Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0002492 Purine metabolism KEGG Homo sapiens 159 4380
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
ADCY4 ENSG00000129467 196883 Cytoplasm 0.004201681 105.0 62.00391 0.18626374
ADCY6 ENSG00000174233 112 Cytoplasm 0.004115226 104.0 59.90955 0.18782674
ADK ENSG00000156110 132 Cytoplasm 0.004098361 99.0 24.68068 0.21789322
ADSL ENSG00000239900 158 Cytoplasm 0.003184713 36.0 3.964582 0.27936508
ADSS ENSG00000035687 159 Cytoplasm 0.003496503 45.0 6.015236 0.16161616
ADSSL1 ENSG00000185100 122622 Cytoplasm 0.003344482 42.0 4.416865 0.1475029
AK2 ENSG00000004455 204 Cytoplasm 0.004255319 161.0 75.33111 0.10753106
AK5 ENSG00000154027 26289 Cytoplasm 0.004464286 176.0 98.17381 0.11733766
AMPD1 ENSG00000116748 270 Cytoplasm 0.004016064 105.0 57.34069 0.15531136
AMPD3 ENSG00000133805 272 Cytoplasm 0.003984064 96.0 39.53705 0.1752193
DGUOK ENSG00000114956 1716 Cytoplasm 0.003571429 58.0 2.234896 0.23956443
ENTPD4 ENSG00000197217 9583 Cytoplasm 0.003636364 77.0 7.002376 0.13602187
GART ENSG00000159131 2618 Cytoplasm 0.003558719 58.0 4.384081 0.20871143
GDA ENSG00000119125 9615 Cytoplasm 0.002915452 18.0 2.583738 0.21568627
GMPR ENSG00000137198 2766 Cytoplasm 0.003968254 78.0 30.77972 0.25674326
GMPR2 ENSG00000100938 51292 Cytoplasm 0.003968254 73.0 26.76962 0.293379
GUCY1A2 ENSG00000152402 2977 Cytoplasm 0.003984064 97.0 53.14657 0.18535223
GUCY1B3 ENSG00000061918 2983 Cytoplasm 0.004 99.0 53.17142 0.19109462
GUK1 ENSG00000143774 2987 Cytoplasm 0.004366812 153.0 60.43836 0.14026488
HPRT1 ENSG00000165704 3251 Cytoplasm 0.004651163 161.0 567.3154 0.13602484
IMPDH1 ENSG00000106348 3614 Cytoplasm 0.003533569 44.0 1.741175 0.29809725
IMPDH2 ENSG00000178035 3615 Cytoplasm 0.003521127 42.0 1.667649 0.30081301
ITPA ENSG00000125877 3704 Cytoplasm 0.004739336 136.0 138.8149 0.24041394
NME3 ENSG00000103024 4832 Cytoplasm 0.005025126 337.0 286.6473 0.05062173
NME4 ENSG00000103202 4833 Cytoplasm 0.005 333.0 284.6744 0.04998372
NME5 ENSG00000112981 8382 Cytoplasm 0.005050505 300.0 249.9153 0.06434783
NME6 ENSG00000172113 10201 Cytoplasm 0.005025126 336.0 295.1916 0.05092395
NT5C1A ENSG00000116981 84618 Cytoplasm 0.004291845 116.0 69.90954 0.17451274
NT5C2 ENSG00000076685 22978 Cytoplasm 0.004366812 170.0 187.0155 0.08778281
NT5C3 ENSG00000122643 51251 Cytoplasm 0.003984064 80.0 31.74517 0.2193038
NT5M ENSG00000205309 56953 Cytoplasm 0.004291845 157.0 136.3266 0.09782786
NUDT2 ENSG00000164978 318 Cytoplasm 0.004608295 141.0 100.3627 0.2112462
PDE10A ENSG00000112541 10846 Cytoplasm 0.003787879 73.0 18.56862 0.13622527
PDE11A ENSG00000128655 50940 Cytoplasm 0.003773585 69.0 17.24136 0.14194373
PDE1A ENSG00000115252 5136 Cytoplasm 0.003759398 70.0 17.64087 0.12670807
PDE1B ENSG00000123360 5153 Cytoplasm 0.003773585 72.0 18.14125 0.13028169
PDE1C ENSG00000154678 5137 Cytoplasm 0.003759398 71.0 16.82514 0.13038229
PDE3B ENSG00000152270 5140 Cytoplasm 0.003759398 70.0 17.64087 0.12670807
PDE4A ENSG00000065989 5141 Cytoplasm 0.003759398 71.0 16.82514 0.13038229
PDE6D ENSG00000156973 5147 Cytoplasm 0.003802281 68.0 14.69722 0.20544337
PDE6G ENSG00000185527 5148 Cytoplasm 0.003802281 66.0 15.58857 0.21165501
PDE7A ENSG00000205268 5150 Cytoplasm 0.003745318 69.0 16.34171 0.12702472
PDE7B ENSG00000171408 27115 Cytoplasm 0.003759398 71.0 16.82514 0.13038229
PDE8B ENSG00000113231 8622 Cytoplasm 0.003759398 71.0 16.82514 0.13038229
PFAS ENSG00000178921 5198 Cytoplasm 0.003571429 59.0 4.803706 0.21274109
PKLR ENSG00000143627 5313 Cytoplasm 0.005 231.0 144.6539 0.10638058
PNP ENSG00000198805 4860 Cytoplasm 0.003773585 79.0 104.8395 0.18857514
PNPT1 ENSG00000138035 87178 Cytoplasm 0.004132231 198.0 68.1795 0.07219402
PRPS2 ENSG00000101911 5634 Cytoplasm 0.003584229 39.0 61.72431 0.36842105
RRM1 ENSG00000167325 6240 Cytoplasm 0.003460208 62.0 0.645803 0.15758858
XDH ENSG00000158125 7498 Cytoplasm 0.002824859 6.0 0.0 0.2
ADCY10 ENSG00000143199 55811 Cytoplasm/Nucleus 0.004115226 104.0 59.90955 0.18782674
DCK ENSG00000156136 1633 Cytoplasm/Nucleus 0.004065041 103.0 30.0574 0.18789263
FHIT ENSG00000189283 2272 Cytoplasm/Nucleus 0.003460208 24.0 0.4643606 0.80072464
NME1 ENSG00000239672 4830 Cytoplasm/Nucleus 0.005025126 342.0 295.0051 0.04915025
NME2 ENSG00000011052 4831 Cytoplasm/Nucleus 0.005050505 344.0 316.4966 0.04881687
NT5C ENSG00000125458 30833 Cytoplasm/Nucleus 0.004424779 145.0 108.2042 0.15028736
PAPSS2 ENSG00000198682 9060 Cytoplasm/Nucleus 0.003802281 78.0 108.5711 0.21811522
PDE2A ENSG00000186642 5138 Cytoplasm/Nucleus 0.003759398 70.0 17.64087 0.12670807
PDE4D ENSG00000113448 5144 Cytoplasm/Nucleus 0.003759398 71.0 16.82514 0.13038229
PDE5A ENSG00000138735 8654 Cytoplasm/Nucleus 0.003745318 62.0 15.46308 0.14912745
POLR2D ENSG00000144231 5433 Cytoplasm/Nucleus 0.004016064 151.0 5.511406 0.1592053
PRUNE ENSG00000143363 58497 Cytoplasm/Nucleus 0.003584229 57.0 2.138299 0.23433584
RRM2 ENSG00000171848 6241 Cytoplasm/Nucleus 0.003460208 96.0 1.07564 0.06535088
RRM2B ENSG00000048392 50484 Cytoplasm/Nucleus 0.003484321 92.0 1.516242 0.07883421
ADA ENSG00000196839 100 Membrane 0.002967359 35.0 1.716845 0.1210084
ADCY1 ENSG00000164742 107 Membrane 0.004132231 106.0 60.9009 0.19317161
ADCY2 ENSG00000078295 108 Membrane 0.004166667 104.0 59.27796 0.20351008
ADCY3 ENSG00000138031 109 Membrane 0.004504505 96.0 69.68874 0.31666667
ADCY5 ENSG00000173175 111 Membrane 0.004132231 105.0 59.92381 0.19688645
ADCY7 ENSG00000121281 113 Membrane 0.004115226 104.0 59.90955 0.18782674
ADCY8 ENSG00000155897 114 Membrane 0.004132231 102.0 60.92648 0.17938264
ADCY9 ENSG00000162104 115 Membrane 0.004115226 105.0 60.88664 0.18424908
AK1 ENSG00000106992 203 Membrane 0.004255319 166.0 76.40702 0.10259219
ENPP1 ENSG00000197594 5167 Membrane 0.003610108 58.0 22.87662 0.18209316
ENPP3 ENSG00000154269 5169 Membrane 0.002832861 16.0 4.066948 0.1
ENTPD1 ENSG00000138185 953 Membrane 0.004716981 245.0 217.1961 0.07189696
ENTPD2 ENSG00000054179 954 Membrane 0.0041841 99.0 15.93807 0.29169243
ENTPD3 ENSG00000168032 956 Membrane 0.004854369 205.0 192.6113 0.11080823
ENTPD8 ENSG00000188833 377841 Membrane 0.004672897 231.0 181.1579 0.07957839
GUCY2C ENSG00000070019 2984 Membrane 0.003968254 95.0 53.14657 0.17894737
GUCY2D ENSG00000132518 3000 Membrane 0.004366812 87.0 63.21056 0.33012563
GUCY2F ENSG00000101890 2986 Membrane 0.003968254 95.0 53.14657 0.17894737
NPR1 ENSG00000169418 4881 Membrane 0.003968254 95.0 53.14657 0.17894737
NPR2 ENSG00000159899 4882 Membrane 0.003875969 93.0 52.35849 0.16736793
NT5E ENSG00000135318 4907 Membrane 0.004310345 159.0 142.8513 0.09672797
PDE3A ENSG00000172572 5139 Membrane 0.003773585 72.0 18.14125 0.13028169
PDE6A ENSG00000132915 5145 Membrane 0.003816794 69.0 15.74731 0.21184996
PDE6B ENSG00000133256 5158 Membrane 0.003816794 69.0 15.74731 0.21184996
PDE8A ENSG00000073417 5151 Membrane 0.003745318 69.0 16.34171 0.12702472
AK4 ENSG00000162433 205 Unknown 0.004255319 158.0 77.11868 0.10344272
AK7 ENSG00000140057 122481 Unknown 0.003952569 130.0 39.07201 0.10971974
AMPD2 ENSG00000116337 271 Unknown 0.003984064 95.0 38.67403 0.17894737
APRT ENSG00000198931 353 Unknown 0.004587156 158.0 233.699 0.14536806
ATIC ENSG00000138363 471 Unknown 0.003831418 100.0 57.16826 0.14141414
GMPS ENSG00000163655 8833 Unknown 0.004310345 110.0 147.6592 0.20650542
GUCY1A3 ENSG00000164116 2982 Unknown 0.003984064 97.0 53.14657 0.18535223
NME1-NME2 ENSG00000011052 654364 Unknown 0.004901961 298.0 213.3769 0.05809776
NME7 ENSG00000143156 29922 Unknown 0.005 332.0 287.3884 0.05028574
NT5C1B ENSG00000185013 93034 Unknown 0.004291845 158.0 138.5619 0.09658953
NUDT5 ENSG00000165609 11164 Unknown 0.002816901 7.0 0.06779661 0.23809524
NUDT9 ENSG00000170502 53343 Unknown 0.002816901 6.0 0.06779661 0.33333333
PDE4B ENSG00000184588 5142 Unknown 0.003759398 72.0 17.28801 0.12676056
PDE4C ENSG00000105650 5143 Unknown 0.003773585 70.0 17.77929 0.12960663
PDE6C ENSG00000095464 5146 Unknown 0.003802281 66.0 14.24948 0.22703963
PDE6H ENSG00000139053 5149 Unknown 0.003773585 64.0 14.23043 0.1984127
PDE9A ENSG00000160191 5152 Unknown 0.003745318 62.0 15.46308 0.14912745
POLR2J3 ENSG00000168255 548644 Unknown 0.003921569 122.0 2.80347 0.22029535
POLR3A ENSG00000148606 11128 Unknown 0.003921569 153.0 2.80347 0.13983488
POLR3G ENSG00000113356 10622 Unknown 0.003921569 145.0 2.80347 0.15574713
POLR3GL ENSG00000121851 84265 Unknown 0.003921569 139.0 2.80347 0.16953394
PRPS1 ENSG00000147224 5631 Unknown 0.002890173 11.0 1.337454 0.27272727
PRPS1L1 ENSG00000229937 221823 Unknown 0.003623188 42.0 70.34533 0.35772358
PAICS ENSG00000128050 10606 Nucleus 0.003558719 61.0 10.40816 0.18797814
PAPSS1 ENSG00000138801 9061 Nucleus 0.002610966 14.0 0.3759285 0.05494505
POLA1 ENSG00000101868 5422 Nucleus 0.003636364 91.0 0.7730831 0.12112332
POLA2 ENSG00000014138 23649 Nucleus 0.003636364 87.0 0.7673359 0.13258487
POLD1 ENSG00000062822 5424 Nucleus 0.003787879 101.0 4.587971 0.1570297
POLD2 ENSG00000106628 5425 Nucleus 0.003787879 98.0 4.239595 0.16684199
POLD3 ENSG00000077514 10714 Nucleus 0.003787879 99.0 4.306016 0.16347145
POLD4 ENSG00000175482 57804 Nucleus 0.003787879 100.0 4.239595 0.16020202
POLE ENSG00000177084 5426 Nucleus 0.003787879 101.0 4.530446 0.1570297
POLE2 ENSG00000100479 5427 Nucleus 0.003787879 99.0 4.388958 0.16347145
POLE3 ENSG00000148229 54107 Nucleus 0.003623188 86.0 0.5468991 0.12913817
POLE4 ENSG00000115350 56655 Nucleus 0.003623188 87.0 0.5468991 0.12616947
POLR1A ENSG00000068654 25885 Nucleus 0.003921569 146.0 2.80347 0.1536136
POLR1B ENSG00000125630 84172 Nucleus 0.003921569 144.0 2.80347 0.15792541
POLR1C ENSG00000171453 9533 Nucleus 0.003921569 161.0 2.80347 0.12624224
POLR1D ENSG00000186184 51082 Nucleus 0.003921569 155.0 2.80347 0.13623796
POLR1E ENSG00000137054 64425 Nucleus 0.003921569 141.0 2.80347 0.16474164
POLR2A ENSG00000181222 5430 Nucleus 0.004347826 187.0 62.82412 0.12103962
POLR2B ENSG00000047315 5431 Nucleus 0.004016064 155.0 5.649645 0.15106829
POLR2C ENSG00000102978 5432 Nucleus 0.004016064 155.0 5.647941 0.15106829
POLR2E ENSG00000099817 5434 Nucleus 0.004016064 179.0 6.408483 0.11317557
POLR2F ENSG00000100142 5435 Nucleus 0.004016064 181.0 6.478729 0.1106814
POLR2G ENSG00000168002 5436 Nucleus 0.004048583 152.0 7.19599 0.15815615
POLR2H ENSG00000163882 5437 Nucleus 0.004016064 178.0 6.373667 0.11445439
POLR2I ENSG00000105258 5438 Nucleus 0.004016064 152.0 5.546022 0.15711049
POLR2J ENSG00000005075 5439 Nucleus 0.004016064 152.0 5.544314 0.15711049
POLR2J2 ENSG00000267645 246721 Nucleus 0.003921569 122.0 2.80347 0.22029535
POLR2K ENSG00000147669 5440 Nucleus 0.004016064 168.0 6.062591 0.12852866
POLR2L ENSG00000177700 5441 Nucleus 0.004016064 173.0 6.234851 0.12118564
POLR3B ENSG00000013503 55703 Nucleus 0.003921569 151.0 2.80347 0.14357616
POLR3C ENSG00000186141 10623 Nucleus 0.003921569 151.0 2.80347 0.14357616
POLR3D ENSG00000168495 661 Nucleus 0.003921569 150.0 2.80347 0.14550336
POLR3F ENSG00000132664 10621 Nucleus 0.003921569 148.0 2.80347 0.14947601
POLR3H ENSG00000100413 171568 Nucleus 0.003921569 147.0 2.80347 0.15152362
POLR3K ENSG00000161980 51728 Nucleus 0.004366812 178.0 54.9006 0.13222878
PPAT ENSG00000128059 5471 Nucleus 0.003676471 54.0 49.88974 0.19217331
PRIM1 ENSG00000198056 5557 Nucleus 0.003623188 87.0 0.5468991 0.12616947
PRIM2 ENSG00000146143 5558 Nucleus 0.003649635 89.0 2.243322 0.12972421
ZNRD1 ENSG00000066379 30834 Nucleus 0.003921569 136.0 2.80347 0.17712418
CANT1 ENSG00000171302 124583 Secreted 0.003861004 109.0 19.13053 0.13421679
ENTPD5 ENSG00000187097 957 Secreted 0.003759398 74.0 8.639365 0.22769345
ENTPD6 ENSG00000197586 955 Secreted 0.003636364 77.0 7.002376 0.13602187
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
ADCY4 ENSG00000129467 196883 Cytoplasm 2340.0 33300.0 1.55E-6 4.97692E-4
ADCY6 ENSG00000174233 112 Cytoplasm 2751.0 44300.0 1.55E-6 4.44136E-4
ADK ENSG00000156110 132 Cytoplasm 325.0 4370.0 1.54E-6 0.02674264
ADSL ENSG00000239900 158 Cytoplasm 460.0 986.0 1.53E-6 0.001676613
ADSS ENSG00000035687 159 Cytoplasm 595.0 3280.0 1.54E-6 0.001109131
ADSSL1 ENSG00000185100 122622 Cytoplasm 201.0 1410.0 1.54E-6 0.008308458
AK2 ENSG00000004455 204 Cytoplasm 431.0 2160.0 1.54E-6 0.018065073
AK5 ENSG00000154027 26289 Cytoplasm 479.0 2460.0 1.54E-6 0.018308715
AMPD1 ENSG00000116748 270 Cytoplasm 799.0 1550.0 1.54E-6 0.00277289
AMPD3 ENSG00000133805 272 Cytoplasm 177.0 339.0 1.54E-6 0.053479712
DGUOK ENSG00000114956 1716 Cytoplasm 403.0 20.6 1.54E-6 0.004888708
ENTPD4 ENSG00000197217 9583 Cytoplasm 200.0 160.0 1.54E-6 0.024824121
GART ENSG00000159131 2618 Cytoplasm 583.0 12400.0 1.54E-6 0.00291772
GDA ENSG00000119125 9615 Cytoplasm 368.0 414.0 1.53E-6 8.14477E-4
GMPR ENSG00000137198 2766 Cytoplasm 667.0 829.0 1.54E-6 0.00365583
GMPR2 ENSG00000100938 51292 Cytoplasm 147.0 150.0 1.54E-6 0.075668624
GUCY1A2 ENSG00000152402 2977 Cytoplasm 400.0 6060.0 1.55E-6 0.012293233
GUCY1B3 ENSG00000061918 2983 Cytoplasm 418.0 7670.0 1.55E-6 0.011978934
GUK1 ENSG00000143774 2987 Cytoplasm 1185.0 12000.0 1.54E-6 0.002816741
HPRT1 ENSG00000165704 3251 Cytoplasm 1099.0 25400.0 1.54E-6 0.003034718
IMPDH1 ENSG00000106348 3614 Cytoplasm 446.0 26.1 1.52E-6 0.00301305
IMPDH2 ENSG00000178035 3615 Cytoplasm 134.0 6.93 1.52E-6 0.030972955
ITPA ENSG00000125877 3704 Cytoplasm 801.0 9340.0 1.54E-6 0.007562422
NME3 ENSG00000103024 4832 Cytoplasm 1482.0 15800.0 1.54E-6 0.003178361
NME4 ENSG00000103202 4833 Cytoplasm 1532.0 20900.0 1.54E-6 0.002894062
NME5 ENSG00000112981 8382 Cytoplasm 1258.0 10100.0 1.54E-6 0.004403955
NME6 ENSG00000172113 10201 Cytoplasm 2629.0 47900.0 1.54E-6 0.00100738
NT5C1A ENSG00000116981 84618 Cytoplasm 220.0 1960.0 1.54E-6 0.058405978
NT5C2 ENSG00000076685 22978 Cytoplasm 1498.0 42600.0 1.54E-6 0.001408246
NT5C3 ENSG00000122643 51251 Cytoplasm 139.0 527.0 1.54E-6 0.087165051
NT5M ENSG00000205309 56953 Cytoplasm 419.0 7060.0 1.54E-6 0.017197474
NUDT2 ENSG00000164978 318 Cytoplasm 645.0 5660.0 1.54E-6 0.010573451
PDE10A ENSG00000112541 10846 Cytoplasm 497.0 2360.0 1.54E-6 0.003537353
PDE11A ENSG00000128655 50940 Cytoplasm 92.0 289.0 1.54E-6 0.095078834
PDE1A ENSG00000115252 5136 Cytoplasm 192.0 6480.0 1.54E-6 0.023887435
PDE1B ENSG00000123360 5153 Cytoplasm 189.0 5800.0 1.54E-6 0.026286165
PDE1C ENSG00000154678 5137 Cytoplasm 164.0 4990.0 1.54E-6 0.028954063
PDE3B ENSG00000152270 5140 Cytoplasm 229.0 11400.0 1.55E-6 0.023021528
PDE4A ENSG00000065989 5141 Cytoplasm 157.0 1480.0 1.55E-6 0.03829822
PDE6D ENSG00000156973 5147 Cytoplasm 127.0 102.0 1.54E-6 0.060867392
PDE6G ENSG00000185527 5148 Cytoplasm 201.0 9620.0 1.54E-6 0.028855721
PDE7A ENSG00000205268 5150 Cytoplasm 148.0 550.0 1.54E-6 0.03438132
PDE7B ENSG00000171408 27115 Cytoplasm 151.0 566.0 1.54E-6 0.035496689
PDE8B ENSG00000113231 8622 Cytoplasm 151.0 566.0 1.54E-6 0.035496689
PFAS ENSG00000178921 5198 Cytoplasm 528.0 178.0 1.54E-6 0.002803174
PKLR ENSG00000143627 5313 Cytoplasm 861.0 198000.0 1.55E-6 0.008867461
PNP ENSG00000198805 4860 Cytoplasm 799.0 16300.0 1.54E-6 0.002427847
PNPT1 ENSG00000138035 87178 Cytoplasm 378.0 1820.0 1.54E-6 0.022455195
PRPS2 ENSG00000101911 5634 Cytoplasm 72.0 7370.0 1.54E-6 0.1228482
RRM1 ENSG00000167325 6240 Cytoplasm 817.0 18900.0 1.55E-6 0.001895985
XDH ENSG00000158125 7498 Cytoplasm 148.0 2300.0 1.53E-6 0.001103144
ADCY10 ENSG00000143199 55811 Cytoplasm/Nucleus 269.0 2330.0 1.55E-6 0.032125617
DCK ENSG00000156136 1633 Cytoplasm/Nucleus 283.0 930.0 1.54E-6 0.027090695
FHIT ENSG00000189283 2272 Cytoplasm/Nucleus 31.0 428.0 1.54E-6 0.501075269
NME1 ENSG00000239672 4830 Cytoplasm/Nucleus 1758.0 286000.0 1.56E-6 0.002501938
NME2 ENSG00000011052 4831 Cytoplasm/Nucleus 1698.0 124000.0 1.55E-6 0.002484118
NT5C ENSG00000125458 30833 Cytoplasm/Nucleus 472.0 31100.0 1.54E-6 0.019000324
PAPSS2 ENSG00000198682 9060 Cytoplasm/Nucleus 174.0 87800.0 1.54E-6 0.047505149
PDE2A ENSG00000186642 5138 Cytoplasm/Nucleus 150.0 582.0 1.54E-6 0.034183445
PDE4D ENSG00000113448 5144 Cytoplasm/Nucleus 510.0 34600.0 1.55E-6 0.004391541
PDE5A ENSG00000138735 8654 Cytoplasm/Nucleus 120.0 389.0 1.54E-6 0.041736695
POLR2D ENSG00000144231 5433 Cytoplasm/Nucleus 3789.0 53400.0 1.56E-6 0.003198137
PRUNE ENSG00000143363 58497 Cytoplasm/Nucleus 57.0 21.7 1.54E-6 0.23433584
RRM2 ENSG00000171848 6241 Cytoplasm/Nucleus 1369.0 47700.0 1.55E-6 6.5357E-4
RRM2B ENSG00000048392 50484 Cytoplasm/Nucleus 930.0 28300.0 1.55E-6 0.001259303
ADA ENSG00000196839 100 Membrane 375.0 39100.0 1.55E-6 0.001454546
ADCY1 ENSG00000164742 107 Membrane 2940.0 52000.0 1.55E-6 3.61547E-4
ADCY2 ENSG00000078295 108 Membrane 3341.0 68900.0 1.55E-6 2.96265E-4
ADCY3 ENSG00000138031 109 Membrane 2863.0 108000.0 1.55E-6 4.79137E-4
ADCY5 ENSG00000173175 111 Membrane 2434.0 39700.0 1.55E-6 6.18043E-4
ADCY7 ENSG00000121281 113 Membrane 2610.0 47800.0 1.55E-6 3.88282E-4
ADCY8 ENSG00000155897 114 Membrane 2866.0 48500.0 1.55E-6 3.63898E-4
ADCY9 ENSG00000162104 115 Membrane 2547.0 42900.0 1.55E-6 4.10199E-4
AK1 ENSG00000106992 203 Membrane 1101.0 6360.0 1.54E-6 0.002733053
ENPP1 ENSG00000197594 5167 Membrane 182.0 72300.0 1.54E-6 0.026349341
ENPP3 ENSG00000154269 5169 Membrane 76.0 3640.0 1.53E-6 0.033333333
ENTPD1 ENSG00000138185 953 Membrane 578.0 7860.0 1.54E-6 0.014698386
ENTPD2 ENSG00000054179 954 Membrane 126.0 198.0 1.54E-6 0.183365079
ENTPD3 ENSG00000168032 956 Membrane 486.0 5820.0 1.54E-6 0.022960418
ENTPD8 ENSG00000188833 377841 Membrane 1158.0 9410.0 1.54E-6 0.003464681
GUCY2C ENSG00000070019 2984 Membrane 144.0 656.0 1.54E-6 0.077700078
GUCY2D ENSG00000132518 3000 Membrane 166.0 3740.0 1.54E-6 0.092442497
GUCY2F ENSG00000101890 2986 Membrane 199.0 2560.0 1.54E-6 0.04172377
NPR1 ENSG00000169418 4881 Membrane 151.0 7740.0 1.55E-6 0.072317881
NPR2 ENSG00000159899 4882 Membrane 144.0 4750.0 1.54E-6 0.06954157
NT5E ENSG00000135318 4907 Membrane 458.0 25500.0 1.54E-6 0.014715297
PDE3A ENSG00000172572 5139 Membrane 230.0 13300.0 1.55E-6 0.023922537
PDE6A ENSG00000132915 5145 Membrane 212.0 9570.0 1.54E-6 0.027497094
PDE6B ENSG00000133256 5158 Membrane 212.0 9570.0 1.54E-6 0.027497094
PDE8A ENSG00000073417 5151 Membrane 148.0 550.0 1.54E-6 0.03438132
AK4 ENSG00000162433 205 Unknown 401.0 2000.0 1.54E-6 0.018778055
AK7 ENSG00000140057 122481 Unknown 327.0 1310.0 1.54E-6 0.021200353
AMPD2 ENSG00000116337 271 Unknown 175.0 335.0 1.54E-6 0.054712644
APRT ENSG00000198931 353 Unknown 925.0 4460.0 1.54E-6 0.004293904
ATIC ENSG00000138363 471 Unknown 1051.0 17500.0 1.54E-6 0.001580354
GMPS ENSG00000163655 8833 Unknown 986.0 36800.0 1.54E-6 0.002959195
GUCY1A3 ENSG00000164116 2982 Unknown 245.0 3460.0 1.55E-6 0.032786885
NME1-NME2 ENSG00000011052 654364 Unknown 549.0 3710.0 1.54E-6 0.019099092
NME7 ENSG00000143156 29922 Unknown 1344.0 11200.0 1.54E-6 0.003709712
NT5C1B ENSG00000185013 93034 Unknown 410.0 6650.0 1.54E-6 0.017818594
NUDT5 ENSG00000165609 11164 Unknown 58.0 0.244 1.52E-6 0.003024803
NUDT9 ENSG00000170502 53343 Unknown 6.0 0.0135 1.52E-6 0.333333333
PDE4B ENSG00000184588 5142 Unknown 166.0 2210.0 1.55E-6 0.035341366
PDE4C ENSG00000105650 5143 Unknown 154.0 1440.0 1.55E-6 0.037178508
PDE6C ENSG00000095464 5146 Unknown 133.0 1010.0 1.54E-6 0.060378218
PDE6H ENSG00000139053 5149 Unknown 130.0 1030.0 1.54E-6 0.053190221
PDE9A ENSG00000160191 5152 Unknown 120.0 3200.0 1.55E-6 0.042717087
POLR2J3 ENSG00000168255 548644 Unknown 252.0 57.6 1.54E-6 0.054006197
POLR3A ENSG00000148606 11128 Unknown 812.0 2360.0 1.54E-6 0.00700953
POLR3G ENSG00000113356 10622 Unknown 750.0 1440.0 1.54E-6 0.008145972
POLR3GL ENSG00000121851 84265 Unknown 698.0 1440.0 1.54E-6 0.009405845
PRPS1 ENSG00000147224 5631 Unknown 41.0 190.0 1.53E-6 0.076829268
PRPS1L1 ENSG00000229937 221823 Unknown 378.0 18000.0 1.54E-6 0.004771729
PAICS ENSG00000128050 10606 Nucleus 534.0 628.0 1.54E-6 0.002578859
PAPSS1 ENSG00000138801 9061 Nucleus 75.0 4300.0 1.53E-6 0.012972973
POLA1 ENSG00000101868 5422 Nucleus 523.0 11900.0 1.55E-6 0.010629803
POLA2 ENSG00000014138 23649 Nucleus 407.0 2530.0 1.55E-6 0.014136842
POLD1 ENSG00000062822 5424 Nucleus 1025.0 43000.0 1.55E-6 0.007782012
POLD2 ENSG00000106628 5425 Nucleus 940.0 18800.0 1.55E-6 0.009088437
POLD3 ENSG00000077514 10714 Nucleus 918.0 17500.0 1.55E-6 0.009382209
POLD4 ENSG00000175482 57804 Nucleus 930.0 17100.0 1.55E-6 0.009111428
POLE ENSG00000177084 5426 Nucleus 731.0 17900.0 1.55E-6 0.016400877
POLE2 ENSG00000100479 5427 Nucleus 713.0 17700.0 1.55E-6 0.017240021
POLE3 ENSG00000148229 54107 Nucleus 162.0 65.4 1.54E-6 0.040564374
POLE4 ENSG00000115350 56655 Nucleus 164.0 65.4 1.54E-6 0.039578034
POLR1A ENSG00000068654 25885 Nucleus 916.0 7350.0 1.55E-6 0.015477128
POLR1B ENSG00000125630 84172 Nucleus 903.0 9780.0 1.55E-6 0.016382936
POLR1C ENSG00000171453 9533 Nucleus 1421.0 7690.0 1.55E-6 0.006716159
POLR1D ENSG00000186184 51082 Nucleus 1410.0 19600.0 1.55E-6 0.007198909
POLR1E ENSG00000137054 64425 Nucleus 876.0 6690.0 1.55E-6 0.017268102
POLR2A ENSG00000181222 5430 Nucleus 5457.0 272000.0 1.56E-6 0.001626486
POLR2B ENSG00000047315 5431 Nucleus 3961.0 57300.0 1.56E-6 0.002927533
POLR2C ENSG00000102978 5432 Nucleus 4042.0 64600.0 1.56E-6 0.00287185
POLR2E ENSG00000099817 5434 Nucleus 5565.0 130000.0 1.56E-6 0.001653745
POLR2F ENSG00000100142 5435 Nucleus 5346.0 87500.0 1.56E-6 0.001759339
POLR2G ENSG00000168002 5436 Nucleus 3789.0 47600.0 1.56E-6 0.003188243
POLR2H ENSG00000163882 5437 Nucleus 5512.0 134000.0 1.56E-6 0.001695185
POLR2I ENSG00000105258 5438 Nucleus 3711.0 55000.0 1.56E-6 0.003354491
POLR2J ENSG00000005075 5439 Nucleus 3907.0 49200.0 1.56E-6 0.003018202
POLR2J2 ENSG00000267645 246721 Nucleus 252.0 57.6 1.54E-6 0.054006197
POLR2K ENSG00000147669 5440 Nucleus 5078.0 93200.0 1.56E-6 0.001964547
POLR2L ENSG00000177700 5441 Nucleus 5190.0 119000.0 1.56E-6 0.001904429
POLR3B ENSG00000013503 55703 Nucleus 799.0 1480.0 1.54E-6 0.007176891
POLR3C ENSG00000186141 10623 Nucleus 826.0 1870.0 1.54E-6 0.006715093
POLR3D ENSG00000168495 661 Nucleus 822.0 2950.0 1.55E-6 0.006801391
POLR3F ENSG00000132664 10621 Nucleus 802.0 1730.0 1.54E-6 0.007123266
POLR3H ENSG00000100413 171568 Nucleus 783.0 1470.0 1.54E-6 0.007473388
POLR3K ENSG00000161980 51728 Nucleus 798.0 7750.0 1.54E-6 0.008830105
PPAT ENSG00000128059 5471 Nucleus 687.0 10100.0 1.54E-6 0.001896953
PRIM1 ENSG00000198056 5557 Nucleus 439.0 7500.0 1.55E-6 0.012003204
PRIM2 ENSG00000146143 5558 Nucleus 421.0 2390.0 1.55E-6 0.013188553
ZNRD1 ENSG00000066379 30834 Nucleus 751.0 2010.0 1.55E-6 0.021628052
CANT1 ENSG00000171302 124583 Secreted 402.0 18700.0 1.54E-6 0.012903066
ENTPD5 ENSG00000187097 957 Secreted 572.0 493.0 1.54E-6 0.004849791
ENTPD6 ENSG00000197586 955 Secreted 200.0 160.0 1.54E-6 0.024824121
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
ADCY4 ENSG00000129467 196883 Cytoplasm 1271.0 43700.0 4.19E-6 0.001424881
ADCY6 ENSG00000174233 112 Cytoplasm 1258.0 29600.0 4.19E-6 0.001625239
ADK ENSG00000156110 132 Cytoplasm 99.0 396.0 4.15E-6 0.217893218
ADSL ENSG00000239900 158 Cytoplasm 48.0 850.0 4.11E-6 0.156914894
ADSS ENSG00000035687 159 Cytoplasm 66.0 2390.0 4.12E-6 0.089044289
ADSSL1 ENSG00000185100 122622 Cytoplasm 63.0 1510.0 4.11E-6 0.079877112
AK2 ENSG00000004455 204 Cytoplasm 161.0 1440.0 4.16E-6 0.107531056
AK5 ENSG00000154027 26289 Cytoplasm 176.0 1610.0 4.16E-6 0.117337662
AMPD1 ENSG00000116748 270 Cytoplasm 105.0 1280.0 4.13E-6 0.155311355
AMPD3 ENSG00000133805 272 Cytoplasm 96.0 792.0 4.14E-6 0.175219298
DGUOK ENSG00000114956 1716 Cytoplasm 58.0 23.3 4.12E-6 0.239564428
ENTPD4 ENSG00000197217 9583 Cytoplasm 137.0 131.0 4.12E-6 0.050450837
GART ENSG00000159131 2618 Cytoplasm 93.0 57000.0 4.14E-6 0.105890603
GDA ENSG00000119125 9615 Cytoplasm 18.0 16.2 4.08E-6 0.215686275
GMPR ENSG00000137198 2766 Cytoplasm 78.0 585.0 4.13E-6 0.256743257
GMPR2 ENSG00000100938 51292 Cytoplasm 73.0 512.0 4.13E-6 0.293378995
GUCY1A2 ENSG00000152402 2977 Cytoplasm 167.0 7240.0 4.18E-6 0.065507539
GUCY1B3 ENSG00000061918 2983 Cytoplasm 179.0 13000.0 4.19E-6 0.06195468
GUK1 ENSG00000143774 2987 Cytoplasm 153.0 861.0 4.15E-6 0.140264878
HPRT1 ENSG00000165704 3251 Cytoplasm 178.0 13600.0 4.15E-6 0.11470831
IMPDH1 ENSG00000106348 3614 Cytoplasm 51.0 5.55 4.09E-6 0.221176471
IMPDH2 ENSG00000178035 3615 Cytoplasm 49.0 5.93 4.09E-6 0.220238095
ITPA ENSG00000125877 3704 Cytoplasm 245.0 3670.0 4.16E-6 0.078822349
NME3 ENSG00000103024 4832 Cytoplasm 616.0 19400.0 4.17E-6 0.016772252
NME4 ENSG00000103202 4833 Cytoplasm 609.0 20500.0 4.17E-6 0.01660401
NME5 ENSG00000112981 8382 Cytoplasm 543.0 17800.0 4.17E-6 0.021725687
NME6 ENSG00000172113 10201 Cytoplasm 615.0 21500.0 4.17E-6 0.016916925
NT5C1A ENSG00000116981 84618 Cytoplasm 196.0 5040.0 4.15E-6 0.07299843
NT5C2 ENSG00000076685 22978 Cytoplasm 272.0 11900.0 4.15E-6 0.040563273
NT5C3 ENSG00000122643 51251 Cytoplasm 139.0 2020.0 4.14E-6 0.086018142
NT5M ENSG00000205309 56953 Cytoplasm 255.0 9370.0 4.15E-6 0.044526787
NUDT2 ENSG00000164978 318 Cytoplasm 235.0 1970.0 4.16E-6 0.077868703
PDE10A ENSG00000112541 10846 Cytoplasm 73.0 119.0 4.15E-6 0.136225266
PDE11A ENSG00000128655 50940 Cytoplasm 69.0 97.1 4.14E-6 0.141943734
PDE1A ENSG00000115252 5136 Cytoplasm 100.0 14800.0 4.17E-6 0.071313131
PDE1B ENSG00000123360 5153 Cytoplasm 99.0 14400.0 4.17E-6 0.078334364
PDE1C ENSG00000154678 5137 Cytoplasm 98.0 9480.0 4.17E-6 0.078055965
PDE3B ENSG00000152270 5140 Cytoplasm 145.0 33900.0 4.19E-6 0.04559387
PDE4A ENSG00000065989 5141 Cytoplasm 71.0 77.8 4.14E-6 0.130382294
PDE6D ENSG00000156973 5147 Cytoplasm 68.0 85.7 4.15E-6 0.205443371
PDE6G ENSG00000185527 5148 Cytoplasm 84.0 1780.0 4.15E-6 0.148594378
PDE7A ENSG00000205268 5150 Cytoplasm 69.0 76.1 4.14E-6 0.127024723
PDE7B ENSG00000171408 27115 Cytoplasm 71.0 77.8 4.14E-6 0.130382294
PDE8B ENSG00000113231 8622 Cytoplasm 71.0 77.8 4.14E-6 0.130382294
PFAS ENSG00000178921 5198 Cytoplasm 59.0 108.0 4.13E-6 0.212741087
PKLR ENSG00000143627 5313 Cytoplasm 404.0 577000.0 4.2E-6 0.0386458
PNP ENSG00000198805 4860 Cytoplasm 161.0 13100.0 4.15E-6 0.05636646
PNPT1 ENSG00000138035 87178 Cytoplasm 378.0 3960.0 4.15E-6 0.022342919
PRPS2 ENSG00000101911 5634 Cytoplasm 71.0 20100.0 4.15E-6 0.126358149
RRM1 ENSG00000167325 6240 Cytoplasm 119.0 3500.0 4.14E-6 0.057256801
XDH ENSG00000158125 7498 Cytoplasm 13.0 1370.0 4.1E-6 0.102564103
ADCY10 ENSG00000143199 55811 Cytoplasm/Nucleus 104.0 398.0 4.15E-6 0.187826736
DCK ENSG00000156136 1633 Cytoplasm/Nucleus 166.0 1890.0 4.14E-6 0.077838627
FHIT ENSG00000189283 2272 Cytoplasm/Nucleus 31.0 3420.0 4.16E-6 0.48172043
NME1 ENSG00000239672 4830 Cytoplasm/Nucleus 624.0 19500.0 4.17E-6 0.01634461
NME2 ENSG00000011052 4831 Cytoplasm/Nucleus 626.0 21000.0 4.17E-6 0.016316933
NT5C ENSG00000125458 30833 Cytoplasm/Nucleus 258.0 16200.0 4.15E-6 0.058486412
PAPSS2 ENSG00000198682 9060 Cytoplasm/Nucleus 113.0 233000.0 4.13E-6 0.107932996
PDE2A ENSG00000186642 5138 Cytoplasm/Nucleus 70.0 99.9 4.14E-6 0.126708075
PDE4D ENSG00000113448 5144 Cytoplasm/Nucleus 71.0 77.8 4.14E-6 0.130382294
PDE5A ENSG00000138735 8654 Cytoplasm/Nucleus 62.0 91.5 4.14E-6 0.149127446
POLR2D ENSG00000144231 5433 Cytoplasm/Nucleus 342.0 4210.0 4.17E-6 0.033750064
PRUNE ENSG00000143363 58497 Cytoplasm/Nucleus 57.0 116.0 4.13E-6 0.23433584
RRM2 ENSG00000171848 6241 Cytoplasm/Nucleus 195.0 39900.0 4.17E-6 0.020724293
RRM2B ENSG00000048392 50484 Cytoplasm/Nucleus 194.0 44300.0 4.17E-6 0.023449602
ADA ENSG00000196839 100 Membrane 35.0 1.34 4.08E-6 0.121008403
ADCY1 ENSG00000164742 107 Membrane 1644.0 128000.0 4.2E-6 9.82566E-4
ADCY2 ENSG00000078295 108 Membrane 1145.0 51500.0 4.2E-6 0.002053623
ADCY3 ENSG00000138031 109 Membrane 1719.0 192000.0 4.2E-6 0.001183107
ADCY5 ENSG00000173175 111 Membrane 973.0 27300.0 4.19E-6 0.002952136
ADCY7 ENSG00000121281 113 Membrane 1092.0 45300.0 4.2E-6 0.001902009
ADCY8 ENSG00000155897 114 Membrane 1576.0 62300.0 4.2E-6 9.58021E-4
ADCY9 ENSG00000162104 115 Membrane 1441.0 50500.0 4.2E-6 0.0010901
AK1 ENSG00000106992 203 Membrane 166.0 1410.0 4.15E-6 0.102592187
ENPP1 ENSG00000197594 5167 Membrane 126.0 89800.0 4.14E-6 0.051174603
ENPP3 ENSG00000154269 5169 Membrane 61.0 6120.0 4.09E-6 0.040983607
ENTPD1 ENSG00000138185 953 Membrane 451.0 5850.0 4.15E-6 0.02340478
ENTPD2 ENSG00000054179 954 Membrane 99.0 322.0 4.14E-6 0.291692435
ENTPD3 ENSG00000168032 956 Membrane 370.0 6930.0 4.15E-6 0.038350546
ENTPD8 ENSG00000188833 377841 Membrane 421.0 4660.0 4.14E-6 0.026083022
GUCY2C ENSG00000070019 2984 Membrane 95.0 217.0 4.15E-6 0.178947368
GUCY2D ENSG00000132518 3000 Membrane 101.0 1660.0 4.15E-6 0.24970297
GUCY2F ENSG00000101890 2986 Membrane 110.0 765.0 4.15E-6 0.136780651
NPR1 ENSG00000169418 4881 Membrane 98.0 287.0 4.17E-6 0.168525142
NPR2 ENSG00000159899 4882 Membrane 93.0 216.0 4.15E-6 0.167367929
NT5E ENSG00000135318 4907 Membrane 257.0 9730.0 4.15E-6 0.043987111
PDE3A ENSG00000172572 5139 Membrane 142.0 28300.0 4.19E-6 0.050044951
PDE6A ENSG00000132915 5145 Membrane 88.0 1780.0 4.15E-6 0.146551724
PDE6B ENSG00000133256 5158 Membrane 88.0 1780.0 4.15E-6 0.146551724
PDE8A ENSG00000073417 5151 Membrane 69.0 76.1 4.14E-6 0.127024723
AK4 ENSG00000162433 205 Unknown 158.0 1410.0 4.15E-6 0.103442716
AK7 ENSG00000140057 122481 Unknown 130.0 899.0 4.15E-6 0.109719738
AMPD2 ENSG00000116337 271 Unknown 95.0 785.0 4.14E-6 0.178947368
APRT ENSG00000198931 353 Unknown 158.0 2330.0 4.15E-6 0.145368056
ATIC ENSG00000138363 471 Unknown 141.0 50500.0 4.13E-6 0.082066869
GMPS ENSG00000163655 8833 Unknown 123.0 7600.0 4.15E-6 0.169265627
GUCY1A3 ENSG00000164116 2982 Unknown 167.0 7240.0 4.18E-6 0.065507539
NME1-NME2 ENSG00000011052 654364 Unknown 549.0 16000.0 4.16E-6 0.018992727
NME7 ENSG00000143156 29922 Unknown 605.0 19300.0 4.17E-6 0.016764271
NT5C1B ENSG00000185013 93034 Unknown 253.0 9190.0 4.15E-6 0.044858523
NUDT5 ENSG00000165609 11164 Unknown 7.0 0.0227 4.08E-6 0.238095238
NUDT9 ENSG00000170502 53343 Unknown 6.0 0.0227 4.08E-6 0.333333333
PDE4B ENSG00000184588 5142 Unknown 72.0 80.0 4.14E-6 0.126760563
PDE4C ENSG00000105650 5143 Unknown 70.0 78.6 4.14E-6 0.129606625
PDE6C ENSG00000095464 5146 Unknown 66.0 68.3 4.14E-6 0.227039627
PDE6H ENSG00000139053 5149 Unknown 64.0 68.3 4.14E-6 0.198412698
PDE9A ENSG00000160191 5152 Unknown 62.0 91.5 4.14E-6 0.149127446
POLR2J3 ENSG00000168255 548644 Unknown 252.0 107.0 4.16E-6 0.054006197
POLR3A ENSG00000148606 11128 Unknown 328.0 2850.0 4.17E-6 0.032128739
POLR3G ENSG00000113356 10622 Unknown 308.0 107.0 4.16E-6 0.03612674
POLR3GL ENSG00000121851 84265 Unknown 291.0 107.0 4.16E-6 0.04047873
PRPS1 ENSG00000147224 5631 Unknown 41.0 528.0 4.09E-6 0.076829268
PRPS1L1 ENSG00000229937 221823 Unknown 72.0 13500.0 4.15E-6 0.133020344
PAICS ENSG00000128050 10606 Nucleus 61.0 164.0 4.13E-6 0.187978142
PAPSS1 ENSG00000138801 9061 Nucleus 53.0 10300.0 4.09E-6 0.023222061
POLA1 ENSG00000101868 5422 Nucleus 172.0 489.0 4.15E-6 0.037739698
POLA2 ENSG00000014138 23649 Nucleus 164.0 489.0 4.15E-6 0.041523268
POLD1 ENSG00000062822 5424 Nucleus 192.0 836.0 4.15E-6 0.046465969
POLD2 ENSG00000106628 5425 Nucleus 186.0 683.0 4.15E-6 0.049520488
POLD3 ENSG00000077514 10714 Nucleus 188.0 683.0 4.15E-6 0.048469678
POLD4 ENSG00000175482 57804 Nucleus 190.0 683.0 4.15E-6 0.047451963
POLE ENSG00000177084 5426 Nucleus 192.0 686.0 4.15E-6 0.046465969
POLE2 ENSG00000100479 5427 Nucleus 188.0 685.0 4.15E-6 0.048469678
POLE3 ENSG00000148229 54107 Nucleus 162.0 336.0 4.14E-6 0.040564374
POLE4 ENSG00000115350 56655 Nucleus 164.0 336.0 4.14E-6 0.039578034
POLR1A ENSG00000068654 25885 Nucleus 274.0 107.0 4.16E-6 0.045667228
POLR1B ENSG00000125630 84172 Nucleus 270.0 107.0 4.16E-6 0.047032907
POLR1C ENSG00000171453 9533 Nucleus 344.0 319.0 4.16E-6 0.028968066
POLR1D ENSG00000186184 51082 Nucleus 340.0 23300.0 4.18E-6 0.029932327
POLR1E ENSG00000137054 64425 Nucleus 264.0 107.0 4.16E-6 0.049199217
POLR2A ENSG00000181222 5430 Nucleus 447.0 82000.0 4.19E-6 0.024558341
POLR2B ENSG00000047315 5431 Nucleus 350.0 4180.0 4.18E-6 0.032419157
POLR2C ENSG00000102978 5432 Nucleus 356.0 3240.0 4.18E-6 0.032394366
POLR2E ENSG00000099817 5434 Nucleus 409.0 9600.0 4.18E-6 0.024629656
POLR2F ENSG00000100142 5435 Nucleus 407.0 3220.0 4.17E-6 0.024642645
POLR2G ENSG00000168002 5436 Nucleus 341.0 3310.0 4.17E-6 0.034155598
POLR2H ENSG00000163882 5437 Nucleus 401.0 3200.0 4.17E-6 0.025386534
POLR2I ENSG00000105258 5438 Nucleus 346.0 6370.0 4.18E-6 0.033023373
POLR2J ENSG00000005075 5439 Nucleus 341.0 1880.0 4.17E-6 0.033862343
POLR2J2 ENSG00000267645 246721 Nucleus 252.0 107.0 4.16E-6 0.054006197
POLR2K ENSG00000147669 5440 Nucleus 378.0 7550.0 4.18E-6 0.02790058
POLR2L ENSG00000177700 5441 Nucleus 390.0 2730.0 4.17E-6 0.026801134
POLR3B ENSG00000013503 55703 Nucleus 322.0 107.0 4.16E-6 0.033048896
POLR3C ENSG00000186141 10623 Nucleus 323.0 107.0 4.16E-6 0.032844259
POLR3D ENSG00000168495 661 Nucleus 321.0 107.0 4.16E-6 0.033255452
POLR3F ENSG00000132664 10621 Nucleus 316.0 107.0 4.16E-6 0.034317862
POLR3H ENSG00000100413 171568 Nucleus 313.0 107.0 4.16E-6 0.03497993
POLR3K ENSG00000161980 51728 Nucleus 363.0 4120.0 4.16E-6 0.033894952
PPAT ENSG00000128059 5471 Nucleus 85.0 20000.0 4.15E-6 0.11232493
PRIM1 ENSG00000198056 5557 Nucleus 164.0 336.0 4.14E-6 0.039578034
PRIM2 ENSG00000146143 5558 Nucleus 167.0 527.0 4.15E-6 0.04090614
ZNRD1 ENSG00000066379 30834 Nucleus 254.0 107.0 4.16E-6 0.053157387
CANT1 ENSG00000171302 124583 Secreted 194.0 847.0 4.14E-6 0.05143956
ENTPD5 ENSG00000187097 957 Secreted 134.0 354.0 4.13E-6 0.084502301
ENTPD6 ENSG00000197586 955 Secreted 137.0 131.0 4.12E-6 0.050450837
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
ADCY10 PDE10A 4
ADCY10 PDE11A 3
ADCY10 PDE1A 3
ADCY10 PDE1B 4
ADCY10 PDE1C 4
ADCY10 PDE2A 3
ADCY10 PDE3A 4
ADCY10 PDE3B 3
ADCY10 PDE4A 4
ADCY10 PDE4B 4
ADCY10 PDE4C 3
ADCY10 PDE4D 4
ADCY10 PDE5A 2
ADCY10 PDE6A 2
ADCY10 PDE6B 2
ADCY10 PDE6C 2
ADCY10 PDE6D 2
ADCY10 PDE6G 2
ADCY10 PDE6H 2
ADCY10 PDE7A 3
ADCY10 PDE7B 4
ADCY10 PDE8A 3
ADCY10 PDE8B 4
ADCY10 PDE9A 2
ADCY1 PDE10A 4
ADCY1 PDE11A 3
ADCY1 PDE1A 3
ADCY1 PDE1B 4
ADCY1 PDE1C 4
ADCY1 PDE2A 3
ADCY1 PDE3A 4
ADCY1 PDE3B 3
ADCY1 PDE4A 4
ADCY1 PDE4B 4
ADCY1 PDE4C 3
ADCY1 PDE4D 4
ADCY1 PDE5A 2
ADCY1 PDE6A 2
ADCY1 PDE6B 2
ADCY1 PDE6C 2
ADCY1 PDE6D 2
ADCY1 PDE6G 2
ADCY1 PDE6H 2
ADCY1 PDE7A 3
ADCY1 PDE7B 4
ADCY1 PDE8A 3
ADCY1 PDE8B 4
ADCY1 PDE9A 2
ADCY2 PDE10A 3
ADCY2 PDE11A 2
ADCY2 PDE1A 3
ADCY2 PDE1B 3
ADCY2 PDE1C 3
ADCY2 PDE2A 3
ADCY2 PDE3A 3
ADCY2 PDE3B 3
ADCY2 PDE4A 3
ADCY2 PDE4B 3
ADCY2 PDE4C 3
ADCY2 PDE4D 4
ADCY2 PDE5A 2
ADCY2 PDE6A 2
ADCY2 PDE6B 2
ADCY2 PDE6C 2
ADCY2 PDE6D 2
ADCY2 PDE6G 2
ADCY2 PDE6H 2
ADCY2 PDE7A 3
ADCY2 PDE7B 3
ADCY2 PDE8A 3
ADCY2 PDE8B 3
ADCY2 PDE9A 2
ADCY4 PDE10A 4
ADCY4 PDE11A 3
ADCY4 PDE1A 3
ADCY4 PDE1B 4
ADCY4 PDE1C 4
ADCY4 PDE2A 3
ADCY4 PDE3A 4
ADCY4 PDE3B 3
ADCY4 PDE4A 4
ADCY4 PDE4B 4
ADCY4 PDE4C 3
ADCY4 PDE4D 4
ADCY4 PDE5A 2
ADCY4 PDE6A 2
ADCY4 PDE6B 2
ADCY4 PDE6C 2
ADCY4 PDE6D 2
ADCY4 PDE6G 2
ADCY4 PDE6H 2
ADCY4 PDE7A 3
ADCY4 PDE7B 4
ADCY4 PDE8A 3
ADCY4 PDE8B 4
ADCY4 PDE9A 2
ADCY5 PDE10A 4
ADCY5 PDE11A 3
ADCY5 PDE1A 3
ADCY5 PDE1B 4
ADCY5 PDE1C 4
ADCY5 PDE2A 3
ADCY5 PDE3A 4
ADCY5 PDE3B 3
ADCY5 PDE4A 4
ADCY5 PDE4B 4
ADCY5 PDE4C 3
ADCY5 PDE4D 4
ADCY5 PDE5A 2
ADCY5 PDE6A 2
ADCY5 PDE6B 2
ADCY5 PDE6C 2
ADCY5 PDE6D 2
ADCY5 PDE6G 2
ADCY5 PDE6H 2
ADCY5 PDE7A 3
ADCY5 PDE7B 4
ADCY5 PDE8A 3
ADCY5 PDE8B 4
ADCY5 PDE9A 2
ADCY6 PDE10A 4
ADCY6 PDE11A 3
ADCY6 PDE1A 3
ADCY6 PDE1B 4
ADCY6 PDE1C 4
ADCY6 PDE2A 3
ADCY6 PDE3A 4
ADCY6 PDE3B 3
ADCY6 PDE4A 4
ADCY6 PDE4B 4
ADCY6 PDE4C 3
ADCY6 PDE4D 4
ADCY6 PDE5A 2
ADCY6 PDE6A 2
ADCY6 PDE6B 2
ADCY6 PDE6C 2
ADCY6 PDE6D 2
ADCY6 PDE6G 2
ADCY6 PDE6H 2
ADCY6 PDE7A 3
ADCY6 PDE7B 4
ADCY6 PDE8A 3
ADCY6 PDE8B 4
ADCY6 PDE9A 2
ADCY7 PDE10A 4
ADCY7 PDE11A 3
ADCY7 PDE1A 3
ADCY7 PDE1B 4
ADCY7 PDE1C 4
ADCY7 PDE2A 3
ADCY7 PDE3A 4
ADCY7 PDE3B 3
ADCY7 PDE4A 4
ADCY7 PDE4B 4
ADCY7 PDE4C 3
ADCY7 PDE4D 4
ADCY7 PDE5A 2
ADCY7 PDE6A 2
ADCY7 PDE6B 2
ADCY7 PDE6C 2
ADCY7 PDE6D 2
ADCY7 PDE6G 2
ADCY7 PDE6H 2
ADCY7 PDE7A 3
ADCY7 PDE7B 4
ADCY7 PDE8A 3
ADCY7 PDE8B 4
ADCY7 PDE9A 2
ADCY8 PDE10A 3
ADCY8 PDE11A 2
ADCY8 PDE1A 3
ADCY8 PDE1B 3
ADCY8 PDE1C 3
ADCY8 PDE2A 3
ADCY8 PDE3A 3
ADCY8 PDE3B 3
ADCY8 PDE4A 3
ADCY8 PDE4B 3
ADCY8 PDE4C 3
ADCY8 PDE4D 3
ADCY8 PDE5A 2
ADCY8 PDE6A 2
ADCY8 PDE6B 2
ADCY8 PDE6C 2
ADCY8 PDE6D 2
ADCY8 PDE6G 2
ADCY8 PDE6H 2
ADCY8 PDE7A 3
ADCY8 PDE7B 3
ADCY8 PDE8A 3
ADCY8 PDE8B 3
ADCY8 PDE9A 2
ADCY9 PDE10A 4
ADCY9 PDE11A 3
ADCY9 PDE1A 3
ADCY9 PDE1B 4
ADCY9 PDE1C 4
ADCY9 PDE2A 3
ADCY9 PDE3A 4
ADCY9 PDE3B 3
ADCY9 PDE4A 4
ADCY9 PDE4B 4
ADCY9 PDE4C 3
ADCY9 PDE4D 4
ADCY9 PDE5A 2
ADCY9 PDE6A 2
ADCY9 PDE6B 2
ADCY9 PDE6C 2
ADCY9 PDE6D 2
ADCY9 PDE6G 2
ADCY9 PDE6H 2
ADCY9 PDE7A 3
ADCY9 PDE7B 4
ADCY9 PDE8A 3
ADCY9 PDE8B 4
ADCY9 PDE9A 2
ADK AK1 4
ADK AK2 3
ADK AK4 3
ADK AK5 4
ADK AK7 3
ADK AMPD1 4
ADK AMPD2 4
ADK AMPD3 4
ADK APRT 2
ADSL ATIC 8
ADSL NT5C2 2
ADSS ADSL 7
ADSSL1 ADSL 6
AK1 AMPD1 3
AK1 AMPD2 3
AK1 AMPD3 3
AK1 NME1 5
AK1 NME2 5
AK1 NT5C 3
AK1 NT5C1B 2
AK1 NT5C2 4
AK1 NT5E 2
AK1 NT5M 2
AK1 RRM1 5
AK1 RRM2 5
AK1 RRM2B 3
AK2 AMPD1 2
AK2 AMPD2 2
AK2 AMPD3 2
AK2 NME1 5
AK2 NME2 6
AK2 NT5C 2
AK2 NT5C1B 2
AK2 NT5C2 2
AK2 NT5E 2
AK2 NT5M 2
AK2 PKLR 5
AK2 RRM1 4
AK2 RRM2 4
AK2 RRM2B 3
AK4 AMPD1 2
AK4 AMPD2 2
AK4 AMPD3 2
AK4 NT5C 2
AK4 NT5C1B 2
AK4 NT5C2 2
AK4 NT5E 2
AK4 NT5M 2
AK4 PKLR 4
AK4 RRM1 4
AK4 RRM2 4
AK4 RRM2B 3
AK5 AMPD1 3
AK5 AMPD2 3
AK5 AMPD3 3
AK5 NME1 5
AK5 NME2 5
AK5 NME3 5
AK5 NME4 5
AK5 NME5 4
AK5 NME6 4
AK5 NME7 4
AK5 NT5C 3
AK5 NT5C1B 2
AK5 NT5C2 3
AK5 NT5E 2
AK5 NT5M 2
AK5 PKLR 5
AK5 RRM1 5
AK5 RRM2 5
AK5 RRM2B 3
AK7 AMPD1 2
AK7 AMPD2 2
AK7 AMPD3 2
AK7 NT5C2 2
AK7 RRM1 3
AK7 RRM2 3
AK7 RRM2B 2
AMPD1 ADSS 6
AMPD1 ADSSL1 5
AMPD1 ATIC 4
AMPD1 HPRT1 3
AMPD1 IMPDH1 6
AMPD1 IMPDH2 5
AMPD1 NT5C 2
AMPD1 NT5C1B 2
AMPD1 NT5C2 6
AMPD1 NT5E 2
AMPD1 NT5M 2
AMPD2 ADSS 5
AMPD2 ADSSL1 4
AMPD2 ATIC 3
AMPD2 HPRT1 2
AMPD2 IMPDH1 5
AMPD2 IMPDH2 5
AMPD2 NT5C 2
AMPD2 NT5C1B 2
AMPD2 NT5C2 5
AMPD2 NT5E 2
AMPD2 NT5M 2
AMPD3 ADSS 5
AMPD3 ADSSL1 4
AMPD3 ATIC 3
AMPD3 HPRT1 2
AMPD3 IMPDH1 5
AMPD3 IMPDH2 5
AMPD3 NT5C 2
AMPD3 NT5C1B 2
AMPD3 NT5C2 5
AMPD3 NT5E 3
AMPD3 NT5M 2
APRT AK1 6
APRT AK2 5
APRT AK4 4
APRT AK5 5
APRT AK7 3
APRT AMPD1 6
APRT AMPD2 5
APRT AMPD3 5
APRT GDA 3
APRT HPRT1 4
APRT NT5C1A 2
APRT NT5C1B 3
APRT NT5C2 5
APRT NT5E 3
APRT NT5M 2
ATIC ADSS 7
ATIC ADSSL1 6
ATIC GART 3
ATIC IMPDH1 6
ATIC IMPDH2 6
ATIC NME2 3
ATIC PAICS 2
CANT1 ADSS 2
CANT1 ADSSL1 2
CANT1 APRT 2
CANT1 ATIC 2
CANT1 GMPR 2
CANT1 GMPR2 2
CANT1 HPRT1 2
CANT1 IMPDH1 2
CANT1 IMPDH2 2
CANT1 NT5C 2
CANT1 NT5C1A 1
CANT1 NT5C1B 2
CANT1 NT5C2 3
CANT1 NT5C3 1
CANT1 NT5E 2
CANT1 NT5M 2
DCK AK5 2
DGUOK GUK1 2
ENPP1 NT5C1B 2
ENPP1 NT5C2 2
ENPP1 NT5E 2
ENPP1 NT5M 2
ENPP3 NT5C 2
ENPP3 NT5C1B 2
ENPP3 NT5C2 2
ENPP3 NT5E 2
ENPP3 NT5M 2
ENTPD1 ADSS 2
ENTPD1 ADSSL1 2
ENTPD1 AK1 3
ENTPD1 AK2 3
ENTPD1 AK4 3
ENTPD1 AK5 3
ENTPD1 AK7 2
ENTPD1 AMPD1 3
ENTPD1 AMPD2 3
ENTPD1 AMPD3 3
ENTPD1 APRT 2
ENTPD1 ATIC 2
ENTPD1 CANT1 2
ENTPD1 ENTPD4 2
ENTPD1 ENTPD5 2
ENTPD1 ENTPD6 2
ENTPD1 GMPR 2
ENTPD1 GMPR2 2
ENTPD1 HPRT1 2
ENTPD1 IMPDH1 2
ENTPD1 IMPDH2 2
ENTPD1 NT5C 3
ENTPD1 NT5C1A 2
ENTPD1 NT5C1B 2
ENTPD1 NT5C2 4
ENTPD1 NT5C3 1
ENTPD1 NT5E 3
ENTPD1 NT5M 3
ENTPD1 RRM1 3
ENTPD1 RRM2 3
ENTPD1 RRM2B 2
ENTPD2 AK1 2
ENTPD2 AK2 2