000175793 2810 Cytoplasm 1211.0 17900.0 1.56E-6 0.00276
TSC1 ENSG00000165699 7248 Cytoplasm 363.0 187.0 1.55E-6 0.00793
ULK1 ENSG00000177169 8408 Cytoplasm 182.0 7270.0 1.54E-6 0.0263
ULK2 ENSG00000083290 9706 Cytoplasm 21.0 248.0 1.54E-6 0.2
YWHAB ENSG00000166913 7529 Cytoplasm 2012.0 45200.0 1.56E-6 0.00216
YWHAZ ENSG00000164924 7534 Cytoplasm 2468.0 101000.0 1.56E-6 0.00204
BTRC ENSG00000166167 8945 Cytoplasm/Nucleus 2127.0 41400.0 1.56E-6 0.00284
CDK2 ENSG00000123374 1017 Cytoplasm/Nucleus 4222.0 396000.0 1.56E-6 0.00141
EEF2 ENSG00000167658 1938 Cytoplasm/Nucleus 128.0 72500.0 1.55E-6 0.296
EIF4A1 ENSG00000161960 1973 Cytoplasm/Nucleus 481.0 18800.0 1.55E-6 0.0186
EIF4E ENSG00000151247 1977 Cytoplasm/Nucleus 833.0 61900.0 1.55E-6 0.00865
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 1189.0 11000.0 1.55E-6 4.81E-4
FBXW11 ENSG00000072803 23291 Cytoplasm/Nucleus 679.0 25200.0 1.56E-6 0.0103
IKBKB ENSG00000104365 3551 Cytoplasm/Nucleus 10428.0 206000.0 1.56E-6 1.03E-4
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 22859.0 10500.0 1.55E-6 9.5E-6
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 33563.0 1130000.0 1.56E-6 2.83E-5
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 29207.0 850000.0 1.56E-6 3.17E-5
MAPKAP1 ENSG00000119487 79109 Cytoplasm/Nucleus 219.0 18.9 1.55E-6 0.00473
PDCD4 ENSG00000150593 27250 Cytoplasm/Nucleus 17.0 0.874 1.54E-6 0.0735
PRKCA ENSG00000154229 5578 Cytoplasm/Nucleus 10261.0 710000.0 1.56E-6 2.96E-4
RB1CC1 ENSG00000023287 9821 Cytoplasm/Nucleus 94.0 4330.0 1.55E-6 0.101
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 3539.0 54900.0 1.56E-6 3.46E-4
RRAGA ENSG00000155876 10670 Cytoplasm/Nucleus 215.0 23.2 1.54E-6 0.0164
RRAGC ENSG00000116954 64121 Cytoplasm/Nucleus 228.0 64.4 1.55E-6 0.0159
RRAGD ENSG00000025039 58528 Cytoplasm/Nucleus 222.0 19.2 1.54E-6 0.0163
SGK1 ENSG00000118515 6446 Cytoplasm/Nucleus 316.0 20300.0 1.56E-6 0.0231
YWHAE ENSG00000108953 7531 Cytoplasm/Nucleus 2200.0 115000.0 1.56E-6 0.00436
YWHAG ENSG00000170027 7532 Cytoplasm/Nucleus 1984.0 56700.0 1.56E-6 0.00441
YWHAH ENSG00000128245 7533 Cytoplasm/Nucleus 1198.0 5110.0 1.56E-6 0.00344
YWHAQ ENSG00000134308 10971 Cytoplasm/Nucleus 1689.0 22400.0 1.56E-6 0.00291
RICTOR ENSG00000164327 253260 Cytoskeleton/Nucleus 294.0 1250.0 1.55E-6 0.00539
AKT1 ENSG00000142208 207 Membrane 52751.0 2150000.0 1.57E-6 1.74E-5
HRAS ENSG00000174775 3265 Membrane 21752.0 305000.0 1.56E-6 6.79E-5
MTOR ENSG00000198793 2475 Membrane 6209.0 146000.0 1.56E-6 2.1E-4
NRAS ENSG00000213281 4893 Membrane 14710.0 64200.0 1.56E-6 1.13E-4
PLD2 ENSG00000129219 5338 Membrane 723.0 98500.0 1.55E-6 0.00761
RAF1 ENSG00000132155 5894 Membrane 23706.0 140000.0 1.56E-6 1.64E-5
RHEB ENSG00000106615 6009 Membrane 451.0 579.0 1.55E-6 0.00455
ATG13 ENSG00000175224 9776 Unknown 93.0 812.0 1.54E-6 0.0986
CLIP1 ENSG00000130779 6249 Unknown 475.0 1890.0 1.55E-6 0.0456
DDIT4 ENSG00000168209 54541 Unknown 57.0 2.79 1.55E-6 0.0445
DEPTOR ENSG00000155792 64798 Unknown 59.0 13.7 1.55E-6 0.139
PDPK1 ENSG00000140992 5170 Unknown 7752.0 22600.0 1.56E-6 2.91E-4
PLD1 ENSG00000075651 5337 Unknown 622.0 58700.0 1.55E-6 0.00792
PML ENSG00000140464 5371 Unknown 653.0 17600.0 1.56E-6 0.0128
PRR5 ENSG00000186654 55615 Unknown 92.0 0.616 1.54E-6 0.0172
RPTOR ENSG00000141564 57521 Unknown 582.0 2580.0 1.55E-6 0.0051
SREBF1 ENSG00000072310 6720 Unknown 309.0 119000.0 1.55E-6 0.0165
TSC2 ENSG00000103197 7249 Unknown 891.0 1720.0 1.55E-6 0.00219
CCNE1 ENSG00000105173 898 Nucleus 1165.0 18600.0 1.56E-6 0.00595
POLDIP3 ENSG00000100227 84271 Nucleus 210.0 3050.0 1.54E-6 0.099
PPARGC1A ENSG00000109819 10891 Nucleus 604.0 39600.0 1.56E-6 0.01
RPS6KA1 ENSG00000117676 6195 Nucleus 1675.0 7420.0 1.56E-6 6.33E-4
RRN3 ENSG00000085721 54700 Nucleus 117.0 213.0 1.55E-6 0.0753
YY1 ENSG00000100811 7528 Nucleus 362.0 35200.0 1.56E-6 0.11
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
AKT1S1 ENSG00000204673 84335 Cytoplasm 101.0 155.0 1.51883E-4 0.043564356
BNIP3 ENSG00000176171 664 Cytoplasm 7.0 12.2 1.40174E-4 0.285714286
BRAF ENSG00000157764 673 Cytoplasm 1459.0 1480.0 1.61421E-4 9.88143E-4
CYCS ENSG00000172115 54205 Cytoplasm 117.0 85.6 1.39821E-4 0.011788977
EEF2K ENSG00000103319 29904 Cytoplasm 19.0 64.6 1.27551E-4 0.029239766
EIF4B ENSG00000063046 1975 Cytoplasm 21.0 7.99 1.30259E-4 0.061904762
IRS1 ENSG00000169047 3667 Cytoplasm 778.0 2770.0 1.60514E-4 0.005872564
KRAS ENSG00000133703 3845 Cytoplasm 2404.0 6010.0 1.70126E-4 0.001302449
MAP2K1 ENSG00000169032 5604 Cytoplasm 4166.0 11800.0 1.71821E-4 2.38252E-4
MLST8 ENSG00000167965 64223 Cytoplasm 171.0 373.0 1.43968E-4 0.023185415
RRAGB ENSG00000083750 10325 Cytoplasm 36.0 7.97 1.34318E-4 0.182539683
SFN ENSG00000175793 2810 Cytoplasm 529.0 9720.0 1.70736E-4 0.010225125
TSC1 ENSG00000165699 7248 Cytoplasm 74.0 41.6 1.45328E-4 0.077748982
ULK1 ENSG00000177169 8408 Cytoplasm 34.0 0.0482 1.20438E-4 0.078431373
ULK2 ENSG00000083290 9706 Cytoplasm 11.0 13.2 1.32644E-4 0.363636364
YWHAB ENSG00000166913 7529 Cytoplasm 589.0 7460.0 1.74368E-4 0.011434115
YWHAZ ENSG00000164924 7534 Cytoplasm 826.0 26400.0 1.76523E-4 0.008150268
BTRC ENSG00000166167 8945 Cytoplasm/Nucleus 267.0 11200.0 1.65755E-4 0.018867393
CDK2 ENSG00000123374 1017 Cytoplasm/Nucleus 691.0 26600.0 1.75562E-4 0.009689801
EEF2 ENSG00000167658 1938 Cytoplasm/Nucleus 13.0 30.5 1.29082E-4 0.115384615
EIF4A1 ENSG00000161960 1973 Cytoplasm/Nucleus 30.0 184.0 1.42491E-4 0.110344828
EIF4E ENSG00000151247 1977 Cytoplasm/Nucleus 66.0 489.0 1.51791E-4 0.067132867
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 106.0 101.0 1.41985E-4 0.019586703
FBXW11 ENSG00000072803 23291 Cytoplasm/Nucleus 86.0 3420.0 1.55763E-4 0.058002736
IKBKB ENSG00000104365 3551 Cytoplasm/Nucleus 1056.0 22400.0 1.71262E-4 0.002972857
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 2928.0 355.0 1.56666E-4 2.98241E-4
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 5647.0 122000.0 1.91571E-4 4.01908E-4
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 5295.0 94900.0 1.89179E-4 3.9334E-4
MAPKAP1 ENSG00000119487 79109 Cytoplasm/Nucleus 99.0 16.6 1.39802E-4 0.02020202
PDCD4 ENSG00000150593 27250 Cytoplasm/Nucleus 12.0 2.78 1.3587E-4 0.151515152
PRKCA ENSG00000154229 5578 Cytoplasm/Nucleus 1524.0 27000.0 1.76274E-4 0.003369162
RB1CC1 ENSG00000023287 9821 Cytoplasm/Nucleus 19.0 10.3 1.26936E-4 0.309941521
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 558.0 7730.0 1.69722E-4 0.005701306
RRAGA ENSG00000155876 10670 Cytoplasm/Nucleus 36.0 17.7 1.35796E-4 0.193650794
RRAGC ENSG00000116954 64121 Cytoplasm/Nucleus 39.0 22.6 1.35999E-4 0.191632929
RRAGD ENSG00000025039 58528 Cytoplasm/Nucleus 36.0 6.97 1.34336E-4 0.20952381
SGK1 ENSG00000118515 6446 Cytoplasm/Nucleus 127.0 2820.0 1.65207E-4 0.064366954
YWHAE ENSG00000108953 7531 Cytoplasm/Nucleus 665.0 21100.0 1.76647E-4 0.010712021
YWHAG ENSG00000170027 7532 Cytoplasm/Nucleus 533.0 2730.0 1.70126E-4 0.012590106
YWHAH ENSG00000128245 7533 Cytoplasm/Nucleus 493.0 2430.0 1.72712E-4 0.012945464
YWHAQ ENSG00000134308 10971 Cytoplasm/Nucleus 537.0 5080.0 1.73762E-4 0.012938103
RICTOR ENSG00000164327 253260 Cytoskeleton/Nucleus 121.0 55.5 1.46049E-4 0.023966942
AKT1 ENSG00000142208 207 Membrane 9285.0 328000.0 1.9976E-4 2.07281E-4
HRAS ENSG00000174775 3265 Membrane 4283.0 43500.0 1.85185E-4 7.45373E-4
MTOR ENSG00000198793 2475 Membrane 918.0 20200.0 1.72444E-4 0.004549742
NRAS ENSG00000213281 4893 Membrane 2219.0 11100.0 1.7584E-4 0.001738409
PLD2 ENSG00000129219 5338 Membrane 199.0 5990.0 1.52068E-4 0.024364246
RAF1 ENSG00000132155 5894 Membrane 4276.0 9490.0 1.70271E-4 2.22211E-4
RHEB ENSG00000106615 6009 Membrane 49.0 54.5 1.3725E-4 0.12670068
ATG13 ENSG00000175224 9776 Unknown 19.0 0.829 1.20453E-4 0.280701754
CLIP1 ENSG00000130779 6249 Unknown 30.0 93.0 1.35281E-4 0.098850575
DDIT4 ENSG00000168209 54541 Unknown 31.0 10.7 1.468E-4 0.131182796
DEPTOR ENSG00000155792 64798 Unknown 59.0 38.5 1.39997E-4 0.134424313
PDPK1 ENSG00000140992 5170 Unknown 1616.0 3560.0 1.63079E-4 0.001647611
PLD1 ENSG00000075651 5337 Unknown 120.0 1370.0 1.50308E-4 0.040616247
PML ENSG00000140464 5371 Unknown 135.0 1880.0 1.65948E-4 0.061470426
PRR5 ENSG00000186654 55615 Unknown 19.0 0.634 1.35538E-4 0.304093567
RPTOR ENSG00000141564 57521 Unknown 144.0 1060.0 1.57555E-4 0.044483295
SREBF1 ENSG00000072310 6720 Unknown 44.0 392.0 1.40885E-4 0.121564482
TSC2 ENSG00000103197 7249 Unknown 138.0 923.0 1.54583E-4 0.035121126
CCNE1 ENSG00000105173 898 Nucleus 244.0 598.0 1.51515E-4 0.015044188
POLDIP3 ENSG00000100227 84271 Nucleus 5.0 0.00267 1.18526E-4 0.0
PPARGC1A ENSG00000109819 10891 Nucleus 75.0 116.0 1.49768E-4 0.043603604
RPS6KA1 ENSG00000117676 6195 Nucleus 147.0 767.0 1.51722E-4 0.014816886
RRN3 ENSG00000085721 54700 Nucleus 19.0 4.64 1.3282E-4 0.035087719
YY1 ENSG00000100811 7528 Nucleus 165.0 2340.0 1.58755E-4 0.078861789
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
AKT1 AKT1S1 7
AKT1 BRAF 4
AKT1 DEPTOR 1
AKT1 EIF4EBP1 4
AKT1 IKBKB 7
AKT1 IRS1 3
AKT1 MAPKAP1 3
AKT1 MTOR 11
AKT1 PDCD4 1
AKT1 RAF1 6
AKT1 RICTOR 3
AKT1 RPS6KB1 6
AKT1 RPTOR 3
AKT1S1 EIF4EBP1 1
AKT1S1 MTOR 6
AKT1S1 RPS6KB1 1
AKT1S1 RPTOR 5
AKT1S1 YWHAB 4
AKT1S1 YWHAG 2
AKT1S1 YWHAH 2
AKT1S1 YWHAQ 2
AKT1S1 YWHAZ 2
AKT1 SFN 3
AKT1 TSC1 5
AKT1 TSC2 10
AKT1 YWHAE 2
AKT1 YWHAG 2
AKT1 YWHAZ 5
ATG13 MTOR 3
ATG13 RB1CC1 6
ATG13 ULK1 6
ATG13 ULK2 3
BNIP3 RHEB 2
BRAF HRAS 7
BRAF MAP2K1 12
BRAF MAP2K2 11
BRAF MAPK1 6
BRAF MAPK3 6
BRAF NRAS 5
BRAF RAF1 9
BRAF SFN 5
BRAF YWHAB 8
BRAF YWHAE 5
BRAF YWHAG 6
BRAF YWHAH 6
BRAF YWHAQ 6
BRAF YWHAZ 6
BTRC FBXW11 6
CCNE1 CDK2 12
CCNE1 NRAS 1
CCNE1 RRN3 2
CDK2 AKT1 1
CDK2 EEF2 2
CDK2 PML 3
CDK2 RRN3 3
DDIT4 SFN 2
DDIT4 TSC2 2
DDIT4 YWHAB 2
DDIT4 YWHAE 2
DDIT4 YWHAG 2
DDIT4 YWHAH 2
DDIT4 YWHAQ 2
DDIT4 YWHAZ 3
DEPTOR MLST8 3
DEPTOR MTOR 3
DEPTOR RICTOR 3
DEPTOR RPTOR 3
EIF4A1 EIF4E 5
EIF4A1 PDCD4 4
EIF4B EIF4A1 3
EIF4B EIF4E 2
EIF4E EIF4EBP1 9
FBXW11 IKBKB 2
HRAS MAP2K1 4
HRAS MAP2K2 2
HRAS MAPK1 3
HRAS MAPK3 3
HRAS RAF1 14
HRAS SFN 2
HRAS YWHAB 3
HRAS YWHAE 3
HRAS YWHAG 2
HRAS YWHAH 2
HRAS YWHAQ 2
HRAS YWHAZ 2
IKBKB IRS1 4
IKBKB PRKCA 4
IKBKB TSC1 4
IRS1 PDPK1 2
KRAS BRAF 5
KRAS MAPK1 3
KRAS MAPK3 2
KRAS RAF1 10
KRAS SFN 2
KRAS YWHAB 3
KRAS YWHAE 2
KRAS YWHAG 2
KRAS YWHAH 2
KRAS YWHAQ 2
KRAS YWHAZ 2
MAP2K1 AKT1 1
MAP2K1 MAP2K2 7
MAP2K1 MAPK1 13
MAP2K1 MAPK3 12
MAP2K1 NRAS 2
MAP2K1 RAF1 10
MAP2K1 YWHAB 4
MAP2K1 YWHAE 4
MAP2K1 YWHAZ 3
MAP2K2 AKT1 1
MAP2K2 MAPK1 10
MAP2K2 MAPK3 11
MAP2K2 NRAS 2
MAP2K2 RAF1 7
MAP2K2 YWHAB 4
MAPK1 AKT1 2
MAPK1 CDK2 2
MAPK1 IRS1 4
MAPK1 MAPK3 4
MAPK1 PML 2
MAPK1 RAF1 5
MAPK1 RPS6KA1 10
MAPK1 RPS6KB1 5
MAPK1 RPTOR 2
MAPK1 SREBF1 3
MAPK1 TSC2 6
MAPK3 AKT1 1
MAPK3 CDK2 2
MAPK3 EIF4EBP1 1
MAPK3 IRS1 3
MAPK3 PML 2
MAPK3 RAF1 5
MAPK3 RPS6KA1 7
MAPK3 RPS6KB1 2
MAPK3 RPTOR 2
MAPK3 RRN3 1
MAPK3 SREBF1 3
MAPK3 TSC2 4
MAPKAP1 MLST8 5
MAPKAP1 MTOR 6
MAPKAP1 PRKCA 2
MAPKAP1 PRR5 4
MAPKAP1 RICTOR 6
MAPKAP1 SGK1 2
MLST8 AKT1 2
MLST8 CLIP1 1
MLST8 EIF4EBP1 2
MLST8 IRS1 1
MLST8 MTOR 8
MLST8 PPARGC1A 1
MLST8 PRKCA 1
MLST8 PRR5 4
MLST8 RHEB 2
MLST8 RICTOR 6
MLST8 RPS6KB1 2
MLST8 RPTOR 7
MLST8 RRN3 1
MLST8 SGK1 2
MLST8 ULK1 3
MTOR EEF2K 1
MTOR EIF4EBP1 8
MTOR IRS1 2
MTOR PDPK1 3
MTOR PML 2
MTOR PPARGC1A 1
MTOR PRKCA 2
MTOR PRR5 4
MTOR RHEB 6
MTOR RICTOR 9
MTOR RPS6KB1 8
MTOR RPTOR 10
MTOR RRAGB 2
MTOR RRAGC 3
MTOR RRAGD 2
MTOR RRN3 1
MTOR SGK1 4
MTOR ULK1 7
MTOR ULK2 2
MTOR YWHAQ 4
MTOR YWHAZ 3
NRAS MAPK1 3
NRAS MAPK3 3
NRAS RAF1 10
NRAS SFN 2
NRAS YWHAB 3
NRAS YWHAE 2
NRAS YWHAG 2
NRAS YWHAH 2
NRAS YWHAQ 2
NRAS YWHAZ 2
PDPK1 AKT1 8
PDPK1 IKBKB 2
PDPK1 MAP2K1 1
PDPK1 MAP2K2 1
PDPK1 PRKCA 1
PDPK1 RPS6KA1 2
PDPK1 RPS6KB1 6
PDPK1 SGK1 7
PLD1 MTOR 2
PLD1 PRKCA 4
PLD2 MAPK1 1
PLD2 MAPK3 1
PLD2 RPTOR 3
POLDIP3 RPS6KB1 3
PRKCA AKT1 2
PRKCA BRAF 4
PRKCA HRAS 2
PRKCA KRAS 3
PRKCA MAPK1 1
PRKCA MAPK3 1
PRKCA NRAS 1
PRKCA PLD2 3
PRKCA RAF1 7
PRKCA YWHAG 3
PRKCA YWHAZ 3
PRR5 AKT1 2
PRR5 PRKCA 1
PRR5 RICTOR 4
PRR5 SGK1 2
RAF1 SFN 5
RAF1 SGK1 2
RAF1 YWHAB 9
RAF1 YWHAE 7
RAF1 YWHAG 6
RAF1 YWHAH 6
RAF1 YWHAQ 6
RAF1 YWHAZ 9
RB1CC1 ULK1 6
RB1CC1 ULK2 3
RHEB AKT1S1 2
RHEB DEPTOR 1
RHEB EIF4EBP1 1
RHEB RPS6KB1 1
RHEB RPTOR 6
RHEB ULK1 1
RICTOR SGK1 3
RPS6KA1 AKT1 1
RPS6KA1 DEPTOR 1
RPS6KA1 EIF4B 1
RPS6KA1 RPTOR 2
RPS6KA1 TSC1 2
RPS6KA1 TSC2 5
RPS6KB1 DEPTOR 1
RPS6KB1 EEF2K 3
RPS6KB1 EIF4B 5
RPS6KB1 IRS1 4
RPS6KB1 PDCD4 2
RPTOR CLIP1 1
RPTOR RPS6KB1 2
RPTOR RRAGA 3
RPTOR RRAGB 4
RPTOR RRAGC 4
RPTOR RRAGD 3
RPTOR RRN3 1
RPTOR ULK1 4
RPTOR YWHAQ 2
RRAGA AKT1S1 2
RRAGA DEPTOR 1
RRAGA EIF4EBP1 1
RRAGA MLST8 1
RRAGA MTOR 1
RRAGA RPS6KB1 1
RRAGA RRAGC 7
RRAGA RRAGD 5
RRAGA ULK1 1
RRAGB AKT1S1 2
RRAGB DEPTOR 1
RRAGB EIF4EBP1 1
RRAGB MLST8 1
RRAGB RPS6KB1 1
RRAGB RRAGC 6
RRAGB RRAGD 5
RRAGB ULK1 1
RRAGB YWHAB 2
RRAGC AKT1S1 2
RRAGC DEPTOR 1
RRAGC EIF4EBP1 1
RRAGC MLST8 1
RRAGC RPS6KB1 1
RRAGC ULK1 1
RRAGD AKT1S1 2
RRAGD DEPTOR 1
RRAGD EIF4EBP1 1
RRAGD MLST8 1
RRAGD RPS6KB1 1
RRAGD ULK1 1
SFN MAPK1 1
SFN MAPK3 1
SFN TSC2 3
SFN YWHAG 4
SFN YWHAQ 2
SFN YWHAZ 3
SGK1 IKBKB 1
SGK1 MAPK1 1
TSC1 DEPTOR 1
TSC1 MTOR 3
TSC1 RHEB 4
TSC1 TSC2 10
TSC1 YWHAB 5
TSC1 YWHAE 4
TSC1 YWHAG 5
TSC1 YWHAH 3
TSC1 YWHAQ 3
TSC1 YWHAZ 3
TSC2 DEPTOR 1
TSC2 MTOR 3
TSC2 RHEB 4
TSC2 YWHAB 6
TSC2 YWHAE 6
TSC2 YWHAG 6
TSC2 YWHAH 5
TSC2 YWHAQ 6
TSC2 YWHAZ 6
YWHAB EIF4EBP1 1
YWHAB MAPK1 2
YWHAB MAPK3 2
YWHAB RPS6KB1 1
YWHAB YWHAE 5
YWHAB YWHAG 5
YWHAB YWHAH 3
YWHAB YWHAQ 6
YWHAB YWHAZ 4
YWHAE MAPK1 1
YWHAE MAPK3 1
YWHAE YWHAG 6
YWHAE YWHAH 5
YWHAE YWHAQ 5
YWHAE YWHAZ 4
YWHAG MAPK1 1
YWHAG MAPK3 1
YWHAG YWHAH 4
YWHAG YWHAQ 4
YWHAG YWHAZ 3
YWHAH MAPK1 1
YWHAH MAPK3 1
YWHAH YWHAQ 3
YWHAH YWHAZ 4
YWHAQ MAPK1 1
YWHAQ MAPK3 1
YWHAQ YWHAZ 3
YWHAZ MAPK1 1
YWHAZ MAPK3 1
AKT1 EIF4A1 1
AKT1 PLD1 1
AKT1 PLD2 1
AKT1 PML 1
AKT1 RRAGA 1
AKT1 RRAGB 1
AKT1 RRAGC 1
AKT1 RRAGD 1
AKT1S1 DEPTOR 1
AKT1S1 EIF4E 1
AKT1S1 MLST8 3
AKT1S1 PML 1
AKT1S1 SFN 1
AKT1S1 SGK1 1
AKT1S1 YWHAE 1
AKT1 YWHAB 1
AKT1 YWHAH 1
AKT1 YWHAQ 1
ATG13 MLST8 2
ATG13 RHEB 1
ATG13 RPTOR 2
ATG13 RRAGA 1
ATG13 RRAGB 1
ATG13 RRAGC 1
ATG13 RRAGD 1
BRAF RHEB 2
BRAF SGK1 1
BTRC CCNE1 1
BTRC DDIT4 2
BTRC DEPTOR 1
BTRC EEF2K 1
BTRC HRAS 1
BTRC IKBKB 2
BTRC KRAS 1
BTRC MAP2K1 2
BTRC PDCD4 2
BTRC YWHAB 1
BTRC YWHAE 2
BTRC YWHAG 1
CCNE1 MAPK1 1
CDK2 CYCS 1
CDK2 EIF4A1 1
CDK2 YWHAE 1
CDK2 YWHAG 1
CDK2 YWHAH 1
CDK2 YWHAQ 1
CDK2 YWHAZ 1
CLIP1 MTOR 2
DDIT4 PDPK1 2
DEPTOR FBXW11 1
DEPTOR MAPKAP1 1
DEPTOR PML 1
DEPTOR PRR5 1
DEPTOR SFN 1
DEPTOR YWHAB 1
DEPTOR YWHAE 1
DEPTOR YWHAG 1
DEPTOR YWHAH 1
DEPTOR YWHAQ 1
DEPTOR YWHAZ 1
EEF2 EEF2K 2
EEF2 EIF4A1 1
EEF2K FBXW11 2
EEF2K RPS6KA1 3
EEF2 RPS6KA1 1
EEF2 YWHAQ 1
EEF2 YWHAZ 1
EIF4B FBXW11 1
EIF4B SFN 2
EIF4B YWHAE 1
EIF4B YWHAQ 1
EIF4B YWHAZ 1
EIF4EBP1 MAPK1 2
EIF4EBP1 PRKCA 1
EIF4EBP1 RPS6KB1 1
EIF4EBP1 RPTOR 3
EIF4E IRS1 1
EIF4E PML 3
EIF4E PRKCA 1
EIF4E RPS6KB1 2
FBXW11 PDCD4 2
FBXW11 YWHAB 2
FBXW11 YWHAE 2
FBXW11 YWHAG 1
FBXW11 YWHAZ 2
HRAS AKT1 1
HRAS IKBKB 1
HRAS MTOR 1
HRAS PDPK1 1
HRAS RHEB 1
HRAS SGK1 1
IKBKB MTOR 1
IKBKB RICTOR 2
IKBKB RPTOR 1
IKBKB RRAGA 2
IKBKB RRAGC 2
IKBKB TSC2 1
IKBKB YWHAB 1
IRS1 HRAS 2
IRS1 KRAS 1
IRS1 NRAS 1
IRS1 RPTOR 2