Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0002391 Validated targets of C-MYC transcriptional repression PID Homo sapiens 63 385
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
ALDH9A1 ENSG00000143149 223 Cytoplasm 0.008130081 3.0 0.02325581 0.66666667
CDKN2B ENSG00000147883 1030 Cytoplasm 0.008928571 24.0 0.7914326 0.20652174
CSDE1 ENSG00000009307 7812 Cytoplasm 0.008196721 6.0 0.05 0.33333333
FTH1 ENSG00000167996 2495 Cytoplasm 0.008064516 3.0 0.0 0.33333333
HMGCS2 ENSG00000134240 3158 Cytoplasm 0.008333333 4.0 0.0 1.0
NDRG2 ENSG00000165795 57447 Cytoplasm 0.008403361 5.0 0.7790616 0.7
S100A7 ENSG00000143556 6278 Cytoplasm 0.008196721 4.0 0.02325581 0.83333333
SLC11A1 ENSG00000018280 6556 Cytoplasm 0.006993007 3.0 0.0 1.0
BCL2 ENSG00000171791 596 Cytoplasm/Nucleus 0.00877193 12.0 1.376136 0.5
CCND1 ENSG00000110092 595 Cytoplasm/Nucleus 0.009259259 45.0 10.80413 0.07171717
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 0.00952381 43.0 7.049277 0.12735327
CDKN1B ENSG00000111276 1027 Cytoplasm/Nucleus 0.008695652 20.0 1.200739 0.22105263
CFLAR ENSG00000003402 8837 Cytoplasm/Nucleus 0.008130081 3.0 0.0 1.0
DNMT3A ENSG00000119772 1788 Cytoplasm/Nucleus 0.008547009 12.0 0.1344828 0.28787879
EP300 ENSG00000100393 2033 Cytoplasm/Nucleus 0.010204082 56.0 28.49521 0.11558442
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 0.009708738 35.0 13.7146 0.20840336
IRF8 ENSG00000140968 3394 Cytoplasm/Nucleus 0.007194245 7.0 2.375753 0.19047619
LGALS1 ENSG00000100097 3956 Cytoplasm/Nucleus 0.008333333 6.0 0.0 0.4
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 0.015625 109.0 664.6873 0.05317703
NDRG1 ENSG00000104419 10397 Cytoplasm/Nucleus 0.008130081 3.0 0.0 1.0
NFYC ENSG00000066136 4802 Cytoplasm/Nucleus 0.00877193 15.0 1.656163 0.36190476
PPP2R4 ENSG00000119383 5524 Cytoplasm/Nucleus 0.008196721 6.0 0.0 0.4
RBL1 ENSG00000080839 5933 Cytoplasm/Nucleus 0.00952381 36.0 5.919683 0.18412698
SMAD3 ENSG00000166949 4088 Cytoplasm/Nucleus 0.009708738 61.0 20.20347 0.06448087
SMAD4 ENSG00000141646 4089 Cytoplasm/Nucleus 0.009803922 68.0 18.35366 0.05882353
TJP2 ENSG00000119139 9414 Cytoplasm/Nucleus 0.008264463 3.0 0.0 1.0
ZBTB17 ENSG00000116809 7709 Cytoplasm/Nucleus 0.010869565 46.0 136.025 0.13623188
ERBB2 ENSG00000141736 2064 Membrane 0.008849558 12.0 6.960489 0.37878788
ITGA6 ENSG00000091409 3655 Membrane 0.008547009 10.0 0.5222222 0.4
ITGB1 ENSG00000150093 3688 Membrane 0.008849558 15.0 4.635316 0.3047619
PDGFRB ENSG00000113721 5159 Membrane 0.00862069 8.0 5.180625 0.57142857
SFXN3 ENSG00000107819 81855 Membrane 0.008064516 2.0 0.0 1.0
TMEFF2 ENSG00000144339 23671 Membrane 0.008064516 2.0 0.0 1.0
BRCA1 ENSG00000012048 672 Unknown 0.00952381 30.0 19.96438 0.2183908
HDAC3 ENSG00000171720 8841 Unknown 0.009174312 24.0 2.729628 0.26449275
ITGB4 ENSG00000132470 3691 Unknown 0.008695652 11.0 0.98701 0.47272727
MAX ENSG00000125952 4149 Unknown 0.015384615 80.0 478.644 0.09272152
SMAD2 ENSG00000175387 4087 Unknown 0.009433962 57.0 8.96362 0.06203008
TMEM126A ENSG00000171202 84233 Unknown 0.008064516 2.0 0.0 1.0
TSC2 ENSG00000103197 7249 Unknown 0.008333333 8.0 0.07605794 0.39285714
CEBPA ENSG00000245848 1050 Nucleus 0.00952381 27.0 16.31671 0.22507123
CEBPD ENSG00000221869 1052 Nucleus 0.009174312 15.0 1.25102 0.75238095
CREB1 ENSG00000118260 1385 Nucleus 0.009174312 19.0 2.729344 0.43859649
DDIT3 ENSG00000175197 1649 Nucleus 0.009009009 15.0 3.014502 0.45714286
DNTT ENSG00000107447 1791 Nucleus 0.008130081 3.0 0.0 1.0
GADD45A ENSG00000116717 1647 Nucleus 0.008547009 12.0 0.535727 0.45454545
GFI1 ENSG00000162676 2672 Nucleus 0.00877193 12.0 1.718074 0.43939394
GTF2H2 ENSG00000145736 2966 Nucleus 0.008264463 7.0 0.06976744 0.42857143
HDAC1 ENSG00000116478 3065 Nucleus 0.010204082 51.0 29.48794 0.1254902
ID2 ENSG00000115738 3398 Nucleus 0.008547009 11.0 0.9667253 0.45454545
MXD4 ENSG00000123933 10608 Nucleus 0.008333333 5.0 0.0 0.6
NFYA ENSG00000001167 4800 Nucleus 0.009174312 20.0 5.847792 0.35263158
NFYB ENSG00000120837 4801 Nucleus 0.008695652 14.0 1.149628 0.3956044
SP1 ENSG00000185591 6667 Nucleus 0.010416667 48.0 35.78129 0.15780142
SPI1 ENSG00000066336 6688 Nucleus 0.009615385 26.0 46.1391 0.24615385
TBP ENSG00000112592 6908 Nucleus 0.009433962 23.0 22.12789 0.24505929
ZFP36L1 ENSG00000185650 677 Nucleus 0.008196721 4.0 0.05 0.83333333
CCL5 ENSG00000271503 6352 Secreted 0.008333333 4.0 0.01724138 0.83333333
COL1A2 ENSG00000164692 1278 Secreted 0.00877193 14.0 2.031433 0.36263736
DKK1 ENSG00000107984 22943 Secreted 0.008064516 3.0 0.0 0.33333333
SFRP1 ENSG00000104332 6422 Secreted 0.008130081 5.0 0.0 0.3
WNT5A ENSG00000114251 7474 Secreted 0.008403361 7.0 1.473333 0.38095238
CLU ENSG00000120885 1191 Secreted/Nucleus 0.00862069 10.0 1.966499 0.37777778
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
ALDH9A1 ENSG00000143149 223 Cytoplasm 329.0 41700.0 1.55E-6 0.00772852
CDKN2B ENSG00000147883 1030 Cytoplasm 315.0 143.0 1.55E-6 0.007360227
CSDE1 ENSG00000009307 7812 Cytoplasm 6.0 0.0109 1.54E-6 0.333333333
FTH1 ENSG00000167996 2495 Cytoplasm 24.0 21600.0 1.54E-6 0.126811594
HMGCS2 ENSG00000134240 3158 Cytoplasm 1037.0 57500.0 1.55E-6 9.90383E-4
NDRG2 ENSG00000165795 57447 Cytoplasm 5.0 0.282 1.54E-6 0.7
S100A7 ENSG00000143556 6278 Cytoplasm 4.0 0.00104 1.54E-6 0.833333333
SLC11A1 ENSG00000018280 6556 Cytoplasm 3.0 0.0 1.53E-6 1.0
BCL2 ENSG00000171791 596 Cytoplasm/Nucleus 1236.0 33900.0 1.56E-6 0.002475008
CCND1 ENSG00000110092 595 Cytoplasm/Nucleus 2739.0 100000.0 1.56E-6 0.001635868
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 3911.0 109000.0 1.56E-6 8.10489E-4
CDKN1B ENSG00000111276 1027 Cytoplasm/Nucleus 1796.0 58900.0 1.56E-6 0.002642207
CFLAR ENSG00000003402 8837 Cytoplasm/Nucleus 749.0 6840.0 1.55E-6 0.001642118
DNMT3A ENSG00000119772 1788 Cytoplasm/Nucleus 275.0 4350.0 1.55E-6 0.058314532
EP300 ENSG00000100393 2033 Cytoplasm/Nucleus 6386.0 1380000.0 1.56E-6 0.00143089
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 1569.0 45500.0 1.56E-6 0.002198202
IRF8 ENSG00000140968 3394 Cytoplasm/Nucleus 34.0 12800.0 1.54E-6 0.069518717
LGALS1 ENSG00000100097 3956 Cytoplasm/Nucleus 10.0 28.0 1.55E-6 0.177777778
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 4967.0 1640000.0 1.57E-6 0.001945908
NDRG1 ENSG00000104419 10397 Cytoplasm/Nucleus 23.0 106.0 1.55E-6 0.233201581
NFYC ENSG00000066136 4802 Cytoplasm/Nucleus 104.0 7200.0 1.55E-6 0.03995519
PPP2R4 ENSG00000119383 5524 Cytoplasm/Nucleus 66.0 95.0 1.55E-6 0.075524476
RBL1 ENSG00000080839 5933 Cytoplasm/Nucleus 623.0 8730.0 1.56E-6 0.007798589
SMAD3 ENSG00000166949 4088 Cytoplasm/Nucleus 3869.0 321000.0 1.56E-6 9.7372E-4
SMAD4 ENSG00000141646 4089 Cytoplasm/Nucleus 2908.0 151000.0 1.56E-6 0.00134405
TJP2 ENSG00000119139 9414 Cytoplasm/Nucleus 109.0 14000.0 1.55E-6 0.04841998
ZBTB17 ENSG00000116809 7709 Cytoplasm/Nucleus 137.0 17600.0 1.55E-6 0.054851868
ERBB2 ENSG00000141736 2064 Membrane 4475.0 103000.0 1.56E-6 0.001307917
ITGA6 ENSG00000091409 3655 Membrane 2275.0 38500.0 1.56E-6 0.00291146
ITGB1 ENSG00000150093 3688 Membrane 3891.0 368000.0 1.56E-6 0.001127644
PDGFRB ENSG00000113721 5159 Membrane 3968.0 9730.0 1.56E-6 0.001049358
SFXN3 ENSG00000107819 81855 Membrane 2.0 0.0 1.54E-6 1.0
TMEFF2 ENSG00000144339 23671 Membrane 2.0 0.0 1.54E-6 1.0
BRCA1 ENSG00000012048 672 Unknown 3825.0 180000.0 1.56E-6 0.001935352
HDAC3 ENSG00000171720 8841 Unknown 1077.0 29900.0 1.56E-6 0.014205438
ITGB4 ENSG00000132470 3691 Unknown 1484.0 35100.0 1.56E-6 0.007456474
MAX ENSG00000125952 4149 Unknown 704.0 74800.0 1.56E-6 0.016609013
SMAD2 ENSG00000175387 4087 Unknown 3335.0 192000.0 1.56E-6 0.001001359
TMEM126A ENSG00000171202 84233 Unknown 2.0 0.0 1.54E-6 1.0
TSC2 ENSG00000103197 7249 Unknown 891.0 1720.0 1.55E-6 0.002186661
CEBPA ENSG00000245848 1050 Nucleus 541.0 41800.0 1.56E-6 0.021448621
CEBPD ENSG00000221869 1052 Nucleus 85.0 1610.0 1.55E-6 0.122689076
CREB1 ENSG00000118260 1385 Nucleus 1632.0 139000.0 1.56E-6 0.00288302
DDIT3 ENSG00000175197 1649 Nucleus 166.0 9880.0 1.55E-6 0.024096386
DNTT ENSG00000107447 1791 Nucleus 10.0 24.0 1.54E-6 0.511111111
GADD45A ENSG00000116717 1647 Nucleus 339.0 1750.0 1.55E-6 0.010176118
GFI1 ENSG00000162676 2672 Nucleus 12.0 0.328 1.54E-6 0.439393939
GTF2H2 ENSG00000145736 2966 Nucleus 1833.0 2310.0 1.55E-6 0.003041045
HDAC1 ENSG00000116478 3065 Nucleus 3183.0 336000.0 1.56E-6 0.003442629
ID2 ENSG00000115738 3398 Nucleus 100.0 3650.0 1.55E-6 0.079191919
MXD4 ENSG00000123933 10608 Nucleus 5.0 0.0 1.54E-6 0.6
NFYA ENSG00000001167 4800 Nucleus 139.0 16500.0 1.55E-6 0.051402356
NFYB ENSG00000120837 4801 Nucleus 111.0 10500.0 1.55E-6 0.041932842
SP1 ENSG00000185591 6667 Nucleus 1577.0 413000.0 1.56E-6 0.007568344
SPI1 ENSG00000066336 6688 Nucleus 385.0 19000.0 1.56E-6 0.016869589
TBP ENSG00000112592 6908 Nucleus 1719.0 85400.0 1.56E-6 0.007911306
ZFP36L1 ENSG00000185650 677 Nucleus 25.0 3330.0 1.55E-6 0.29
CCL5 ENSG00000271503 6352 Secreted 554.0 19600.0 1.56E-6 0.00904812
COL1A2 ENSG00000164692 1278 Secreted 860.0 61300.0 1.55E-6 0.018342042
DKK1 ENSG00000107984 22943 Secreted 391.0 6730.0 1.55E-6 0.00203292
SFRP1 ENSG00000104332 6422 Secreted 145.0 211.0 1.55E-6 0.022605364
WNT5A ENSG00000114251 7474 Secreted 2802.0 40300.0 1.56E-6 6.54401E-4
CLU ENSG00000120885 1191 Secreted/Nucleus 40.0 5200.0 1.55E-6 0.070512821
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
ALDH9A1 ENSG00000143149 223 Cytoplasm 3.0 0.00685 1.30531E-4 0.666666667
CDKN2B ENSG00000147883 1030 Cytoplasm 64.0 11.2 1.48082E-4 0.099206349
CSDE1 ENSG00000009307 7812 Cytoplasm 6.0 0.00749 1.29769E-4 0.333333333
FTH1 ENSG00000167996 2495 Cytoplasm 3.0 0.0 1.28601E-4 0.333333333
HMGCS2 ENSG00000134240 3158 Cytoplasm 4.0 0.0 1.31096E-4 1.0
NDRG2 ENSG00000165795 57447 Cytoplasm 5.0 0.308 1.29149E-4 0.7
S100A7 ENSG00000143556 6278 Cytoplasm 4.0 0.00685 1.30787E-4 0.833333333
SLC11A1 ENSG00000018280 6556 Cytoplasm 3.0 0.0 1.15101E-4 1.0
BCL2 ENSG00000171791 596 Cytoplasm/Nucleus 336.0 9530.0 1.71409E-4 0.015458422
CCND1 ENSG00000110092 595 Cytoplasm/Nucleus 756.0 16600.0 1.76585E-4 0.005553804
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 806.0 23300.0 1.73702E-4 0.007043447
CDKN1B ENSG00000111276 1027 Cytoplasm/Nucleus 449.0 8600.0 1.7325E-4 0.014237989
CFLAR ENSG00000003402 8837 Cytoplasm/Nucleus 125.0 126.0 1.46135E-4 0.026709677
DNMT3A ENSG00000119772 1788 Cytoplasm/Nucleus 12.0 0.0516 1.32943E-4 0.287878788
EP300 ENSG00000100393 2033 Cytoplasm/Nucleus 1723.0 164000.0 1.88644E-4 0.004008081
FOXO3 ENSG00000118689 2309 Cytoplasm/Nucleus 423.0 5360.0 1.68663E-4 0.014722194
IRF8 ENSG00000140968 3394 Cytoplasm/Nucleus 10.0 206.0 1.31148E-4 0.311111111
LGALS1 ENSG00000100097 3956 Cytoplasm/Nucleus 10.0 87.0 1.38504E-4 0.177777778
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 1512.0 212000.0 1.92234E-4 0.005286628
NDRG1 ENSG00000104419 10397 Cytoplasm/Nucleus 14.0 44.3 1.36911E-4 0.274725275
NFYC ENSG00000066136 4802 Cytoplasm/Nucleus 25.0 5.07 1.42755E-4 0.196666667
PPP2R4 ENSG00000119383 5524 Cytoplasm/Nucleus 22.0 21.5 1.46306E-4 0.181818182
RBL1 ENSG00000080839 5933 Cytoplasm/Nucleus 172.0 535.0 1.54799E-4 0.056643547
SMAD3 ENSG00000166949 4088 Cytoplasm/Nucleus 553.0 19000.0 1.69319E-4 0.010391278
SMAD4 ENSG00000141646 4089 Cytoplasm/Nucleus 586.0 23600.0 1.72533E-4 0.010466439
TJP2 ENSG00000119139 9414 Cytoplasm/Nucleus 3.0 0.0 1.28684E-4 1.0
ZBTB17 ENSG00000116809 7709 Cytoplasm/Nucleus 77.0 1420.0 1.46499E-4 0.065960355
ERBB2 ENSG00000141736 2064 Membrane 319.0 2820.0 1.64718E-4 0.013781274
ITGA6 ENSG00000091409 3655 Membrane 412.0 6290.0 1.5674E-4 0.018106442
ITGB1 ENSG00000150093 3688 Membrane 912.0 56000.0 1.70126E-4 0.005705125
PDGFRB ENSG00000113721 5159 Membrane 721.0 6090.0 1.66806E-4 0.008237016
SFXN3 ENSG00000107819 81855 Membrane 2.0 0.0 1.28601E-4 1.0
TMEFF2 ENSG00000144339 23671 Membrane 2.0 0.0 1.28601E-4 1.0
BRCA1 ENSG00000012048 672 Unknown 576.0 46700.0 1.71999E-4 0.014456522
HDAC3 ENSG00000171720 8841 Unknown 290.0 2660.0 1.60849E-4 0.039327049
ITGB4 ENSG00000132470 3691 Unknown 186.0 7020.0 1.61316E-4 0.047311828
MAX ENSG00000125952 4149 Unknown 381.0 15400.0 1.6592E-4 0.029050974
SMAD2 ENSG00000175387 4087 Unknown 420.0 11000.0 1.6675E-4 0.013285601
TMEM126A ENSG00000171202 84233 Unknown 2.0 0.0 1.28601E-4 1.0
TSC2 ENSG00000103197 7249 Unknown 138.0 923.0 1.54583E-4 0.035121126
CEBPA ENSG00000245848 1050 Nucleus 175.0 6250.0 1.61108E-4 0.044203612
CEBPD ENSG00000221869 1052 Nucleus 69.0 1150.0 1.58278E-4 0.127024723
CREB1 ENSG00000118260 1385 Nucleus 476.0 19700.0 1.76491E-4 0.012976559
DDIT3 ENSG00000175197 1649 Nucleus 59.0 144.0 1.50625E-4 0.098188194
DNTT ENSG00000107447 1791 Nucleus 10.0 39.7 1.29836E-4 0.466666667
GADD45A ENSG00000116717 1647 Nucleus 105.0 1530.0 1.58529E-4 0.064102564
GFI1 ENSG00000162676 2672 Nucleus 12.0 0.694 1.34698E-4 0.439393939
GTF2H2 ENSG00000145736 2966 Nucleus 7.0 0.0205 1.34862E-4 0.428571429
HDAC1 ENSG00000116478 3065 Nucleus 930.0 43900.0 1.76647E-4 0.010037386
ID2 ENSG00000115738 3398 Nucleus 52.0 748.0 1.52625E-4 0.147058824
MXD4 ENSG00000123933 10608 Nucleus 5.0 0.0 1.29316E-4 0.6
NFYA ENSG00000001167 4800 Nucleus 38.0 34.0 1.51722E-4 0.201991465
NFYB ENSG00000120837 4801 Nucleus 29.0 9.72 1.44488E-4 0.204433498
SP1 ENSG00000185591 6667 Nucleus 631.0 40600.0 1.79372E-4 0.014122205
SPI1 ENSG00000066336 6688 Nucleus 135.0 4990.0 1.58403E-4 0.062576009
TBP ENSG00000112592 6908 Nucleus 96.0 955.0 1.56789E-4 0.099561404
ZFP36L1 ENSG00000185650 677 Nucleus 4.0 0.00749 1.29769E-4 0.833333333
CCL5 ENSG00000271503 6352 Secreted 15.0 32.9 1.40925E-4 0.133333333
COL1A2 ENSG00000164692 1278 Secreted 248.0 8580.0 1.58428E-4 0.045546559
DKK1 ENSG00000107984 22943 Secreted 60.0 4250.0 1.50105E-4 0.049717514
SFRP1 ENSG00000104332 6422 Secreted 5.0 0.0 1.29651E-4 0.3
WNT5A ENSG00000114251 7474 Secreted 131.0 6580.0 1.45688E-4 0.017498532
CLU ENSG00000120885 1191 Secreted/Nucleus 10.0 5.51 1.35355E-4 0.377777778
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
BRCA1 EP300 4
BRCA1 GTF2H2 2
BRCA1 HDAC1 5
BRCA1 SMAD3 5
CCND1 CDKN1A 8
CCND1 CDKN1B 6
CCND1 HDAC1 3
CCND1 RBL1 3
CDKN1A HDAC1 4
CDKN1A RBL1 1
CDKN1B RBL1 1
CDKN2B CCND1 2
CEBPA DDIT3 4
CEBPA EP300 2
CEBPA MYC 5
COL1A2 ITGA6 3
COL1A2 ITGB1 4
COL1A2 ITGB4 3
CREB1 EP300 4
CREB1 SPI1 2
DNMT3A MYC 5
DNMT3A ZBTB17 5
EP300 FOXO3 5
EP300 GADD45A 2
EP300 HDAC1 4
EP300 HDAC3 2
EP300 MAX 2
EP300 MYC 5
EP300 SMAD2 8
EP300 SMAD3 9
EP300 SMAD4 7
EP300 SP1 5
EP300 TBP 4
EP300 ZBTB17 3
FOXO3 CDKN1B 2
FOXO3 GADD45A 2
FOXO3 ID2 2
FOXO3 SMAD2 4
FOXO3 SMAD3 8
FOXO3 SMAD4 8
GFI1 ZBTB17 3
HDAC1 HDAC3 3
HDAC1 MAX 3
HDAC1 RBL1 6
HDAC1 SMAD2 6
HDAC1 SMAD3 5
HDAC1 SMAD4 6
HDAC1 SP1 5
HDAC1 SPI1 3
HDAC1 TBP 3
HDAC3 MYC 4
HDAC3 RBL1 4
HDAC3 SMAD2 2
HDAC3 SMAD3 2
HDAC3 SMAD4 3
IRF8 ZBTB17 3
ITGA6 ITGB1 9
ITGA6 ITGB4 11
MAX CCND1 2
MAX MXD4 4
MAX MYC 9
MAX PPP2R4 2
MAX SMAD2 2
MAX SMAD3 5
MAX SMAD4 3
MAX TSC2 2
MAX ZBTB17 2
MYC CCND1 1
MYC CDKN2B 2
MYC NFYA 2
MYC NFYB 4
MYC NFYC 4
MYC PPP2R4 2
MYC SMAD2 5
MYC SMAD3 5
MYC TSC2 3
MYC ZBTB17 7
NFYA NFYB 7
NFYA NFYC 7
NFYA SP1 4
NFYB NFYC 8
NFYB SP1 3
NFYC SP1 3
RBL1 MYC 3
RBL1 SMAD2 2
RBL1 SMAD3 6
RBL1 SMAD4 6
SFRP1 WNT5A 3
SMAD2 CDKN1A 2
SMAD2 CDKN2B 3
SMAD2 SMAD3 9
SMAD2 SMAD4 12
SMAD2 SP1 6
SMAD3 CDKN1A 3
SMAD3 CDKN2B 3
SMAD3 SMAD4 12
SMAD3 SP1 7
SMAD4 CDKN2B 3
SMAD4 MYC 2
SMAD4 SP1 8
SMAD4 ZBTB17 2
SP1 CDKN1A 3
SP1 CDKN2B 3
SP1 TBP 4
SPI1 TBP 5
ZBTB17 CDKN2B 2
ALDH9A1 BRCA1 1
BCL2 BRCA1 2
BCL2 EP300 2
BCL2 ITGB1 2
BCL2 MYC 3
BCL2 NFYA 2
BCL2 ZBTB17 1
BRCA1 CCND1 4
BRCA1 CDKN1A 1
BRCA1 CDKN1B 1
BRCA1 CREB1 1
BRCA1 FOXO3 1
BRCA1 GADD45A 1
BRCA1 ITGB1 2
BRCA1 MYC 5
BRCA1 NFYA 3
BRCA1 RBL1 2
BRCA1 S100A7 1
BRCA1 SMAD2 3
BRCA1 SMAD4 3
BRCA1 SP1 3
BRCA1 TBP 1
CCL5 HDAC1 2
CCND1 EP300 4
CCND1 ERBB2 2
CCND1 HDAC3 4
CCND1 SP1 3
CCND1 TSC2 2
CDKN1A CDKN1B 4
CDKN1A CEBPA 2
CDKN1A EP300 3
CDKN1A GADD45A 2
CDKN1A SMAD4 4
CDKN1B MYC 2
CDKN1B SP1 1
CDKN1B TSC2 2
CDKN2B CDKN1A 1
CDKN2B CDKN1B 1
CEBPA CEBPD 4
CEBPA CLU 1
CEBPA CSDE1 1
CEBPA ERBB2 1
CEBPA FOXO3 1
CEBPA HDAC1 1
CEBPA NFYA 1
CEBPA PDGFRB 1
CEBPA RBL1 1
CEBPA SMAD3 1
CEBPA SMAD4 1
CEBPA SPI1 2
CEBPA WNT5A 1
CEBPA ZFP36L1 1
CEBPD DDIT3 2
CEBPD EP300 2
CEBPD FOXO3 1
CEBPD HDAC1 1
CEBPD HDAC3 1
CEBPD SMAD3 1
CEBPD SMAD4 1
CEBPD SPI1 2
CFLAR SMAD3 2
CLU DNTT 1
CLU ERBB2 1
CLU HDAC1 1
CLU MYC 1
CLU SP1 1
CLU ZBTB17 1
CREB1 BCL2 1
CREB1 CCND1 2
CREB1 CDKN1B 1
CREB1 CEBPD 1
CREB1 FOXO3 1
CREB1 HDAC1 1
CREB1 MAX 1
CREB1 MYC 1
CREB1 NFYA 2
CREB1 RBL1 1
CREB1 SP1 1
DDIT3 BCL2 1
DDIT3 EP300 2
DDIT3 HDAC1 1
DDIT3 ID2 1
DKK1 MYC 3
DNMT3A CDKN1A 1
DNMT3A GFI1 1
DNMT3A HDAC1 2
DNMT3A SPI1 2
EP300 CDKN2B 1
EP300 GTF2H2 1
EP300 NFYA 2
EP300 NFYB 2
EP300 RBL1 1
EP300 SPI1 1
ERBB2 ITGA6 1
ERBB2 ITGB4 2
ERBB2 MYC 1
ERBB2 RBL1 1
ERBB2 SMAD4 2
ERBB2 SPI1 1
FOXO3 CDKN1A 1
FOXO3 CDKN2B 1
FOXO3 HDAC1 1
FOXO3 MYC 2
FOXO3 PDGFRB 1
FOXO3 PPP2R4 1
FOXO3 RBL1 2
FOXO3 SP1 1
FOXO3 ZBTB17 1
FTH1 MAX 2
GADD45A MAX 1
GADD45A SMAD2 2
GADD45A SMAD4 2
GFI1 CCND1 1
GFI1 CDKN1A 1
GFI1 GADD45A 1
GFI1 HDAC1 2
GFI1 ID2 1
GFI1 MYC 1
GFI1 SPI1 2
GTF2H2 TBP 2
HDAC1 MYC 3
HDAC1 NFYA 2
HDAC1 NFYB 1
HDAC1 NFYC 1
HDAC3 DDIT3 1
HDAC3 ID2 1
HDAC3 MAX 1
HDAC3 SP1 1
HDAC3 SPI1 2
HDAC3 TBP 1
ID2 MYC 1
ID2 RBL1 3
ID2 SP1 1
IRF8 ERBB2 1
IRF8 PDGFRB 1
IRF8 SLC11A1 1
IRF8 SPI1 2
ITGB1 ITGB4 1
ITGB1 LGALS1 1
ITGB1 MYC 2
ITGB1 SMAD4 2
ITGB1 TBP 2
ITGB4 SMAD2 2
ITGB4 SMAD3 2
LGALS1 MAX 1
LGALS1 MYC 2
MAX ALDH9A1 1
MAX BCL2 1
MAX CCL5 1
MAX CDKN1A 1
MAX CDKN1B 1
MAX CDKN2B 1
MAX CEBPA 2
MAX CEBPD 1
MAX CFLAR 1
MAX CLU 1
MAX COL1A2 1
MAX CSDE1 2
MAX DDIT3 1
MAX DKK1 1
MAX DNMT3A 1
MAX DNTT 1
MAX ERBB2 1
MAX FOXO3 1
MAX GFI1 1
MAX GTF2H2 1
MAX HMGCS2 1
MAX ID2 1
MAX ITGA6 1
MAX ITGB1 1
MAX ITGB4 1
MAX NDRG1 1
MAX NDRG2 1
MAX NFYA 1
MAX NFYB 1
MAX NFYC 1
MAX PDGFRB 1
MAX RBL1 1
MAX S100A7 1
MAX SFRP1 1
MAX SFXN3 1
MAX SP1 1
MAX TBP 2
MAX TJP2 1
MAX TMEFF2 1
MAX TMEM126A 1
MAX WNT5A 1
MAX ZFP36L1 2
MYC ALDH9A1 1
MYC CCL5 1
MYC CDKN1A 1
MYC CEBPD 1
MYC CFLAR 1
MYC COL1A2 1
MYC CSDE1 2
MYC DDIT3 1
MYC DNTT 1
MYC FTH1 1
MYC GADD45A 1
MYC GTF2H2 1
MYC HMGCS2 1
MYC ITGA6 1
MYC ITGB4 1
MYC MXD4 2
MYC NDRG1 1
MYC NDRG2 1
MYC PDGFRB 1
MYC S100A7 1
MYC SFRP1 1
MYC SFXN3 1
MYC SP1 4
MYC SPI1 1
MYC TBP 5
MYC TJP2 1
MYC TMEFF2 1
MYC TMEM126A 1
MYC WNT5A 1
MYC ZFP36L1 1
NDRG1 NDRG2 1
NFYA DDIT3 1
NFYA PDGFRB 1
NFYA ZBTB17 1
NFYB DDIT3 1
NFYB PDGFRB 1
NFYB TBP 2
NFYC DDIT3 1
NFYC PDGFRB 1
NFYC SMAD2 4
NFYC SMAD3 4
NFYC TBP 1
PPP2R4 SP1 1
RBL1 SP1 4
RBL1 ZBTB17 1
SMAD2 TSC2 2
SMAD2 ZBTB17 1
SMAD3 COL1A2 1
SMAD3 TSC2 2
SMAD3 ZBTB17 1
SMAD4 COL1A2 2
SMAD4 CREB1 1
SMAD4 ID2 1
SP1 CEBPD 1
SP1 COL1A2 1
SP1 HMGCS2 1
SP1 SPI1 1
SP1 ZBTB17 1
SPI1 BCL2 1
SPI1 MAX 1
SPI1 MXD4 1
SPI1 NFYA 1
SPI1 SLC11A1 1
SPI1 WNT5A 1
SPI1 ZBTB17 1
TBP CEBPD 1
TBP COL1A2 1
TBP CSDE1 1
TBP NDRG2 1
TBP S100A7 1
TBP ZFP36L1 1
TJP2 ZBTB17 1
ZBTB17 CCL5 1
ZBTB17 CCND1 1
ZBTB17 CDKN1A 1
ZBTB17 CEBPD 1
ZBTB17 COL1A2 1
ZBTB17 DDIT3 1
ZBTB17 HMGCS2 1
ZBTB17 ITGA6 1
ZBTB17 ITGB1 1
ZBTB17 ITGB4 1
ZBTB17 LGALS1 1
ZBTB17 MXD4 1
ZBTB17 NDRG2 1
ZBTB17 SLC11A1 1
Pathway1 Pathway2 Intersect Similarity Scores Pathway Name Source Number of Genes Number of Interactions Detail