Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0001727 Prolactin NetPath Homo sapiens 105 1733
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
BRAF ENSG00000157764 673 Cytoplasm 0.005434783 128.0 3.254002 0.031496063
CTSD ENSG00000117984 1509 Cytoplasm 0.005025126 15.0 1.79207 0.476190476
DNM2 ENSG00000079805 1785 Cytoplasm 0.005291005 25.0 6.670535 0.48
FYN ENSG00000010810 2534 Cytoplasm 0.006329114 150.0 40.82611 0.065682327
GAB2 ENSG00000033327 9846 Cytoplasm 0.006289308 131.0 28.99151 0.086083382
IRS1 ENSG00000169047 3667 Cytoplasm 0.006134969 148.0 32.04137 0.055616841
JAK1 ENSG00000162434 3716 Cytoplasm 0.006369427 185.0 47.28751 0.045240893
MAP2K1 ENSG00000169032 5604 Cytoplasm 0.006024096 234.0 18.33212 0.020322072
PPIA ENSG00000196262 5478 Cytoplasm 0.005050505 10.0 1.873997 0.577777778
PPIB ENSG00000166794 5479 Cytoplasm 0.004854369 9.0 5.043759 0.194444444
PPP2CA ENSG00000113575 5515 Cytoplasm 0.005952381 76.0 34.02528 0.149122807
PRKCD ENSG00000163932 5580 Cytoplasm 0.006329114 110.0 25.09332 0.119766472
PTPN1 ENSG00000196396 5770 Cytoplasm 0.005617978 55.0 3.041644 0.184511785
PTPN11 ENSG00000179295 5781 Cytoplasm 0.00617284 164.0 30.73575 0.051548706
PTPN6 ENSG00000111679 5777 Cytoplasm 0.005882353 82.0 9.96863 0.144534779
SOCS1 ENSG00000185338 8651 Cytoplasm 0.005464481 54.0 2.109223 0.1453529
SOCS2 ENSG00000120833 8835 Cytoplasm 0.005154639 26.0 1.274548 0.255384615
SOS1 ENSG00000115904 6654 Cytoplasm 0.006097561 154.0 9.415367 0.060351413
TEC ENSG00000135605 7006 Cytoplasm 0.005617978 59.0 1.157111 0.234950321
YWHAZ ENSG00000164924 7534 Cytoplasm 0.006024096 74.0 32.72339 0.152165864
AGAP2 ENSG00000135439 116986 Cytoplasm/Nucleus 0.004830918 12.0 0.1139931 0.242424242
BTRC ENSG00000166167 8945 Cytoplasm/Nucleus 0.005376344 42.0 19.01811 0.120789779
CAMLG ENSG00000164615 819 Cytoplasm/Nucleus 0.004385965 3.0 0.2365266 0.0
CBL ENSG00000110395 867 Cytoplasm/Nucleus 0.005952381 125.0 20.31847 0.067225806
CCND1 ENSG00000110092 595 Cytoplasm/Nucleus 0.005434783 65.0 14.12215 0.093269231
CENPJ ENSG00000151849 55835 Cytoplasm/Nucleus 0.004672897 7.0 0.1213742 0.380952381
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 0.004950495 36.0 1.428705 0.068253968
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 0.005464481 83.0 31.91912 0.043197179
EP300 ENSG00000100393 2033 Cytoplasm/Nucleus 0.005780347 73.0 42.19201 0.124429224
ESR1 ENSG00000091831 2099 Cytoplasm/Nucleus 0.006622517 123.0 108.9039 0.082500333
FBXW11 ENSG00000072803 23291 Cytoplasm/Nucleus 0.005154639 25.0 4.262141 0.14
FLNA ENSG00000196924 2316 Cytoplasm/Nucleus 0.005464481 40.0 7.145439 0.214102564
FOS ENSG00000170345 2353 Cytoplasm/Nucleus 0.005555556 75.0 8.061338 0.09045045
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 0.005154639 43.0 1.062598 0.101882614
HLTF ENSG00000071794 6596 Cytoplasm/Nucleus 0.004716981 6.0 0.02417177 0.266666667
HMGN2 ENSG00000198830 3151 Cytoplasm/Nucleus 0.004716981 5.0 0.1312744 0.6
IGBP1 ENSG00000089289 3476 Cytoplasm/Nucleus 0.004587156 7.0 0.4069123 0.380952381
IRS2 ENSG00000185950 8660 Cytoplasm/Nucleus 0.005780347 89.0 16.60139 0.102655771
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 0.007194245 246.0 231.6694 0.036966982
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 0.006802721 157.0 219.5647 0.051608689
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 0.005649718 214.0 5.673006 0.016409986
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 0.007092199 320.0 186.252 0.019670846
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 0.006711409 298.0 169.7307 0.017761508
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 0.004672897 7.0 0.04045988 0.333333333
MAPK7 ENSG00000166484 5598 Cytoplasm/Nucleus 0.005263158 43.0 1.911488 0.143964563
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 0.006134969 116.0 24.61224 0.085007496
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 0.005649718 88.0 8.922601 0.08045977
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 0.006493506 107.0 137.9221 0.099453359
NCK1 ENSG00000158092 4690 Cytoplasm/Nucleus 0.005524862 61.0 6.407515 0.149180328
NEK3 ENSG00000136098 4752 Cytoplasm/Nucleus 0.004329004 4.0 0.03653993 0.5
NFKB1 ENSG00000109320 4790 Cytoplasm/Nucleus 0.005649718 137.0 30.50583 0.033383426
NFKBIA ENSG00000100906 4792 Cytoplasm/Nucleus 0.005235602 132.0 8.671619 0.013879251
NFKBIB ENSG00000104825 4793 Cytoplasm/Nucleus 0.004901961 67.0 1.855586 0.009497965
PIAS3 ENSG00000131788 10401 Cytoplasm/Nucleus 0.005076142 29.0 0.6467766 0.162561576
PRKCB ENSG00000166501 5579 Cytoplasm/Nucleus 0.00617284 91.0 14.78663 0.155311355
RELA ENSG00000173039 5970 Cytoplasm/Nucleus 0.005988024 153.0 95.08835 0.034399725
RPS6 ENSG00000137154 6194 Cytoplasm/Nucleus 0.005076142 24.0 1.13535 0.130434783
RPS6KA2 ENSG00000071242 6196 Cytoplasm/Nucleus 0.005128205 46.0 1.157042 0.092753623
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 0.005649718 100.0 18.81553 0.056565657
SOCS3 ENSG00000184557 9021 Cytoplasm/Nucleus 0.005376344 76.0 4.428185 0.054385965
SOCS7 ENSG00000274211 30837 Cytoplasm/Nucleus 0.005235602 24.0 0.3466467 0.362318841
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 0.007092199 211.0 128.277 0.049785601
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 0.006802721 188.0 119.6007 0.049721242
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 0.007092199 192.0 195.0604 0.052192408
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 0.006896552 171.0 103.7755 0.064396285
THRB ENSG00000151090 7068 Cytoplasm/Nucleus 0.004854369 12.0 0.01328689 0.363636364
TYK2 ENSG00000105397 7297 Cytoplasm/Nucleus 0.005988024 96.0 22.49593 0.094078947
VAV1 ENSG00000141968 7409 Cytoplasm/Nucleus 0.006024096 114.0 42.3666 0.091600683
VAV2 ENSG00000160293 7410 Cytoplasm/Nucleus 0.005747126 85.0 18.18906 0.130252101
YWHAG ENSG00000170027 7532 Cytoplasm/Nucleus 0.005813953 52.0 19.21194 0.267722474
ZAP70 ENSG00000115085 7535 Cytoplasm/Nucleus 0.005555556 68.0 2.728358 0.149253731
AKT1 ENSG00000142208 207 Membrane 0.007042254 450.0 251.2165 0.010690423
CD3E ENSG00000198851 916 Membrane 0.005291005 38.0 1.307021 0.246088193
ERBB2 ENSG00000141736 2064 Membrane 0.00617284 136.0 25.8367 0.072331155
ERBB4 ENSG00000178568 2066 Membrane 0.005714286 76.0 7.979478 0.142807018
ITGB1 ENSG00000150093 3688 Membrane 0.005235602 40.0 4.541067 0.085897436
LYN ENSG00000254087 4067 Membrane 0.006134969 113.0 18.77217 0.093710493
MTOR ENSG00000198793 2475 Membrane 0.005714286 121.0 31.62047 0.048898072
PIK3CA ENSG00000121879 5290 Membrane 0.006329114 214.0 41.05321 0.032381203
PIK3CG ENSG00000105851 5294 Membrane 0.005952381 163.0 11.26644 0.045444217
PIK3R1 ENSG00000145675 5295 Membrane 0.006802721 248.0 125.4468 0.028274781
PIK3R2 ENSG00000105647 5296 Membrane 0.005882353 172.0 11.20556 0.036651707
PLAU ENSG00000122861 5328 Membrane 0.005102041 18.0 16.50749 0.300653595
PRLR ENSG00000113494 5618 Membrane 0.00591716 76.0 122.4057 0.098947368
PXN ENSG00000089159 5829 Membrane 0.005524862 72.0 45.05621 0.08685446
RAF1 ENSG00000132155 5894 Membrane 0.005780347 178.0 49.72083 0.02380499
SHC1 ENSG00000160691 6464 Membrane 0.006493506 188.0 31.33089 0.050176357
SIRPA ENSG00000198053 140885 Membrane 0.004975124 16.0 0.6156378 0.266666667
SLC12A2 ENSG00000064651 6558 Membrane 0.004716981 5.0 0.01512749 0.8
CISH ENSG00000114737 1154 Unknown 0.005 20.0 0.0751488 0.257894737
EGFR ENSG00000146648 1956 Unknown 0.007042254 250.0 196.9838 0.033477912
GRB2 ENSG00000177885 2885 Unknown 0.006711409 271.0 126.8575 0.023588903
GSK3B ENSG00000082701 2932 Unknown 0.005649718 96.0 28.09659 0.054824561
KHDRBS1 ENSG00000121774 10657 Unknown 0.005208333 22.0 4.641577 0.393939394
MAPK14 ENSG00000112062 1432 Unknown 0.00617284 108.0 43.19635 0.092938733
PAK1 ENSG00000149269 5058 Unknown 0.005882353 98.0 29.34459 0.091941931
PIK3CB ENSG00000051382 5291 Unknown 0.005988024 171.0 7.597754 0.04375645
PTK2 ENSG00000169398 5747 Unknown 0.006097561 166.0 40.40795 0.04271632
SH2B1 ENSG00000178188 25970 Unknown 0.005102041 25.0 2.708205 0.193333333
STAT3 ENSG00000168610 6774 Unknown 0.006944444 212.0 106.0509 0.044531879
CREBBP ENSG00000005339 1387 Nucleus 0.005780347 68.0 33.61798 0.13476734
MYB ENSG00000118513 4602 Nucleus 0.005291005 25.0 3.431007 0.303333333
RB1 ENSG00000139687 5925 Nucleus 0.005555556 50.0 17.79671 0.168979592
PRL ENSG00000172179 5617 Secreted 0.004950495 26.0 8.52109 0.083076923
SERPINE1 ENSG00000106366 5054 Secreted 0.004219409 7.0 0.1495651 0.047619048
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
BRAF ENSG00000157764 673 Cytoplasm 12094.0 42600.0 1.56E-6 4.04E-5
CTSD ENSG00000117984 1509 Cytoplasm 92.0 45400.0 1.55E-6 0.0781
DNM2 ENSG00000079805 1785 Cytoplasm 554.0 46300.0 1.56E-6 0.0144
FYN ENSG00000010810 2534 Cytoplasm 9828.0 511000.0 1.56E-6 4.85E-4
GAB2 ENSG00000033327 9846 Cytoplasm 4097.0 11500.0 1.56E-6 0.00119
IRS1 ENSG00000169047 3667 Cytoplasm 4154.0 22000.0 1.56E-6 7.58E-4
JAK1 ENSG00000162434 3716 Cytoplasm 8612.0 95400.0 1.56E-6 2.71E-4
MAP2K1 ENSG00000169032 5604 Cytoplasm 23272.0 37700.0 1.56E-6 1.47E-5
PPIA ENSG00000196262 5478 Cytoplasm 66.0 3320.0 1.55E-6 0.166
PPIB ENSG00000166794 5479 Cytoplasm 226.0 40500.0 1.55E-6 0.0278
PPP2CA ENSG00000113575 5515 Cytoplasm 2845.0 162000.0 1.56E-6 0.00436
PRKCD ENSG00000163932 5580 Cytoplasm 4033.0 210000.0 1.56E-6 0.00131
PTPN1 ENSG00000196396 5770 Cytoplasm 1033.0 23200.0 1.56E-6 0.00642
PTPN11 ENSG00000179295 5781 Cytoplasm 9733.0 167000.0 1.56E-6 2.5E-4
PTPN6 ENSG00000111679 5777 Cytoplasm 3244.0 60000.0 1.56E-6 0.0014
SOCS1 ENSG00000185338 8651 Cytoplasm 1341.0 27000.0 1.56E-6 0.00394
SOCS2 ENSG00000120833 8835 Cytoplasm 265.0 600.0 1.55E-6 0.0365
SOS1 ENSG00000115904 6654 Cytoplasm 23511.0 177000.0 1.56E-6 6.54E-5
TEC ENSG00000135605 7006 Cytoplasm 1137.0 900.0 1.55E-6 0.00547
YWHAZ ENSG00000164924 7534 Cytoplasm 2468.0 101000.0 1.56E-6 0.00204
AGAP2 ENSG00000135439 116986 Cytoplasm/Nucleus 48.0 50.7 1.55E-6 0.0363
BTRC ENSG00000166167 8945 Cytoplasm/Nucleus 2127.0 41400.0 1.56E-6 0.00284
CAMLG ENSG00000164615 819 Cytoplasm/Nucleus 3.0 0.423 1.54E-6 0.0
CBL ENSG00000110395 867 Cytoplasm/Nucleus 5209.0 92900.0 1.56E-6 8.8E-4
CCND1 ENSG00000110092 595 Cytoplasm/Nucleus 2739.0 100000.0 1.56E-6 0.00164
CENPJ ENSG00000151849 55835 Cytoplasm/Nucleus 614.0 3660.0 1.55E-6 0.0291
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 1189.0 11000.0 1.55E-6 4.81E-4
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 3468.0 49000.0 1.56E-6 3.9E-4
EP300 ENSG00000100393 2033 Cytoplasm/Nucleus 6386.0 1380000.0 1.56E-6 0.00143
ESR1 ENSG00000091831 2099 Cytoplasm/Nucleus 1715.0 361000.0 1.56E-6 0.00554
FBXW11 ENSG00000072803 23291 Cytoplasm/Nucleus 679.0 25200.0 1.56E-6 0.0103
FLNA ENSG00000196924 2316 Cytoplasm/Nucleus 709.0 24600.0 1.56E-6 0.0241
FOS ENSG00000170345 2353 Cytoplasm/Nucleus 3623.0 68600.0 1.56E-6 7.3E-4
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 1569.0 45500.0 1.56E-6 0.0022
HLTF ENSG00000071794 6596 Cytoplasm/Nucleus 25.0 0.682 1.55E-6 0.463
HMGN2 ENSG00000198830 3151 Cytoplasm/Nucleus 10.0 0.798 1.55E-6 0.4
IGBP1 ENSG00000089289 3476 Cytoplasm/Nucleus 17.0 5.04 1.55E-6 0.184
IRS2 ENSG00000185950 8660 Cytoplasm/Nucleus 2517.0 13000.0 1.56E-6 0.00167
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 9806.0 203000.0 1.56E-6 2.47E-4
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 12667.0 3720000.0 1.57E-6 4.67E-4
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 22859.0 10500.0 1.55E-6 9.5E-6
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 33563.0 1130000.0 1.56E-6 2.83E-5
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 29207.0 850000.0 1.56E-6 3.17E-5
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 56.0 7.73 1.55E-6 0.0195
MAPK7 ENSG00000166484 5598 Cytoplasm/Nucleus 1164.0 3380.0 1.56E-6 0.00133
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 11158.0 360000.0 1.56E-6 1.42E-4
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 6317.0 61100.0 1.56E-6 1.86E-4
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 4967.0 1640000.0 1.57E-6 0.00195
NCK1 ENSG00000158092 4690 Cytoplasm/Nucleus 2321.0 9060.0 1.56E-6 0.00215
NEK3 ENSG00000136098 4752 Cytoplasm/Nucleus 8.0 0.00849 1.54E-6 0.107
NFKB1 ENSG00000109320 4790 Cytoplasm/Nucleus 11386.0 280000.0 1.56E-6 2.06E-4
NFKBIA ENSG00000100906 4792 Cytoplasm/Nucleus 12604.0 63600.0 1.56E-6 3.76E-5
NFKBIB ENSG00000104825 4793 Cytoplasm/Nucleus 3015.0 7650.0 1.56E-6 2.22E-4
PIAS3 ENSG00000131788 10401 Cytoplasm/Nucleus 462.0 7230.0 1.56E-6 0.00912
PRKCB ENSG00000166501 5579 Cytoplasm/Nucleus 8548.0 260000.0 1.56E-6 3.64E-4
RELA ENSG00000173039 5970 Cytoplasm/Nucleus 11059.0 663000.0 1.57E-6 3.08E-4
RPS6 ENSG00000137154 6194 Cytoplasm/Nucleus 2882.0 391000.0 1.56E-6 0.0031
RPS6KA2 ENSG00000071242 6196 Cytoplasm/Nucleus 938.0 988.0 1.55E-6 0.00119
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 3539.0 54900.0 1.56E-6 3.46E-4
SOCS3 ENSG00000184557 9021 Cytoplasm/Nucleus 2446.0 25700.0 1.56E-6 0.00128
SOCS7 ENSG00000274211 30837 Cytoplasm/Nucleus 152.0 153.0 1.55E-6 0.103
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 14851.0 1350000.0 1.57E-6 2.68E-4
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 9900.0 278000.0 1.56E-6 2.9E-4
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 7688.0 196000.0 1.56E-6 4.69E-4
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 6515.0 71100.0 1.56E-6 5.43E-4
THRB ENSG00000151090 7068 Cytoplasm/Nucleus 43.0 452.0 1.55E-6 0.122
TYK2 ENSG00000105397 7297 Cytoplasm/Nucleus 2515.0 18400.0 1.56E-6 0.00193
VAV1 ENSG00000141968 7409 Cytoplasm/Nucleus 6306.0 48900.0 1.56E-6 6.34E-4
VAV2 ENSG00000160293 7410 Cytoplasm/Nucleus 3851.0 27300.0 1.56E-6 0.00136
YWHAG ENSG00000170027 7532 Cytoplasm/Nucleus 1984.0 56700.0 1.56E-6 0.00441
ZAP70 ENSG00000115085 7535 Cytoplasm/Nucleus 1772.0 11800.0 1.55E-6 0.0023
AKT1 ENSG00000142208 207 Membrane 52751.0 2150000.0 1.57E-6 1.74E-5
CD3E ENSG00000198851 916 Membrane 1169.0 13000.0 1.55E-6 0.00331
ERBB2 ENSG00000141736 2064 Membrane 4475.0 103000.0 1.56E-6 0.00131
ERBB4 ENSG00000178568 2066 Membrane 1982.0 32600.0 1.56E-6 0.00386
ITGB1 ENSG00000150093 3688 Membrane 3891.0 368000.0 1.56E-6 0.00113
LYN ENSG00000254087 4067 Membrane 4810.0 92600.0 1.56E-6 6.64E-4
MTOR ENSG00000198793 2475 Membrane 6209.0 146000.0 1.56E-6 2.1E-4
PIK3CA ENSG00000121879 5290 Membrane 27859.0 414000.0 1.56E-6 5.51E-5
PIK3CG ENSG00000105851 5294 Membrane 13674.0 58900.0 1.56E-6 1.37E-4
PIK3R1 ENSG00000145675 5295 Membrane 31452.0 734000.0 1.56E-6 4.03E-5
PIK3R2 ENSG00000105647 5296 Membrane 17436.0 144000.0 1.56E-6 9.14E-5
PLAU ENSG00000122861 5328 Membrane 359.0 26400.0 1.55E-6 0.00643
PRLR ENSG00000113494 5618 Membrane 675.0 3200.0 1.55E-6 0.0193
PXN ENSG00000089159 5829 Membrane 3210.0 123000.0 1.56E-6 0.00188
RAF1 ENSG00000132155 5894 Membrane 23706.0 140000.0 1.56E-6 1.64E-5
SHC1 ENSG00000160691 6464 Membrane 13549.0 312000.0 1.56E-6 2.6E-4
SIRPA ENSG00000198053 140885 Membrane 81.0 7430.0 1.55E-6 0.025
SLC12A2 ENSG00000064651 6558 Membrane 101.0 37900.0 1.55E-6 0.0228
CISH ENSG00000114737 1154 Unknown 258.0 14.1 1.55E-6 0.0103
EGFR ENSG00000146648 1956 Unknown 12590.0 758000.0 1.56E-6 2.83E-4
GRB2 ENSG00000177885 2885 Unknown 29079.0 822000.0 1.57E-6 5.64E-5
GSK3B ENSG00000082701 2932 Unknown 9387.0 367000.0 1.56E-6 1.84E-4
KHDRBS1 ENSG00000121774 10657 Unknown 135.0 10300.0 1.55E-6 0.0458
MAPK14 ENSG00000112062 1432 Unknown 9287.0 427000.0 1.56E-6 2.57E-4
PAK1 ENSG00000149269 5058 Unknown 5363.0 83300.0 1.56E-6 2.49E-4
PIK3CB ENSG00000051382 5291 Unknown 17496.0 62500.0 1.56E-6 1.07E-4
PTK2 ENSG00000169398 5747 Unknown 9391.0 242000.0 1.56E-6 3.21E-4
SH2B1 ENSG00000178188 25970 Unknown 168.0 78.2 1.55E-6 0.0157
STAT3 ENSG00000168610 6774 Unknown 10644.0 313000.0 1.56E-6 2.82E-4
CREBBP ENSG00000005339 1387 Nucleus 4940.0 1650000.0 1.57E-6 0.00177
MYB ENSG00000118513 4602 Nucleus 201.0 118000.0 1.56E-6 0.0375
RB1 ENSG00000139687 5925 Nucleus 4373.0 218000.0 1.56E-6 0.00126
PRL ENSG00000172179 5617 Secreted 456.0 6690.0 1.55E-6 0.00565
SERPINE1 ENSG00000106366 5054 Secreted 269.0 23500.0 1.55E-6 0.00946
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
BRAF ENSG00000157764 673 Cytoplasm 497.0 222.0 3.15756E-4 0.007042254
CTSD ENSG00000117984 1509 Cytoplasm 15.0 3.72 2.97089E-4 0.476190476
DNM2 ENSG00000079805 1785 Cytoplasm 106.0 131.0 3.04878E-4 0.064510332
FYN ENSG00000010810 2534 Cytoplasm 2122.0 17800.0 3.52361E-4 0.002945279
GAB2 ENSG00000033327 9846 Cytoplasm 1350.0 1890.0 3.42818E-4 0.00488812
IRS1 ENSG00000169047 3667 Cytoplasm 977.0 1620.0 3.21543E-4 0.003848768
JAK1 ENSG00000162434 3716 Cytoplasm 1977.0 3720.0 3.3389E-4 0.001842034
MAP2K1 ENSG00000169032 5604 Cytoplasm 3187.0 2050.0 3.37041E-4 4.41412E-4
PPIA ENSG00000196262 5478 Cytoplasm 10.0 3.77 2.96296E-4 0.577777778
PPIB ENSG00000166794 5479 Cytoplasm 9.0 34.2 2.75406E-4 0.194444444
PPP2CA ENSG00000113575 5515 Cytoplasm 290.0 905.0 3.30688E-4 0.031953228
PRKCD ENSG00000163932 5580 Cytoplasm 1156.0 8710.0 3.47947E-4 0.006321245
PTPN1 ENSG00000196396 5770 Cytoplasm 174.0 145.0 3.21543E-4 0.056474653
PTPN11 ENSG00000179295 5781 Cytoplasm 2112.0 10100.0 3.39674E-4 0.002050048
PTPN6 ENSG00000111679 5777 Cytoplasm 901.0 4090.0 3.27547E-4 0.006188186
SOCS1 ENSG00000185338 8651 Cytoplasm 391.0 73.6 3.12989E-4 0.010833497
SOCS2 ENSG00000120833 8835 Cytoplasm 74.0 3.21 2.75103E-4 0.05701592
SOS1 ENSG00000115904 6654 Cytoplasm 2096.0 5420.0 3.43761E-4 0.002748274
TEC ENSG00000135605 7006 Cytoplasm 453.0 326.0 3.05437E-4 0.0172498
YWHAZ ENSG00000164924 7534 Cytoplasm 645.0 7080.0 3.44234E-4 0.015619433
AGAP2 ENSG00000135439 116986 Cytoplasm/Nucleus 12.0 0.0568 2.68312E-4 0.242424242
BTRC ENSG00000166167 8945 Cytoplasm/Nucleus 234.0 1620.0 3.22789E-4 0.044532482
CAMLG ENSG00000164615 819 Cytoplasm/Nucleus 3.0 0.523 2.40154E-4 0.0
CBL ENSG00000110395 867 Cytoplasm/Nucleus 1491.0 7750.0 3.40484E-4 0.004455368
CCND1 ENSG00000110092 595 Cytoplasm/Nucleus 338.0 1330.0 3.31345E-4 0.022843397
CENPJ ENSG00000151849 55835 Cytoplasm/Nucleus 7.0 0.0376 2.63922E-4 0.380952381
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 409.0 129.0 3.0003E-4 0.001653962
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 705.0 6960.0 3.33111E-4 0.003973243
EP300 ENSG00000100393 2033 Cytoplasm/Nucleus 899.0 24800.0 3.58166E-4 0.010531375
ESR1 ENSG00000091831 2099 Cytoplasm/Nucleus 573.0 7520.0 3.48432E-4 0.021509904
FBXW11 ENSG00000072803 23291 Cytoplasm/Nucleus 123.0 343.0 3.00571E-4 0.100226576
FLNA ENSG00000196924 2316 Cytoplasm/Nucleus 139.0 345.0 3.25415E-4 0.077989782
FOS ENSG00000170345 2353 Cytoplasm/Nucleus 535.0 1300.0 3.35008E-4 0.009821835
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 444.0 510.0 3.20924E-4 0.009405568
HLTF ENSG00000071794 6596 Cytoplasm/Nucleus 6.0 0.00426 2.74952E-4 0.266666667
HMGN2 ENSG00000198830 3151 Cytoplasm/Nucleus 10.0 34.0 2.79408E-4 0.355555556
IGBP1 ENSG00000089289 3476 Cytoplasm/Nucleus 7.0 0.225 2.61643E-4 0.380952381
IRS2 ENSG00000185950 8660 Cytoplasm/Nucleus 750.0 562.0 3.1348E-4 0.005557632
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 2150.0 8240.0 3.40948E-4 0.001800297
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 2377.0 155000.0 4.20345E-4 0.003438182
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 2527.0 815.0 3.1736E-4 4.12959E-4
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 5156.0 48800.0 3.73692E-4 4.73077E-4
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 4741.0 37700.0 3.67107E-4 4.62168E-4
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 15.0 0.0666 2.81532E-4 0.161904762
MAPK7 ENSG00000166484 5598 Cytoplasm/Nucleus 177.0 105.0 3.09502E-4 0.025295326
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 2089.0 19200.0 3.5461E-4 0.001802454
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 858.0 1890.0 3.35683E-4 0.00495304
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 580.0 14900.0 3.57271E-4 0.024197487
NCK1 ENSG00000158092 4690 Cytoplasm/Nucleus 436.0 681.0 3.10559E-4 0.027322577
NEK3 ENSG00000136098 4752 Cytoplasm/Nucleus 4.0 0.00842 2.36407E-4 0.5
NFKB1 ENSG00000109320 4790 Cytoplasm/Nucleus 2165.0 21700.0 3.57654E-4 0.001731034
NFKBIA ENSG00000100906 4792 Cytoplasm/Nucleus 2305.0 6460.0 3.30907E-4 6.34566E-4
NFKBIB ENSG00000104825 4793 Cytoplasm/Nucleus 608.0 1020.0 3.01386E-4 0.00458467
PIAS3 ENSG00000131788 10401 Cytoplasm/Nucleus 157.0 1000.0 3.07692E-4 0.022374653
PRKCB ENSG00000166501 5579 Cytoplasm/Nucleus 787.0 2460.0 3.35683E-4 0.009618773
RELA ENSG00000173039 5970 Cytoplasm/Nucleus 2213.0 36200.0 3.66973E-4 0.0021842
RPS6 ENSG00000137154 6194 Cytoplasm/Nucleus 156.0 106.0 3.0175E-4 0.009098429
RPS6KA2 ENSG00000071242 6196 Cytoplasm/Nucleus 197.0 83.5 3.05157E-4 0.013415519
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 1061.0 1950.0 3.31016E-4 0.002230007
SOCS3 ENSG00000184557 9021 Cytoplasm/Nucleus 671.0 289.0 3.17662E-4 0.003389906
SOCS7 ENSG00000274211 30837 Cytoplasm/Nucleus 49.0 1.17 3.01205E-4 0.12755102
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 2835.0 62500.0 3.83877E-4 0.002313306
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 2507.0 16000.0 3.53232E-4 0.001538549
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 2173.0 16500.0 3.50263E-4 0.002097566
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 1793.0 5730.0 3.46741E-4 0.002642967
THRB ENSG00000151090 7068 Cytoplasm/Nucleus 12.0 8.64E-4 2.9274E-4 0.363636364
TYK2 ENSG00000105397 7297 Cytoplasm/Nucleus 526.0 497.0 3.24992E-4 0.008198443
VAV1 ENSG00000141968 7409 Cytoplasm/Nucleus 1216.0 3480.0 3.31675E-4 0.005735597
VAV2 ENSG00000160293 7410 Cytoplasm/Nucleus 546.0 1320.0 3.19898E-4 0.02336257
YWHAG ENSG00000170027 7532 Cytoplasm/Nucleus 130.0 178.0 3.2144E-4 0.118902803
ZAP70 ENSG00000115085 7535 Cytoplasm/Nucleus 360.0 1190.0 3.06843E-4 0.026802847
AKT1 ENSG00000142208 207 Membrane 8322.0 100000.0 3.86847E-4 2.77642E-4
CD3E ENSG00000198851 916 Membrane 135.0 99.5 3.06749E-4 0.09541183
ERBB2 ENSG00000141736 2064 Membrane 866.0 5030.0 3.43171E-4 0.011042732
ERBB4 ENSG00000178568 2066 Membrane 76.0 4.31 2.9976E-4 0.142807018
ITGB1 ENSG00000150093 3688 Membrane 210.0 526.0 3.15856E-4 0.034267487
LYN ENSG00000254087 4067 Membrane 1447.0 11000.0 3.41297E-4 0.003967765
MTOR ENSG00000198793 2475 Membrane 1205.0 2800.0 3.31675E-4 0.002904564
PIK3CA ENSG00000121879 5290 Membrane 1707.0 3150.0 3.43879E-4 0.003250528
PIK3CG ENSG00000105851 5294 Membrane 1112.0 558.0 3.15259E-4 0.005596423
PIK3R1 ENSG00000145675 5295 Membrane 4346.0 40100.0 3.6914E-4 7.18516E-4
PIK3R2 ENSG00000105647 5296 Membrane 3118.0 8940.0 3.43643E-4 9.38181E-4
PLAU ENSG00000122861 5328 Membrane 18.0 34.6 3.01114E-4 0.300653595
PRLR ENSG00000113494 5618 Membrane 76.0 166.0 2.94898E-4 0.098947368
PXN ENSG00000089159 5829 Membrane 621.0 3670.0 3.32779E-4 0.009947535
RAF1 ENSG00000132155 5894 Membrane 2303.0 6460.0 3.37154E-4 8.26935E-4
SHC1 ENSG00000160691 6464 Membrane 2671.0 17900.0 3.62319E-4 0.002124357
SIRPA ENSG00000198053 140885 Membrane 51.0 11.7 2.85796E-4 0.04627451
SLC12A2 ENSG00000064651 6558 Membrane 5.0 0.00128 2.70563E-4 0.8
CISH ENSG00000114737 1154 Unknown 115.0 9.09 2.82726E-4 0.025019069
EGFR ENSG00000146648 1956 Unknown 1832.0 37600.0 3.6914E-4 0.004551048
GRB2 ENSG00000177885 2885 Unknown 3750.0 44000.0 3.7594E-4 0.001292434
GSK3B ENSG00000082701 2932 Unknown 1641.0 17600.0 3.47584E-4 0.001609667
KHDRBS1 ENSG00000121774 10657 Unknown 118.0 573.0 3.17561E-4 0.057945821
MAPK14 ENSG00000112062 1432 Unknown 2180.0 24100.0 3.54988E-4 0.001492984
PAK1 ENSG00000149269 5058 Unknown 776.0 3800.0 3.32336E-4 0.006508148
PIK3CB ENSG00000051382 5291 Unknown 826.0 373.0 3.12305E-4 0.009335975
PTK2 ENSG00000169398 5747 Unknown 1989.0 11400.0 3.45782E-4 0.00200398
SH2B1 ENSG00000178188 25970 Unknown 73.0 19.8 3.0248E-4 0.054794521
STAT3 ENSG00000168610 6774 Unknown 2751.0 23400.0 3.62582E-4 0.001531741
CREBBP ENSG00000005339 1387 Nucleus 702.0 20500.0 3.5461E-4 0.014618921
MYB ENSG00000118513 4602 Nucleus 25.0 1.27 3.04044E-4 0.303333333
RB1 ENSG00000139687 5925 Nucleus 699.0 11900.0 3.45901E-4 0.009858537
PRL ENSG00000172179 5617 Secreted 26.0 7.07 2.5641E-4 0.083076923
SERPINE1 ENSG00000106366 5054 Secreted 7.0 0.0297 2.63297E-4 0.047619048
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
AGAP2 PIK3CA 1
AGAP2 PIK3R1 3
AKT1 AGAP2 1
AKT1 BRAF 4
AKT1 CREBBP 4
AKT1 EGFR 4
AKT1 EIF4EBP1 4
AKT1 EP300 6
AKT1 ESR1 3
AKT1 FLNA 1
AKT1 FOXO3 11
AKT1 GSK3B 13
AKT1 IRS1 3
AKT1 MTOR 11
AKT1 NFKB1 3
AKT1 PPP2CA 5
AKT1 PTPN1 3
AKT1 RAF1 6
AKT1 RELA 4
AKT1 RPS6KB1 6
AKT1 STAT1 3
AKT1 STAT3 2
AKT1 YWHAG 2
AKT1 YWHAZ 5
BRAF MAP2K1 12
BRAF MAP2K2 11
BRAF MAPK1 6
BRAF MAPK3 6
BRAF RAF1 9
BRAF STAT1 1
BRAF STAT3 1
BRAF STAT5A 1
BRAF STAT5B 1
BRAF YWHAG 6
BRAF YWHAZ 6
BTRC FBXW11 6
BTRC GSK3B 5
BTRC JAK2 1
BTRC NFKB1 5
BTRC NFKBIA 10
BTRC NFKBIB 6
BTRC PRL 1
BTRC PRLR 3
BTRC RELA 5
CBL EGFR 11
CBL ERBB2 3
CBL ERBB4 3
CBL FYN 9
CBL GRB2 10
CBL JAK1 2
CBL JAK2 2
CBL LYN 8
CBL NCK1 3
CBL PIK3CA 5
CBL PIK3CB 4
CBL PIK3CG 2
CBL PIK3R1 9
CBL PIK3R2 7
CBL PTPN11 4
CBL SHC1 7
CBL SOS1 5
CBL SRC 6
CBL TYK2 5
CBL VAV1 7
CBL VAV2 4
CBL YWHAZ 5
CBL ZAP70 7
CCND1 CREBBP 3
CCND1 ESR1 4
CCND1 RB1 10
CD3E CBL 1
CD3E JUN 1
CD3E SHC1 3
CD3E VAV1 1
CD3E ZAP70 8
CENPJ YWHAG 4
CISH JAK1 2
CISH JAK2 2
CISH STAT3 2
CREBBP EP300 5
CREBBP HLTF 2
CREBBP JUN 4
CREBBP MAPK3 2
CREBBP MYB 4
CREBBP MYC 4
CREBBP PIAS3 3
CREBBP PRLR 2
CREBBP RELA 7
CREBBP SRC 3
CREBBP STAT1 6
CREBBP STAT3 7
CREBBP STAT5A 2
CREBBP STAT5B 2
DNM2 CBL 1
DNM2 GRB2 5
EGFR ERBB2 11
EGFR ERBB4 5
EGFR GAB2 3
EGFR GRB2 12
EGFR JAK1 4
EGFR JAK2 3
EGFR LYN 4
EGFR MAPK1 4
EGFR MAPK3 3
EGFR MTOR 2
EGFR NCK1 6
EGFR PIK3CA 4
EGFR PIK3CB 4
EGFR PIK3CG 2
EGFR PIK3R1 8
EGFR PIK3R2 7
EGFR PPP2CA 3
EGFR PRKCB 2
EGFR PRKCD 3
EGFR PTK2 7
EGFR PTPN1 6
EGFR PTPN11 7
EGFR PTPN6 4
EGFR PXN 2
EGFR SHC1 12
EGFR SOS1 9
EGFR SRC 8
EGFR STAT1 7
EGFR STAT3 8
EGFR STAT5A 7
EGFR STAT5B 7
EGFR VAV1 5
EGFR VAV2 7
ELK1 EP300 3
ELK1 FOS 5
EP300 ESR1 6
EP300 FOS 3
EP300 FOXO3 5
EP300 JUN 5
EP300 MYB 4
EP300 MYC 5
EP300 NFKB1 4
EP300 PIAS3 4
EP300 RB1 4
EP300 RELA 7
EP300 STAT1 6
EP300 STAT3 8
EP300 STAT5A 4
EP300 STAT5B 2
ERBB2 AKT1 2
ERBB2 ERBB4 6
ERBB2 ESR1 6
ERBB2 FYN 2
ERBB2 GAB2 3
ERBB2 GRB2 9
ERBB2 JAK1 3
ERBB2 JAK2 4
ERBB2 MAPK1 2
ERBB2 MAPK3 2
ERBB2 MAPK8 1
ERBB2 PIK3CA 4
ERBB2 PIK3CB 3
ERBB2 PIK3CG 3
ERBB2 PIK3R1 7
ERBB2 PIK3R2 4
ERBB2 PTK2 5
ERBB2 PTPN11 5
ERBB2 SHC1 11
ERBB2 SOS1 4
ERBB2 SRC 5
ERBB2 STAT1 3
ERBB2 STAT3 3
ERBB2 TEC 3
ERBB2 VAV1 3
ERBB2 VAV2 3
ERBB4 AKT1 2
ERBB4 FYN 2
ERBB4 GAB2 2
ERBB4 GRB2 8
ERBB4 MAPK1 1
ERBB4 MAPK3 1
ERBB4 PIK3CA 4
ERBB4 PIK3CB 3
ERBB4 PIK3CG 3
ERBB4 PIK3R1 3
ERBB4 PIK3R2 5
ERBB4 PRLR 2
ERBB4 SHC1 8
ERBB4 SOS1 2
ERBB4 STAT5A 7
ERBB4 STAT5B 5
ESR1 BRAF 2
ESR1 FOS 3
ESR1 FOXO3 4
ESR1 GRB2 4
ESR1 IRS1 2
ESR1 JAK2 4
ESR1 JUN 7
ESR1 MAPK1 3
ESR1 MYC 5
ESR1 PIK3CA 2
ESR1 PIK3R1 6
ESR1 RELA 5
ESR1 SHC1 4
ESR1 SOS1 3
ESR1 SRC 7
ESR1 STAT5A 5
FBXW11 GSK3B 2
FBXW11 NFKB1 4
FBXW11 NFKBIA 8
FBXW11 NFKBIB 7
FBXW11 RELA 4
FLNA ITGB1 5
FLNA MAPK8 1
FLNA MAPK9 1
FLNA PTK2 2
FLNA PXN 2
FLNA SRC 3
FOS CCND1 2
FOS JUN 12
FOXO3 YWHAG 2
FOXO3 YWHAZ 5
FYN AGAP2 2
FYN AKT1 2
FYN CD3E 2
FYN EGFR 2
FYN GAB2 3
FYN GRB2 3
FYN IRS1 4
FYN JAK2 3
FYN LYN 4
FYN MAPK14 3
FYN NCK1 3
FYN PAK1 2
FYN PIK3CA 2
FYN PIK3R1 6
FYN PIK3R2 4
FYN PRKCD 4
FYN PTK2 5
FYN PTPN11 5
FYN PXN 5
FYN RAF1 3
FYN SHC1 7
FYN SOS1 4
FYN SRC 5
FYN STAT1 3
FYN STAT3 5
FYN STAT5A 2
FYN STAT5B 2
FYN VAV1 5
FYN VAV2 3
FYN ZAP70 4
GAB2 AKT1 3
GAB2 GRB2 7
GAB2 JAK2 2
GAB2 LYN 4
GAB2 MAPK1 4
GAB2 MAPK3 5
GAB2 PIK3CA 5
GAB2 PIK3CB 5
GAB2 PIK3CG 3
GAB2 PIK3R1 7
GAB2 PIK3R2 4
GAB2 PTPN11 7
GAB2 PTPN6 3
GAB2 SHC1 7
GAB2 SOS1 3
GAB2 SRC 4
GRB2 AKT1 3
GRB2 IRS1 8
GRB2 IRS2 5
GRB2 JAK1 5
GRB2 JAK2 5
GRB2 LYN 3
GRB2 MAP2K1 1
GRB2 MAPK1 2
GRB2 MTOR 1
GRB2 NCK1 2
GRB2 PAK1 4
GRB2 PIK3CA 4
GRB2 PIK3CB 4
GRB2 PIK3CG 3
GRB2 PIK3R1 9
GRB2 PIK3R2 6
GRB2 PRKCD 2
GRB2 PTK2 8
GRB2 PTPN1 4
GRB2 PTPN11 9
GRB2 PTPN6 5
GRB2 PXN 2
GRB2 SH2B1 3
GRB2 SHC1 13
GRB2 SIRPA 2
GRB2 SOCS1 5
GRB2 SOS1 12
GRB2 SRC 5
GRB2 STAT3 1
GRB2 TEC 3
GRB2 VAV1 9
GRB2 VAV2 6
GRB2 YWHAZ 2
GSK3B CCND1 3
GSK3B ESR1 1
GSK3B JUN 5
GSK3B MYC 7
GSK3B PPP2CA 4
GSK3B RELA 2
GSK3B STAT1 1
GSK3B STAT3 1
GSK3B STAT5A 1
GSK3B STAT5B 1
IGBP1 PPP2CA 4
IRS1 CBL 1
IRS1 IRS2 4
IRS1 JAK1 5
IRS1 JAK2 4
IRS1 KHDRBS1 2
IRS1 PIK3CA 7
IRS1 PIK3CB 5
IRS1 PIK3CG 3
IRS1 PIK3R1 11
IRS1 PIK3R2 8
IRS1 PRKCD 3
IRS1 PTPN1 4
IRS1 PTPN11 5
IRS1 PXN 1
IRS1 SH2B1 4
IRS1 SHC1 7
IRS1 SOS1 6
IRS1 TYK2 2
IRS2 JAK1 5
IRS2 JAK2 4
IRS2 PIK3CA 7
IRS2 PIK3CB 4
IRS2 PIK3CG 2
IRS2 PIK3R1 8
IRS2 PIK3R2 5
IRS2 SH2B1 2
IRS2 SHC1 4
IRS2 SOS1 3
IRS2 TYK2 3
ITGB1 EGFR 2
ITGB1 PTK2 6
ITGB1 PXN 7
ITGB1 SRC 3
JAK1 AKT1 4
JAK1 JAK2 4
JAK1 MAPK1 2
JAK1 MAPK3 2
JAK1 PIK3CA 4
JAK1 PIK3CB 3
JAK1 PIK3R1 6
JAK1 PIK3R2 4
JAK1 PTPN11 7
JAK1 SHC1 4
JAK1 SOCS1 7
JAK1 SOCS3 7
JAK1 SOS1 2
JAK1 STAT1 9
JAK1 STAT3 11
JAK1 STAT5A 8
JAK1 STAT5B 7
JAK1 TYK2 4
JAK1 VAV1 1
JAK2 AKT1 2
JAK2 BRAF 1
JAK2 HLTF 1
JAK2 LYN 3
JAK2 MAPK1 3
JAK2 MAPK3 3
JAK2 NFKB1 1
JAK2 NFKBIA 2
JAK2 PAK1 2
JAK2 PIK3CA 4
JAK2 PIK3CB 4
JAK2 PIK3CG 2
JAK2 PIK3R1 8
JAK2 PIK3R2 4
JAK2 PPP2CA 2
JAK2 PRLR 6
JAK2 PTK2 3
JAK2 PTPN1 4
JAK2 PTPN11 6
JAK2 PXN 1
JAK2 RAF1 3
JAK2 RELA 1
JAK2 SH2B1 5
JAK2 SHC1 7
JAK2 SOCS1 8
JAK2 SOCS3 8
JAK2 SOS1 3
JAK2 SRC 4
JAK2 STAT1 11
JAK2 STAT3 11
JAK2 STAT5A 9
JAK2 STAT5B 8
JAK2 TEC 4
JAK2 TYK2 4
JAK2 VAV2 1
JUN CCND1 2
JUN MYC 4
JUN PPP2CA 3
JUN RB1 5
JUN RELA 5
JUN SRC 2
JUN STAT1 3
JUN YWHAZ 2
KHDRBS1 PIK3R1 5
LYN MAPK1 2
LYN MAPK14 1
LYN MAPK3 5
LYN MAPK8 1
LYN PIK3CA 4
LYN PIK3CB 3
LYN PIK3CG 4
LYN PIK3R1 3
LYN PIK3R2 2
LYN PRKCB 3
LYN PRKCD 2
LYN PTK2 6
LYN PTPN6 5
LYN PXN 1