Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0001805 Ras Pathway PANTHER Homo sapiens 69 921
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
BRAF ENSG00000157764 673 Cytoplasm 0.009259259 198.0 6.01 0.01604881
GSK3A ENSG00000105723 2931 Cytoplasm 0.00729927 24.0 0.00685 0.05072464
KRAS ENSG00000133703 3845 Cytoplasm 0.010752688 241.0 69.3 0.01338174
MAP2K1 ENSG00000169032 5604 Cytoplasm 0.01 261.0 17.6 0.01173003
MAPK10 ENSG00000109339 5602 Cytoplasm 0.009345794 104.0 21.7 0.04051531
MAPK13 ENSG00000156711 5603 Cytoplasm 0.009009009 65.0 6.12 0.09423077
PAK2 ENSG00000180370 5062 Cytoplasm 0.00952381 81.0 5.78 0.10401235
PAK3 ENSG00000077264 5063 Cytoplasm 0.008547009 48.0 2.22 0.09929078
RAC1 ENSG00000136238 5879 Cytoplasm 0.010869565 170.0 121.0 0.03090846
RALB ENSG00000144118 5899 Cytoplasm 0.008 20.0 8.48 0.12631579
RALGDS ENSG00000160271 5900 Cytoplasm 0.008196721 34.0 3.41 0.08912656
RHOC ENSG00000155366 389 Cytoplasm 0.007936508 18.0 0.449 0.24836601
SOS1 ENSG00000115904 6654 Cytoplasm 0.009615385 142.0 14.5 0.0303666
SOS2 ENSG00000100485 6655 Cytoplasm 0.008928571 94.0 4.27 0.04438344
ARAF ENSG00000078061 369 Cytoplasm/Nucleus 0.008695652 145.0 2.13 0.01772031
ATF2 ENSG00000115966 1386 Cytoplasm/Nucleus 0.009259259 65.0 11.1 0.09903846
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 0.008928571 94.0 11.7 0.03820636
ETS1 ENSG00000134954 2113 Cytoplasm/Nucleus 0.008064516 24.0 2.07 0.18478261
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 0.010204082 149.0 42.1 0.03518955
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 0.009433962 247.0 7.87 0.01036832
MAP2K3 ENSG00000034152 5606 Cytoplasm/Nucleus 0.009433962 87.0 12.0 0.07190591
MAP2K6 ENSG00000108984 5608 Cytoplasm/Nucleus 0.009345794 78.0 12.2 0.08191808
MAP2K7 ENSG00000076984 5609 Cytoplasm/Nucleus 0.008849558 75.0 3.89 0.07063063
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 0.010416667 258.0 61.0 0.01333213
MAPK11 ENSG00000185386 5600 Cytoplasm/Nucleus 0.009708738 98.0 24.1 0.06122449
MAPK12 ENSG00000188130 6300 Cytoplasm/Nucleus 0.009009009 68.0 5.14 0.09174715
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 0.01 247.0 58.2 0.01158619
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 0.010638298 144.0 66.2 0.04040404
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 0.009615385 120.0 24.6 0.03963585
MAPKAPK2 ENSG00000162889 9261 Cytoplasm/Nucleus 0.008264463 62.0 4.64 0.05023797
MAPKAPK3 ENSG00000114738 7867 Cytoplasm/Nucleus 0.008264463 40.0 0.969 0.11923077
RPS6KA2 ENSG00000071242 6196 Cytoplasm/Nucleus 0.008264463 41.0 0.948 0.1195122
RPS6KA3 ENSG00000177189 6197 Cytoplasm/Nucleus 0.008547009 51.0 7.14 0.09568627
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 0.011111111 128.0 33.4 0.06606791
PIK3CD ENSG00000171608 5293 Cytoskeleton 0.009009009 175.0 7.65 0.01425287
RHOA ENSG00000067560 387 Cytoskeleton/Nucleus 0.009345794 57.0 14.9 0.14348371
AKT1 ENSG00000142208 207 Membrane 0.012658228 336.0 178.0 0.01179815
AKT3 ENSG00000117020 10000 Membrane 0.011904762 273.0 95.6 0.01602564
CDC42 ENSG00000070831 998 Membrane 0.009803922 99.0 39.7 0.04638219
EXOC2 ENSG00000112685 55770 Membrane 0.006711409 10.0 0.961 0.06666667
HRAS ENSG00000174775 3265 Membrane 0.011904762 259.0 117.0 0.01738948
NRAS ENSG00000213281 4893 Membrane 0.011764706 231.0 93.3 0.02013928
PIK3CA ENSG00000121879 5290 Membrane 0.009009009 192.0 11.0 0.01183464
PIK3CG ENSG00000105851 5294 Membrane 0.009090909 183.0 11.9 0.01321083
PLD2 ENSG00000129219 5338 Membrane 0.008196721 22.0 1.95 0.26839827
RAC2 ENSG00000128340 5880 Membrane 0.009433962 91.0 22.3 0.05128205
RAC3 ENSG00000169750 5881 Membrane 0.009090909 77.0 14.4 0.05604921
RAF1 ENSG00000132155 5894 Membrane 0.009345794 243.0 12.3 0.01030507
RALA ENSG00000006451 5898 Membrane 0.008333333 28.0 19.0 0.11640212
RHOB ENSG00000143878 388 Membrane 0.007936508 16.0 0.351 0.31666667
SHC1 ENSG00000160691 6464 Membrane 0.009708738 76.0 5.55 0.12315789
TIAM1 ENSG00000156299 7074 Membrane 0.008264463 36.0 0.688 0.12380952
GSK3B ENSG00000082701 2932 Unknown 0.008196721 75.0 2.05 0.02954955
MAP2K4 ENSG00000065559 6416 Unknown 0.009090909 97.0 5.96 0.05197595
MAP3K1 ENSG00000095015 4214 Unknown 0.01010101 104.0 8.95 0.08103062
MAP3K7CL ENSG00000156265 56911 Unknown 0.007692308 21.0 0.345 0.17142857
MAPK14 ENSG00000112062 1432 Unknown 0.010309278 128.0 42.6 0.05007382
PAK1 ENSG00000149269 5058 Unknown 0.009708738 112.0 10.7 0.05888031
PDPK1 ENSG00000140992 5170 Unknown 0.009174312 123.0 12.2 0.0286552
PIK3C3 ENSG00000078142 5289 Unknown 0.00877193 34.0 6.59 0.28163993
PIK3CB ENSG00000051382 5291 Unknown 0.009174312 178.0 9.19 0.01586999
PLD1 ENSG00000075651 5337 Unknown 0.008130081 17.0 1.42 0.40441176
RGL1 ENSG00000143344 23179 Unknown 0.007462687 7.0 0.0918 0.47619048
RGL2 ENSG00000237441 5863 Unknown 0.007633588 11.0 0.566 0.25454545
RPS6KA6 ENSG00000072133 27330 Unknown 0.008130081 37.0 0.905 0.1036036
STAT3 ENSG00000168610 6774 Unknown 0.011235955 139.0 39.8 0.0571369
MAP3K4 ENSG00000085511 4216 Nucleus 0.008130081 27.0 0.74 0.14814815
RPS6KA1 ENSG00000117676 6195 Nucleus 0.008403361 48.0 1.9 0.10460993
SRF ENSG00000112658 6722 Nucleus 0.008064516 39.0 2.08 0.05937922
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
BRAF ENSG00000157764 673 Cytoplasm 12094.0 42600.0 1.56E-6 4.04E-5
GSK3A ENSG00000105723 2931 Cytoplasm 885.0 2470.0 1.55E-6 0.00129
KRAS ENSG00000133703 3845 Cytoplasm 15339.0 61700.0 1.56E-6 8.92E-5
MAP2K1 ENSG00000169032 5604 Cytoplasm 23272.0 37700.0 1.56E-6 1.47E-5
MAPK10 ENSG00000109339 5602 Cytoplasm 3333.0 15900.0 1.56E-6 3.89E-4
MAPK13 ENSG00000156711 5603 Cytoplasm 1530.0 5010.0 1.55E-6 9.92E-4
PAK2 ENSG00000180370 5062 Cytoplasm 2174.0 15000.0 1.56E-6 0.00109
PAK3 ENSG00000077264 5063 Cytoplasm 711.0 931.0 1.55E-6 0.00287
RAC1 ENSG00000136238 5879 Cytoplasm 14443.0 874000.0 1.56E-6 1.69E-4
RALB ENSG00000144118 5899 Cytoplasm 114.0 85.4 1.55E-6 0.0123
RALGDS ENSG00000160271 5900 Cytoplasm 242.0 81.6 1.55E-6 0.00463
RHOC ENSG00000155366 389 Cytoplasm 434.0 7130.0 1.55E-6 0.0117
SOS1 ENSG00000115904 6654 Cytoplasm 23511.0 177000.0 1.56E-6 6.54E-5
SOS2 ENSG00000100485 6655 Cytoplasm 6309.0 10000.0 1.56E-6 2.71E-4
ARAF ENSG00000078061 369 Cytoplasm/Nucleus 6326.0 11300.0 1.55E-6 1.03E-4
ATF2 ENSG00000115966 1386 Cytoplasm/Nucleus 2727.0 293000.0 1.56E-6 0.00401
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 3468.0 49000.0 1.56E-6 3.9E-4
ETS1 ENSG00000134954 2113 Cytoplasm/Nucleus 716.0 15200.0 1.56E-6 0.00784
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 12667.0 3720000.0 1.57E-6 4.67E-4
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 22859.0 10500.0 1.55E-6 9.5E-6
MAP2K3 ENSG00000034152 5606 Cytoplasm/Nucleus 2871.0 8580.0 1.56E-6 3.52E-4
MAP2K6 ENSG00000108984 5608 Cytoplasm/Nucleus 2682.0 7380.0 1.56E-6 3.98E-4
MAP2K7 ENSG00000076984 5609 Cytoplasm/Nucleus 2839.0 19800.0 1.55E-6 3.25E-4
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 33563.0 1130000.0 1.56E-6 2.83E-5
MAPK11 ENSG00000185386 5600 Cytoplasm/Nucleus 3606.0 96400.0 1.56E-6 9.0E-4
MAPK12 ENSG00000188130 6300 Cytoplasm/Nucleus 1802.0 7750.0 1.56E-6 8.46E-4
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 29207.0 850000.0 1.56E-6 3.17E-5
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 11158.0 360000.0 1.56E-6 1.42E-4
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 6317.0 61100.0 1.56E-6 1.86E-4
MAPKAPK2 ENSG00000162889 9261 Cytoplasm/Nucleus 1421.0 8100.0 1.55E-6 4.69E-4
MAPKAPK3 ENSG00000114738 7867 Cytoplasm/Nucleus 596.0 900.0 1.55E-6 0.017
RPS6KA2 ENSG00000071242 6196 Cytoplasm/Nucleus 938.0 988.0 1.55E-6 0.00119
RPS6KA3 ENSG00000177189 6197 Cytoplasm/Nucleus 1191.0 4530.0 1.56E-6 0.00146
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 9900.0 278000.0 1.56E-6 2.9E-4
PIK3CD ENSG00000171608 5293 Cytoskeleton 14967.0 29900.0 1.56E-6 1.22E-4
RHOA ENSG00000067560 387 Cytoskeleton/Nucleus 5830.0 484000.0 1.56E-6 6.32E-4
AKT1 ENSG00000142208 207 Membrane 52751.0 2150000.0 1.57E-6 1.74E-5
AKT3 ENSG00000117020 10000 Membrane 22158.0 86500.0 1.56E-6 5.25E-5
CDC42 ENSG00000070831 998 Membrane 6876.0 628000.0 1.56E-6 5.19E-4
EXOC2 ENSG00000112685 55770 Membrane 158.0 984.0 1.54E-6 0.0362
HRAS ENSG00000174775 3265 Membrane 21752.0 305000.0 1.56E-6 6.79E-5
NRAS ENSG00000213281 4893 Membrane 14710.0 64200.0 1.56E-6 1.13E-4
PIK3CA ENSG00000121879 5290 Membrane 27859.0 414000.0 1.56E-6 5.51E-5
PIK3CG ENSG00000105851 5294 Membrane 13674.0 58900.0 1.56E-6 1.37E-4
PLD2 ENSG00000129219 5338 Membrane 723.0 98500.0 1.55E-6 0.00761
RAC2 ENSG00000128340 5880 Membrane 2542.0 29900.0 1.55E-6 9.47E-4
RAC3 ENSG00000169750 5881 Membrane 1145.0 11800.0 1.55E-6 0.00217
RAF1 ENSG00000132155 5894 Membrane 23706.0 140000.0 1.56E-6 1.64E-5
RALA ENSG00000006451 5898 Membrane 265.0 3420.0 1.55E-6 0.0137
RHOB ENSG00000143878 388 Membrane 344.0 6860.0 1.55E-6 0.0167
SHC1 ENSG00000160691 6464 Membrane 13549.0 312000.0 1.56E-6 2.6E-4
TIAM1 ENSG00000156299 7074 Membrane 545.0 4270.0 1.55E-6 0.00474
GSK3B ENSG00000082701 2932 Unknown 9387.0 367000.0 1.56E-6 1.84E-4
MAP2K4 ENSG00000065559 6416 Unknown 4071.0 5050.0 1.55E-6 1.59E-4
MAP3K1 ENSG00000095015 4214 Unknown 3556.0 48700.0 1.56E-6 6.01E-4
MAP3K7CL ENSG00000156265 56911 Unknown 136.0 221.0 1.54E-6 0.092
MAPK14 ENSG00000112062 1432 Unknown 9287.0 427000.0 1.56E-6 2.57E-4
PAK1 ENSG00000149269 5058 Unknown 5363.0 83300.0 1.56E-6 2.49E-4
PDPK1 ENSG00000140992 5170 Unknown 7752.0 22600.0 1.56E-6 2.91E-4
PIK3C3 ENSG00000078142 5289 Unknown 1113.0 107000.0 1.56E-6 0.00705
PIK3CB ENSG00000051382 5291 Unknown 17496.0 62500.0 1.56E-6 1.07E-4
PLD1 ENSG00000075651 5337 Unknown 622.0 58700.0 1.55E-6 0.00792
RGL1 ENSG00000143344 23179 Unknown 23.0 166.0 1.55E-6 0.34
RGL2 ENSG00000237441 5863 Unknown 11.0 0.0289 1.54E-6 0.255
RPS6KA6 ENSG00000072133 27330 Unknown 536.0 246.0 1.55E-6 0.00214
STAT3 ENSG00000168610 6774 Unknown 10644.0 313000.0 1.56E-6 2.82E-4
MAP3K4 ENSG00000085511 4216 Nucleus 245.0 185.0 1.55E-6 0.00455
RPS6KA1 ENSG00000117676 6195 Nucleus 1675.0 7420.0 1.56E-6 6.33E-4
SRF ENSG00000112658 6722 Nucleus 617.0 15200.0 1.56E-6 0.00547
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
BRAF ENSG00000157764 673 Cytoplasm 1155.0 3160.0 3.68E-6 0.00140899
GSK3A ENSG00000105723 2931 Cytoplasm 76.0 143.0 3.67E-6 0.039649123
KRAS ENSG00000133703 3845 Cytoplasm 532.0 931.0 3.68E-6 0.007108166
MAP2K1 ENSG00000169032 5604 Cytoplasm 2532.0 3050.0 3.68E-6 5.26177E-4
MAPK10 ENSG00000109339 5602 Cytoplasm 542.0 3680.0 3.68E-6 0.00557939
MAPK13 ENSG00000156711 5603 Cytoplasm 344.0 1950.0 3.68E-6 0.011034646
PAK2 ENSG00000180370 5062 Cytoplasm 372.0 2350.0 3.68E-6 0.012940904
PAK3 ENSG00000077264 5063 Cytoplasm 212.0 927.0 3.68E-6 0.014173299
RAC1 ENSG00000136238 5879 Cytoplasm 1616.0 50800.0 3.69E-6 0.003362658
RALB ENSG00000144118 5899 Cytoplasm 20.0 17.3 3.67E-6 0.12631579
RALGDS ENSG00000160271 5900 Cytoplasm 34.0 6.57 3.67E-6 0.08912656
RHOC ENSG00000155366 389 Cytoplasm 108.0 1470.0 3.68E-6 0.036863967
SOS1 ENSG00000115904 6654 Cytoplasm 1679.0 12500.0 3.68E-6 0.004270662
SOS2 ENSG00000100485 6655 Cytoplasm 814.0 1650.0 3.68E-6 0.010764874
ARAF ENSG00000078061 369 Cytoplasm/Nucleus 1000.0 355.0 3.68E-6 0.001535536
ATF2 ENSG00000115966 1386 Cytoplasm/Nucleus 217.0 2800.0 3.68E-6 0.035202253
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 528.0 9170.0 3.68E-6 0.003126617
ETS1 ENSG00000134954 2113 Cytoplasm/Nucleus 128.0 885.0 3.68E-6 0.037524606
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 1352.0 129000.0 3.69E-6 0.003231225
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 2431.0 1030.0 3.68E-6 3.94425E-4
MAP2K3 ENSG00000034152 5606 Cytoplasm/Nucleus 408.0 689.0 3.68E-6 0.006780845
MAP2K6 ENSG00000108984 5608 Cytoplasm/Nucleus 347.0 406.0 3.67E-6 0.008112475
MAP2K7 ENSG00000076984 5609 Cytoplasm/Nucleus 224.0 69.8 3.67E-6 0.015094491
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 3094.0 76200.0 3.69E-6 8.31788E-4
MAPK11 ENSG00000185386 5600 Cytoplasm/Nucleus 483.0 4470.0 3.68E-6 0.007508398
MAPK12 ENSG00000188130 6300 Cytoplasm/Nucleus 370.0 2070.0 3.68E-6 0.010151615
MAPK3 ENSG00000102882 5595 Cytoplasm/Nucleus 3220.0 74200.0 3.69E-6 7.13929E-4
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 1054.0 26700.0 3.68E-6 0.00386895
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 722.0 13200.0 3.68E-6 0.00376132
MAPKAPK2 ENSG00000162889 9261 Cytoplasm/Nucleus 289.0 198.0 3.67E-6 0.006271626
MAPKAPK3 ENSG00000114738 7867 Cytoplasm/Nucleus 117.0 35.7 3.67E-6 0.018567639
RPS6KA2 ENSG00000071242 6196 Cytoplasm/Nucleus 190.0 21.0 3.67E-6 0.016095795
RPS6KA3 ENSG00000177189 6197 Cytoplasm/Nucleus 208.0 59.1 3.67E-6 0.013377926
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 1011.0 11300.0 3.68E-6 0.007497723
PIK3CD ENSG00000171608 5293 Cytoskeleton 2357.0 6760.0 3.68E-6 0.001671141
RHOA ENSG00000067560 387 Cytoskeleton/Nucleus 403.0 9740.0 3.68E-6 0.027887856
AKT1 ENSG00000142208 207 Membrane 4499.0 99200.0 3.69E-6 6.70472E-4
AKT3 ENSG00000117020 10000 Membrane 3287.0 21500.0 3.69E-6 9.61756E-4
CDC42 ENSG00000070831 998 Membrane 633.0 9510.0 3.68E-6 0.007973884
EXOC2 ENSG00000112685 55770 Membrane 10.0 1.55 3.66E-6 0.066666667
HRAS ENSG00000174775 3265 Membrane 2503.0 11200.0 3.68E-6 0.001519839
NRAS ENSG00000213281 4893 Membrane 2718.0 21100.0 3.68E-6 0.001197052
PIK3CA ENSG00000121879 5290 Membrane 3335.0 42900.0 3.69E-6 0.001244189
PIK3CG ENSG00000105851 5294 Membrane 2434.0 8180.0 3.68E-6 0.001589349
PLD2 ENSG00000129219 5338 Membrane 95.0 208.0 3.68E-6 0.121164614
RAC2 ENSG00000128340 5880 Membrane 628.0 5330.0 3.68E-6 0.006674184
RAC3 ENSG00000169750 5881 Membrane 118.0 6.58 3.67E-6 0.033608576
RAF1 ENSG00000132155 5894 Membrane 2790.0 11100.0 3.68E-6 4.85008E-4
RALA ENSG00000006451 5898 Membrane 28.0 35.7 3.67E-6 0.116402116
RHOB ENSG00000143878 388 Membrane 39.0 157.0 3.67E-6 0.110661269
SHC1 ENSG00000160691 6464 Membrane 1070.0 28500.0 3.68E-6 0.013061382
TIAM1 ENSG00000156299 7074 Membrane 36.0 0.121 3.67E-6 0.123809524
GSK3B ENSG00000082701 2932 Unknown 784.0 38900.0 3.68E-6 0.004264733
MAP2K4 ENSG00000065559 6416 Unknown 615.0 1660.0 3.68E-6 0.003246736
MAP3K1 ENSG00000095015 4214 Unknown 349.0 2450.0 3.68E-6 0.014804203
MAP3K7CL ENSG00000156265 56911 Unknown 130.0 3530.0 3.67E-6 0.100417412
MAPK14 ENSG00000112062 1432 Unknown 921.0 32300.0 3.68E-6 0.004010291
PAK1 ENSG00000149269 5058 Unknown 527.0 6300.0 3.68E-6 0.007950881
PDPK1 ENSG00000140992 5170 Unknown 998.0 857.0 3.68E-6 0.003266312
PIK3C3 ENSG00000078142 5289 Unknown 481.0 630.0 3.68E-6 0.020521483
PIK3CB ENSG00000051382 5291 Unknown 2839.0 16200.0 3.68E-6 0.001498061
PLD1 ENSG00000075651 5337 Unknown 61.0 62.4 3.67E-6 0.22295082
RGL1 ENSG00000143344 23179 Unknown 7.0 0.228 3.66E-6 0.476190476
RGL2 ENSG00000237441 5863 Unknown 11.0 0.444 3.67E-6 0.254545455
RPS6KA6 ENSG00000072133 27330 Unknown 169.0 17.3 3.67E-6 0.013806706
STAT3 ENSG00000168610 6774 Unknown 1132.0 14400.0 3.68E-6 0.006482896
MAP3K4 ENSG00000085511 4216 Nucleus 88.0 62.1 3.67E-6 0.015673981
RPS6KA1 ENSG00000117676 6195 Nucleus 219.0 42.4 3.67E-6 0.012902685
SRF ENSG00000112658 6722 Nucleus 166.0 100.0 3.67E-6 0.008178167
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
AKT1 BRAF 4
AKT1 GSK3A 9
AKT1 GSK3B 13
AKT1 MAP2K4 4
AKT1 RAC1 5
AKT1 RAF1 6
AKT1 STAT1 3
AKT1 STAT3 2
AKT1 TIAM1 1
AKT3 GSK3A 3
AKT3 GSK3B 6
ARAF AKT1 1
ARAF AKT3 1
ARAF BRAF 4
ARAF HRAS 8
ARAF KRAS 4
ARAF MAP2K1 10
ARAF MAP2K2 8
ARAF MAPK1 2
ARAF MAPK3 2
ARAF RAF1 2
ARAF STAT1 1
ARAF STAT3 1
ATF2 JUN 7
ATF2 MAPK10 3
ATF2 STAT3 2
BRAF AKT3 1
BRAF HRAS 7
BRAF MAP2K1 12
BRAF MAP2K2 11
BRAF MAP2K3 2
BRAF MAP2K6 1
BRAF MAPK1 6
BRAF MAPK3 6
BRAF NRAS 5
BRAF RAF1 9
BRAF STAT1 1
BRAF STAT3 1
CDC42 MAP2K3 1
CDC42 MAP3K1 4
CDC42 MAPK10 1
CDC42 MAPK11 3
CDC42 MAPK12 2
CDC42 MAPK14 3
CDC42 MAPK8 3
CDC42 MAPK9 3
CDC42 PAK1 11
CDC42 PAK2 7
CDC42 PAK3 6
CDC42 PLD1 3
CDC42 RAC1 4
CDC42 RAC2 4
CDC42 RAC3 2
CDC42 TIAM1 2
ELK1 SRF 6
EXOC2 RALA 4
GSK3A STAT3 1
GSK3B HRAS 1
GSK3B JUN 5
GSK3B STAT1 1
GSK3B STAT3 1
HRAS JUN 3
HRAS MAP2K1 4
HRAS MAP2K2 2
HRAS MAP3K1 4
HRAS MAPK1 3
HRAS MAPK3 3
HRAS PIK3CA 8
HRAS PIK3CB 4
HRAS PIK3CD 7
HRAS PIK3CG 8
HRAS RAF1 14
HRAS RALA 2
HRAS RALGDS 11
HRAS RGL1 5
HRAS RGL2 4
HRAS SOS1 7
HRAS TIAM1 4
JUN NRAS 2
JUN RHOC 2
JUN STAT1 3
KRAS BRAF 5
KRAS JUN 1
KRAS MAPK1 3
KRAS MAPK3 2
KRAS PIK3CA 5
KRAS PIK3CB 4
KRAS PIK3CD 3
KRAS PIK3CG 5
KRAS RAF1 10
KRAS RALGDS 6
KRAS RGL2 2
KRAS TIAM1 2
MAP2K1 AKT1 1
MAP2K1 AKT3 1
MAP2K1 GSK3B 1
MAP2K1 MAP2K2 7
MAP2K1 MAP3K1 5
MAP2K1 MAPK1 13
MAP2K1 MAPK10 2
MAP2K1 MAPK11 1
MAP2K1 MAPK12 1
MAP2K1 MAPK13 1
MAP2K1 MAPK14 4
MAP2K1 MAPK3 12
MAP2K1 MAPK8 4
MAP2K1 MAPK9 2
MAP2K1 NRAS 2
MAP2K1 PIK3CA 2
MAP2K1 RAF1 10
MAP2K1 STAT1 1
MAP2K1 STAT3 2
MAP2K2 AKT1 1
MAP2K2 AKT3 1
MAP2K2 MAPK1 10
MAP2K2 MAPK10 2
MAP2K2 MAPK11 1
MAP2K2 MAPK12 1
MAP2K2 MAPK13 1
MAP2K2 MAPK14 1
MAP2K2 MAPK3 11
MAP2K2 MAPK8 4
MAP2K2 MAPK9 2
MAP2K2 NRAS 2
MAP2K2 RAF1 7
MAP2K2 STAT1 1
MAP2K2 STAT3 2
MAP2K3 AKT1 1
MAP2K3 AKT3 1
MAP2K3 MAPK1 1
MAP2K3 MAPK10 1
MAP2K3 MAPK11 6
MAP2K3 MAPK12 5
MAP2K3 MAPK13 4
MAP2K3 MAPK14 12
MAP2K3 MAPK3 4
MAP2K3 MAPK8 2
MAP2K3 MAPK9 2
MAP2K3 STAT1 1
MAP2K3 STAT3 1
MAP2K4 AKT3 1
MAP2K4 MAPK10 10
MAP2K4 MAPK11 3
MAP2K4 MAPK12 3
MAP2K4 MAPK13 2
MAP2K4 MAPK14 7
MAP2K4 MAPK8 12
MAP2K4 MAPK9 10
MAP2K4 STAT1 1
MAP2K4 STAT3 1
MAP2K6 AKT1 1
MAP2K6 AKT3 1
MAP2K6 MAPK10 1
MAP2K6 MAPK11 5
MAP2K6 MAPK12 8
MAP2K6 MAPK13 5
MAP2K6 MAPK14 11
MAP2K6 MAPK8 2
MAP2K6 MAPK9 1
MAP2K6 MAPKAPK2 2
MAP2K6 STAT1 1
MAP2K6 STAT3 1
MAP2K7 AKT1 1
MAP2K7 AKT3 1
MAP2K7 MAPK1 2
MAP2K7 MAPK10 6
MAP2K7 MAPK11 1
MAP2K7 MAPK12 1
MAP2K7 MAPK13 1
MAP2K7 MAPK14 2
MAP2K7 MAPK8 12
MAP2K7 MAPK9 10
MAP2K7 STAT1 1
MAP2K7 STAT3 1
MAP3K1 AKT1 1
MAP3K1 AKT3 1
MAP3K1 MAP2K2 2
MAP3K1 MAP2K3 5
MAP3K1 MAP2K4 6
MAP3K1 MAP2K6 4
MAP3K1 MAP2K7 7
MAP3K1 MAPK10 2
MAP3K1 MAPK11 2
MAP3K1 MAPK14 2
MAP3K1 MAPK8 5
MAP3K1 MAPK9 4
MAP3K1 STAT1 1
MAP3K1 STAT3 1
MAP3K4 MAP2K7 1
MAP3K7CL MAP2K3 1
MAP3K7CL MAP2K6 1
MAP3K7CL MAPK10 1
MAP3K7CL MAPK11 1
MAP3K7CL MAPK12 1
MAP3K7CL MAPK13 1
MAP3K7CL MAPK14 1
MAP3K7CL MAPK8 1
MAP3K7CL MAPK9 1
MAPK10 AKT1 1
MAPK10 AKT3 1
MAPK10 ELK1 3
MAPK10 JUN 6
MAPK10 STAT1 2
MAPK10 STAT3 2
MAPK11 AKT1 1
MAPK11 AKT3 1
MAPK11 ATF2 8
MAPK11 ELK1 3
MAPK11 JUN 2
MAPK11 MAPK14 3
MAPK11 MAPKAPK2 8
MAPK11 MAPKAPK3 7
MAPK11 SRF 1
MAPK11 STAT1 2
MAPK11 STAT3 2
MAPK12 AKT1 1
MAPK12 AKT3 1
MAPK12 ATF2 4
MAPK12 ELK1 2
MAPK12 JUN 3
MAPK12 MAPKAPK2 2
MAPK12 MAPKAPK3 2
MAPK12 STAT1 2
MAPK12 STAT3 2
MAPK13 AKT1 1
MAPK13 AKT3 1
MAPK13 ATF2 3
MAPK13 ELK1 2
MAPK13 JUN 2
MAPK13 MAPKAPK2 2
MAPK13 MAPKAPK3 5
MAPK13 STAT1 2
MAPK13 STAT3 2
MAPK14 AKT3 1
MAPK14 ATF2 8
MAPK14 ELK1 5
MAPK14 GSK3B 1
MAPK14 JUN 3
MAPK14 MAPK3 5
MAPK14 MAPKAPK2 11
MAPK14 MAPKAPK3 8
MAPK14 SHC1 2
MAPK14 STAT1 5
MAPK14 STAT3 4
MAPK1 AKT1 2
MAPK1 AKT3 1
MAPK1 ATF2 4
MAPK1 ELK1 9
MAPK1 ETS1 7
MAPK1 MAPK3 4
MAPK1 MAPKAPK2 4
MAPK1 MAPKAPK3 1
MAPK1 RAC1 1
MAPK1 RAF1 5
MAPK1 RPS6KA1 10
MAPK1 RPS6KA2 7
MAPK1 RPS6KA3 9
MAPK1 RPS6KA6 3
MAPK1 SHC1 5
MAPK1 SOS1 5
MAPK1 STAT1 2
MAPK1 STAT3 6
MAPK3 AKT1 1
MAPK3 AKT3 1
MAPK3 ATF2 4
MAPK3 ELK1 8
MAPK3 ETS1 5
MAPK3 GSK3B 1
MAPK3 JUN 4
MAPK3 MAPKAPK2 3
MAPK3 MAPKAPK3 1
MAPK3 RAC1 2
MAPK3 RAF1 5
MAPK3 RPS6KA1 7
MAPK3 RPS6KA2 8
MAPK3 RPS6KA3 8
MAPK3 RPS6KA6 4
MAPK3 SHC1 2
MAPK3 SOS1 2
MAPK3 STAT1 3
MAPK3 STAT3 5
MAPK8 AKT3 1
MAPK8 ATF2 5
MAPK8 ELK1 3
MAPK8 ETS1 1
MAPK8 JUN 9
MAPK8 MAPK9 4
MAPK8 MAPKAPK2 1
MAPK8 RPS6KA1 1
MAPK8 RPS6KA2 1
MAPK8 RPS6KA3 1
MAPK8 RPS6KA6 1
MAPK8 STAT1 2
MAPK8 STAT3 6
MAPK9 AKT1 1
MAPK9 AKT3 1
MAPK9 ATF2 4
MAPK9 JUN 8
MAPK9 STAT1 2
MAPK9 STAT3 4
MAPKAPK2 AKT3 1
MAPKAPK2 SRF 5
MAPKAPK2 STAT1 1
MAPKAPK2 STAT3 3
MAPKAPK3 AKT1 1
MAPKAPK3 AKT3 1
MAPKAPK3 SRF 1
MAPKAPK3 STAT1 1
MAPKAPK3 STAT3 1
NRAS ARAF 3
NRAS MAPK1 3
NRAS MAPK3 3
NRAS PIK3CA 5
NRAS PIK3CB 4
NRAS PIK3CD 3
NRAS PIK3CG 4
NRAS RAF1 10
NRAS RALGDS 4
NRAS RGL2 2
NRAS TIAM1 2
PAK1 AKT3 1
PAK1 BRAF 1
PAK1 JUN 1
PAK1 MAP2K1 4
PAK1 MAP2K2 1
PAK1 MAP2K3 1
PAK1 MAP2K4 3
PAK1 MAP2K6 1
PAK1 MAP3K1 2
PAK1 MAPK10 1
PAK1 MAPK11 2
PAK1 MAPK14 3
PAK1 MAPK8 3
PAK1 MAPK9 1
PAK1 RAC1 9
PAK1 RAF1 8
PAK1 SHC1 2
PAK1 STAT1 1
PAK1 STAT3 1
PAK2 AKT1 1
PAK2 AKT3 1
PAK2 JUN 1
PAK2 MAP3K1 2
PAK2 MAPK10 1
PAK2 MAPK11 2
PAK2 MAPK14 2
PAK2 MAPK8 1
PAK2 MAPK9 1
PAK2 RAC1 6
PAK2 RAF1 5
PAK2 STAT1 2
PAK2 STAT3 1
PAK3 MAPK10 1
PAK3 MAPK11 1
PAK3 MAPK14 1
PAK3 MAPK8 1
PAK3 MAPK9 1
PAK3 RAC1 5
PAK3 RAF1 3
PDPK1 AKT1 8
PDPK1 AKT3 6
PDPK1 MAP2K1 1
PDPK1 MAP2K2 1
PDPK1 PAK1 1
PDPK1 RALGDS 2
PDPK1 RPS6KA1 2
PDPK1 RPS6KA2 1
PDPK1 RPS6KA3 5
PDPK1 RPS6KA6 1
PDPK1 STAT1 1
PDPK1 STAT3 1
PIK3C3 AKT1 1
PIK3C3 AKT3 1
PIK3C3 PIK3CG 3
PIK3C3 SOS1 1
PIK3C3 SOS2 1
PIK3CA AKT1 5
PIK3CA AKT3 4
PIK3CA CDC42 3
PIK3CA PDPK1 4
PIK3CA PIK3CD 2
PIK3CA RAC1 4
PIK3CA RAC2 3
PIK3CA RAC3 2
PIK3CA RHOA 2
PIK3CA SHC1 3
PIK3CA SOS1 3
PIK3CA SOS2 1
PIK3CA STAT1 2
PIK3CA STAT3 3
PIK3CB AKT1 4
PIK3CB AKT3 4
PIK3CB CDC42 2
PIK3CB PDPK1 4
PIK3CB PIK3CA 2
PIK3CB PIK3CD 2
PIK3CB PIK3CG 2
PIK3CB RAC1 4
PIK3CB RAC2 2
PIK3CB RAC3 2
PIK3CB SHC1 3
PIK3CB SOS1 3
PIK3CB SOS2 1
PIK3CB STAT3 2
PIK3CB TIAM1 2
PIK3CD AKT1 3
PIK3CD AKT3 4
PIK3CD CDC42 2
PIK3CD PDPK1 3
PIK3CD PIK3CG 3
PIK3CD RAC1 3
PIK3CD RAC2 2
PIK3CD RAC3 2
PIK3CD SHC1 2
PIK3CD SOS1 2
PIK3CD SOS2 1
PIK3CD STAT3 2
PIK3CG AKT1 5
PIK3CG AKT3 4
PIK3CG CDC42 2
PIK3CG MAP2K1 1
PIK3CG PDPK1 4
PIK3CG PIK3CA 2
PIK3CG RAC1 4
PIK3CG RAC2 2
PIK3CG RAC3 2
PIK3CG SHC1 3
PIK3CG SOS1 3
PIK3CG SOS2 1
PIK3CG STAT3 2
PLD2 MAPK1 1
PLD2 MAPK3 1
RAC1 EXOC2 1
RAC1 MAP2K4 3
RAC1 MAP2K7 2
RAC1 MAP3K1 4
RAC1 MAPK10 3
RAC1 MAPK11 2
RAC1 MAPK14 2
RAC1 MAPK8 5