Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0002040 Signaling events mediated by TCPTP PID Homo sapiens 40 361
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
EIF2A ENSG00000144895 83939 Cytoplasm 0.01162791 6.0 0.0 0.06666667
GAB1 ENSG00000109458 2549 Cytoplasm 0.01923077 90.0 2.178177 0.0576779
JAK1 ENSG00000162434 3716 Cytoplasm 0.01923077 95.0 5.100523 0.04770437
JAK3 ENSG00000105639 3718 Cytoplasm 0.01666667 64.0 0.7229741 0.05505952
LMAN1 ENSG00000074695 3998 Cytoplasm 0.01204819 3.0 0.0 0.0
PTPN1 ENSG00000196396 5770 Cytoplasm 0.01818182 58.0 18.97226 0.09013914
SOS1 ENSG00000115904 6654 Cytoplasm 0.02040816 101.0 3.807335 0.05267327
EIF2AK2 ENSG00000055332 5610 Cytoplasm/Nucleus 0.01449275 12.0 3.04975 0.24242424
KPNA2 ENSG00000182481 3838 Cytoplasm/Nucleus 0.01408451 8.0 0.4550254 0.32142857
KPNB1 ENSG00000108424 3837 Cytoplasm/Nucleus 0.01428571 12.0 0.6293415 0.24242424
PIAS1 ENSG00000033800 8554 Cytoplasm/Nucleus 0.01449275 23.0 0.09944603 0.13043478
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 0.02272727 118.0 39.75754 0.04215558
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 0.02 87.0 50.38046 0.0553328
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 0.01886792 74.0 6.058873 0.07404665
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 0.01886792 68.0 5.547826 0.08779631
STAT6 ENSG00000166888 6778 Cytoplasm/Nucleus 0.01851852 58.0 4.520718 0.1107078
CSF1R ENSG00000182578 1436 Membrane 0.01428571 15.0 2.715903 0.2
INSR ENSG00000171105 3643 Membrane 0.01724138 65.0 5.461599 0.05913462
ITGA1 ENSG00000213949 3672 Membrane 0.01449275 12.0 0.008752735 0.40909091
ITGB1 ENSG00000150093 3688 Membrane 0.01470588 16.0 0.1801256 0.25833333
KDR ENSG00000128052 3791 Membrane 0.01923077 65.0 13.7021 0.09326923
MET ENSG00000105976 4233 Membrane 0.01851852 71.0 7.500374 0.07364185
PDGFRB ENSG00000113721 5159 Membrane 0.01960784 105.0 8.53078 0.04194139
PIK3CA ENSG00000121879 5290 Membrane 0.01960784 90.0 11.93106 0.06017478
PIK3R1 ENSG00000145675 5295 Membrane 0.01851852 97.0 6.442604 0.04467354
SHC1 ENSG00000160691 6464 Membrane 0.0212766 119.0 13.66251 0.03988036
EGFR ENSG00000146648 1956 Unknown 0.02083333 164.0 49.32514 0.01735747
GRB2 ENSG00000177885 2885 Unknown 0.01886792 161.0 12.29175 0.01513975
PIK3CB ENSG00000051382 5291 Unknown 0.01851852 74.0 1.047324 0.07848945
PTPN2 ENSG00000175354 5771 Unknown 0.02173913 81.0 95.84521 0.06574074
STAT3 ENSG00000168610 6774 Unknown 0.0212766 102.0 25.38474 0.05299942
ATR ENSG00000175054 545 Nucleus 0.0125 3.0 0.002188184 0.66666667
CREBBP ENSG00000005339 1387 Nucleus 0.01492537 28.0 1.772099 0.1005291
CSF1 ENSG00000184371 1435 Secreted 0.01351351 11.0 0.2174229 0.07272727
EGF ENSG00000138798 1950 Secreted 0.01818182 61.0 2.125359 0.09071038
HGF ENSG00000019991 3082 Secreted 0.01587302 33.0 1.116537 0.14204545
INS ENSG00000254647 3630 Secreted 0.01612903 40.0 4.642985 0.10769231
VEGFA ENSG00000112715 7422 Secreted 0.01818182 42.0 4.070636 0.18002323
PDGFB ENSG00000100311 5155 Secreted/Nucleus 0.01851852 58.0 0.7425714 0.12220206
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
EIF2A ENSG00000144895 83939 Cytoplasm 23.0 1.4 1.55E-6 0.0593
GAB1 ENSG00000109458 2549 Cytoplasm 5755.0 15400.0 1.56E-6 6.23E-4
JAK1 ENSG00000162434 3716 Cytoplasm 8612.0 95400.0 1.56E-6 2.71E-4
JAK3 ENSG00000105639 3718 Cytoplasm 4002.0 22800.0 1.56E-6 9.36E-4
LMAN1 ENSG00000074695 3998 Cytoplasm 145.0 8550.0 1.55E-6 0.11
PTPN1 ENSG00000196396 5770 Cytoplasm 1033.0 23200.0 1.56E-6 0.00642
SOS1 ENSG00000115904 6654 Cytoplasm 23511.0 177000.0 1.56E-6 6.54E-5
EIF2AK2 ENSG00000055332 5610 Cytoplasm/Nucleus 120.0 1330.0 1.55E-6 0.0431
KPNA2 ENSG00000182481 3838 Cytoplasm/Nucleus 246.0 3710.0 1.55E-6 0.038
KPNB1 ENSG00000108424 3837 Cytoplasm/Nucleus 732.0 18500.0 1.56E-6 0.00573
PIAS1 ENSG00000033800 8554 Cytoplasm/Nucleus 440.0 6670.0 1.56E-6 0.0131
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 14851.0 1350000.0 1.57E-6 2.68E-4
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 9900.0 278000.0 1.56E-6 2.9E-4
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 7688.0 196000.0 1.56E-6 4.69E-4
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 6515.0 71100.0 1.56E-6 5.43E-4
STAT6 ENSG00000166888 6778 Cytoplasm/Nucleus 2021.0 83000.0 1.56E-6 0.00506
CSF1R ENSG00000182578 1436 Membrane 124.0 10700.0 1.55E-6 0.0404
INSR ENSG00000171105 3643 Membrane 1576.0 21600.0 1.56E-6 0.00205
ITGA1 ENSG00000213949 3672 Membrane 1241.0 12500.0 1.55E-6 0.0102
ITGB1 ENSG00000150093 3688 Membrane 3891.0 368000.0 1.56E-6 0.00113
KDR ENSG00000128052 3791 Membrane 1671.0 16900.0 1.56E-6 0.00306
MET ENSG00000105976 4233 Membrane 1801.0 25400.0 1.56E-6 0.00281
PDGFRB ENSG00000113721 5159 Membrane 3968.0 9730.0 1.56E-6 0.00105
PIK3CA ENSG00000121879 5290 Membrane 27859.0 414000.0 1.56E-6 5.51E-5
PIK3R1 ENSG00000145675 5295 Membrane 31452.0 734000.0 1.56E-6 4.03E-5
SHC1 ENSG00000160691 6464 Membrane 13549.0 312000.0 1.56E-6 2.6E-4
EGFR ENSG00000146648 1956 Unknown 12590.0 758000.0 1.56E-6 2.83E-4
GRB2 ENSG00000177885 2885 Unknown 29079.0 822000.0 1.57E-6 5.64E-5
PIK3CB ENSG00000051382 5291 Unknown 17496.0 62500.0 1.56E-6 1.07E-4
PTPN2 ENSG00000175354 5771 Unknown 185.0 230.0 1.55E-6 0.0199
STAT3 ENSG00000168610 6774 Unknown 10644.0 313000.0 1.56E-6 2.82E-4
ATR ENSG00000175054 545 Nucleus 1918.0 44900.0 1.55E-6 0.00348
CREBBP ENSG00000005339 1387 Nucleus 4940.0 1650000.0 1.57E-6 0.00177
CSF1 ENSG00000184371 1435 Secreted 71.0 158.0 1.55E-6 0.0205
EGF ENSG00000138798 1950 Secreted 4432.0 61100.0 1.56E-6 9.73E-4
HGF ENSG00000019991 3082 Secreted 734.0 9540.0 1.55E-6 0.0038
INS ENSG00000254647 3630 Secreted 1834.0 510000.0 1.56E-6 0.00309
VEGFA ENSG00000112715 7422 Secreted 2210.0 75200.0 1.56E-6 0.00294
PDGFB ENSG00000100311 5155 Secreted/Nucleus 2493.0 26100.0 1.56E-6 0.00256
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
EIF2A ENSG00000144895 83939 Cytoplasm 18.0 9.1 1.30242E-4 0.052287582
GAB1 ENSG00000109458 2549 Cytoplasm 1452.0 4500.0 1.63988E-4 0.00337945
JAK1 ENSG00000162434 3716 Cytoplasm 1074.0 6030.0 1.70999E-4 0.004963546
JAK3 ENSG00000105639 3718 Cytoplasm 606.0 1220.0 1.62022E-4 0.008629954
LMAN1 ENSG00000074695 3998 Cytoplasm 3.0 0.0 1.12032E-4 0.0
PTPN1 ENSG00000196396 5770 Cytoplasm 384.0 4640.0 1.67813E-4 0.011586162
SOS1 ENSG00000115904 6654 Cytoplasm 4430.0 16400.0 1.75009E-4 5.66042E-4
EIF2AK2 ENSG00000055332 5610 Cytoplasm/Nucleus 41.0 173.0 1.53563E-4 0.095121951
KPNA2 ENSG00000182481 3838 Cytoplasm/Nucleus 34.0 13.2 1.49388E-4 0.099821747
KPNB1 ENSG00000108424 3837 Cytoplasm/Nucleus 69.0 1020.0 1.57555E-4 0.04859335
PIAS1 ENSG00000033800 8554 Cytoplasm/Nucleus 85.0 1780.0 1.59872E-4 0.046218487
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 4405.0 181000.0 1.90476E-4 9.50019E-4
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 1671.0 22900.0 1.76929E-4 0.002878265
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 1634.0 35300.0 1.79308E-4 0.003234992
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 1105.0 9710.0 1.73762E-4 0.005193783
STAT6 ENSG00000166888 6778 Cytoplasm/Nucleus 217.0 23300.0 1.57208E-4 0.035756955
CSF1R ENSG00000182578 1436 Membrane 57.0 217.0 1.443E-4 0.071428571
INSR ENSG00000171105 3643 Membrane 260.0 393.0 1.55618E-4 0.017107217
ITGA1 ENSG00000213949 3672 Membrane 202.0 653.0 1.42268E-4 0.070833949
ITGB1 ENSG00000150093 3688 Membrane 912.0 56000.0 1.70126E-4 0.005705125
KDR ENSG00000128052 3791 Membrane 405.0 3500.0 1.64393E-4 0.014778145
MET ENSG00000105976 4233 Membrane 514.0 4460.0 1.69837E-4 0.009534212
PDGFRB ENSG00000113721 5159 Membrane 721.0 6090.0 1.66806E-4 0.008237017
PIK3CA ENSG00000121879 5290 Membrane 7107.0 70400.0 1.83419E-4 2.95273E-4
PIK3R1 ENSG00000145675 5295 Membrane 7548.0 88700.0 1.85288E-4 2.41448E-4
SHC1 ENSG00000160691 6464 Membrane 3723.0 28900.0 1.80538E-4 9.94587E-4
EGFR ENSG00000146648 1956 Unknown 1902.0 59000.0 1.84196E-4 0.002868599
GRB2 ENSG00000177885 2885 Unknown 5986.0 66400.0 1.83857E-4 4.14669E-4
PIK3CB ENSG00000051382 5291 Unknown 1523.0 1830.0 1.61031E-4 0.00262467
PTPN2 ENSG00000175354 5771 Unknown 172.0 2800.0 1.58128E-4 0.021827825
STAT3 ENSG00000168610 6774 Unknown 1951.0 36500.0 1.81521E-4 0.002431889
ATR ENSG00000175054 545 Nucleus 327.0 7010.0 1.51423E-4 0.019999625
CREBBP ENSG00000005339 1387 Nucleus 1251.0 92700.0 1.87512E-4 0.006373142
CSF1 ENSG00000184371 1435 Secreted 41.0 9.06 1.32873E-4 0.025609756
EGF ENSG00000138798 1950 Secreted 836.0 12400.0 1.70561E-4 0.007509383
HGF ENSG00000019991 3082 Secreted 252.0 685.0 1.58932E-4 0.019983558
INS ENSG00000254647 3630 Secreted 266.0 12100.0 1.62681E-4 0.02003121
VEGFA ENSG00000112715 7422 Secreted 517.0 18900.0 1.70765E-4 0.011627907
PDGFB ENSG00000100311 5155 Secreted/Nucleus 475.0 899.0 1.56617E-4 0.017730402
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
CREBBP SRC 3
CREBBP STAT1 6
CREBBP STAT3 7
CREBBP STAT5A 2
CREBBP STAT5B 2
CREBBP STAT6 4
CREBBP VEGFA 3
CSF1 CSF1R 6
EGF EGFR 13
EGF GAB1 2
EGF GRB2 5
EGF MET 1
EGF PDGFRB 1
EGF PIK3CA 2
EGF PIK3R1 3
EGF PTPN1 2
EGFR GAB1 8
EGFR GRB2 12
EGFR JAK1 4
EGFR PIK3CA 4
EGFR PIK3CB 4
EGFR PIK3R1 8
EGFR PTPN1 6
EGFR SHC1 12
EGFR SOS1 9
EGFR SRC 8
EGFR STAT1 7
EGFR STAT3 8
EGFR STAT5A 7
EGFR STAT5B 7
EGFR STAT6 2
EGF SHC1 4
EGF SOS1 4
EGF SRC 3
EGF STAT3 2
EIF2AK2 EIF2A 2
EIF2AK2 PTPN2 1
EIF2AK2 STAT3 3
EIF2A STAT1 1
GAB1 GRB2 9
GAB1 HGF 1
GAB1 MET 6
GAB1 PIK3CA 6
GAB1 PIK3CB 6
GAB1 PIK3R1 8
GAB1 SHC1 8
GAB1 SOS1 6
GAB1 STAT3 3
GRB2 INSR 3
GRB2 JAK1 5
GRB2 MET 4
GRB2 PDGFRB 8
GRB2 PIK3CA 4
GRB2 PIK3CB 4
GRB2 PIK3R1 9
GRB2 PTPN1 4
GRB2 SHC1 13
GRB2 SOS1 12
GRB2 SRC 5
GRB2 STAT3 1
HGF EGFR 1
HGF MET 11
HGF PDGFRB 1
INS EGFR 2
INS INSR 9
INS PIK3CA 2
INS PIK3R1 2
INSR GAB1 1
INSR PIK3CA 3
INSR PIK3R1 9
INSR PTPN1 5
INSR PTPN2 3
INSR SHC1 9
INSR STAT1 1
INSR STAT3 1
INSR STAT5A 3
INSR STAT5B 4
INSR STAT6 1
INS SHC1 2
ITGA1 EGFR 1
ITGA1 ITGB1 10
ITGA1 KDR 1
ITGA1 PTPN2 5
ITGB1 EGFR 2
ITGB1 KDR 1
ITGB1 SRC 3
ITGB1 VEGFA 2
JAK1 GAB1 1
JAK1 JAK3 5
JAK1 PIK3CA 4
JAK1 PIK3CB 3
JAK1 PIK3R1 6
JAK1 PTPN2 3
JAK1 SHC1 4
JAK1 SOS1 2
JAK1 STAT1 9
JAK1 STAT3 11
JAK1 STAT5A 8
JAK1 STAT5B 7
JAK1 STAT6 7
JAK3 PIK3CA 4
JAK3 PIK3CB 3
JAK3 PIK3R1 7
JAK3 SHC1 3
JAK3 SOS1 2
JAK3 STAT1 5
JAK3 STAT3 8
JAK3 STAT5A 9
JAK3 STAT5B 6
JAK3 STAT6 5
KDR GRB2 3
KDR PIK3CA 4
KDR PIK3CB 4
KDR PIK3R1 4
KDR SHC1 5
KDR SRC 9
KDR STAT1 3
KDR STAT3 1
KDR STAT5A 1
KDR STAT5B 1
KDR STAT6 1
KDR VEGFA 10
KPNA2 KPNB1 5
KPNA2 PTPN2 1
KPNB1 HGF 1
KPNB1 MET 1
KPNB1 PTPN2 2
LMAN1 PTPN2 2
MET PIK3CA 2
MET PIK3R1 6
MET SHC1 7
MET SOS1 3
MET SRC 5
MET STAT1 1
MET STAT3 3
MET STAT5A 1
MET STAT5B 1
MET STAT6 1
PDGFB EGFR 1
PDGFB JAK1 1
PDGFB JAK3 1
PDGFB MET 1
PDGFB PDGFRB 10
PDGFB PIK3CA 3
PDGFB PIK3CB 3
PDGFB PIK3R1 3
PDGFB SHC1 4
PDGFB SOS1 4
PDGFB SRC 2
PDGFB STAT1 2
PDGFB STAT3 2
PDGFB STAT5A 2
PDGFB STAT5B 2
PDGFB VEGFA 3
PDGFRB JAK1 1
PDGFRB JAK3 1
PDGFRB PIK3CA 6
PDGFRB PIK3CB 5
PDGFRB PIK3R1 10
PDGFRB SHC1 8
PDGFRB SOS1 5
PDGFRB SRC 8
PDGFRB STAT1 6
PDGFRB STAT3 6
PDGFRB STAT5A 6
PDGFRB STAT5B 4
PDGFRB STAT6 2
PIAS1 STAT1 8
PIAS1 STAT3 4
PIAS1 STAT5A 2
PIAS1 STAT5B 2
PIAS1 STAT6 2
PIK3CA PIK3R1 14
PIK3CA SHC1 3
PIK3CA SOS1 3
PIK3CA STAT1 2
PIK3CA STAT3 3
PIK3CB PIK3CA 2
PIK3CB PIK3R1 10
PIK3CB SHC1 3
PIK3CB SOS1 3
PIK3CB STAT3 2
PIK3R1 SHC1 8
PIK3R1 SOS1 8
PIK3R1 SRC 8
PIK3R1 STAT3 4
PTPN1 CSF1R 1
PTPN1 JAK1 1
PTPN1 MET 1
PTPN1 SRC 5
PTPN1 STAT5A 5
PTPN1 STAT5B 5
PTPN2 CSF1R 1
PTPN2 JAK3 1
PTPN2 KDR 1
PTPN2 MET 1
PTPN2 PDGFRB 1
PTPN2 SHC1 2
PTPN2 SRC 4
PTPN2 STAT1 4
PTPN2 STAT3 3
PTPN2 STAT5A 2
PTPN2 STAT5B 2
PTPN2 STAT6 2
SHC1 SOS1 10
SHC1 SRC 6
SHC1 STAT5A 4
SHC1 STAT5B 3
SOS1 SRC 3
SRC GAB1 4
SRC PIK3CA 2
SRC PIK3CB 2
SRC STAT1 6
SRC STAT3 10
SRC STAT5A 6
SRC STAT5B 4
SRC STAT6 2
STAT1 STAT3 8
STAT1 STAT5A 5
STAT1 STAT5B 3
STAT1 VEGFA 1
STAT3 STAT5A 4
STAT3 STAT5B 6
STAT3 STAT6 2
STAT3 VEGFA 2
STAT5A STAT5B 4
VEGFA PIK3R1 2
VEGFA SRC 4
ATR EGFR 1
ATR KDR 1
ATR PIK3CA 1
CREBBP INSR 1
CREBBP KPNA2 3
CREBBP PIAS1 1
CREBBP PTPN1 1
CSF1 INS 1
CSF1R GRB2 2
CSF1R PIK3R1 4
CSF1R SHC1 2
CSF1R SOS1 2
CSF1R SRC 1
EGF KDR 1
EGF PIK3CB 1
EGFR EIF2AK2 1
EGFR KPNB1 2
EGFR MET 3
EGFR PDGFRB 2
EGFR PTPN2 2
EGF VEGFA 1
EIF2AK2 JAK1 2
EIF2AK2 PDGFRB 2
EIF2AK2 STAT1 2
GAB1 STAT1 1
GAB1 STAT5A 1
GAB1 STAT5B 1
GAB1 STAT6 1
GRB2 HGF 2
GRB2 INS 1
GRB2 JAK3 2
GRB2 KPNA2 2
GRB2 PDGFB 3
HGF KDR 1
HGF PIK3CA 1
HGF PIK3R1 1
HGF SHC1 2
HGF SOS1 2
INS PDGFRB 1
INS PIK3CB 1
INSR JAK1 3
INSR PIK3CB 2
INSR SOS1 2
INSR SRC 1
INS SOS1 1
INS SRC 1
INS STAT3 1
INS VEGFA 1
ITGA1 EGF 1
ITGA1 SHC1 1
ITGA1 SRC 1
ITGA1 VEGFA 1
ITGB1 EGF 1
ITGB1 PTPN1 2
ITGB1 PTPN2 2
ITGB1 SHC1 1
JAK1 EGF 1
JAK1 PIAS1 1
JAK1 SRC 1
JAK3 GAB1 1
KDR GAB1 2
KDR JAK1 1
KDR MET 1
KDR PDGFRB 2
KDR SOS1 1
KPNA2 SRC 1
KPNA2 STAT1 1
KPNB1 SRC 1
MET PIK3CB 1
PDGFB GAB1 2
PDGFB KDR 1
PDGFB STAT6 1
PDGFRB GAB1 2
PDGFRB PTPN1 3
PIAS1 PTPN1 1
PIAS1 SRC 2
PIK3CA STAT5A 1
PIK3CA STAT5B 1
PIK3CA STAT6 1
PIK3CA VEGFA 2
PIK3CB STAT1 1
PIK3CB STAT5A 1
PIK3CB STAT5B 1
PIK3CB STAT6 1
PIK3CB VEGFA 2
PTPN1 CSF1 1
PTPN1 HGF 1
PTPN1 INS 1
PTPN1 PDGFB 1
PTPN1 PIK3CA 1
PTPN1 PIK3R1 1
PTPN1 STAT3 2
PTPN2 CSF1 1
PTPN2 EGF 1
PTPN2 GAB1 1
PTPN2 GRB2 1
PTPN2 HGF 1
PTPN2 INS 1
PTPN2 PDGFB 1
PTPN2 VEGFA 1
SHC1 PTPN1 1
SHC1 STAT3 1
SHC1 STAT6 1
SOS1 PTPN1 1
SOS1 PTPN2 1
SOS1 STAT1 1
SOS1 STAT3 1
SOS1 STAT5A 1
SOS1 STAT5B 1
SOS1 STAT6 1
SRC HGF 1
STAT1 EGF 1
STAT1 SHC1 1
STAT1 STAT6 1
STAT3 KPNB1 1
STAT5A PIK3R1 1
STAT5B PIK3R1 1
STAT5B STAT6 1
STAT6 EGF 1
STAT6 STAT5A 1
VEGFA EGFR 1
VEGFA GAB1 2
VEGFA GRB2 2
VEGFA MET 1
VEGFA PDGFRB 1
VEGFA SHC1 1
VEGFA SOS1 1
Pathway1 Pathway2 Intersect Similarity Scores Pathway Name Source Number of Genes Number of Interactions Detail
pathway0002040 pathway0000868 7 0.6363636 GAB1 signalosome Reactome 11 54
pathway0002040 pathway0000900 5 0.625 Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH 8 29
pathway0002040 pathway0000901 5 0.625 Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH 8 29
pathway0002040 pathway0001995 5 0.625 SHC1 events in EGFR signaling Reactome 8 29
pathway0002040 pathway0000688 7 0.5833333 EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH 12 59
pathway0002040 pathway0000972 4 0.5714286 GRB2 events in EGFR signaling Reactome 7 22
pathway0002040 pathway0001105 4 0.5714286 IL-2 signaling pathway(JAK1 JAK3 STAT5) ( IL-2 signaling(JAK1 JAK3 STAT5) ) INOH 7 22
pathway0002040 pathway0000655 5 0.5555556 EGFR-dependent Endothelin signaling events PID 9 30
pathway0002040 pathway0001164 5 0.5555556 Insulin receptor signalling cascade Reactome 9 30
pathway0002040 pathway0002879 6 0.5454545 Hs_IL-9_Signaling_Pathway_WP22_79264 WikiPathways 11 49
pathway0002040 pathway0001189 6 0.5454545 Interleukin-7 signaling Reactome 11 45
pathway0002040 pathway0001113 7 0.5384615 IL-7 signaling pathway(JAK1 JAK3 STAT5) ( IL-7 signaling(JAK1 JAK3 STAT5) ) INOH 13 65
pathway0002040 pathway0000480 8 0.5333333 Constitutive Signaling by EGFRvIII Reactome 15 107
pathway0002040 pathway0001228 8 0.5333333 JAK/STAT signaling pathway PANTHER 15 87
pathway0002040 pathway0002656 21 0.525 Pathways in cancer KEGG 321 8293
pathway0002040 pathway0002850 3 0.5 Hs_Robo4_and_VEGF_Signaling_Pathways_Crosstalk_WP3943_90823 WikiPathways 6 9
pathway0002040 pathway0000658 20 0.5 EGFR1 NetPath 475 10010
pathway0002040 pathway0002003 5 0.5 Signal attenuation Reactome 10 45
pathway0002040 pathway0002017 5 0.5 Signaling by FGFR3 fusions in cancer Reactome 10 45