Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0002722 Hs_Senescence_and_Autophagy_in_Cancer_WP615_81193 WikiPathways Homo sapiens 62 254
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
AKT1S1 ENSG00000204673 84335 Cytoplasm 0.007352941 5.0 8.858172 0.3
ATG7 ENSG00000197548 10533 Cytoplasm 0.006097561 11.0 0.0 0.10909091
BRAF ENSG00000157764 673 Cytoplasm 0.007692308 40.0 5.70953 0.02435897
GABARAPL2 ENSG00000034713 11345 Cytoplasm 0.006410256 11.0 3.483875 0.29090909
GSN ENSG00000148180 2934 Cytoplasm 0.007407407 8.0 0.1128225 0.28571429
IGF1 ENSG00000017427 3479 Cytoplasm 0.007092199 32.0 17.37486 0.02822581
IKBKE ENSG00000263528 9641 Cytoplasm 0.00625 5.0 3.525296 0.3
MLST8 ENSG00000167965 64223 Cytoplasm 0.006493506 11.0 18.76324 0.14545455
SERPINB2 ENSG00000197632 5055 Cytoplasm 0.006756757 6.0 18.8322 0.06666667
SH3GLB1 ENSG00000097033 51100 Cytoplasm 0.007692308 9.0 15.36713 0.11111111
ULK1 ENSG00000177169 8408 Cytoplasm 0.007194245 26.0 49.47304 0.07384615
BECN1 ENSG00000126581 8678 Cytoplasm/Nucleus 0.007142857 18.0 49.29796 0.11764706
BMI1 ENSG00000168283 648 Cytoplasm/Nucleus 0.007194245 10.0 2.788651 0.24444444
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 0.008403361 36.0 70.74902 0.04126984
CDKN2A ENSG00000147889 1029 Cytoplasm/Nucleus 0.007936508 30.0 44.87196 0.03678161
CEBPB ENSG00000172216 1051 Cytoplasm/Nucleus 0.007874016 21.0 31.60791 0.08095238
CREG1 ENSG00000143162 8804 Cytoplasm/Nucleus 0.005813953 3.0 1.475386 0.0
CYFIP1 ENSG00000273749 23191 Cytoplasm/Nucleus 0.006451613 3.0 4.222668 0.0
FKBP8 ENSG00000105701 23770 Cytoplasm/Nucleus 0.006329114 4.0 5.65252 0.16666667
MAP2K3 ENSG00000034152 5606 Cytoplasm/Nucleus 0.006711409 16.0 4.046502 0.05
MDM2 ENSG00000135679 4193 Cytoplasm/Nucleus 0.008264463 56.0 58.76684 0.01558442
RB1CC1 ENSG00000023287 9821 Cytoplasm/Nucleus 0.007936508 19.0 95.19015 0.10526316
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 0.009174312 47.0 191.4686 0.0453284
TP53 ENSG00000141510 7157 Cytoplasm/Nucleus 0.010869565 95.0 475.7535 0.02194849
CD44 ENSG00000026508 960 Membrane 0.008333333 18.0 53.98358 0.13071895
HRAS ENSG00000174775 3265 Membrane 0.008264463 81.0 39.89653 0.01141975
IGF1R ENSG00000140443 3480 Membrane 0.007751938 32.0 15.81889 0.04032258
IL6R ENSG00000160712 3570 Membrane 0.006622517 8.0 2.15712 0.14285714
PLAU ENSG00000122861 5328 Membrane 0.006944444 13.0 13.14254 0.07692308
RAF1 ENSG00000132155 5894 Membrane 0.008333333 53.0 31.8437 0.01814224
SLC39A1 ENSG00000143570 27173 Membrane 0.00621118 3.0 4.476348 0.33333333
SLC39A2 ENSG00000165794 29986 Membrane 0.005882353 2.0 0.0 1.0
SLC39A4 ENSG00000147804 55630 Membrane 0.005813953 1.0 0.0 0.0
AMBRA1 ENSG00000110497 55626 Unknown 0.00591716 11.0 0.0 0.10909091
ATG13 ENSG00000175224 9776 Unknown 0.00625 17.0 3.443014 0.13970588
CXCL14 ENSG00000145824 9547 Unknown 0.005747126 2.0 0.0 1.0
CXCL8 ENSG00000169429 3576 Unknown 0.006896552 12.0 13.80174 0.13636364
FN1 ENSG00000115414 2335 Unknown 0.00862069 29.0 81.88734 0.13300493
GABARAPL1 ENSG00000139112 23710 Unknown 0.006849315 13.0 27.18714 0.25641026
GSK3B ENSG00000082701 2932 Unknown 0.007518797 22.0 6.569019 0.08225108
KMT2A ENSG00000118058 4297 Unknown 0.007194245 7.0 3.291429 0.38095238
MAP1LC3A ENSG00000101460 84557 Unknown 0.007751938 13.0 31.01047 0.28205128
MAPK14 ENSG00000112062 1432 Unknown 0.009259259 43.0 192.8612 0.04761905
SLC39A3 ENSG00000141873 29985 Unknown 0.005813953 1.0 0.0 0.0
SQSTM1 ENSG00000161011 8878 Unknown 0.008928571 19.0 315.9564 0.11111111
ZMYND8 ENSG00000101040 23613 Unknown 0.005952381 1.0 0.0 0.0
IFI16 ENSG00000163565 3428 Nucleus 0.007751938 8.0 22.59069 0.32142857
ING1 ENSG00000153487 3621 Nucleus 0.006944444 6.0 0.1681746 0.26666667
ING2 ENSG00000168556 3622 Nucleus 0.006578947 2.0 0.0 0.0
RB1 ENSG00000139687 5925 Nucleus 0.00862069 34.0 129.1523 0.04812834
COL1A1 ENSG00000108821 1277 Secreted 0.007751938 17.0 26.38345 0.15441176
COL3A1 ENSG00000168542 1281 Secreted 0.006802721 8.0 3.017301 0.39285714
CXCL1 ENSG00000163739 2919 Secreted 0.006024096 2.0 0.03225806 0.0
IL6 ENSG00000136244 3569 Secreted 0.007407407 20.0 33.25143 0.06315789
INS ENSG00000254647 3630 Secreted 0.008474576 29.0 91.72319 0.08128079
LAMA3 ENSG00000053747 3909 Secreted 0.007142857 9.0 9.41114 0.38888889
PLAT ENSG00000104368 5327 Secreted 0.006369427 11.0 8.492965 0.09090909
SERPINE1 ENSG00000106366 5054 Secreted 0.007518797 21.0 53.30031 0.04761905
SPARC ENSG00000113140 6678 Secreted 0.006369427 7.0 3.175819 0.23809524
IGFBP3 ENSG00000146674 3486 Secreted/Nucleus 0.007246377 15.0 7.941842 0.11428571
IGFBP5 ENSG00000115461 3488 Secreted/Nucleus 0.006410256 9.0 2.628295 0.11111111
IL1B ENSG00000125538 3553 Secreted/Nucleus 0.00877193 29.0 61.01253 0.08128079
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
AKT1S1 ENSG00000204673 84335 Cytoplasm 317.0 349.0 1.55E-6 0.00837
ATG7 ENSG00000197548 10533 Cytoplasm 65.0 5940.0 1.54E-6 0.0284
BRAF ENSG00000157764 673 Cytoplasm 12094.0 42600.0 1.56E-6 4.04E-5
GABARAPL2 ENSG00000034713 11345 Cytoplasm 103.0 4030.0 1.53E-6 0.0419
GSN ENSG00000148180 2934 Cytoplasm 235.0 5670.0 1.56E-6 0.0452
IGF1 ENSG00000017427 3479 Cytoplasm 1260.0 84400.0 1.56E-6 0.00215
IKBKE ENSG00000263528 9641 Cytoplasm 626.0 10500.0 1.55E-6 0.00645
MLST8 ENSG00000167965 64223 Cytoplasm 569.0 1650.0 1.55E-6 0.00434
SERPINB2 ENSG00000197632 5055 Cytoplasm 30.0 4520.0 1.54E-6 0.0276
SH3GLB1 ENSG00000097033 51100 Cytoplasm 49.0 32.5 1.55E-6 0.123
ULK1 ENSG00000177169 8408 Cytoplasm 182.0 7270.0 1.54E-6 0.0263
BECN1 ENSG00000126581 8678 Cytoplasm/Nucleus 131.0 9680.0 1.54E-6 0.0339
BMI1 ENSG00000168283 648 Cytoplasm/Nucleus 200.0 1490.0 1.55E-6 0.179
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 3911.0 109000.0 1.56E-6 8.1E-4
CDKN2A ENSG00000147889 1029 Cytoplasm/Nucleus 1709.0 38000.0 1.56E-6 0.00396
CEBPB ENSG00000172216 1051 Cytoplasm/Nucleus 740.0 78400.0 1.56E-6 0.0187
CREG1 ENSG00000143162 8804 Cytoplasm/Nucleus 3.0 0.0478 1.54E-6 0.0
CYFIP1 ENSG00000273749 23191 Cytoplasm/Nucleus 280.0 1700.0 1.55E-6 0.1
FKBP8 ENSG00000105701 23770 Cytoplasm/Nucleus 20.0 1.02 1.54E-6 0.0789
MAP2K3 ENSG00000034152 5606 Cytoplasm/Nucleus 2871.0 8580.0 1.56E-6 3.52E-4
MDM2 ENSG00000135679 4193 Cytoplasm/Nucleus 2666.0 363000.0 1.56E-6 0.00187
RB1CC1 ENSG00000023287 9821 Cytoplasm/Nucleus 94.0 4330.0 1.55E-6 0.101
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 14851.0 1350000.0 1.57E-6 2.68E-4
TP53 ENSG00000141510 7157 Cytoplasm/Nucleus 8418.0 2450000.0 1.57E-6 7.36E-4
CD44 ENSG00000026508 960 Membrane 658.0 66200.0 1.56E-6 0.0285
HRAS ENSG00000174775 3265 Membrane 21752.0 305000.0 1.56E-6 6.79E-5
IGF1R ENSG00000140443 3480 Membrane 2050.0 25200.0 1.56E-6 0.00201
IL6R ENSG00000160712 3570 Membrane 796.0 333.0 1.55E-6 0.015
PLAU ENSG00000122861 5328 Membrane 359.0 26400.0 1.55E-6 0.00643
RAF1 ENSG00000132155 5894 Membrane 23706.0 140000.0 1.56E-6 1.64E-5
SLC39A1 ENSG00000143570 27173 Membrane 4.0 54.3 1.53E-6 0.167
SLC39A2 ENSG00000165794 29986 Membrane 3.0 0.0 1.53E-6 0.333
SLC39A4 ENSG00000147804 55630 Membrane 1.0 0.0 1.53E-6 0.0
AMBRA1 ENSG00000110497 55626 Unknown 85.0 1860.0 1.54E-6 0.0569
ATG13 ENSG00000175224 9776 Unknown 93.0 812.0 1.54E-6 0.0986
CXCL14 ENSG00000145824 9547 Unknown 76.0 39.6 1.54E-6 0.00877
CXCL8 ENSG00000169429 3576 Unknown 1129.0 129000.0 1.56E-6 0.0124
FN1 ENSG00000115414 2335 Unknown 2115.0 124000.0 1.56E-6 0.00399
GABARAPL1 ENSG00000139112 23710 Unknown 105.0 16100.0 1.54E-6 0.0322
GSK3B ENSG00000082701 2932 Unknown 9387.0 367000.0 1.56E-6 1.84E-4
KMT2A ENSG00000118058 4297 Unknown 63.0 650.0 1.55E-6 0.32
MAP1LC3A ENSG00000101460 84557 Unknown 86.0 23500.0 1.55E-6 0.0596
MAPK14 ENSG00000112062 1432 Unknown 9287.0 427000.0 1.56E-6 2.57E-4
SLC39A3 ENSG00000141873 29985 Unknown 1.0 0.0 1.53E-6 0.0
SQSTM1 ENSG00000161011 8878 Unknown 321.0 57400.0 1.55E-6 0.0137
ZMYND8 ENSG00000101040 23613 Unknown 7.0 0.0404 1.55E-6 0.571
IFI16 ENSG00000163565 3428 Nucleus 24.0 215.0 1.55E-6 0.127
ING1 ENSG00000153487 3621 Nucleus 6.0 0.00305 1.54E-6 0.267
ING2 ENSG00000168556 3622 Nucleus 14.0 1.15 1.55E-6 0.297
RB1 ENSG00000139687 5925 Nucleus 4373.0 218000.0 1.56E-6 0.00126
COL1A1 ENSG00000108821 1277 Secreted 844.0 26400.0 1.55E-6 0.0188
COL3A1 ENSG00000168542 1281 Secreted 695.0 9890.0 1.55E-6 0.0271
CXCL1 ENSG00000163739 2919 Secreted 168.0 138.0 1.55E-6 0.0471
IL6 ENSG00000136244 3569 Secreted 1764.0 36100.0 1.56E-6 0.00384
INS ENSG00000254647 3630 Secreted 1834.0 510000.0 1.56E-6 0.00309
LAMA3 ENSG00000053747 3909 Secreted 895.0 17000.0 1.55E-6 0.0101
PLAT ENSG00000104368 5327 Secreted 426.0 1770.0 1.54E-6 7.73E-4
SERPINE1 ENSG00000106366 5054 Secreted 269.0 23500.0 1.55E-6 0.00946
SPARC ENSG00000113140 6678 Secreted 29.0 303.0 1.55E-6 0.15
IGFBP3 ENSG00000146674 3486 Secreted/Nucleus 78.0 17600.0 1.55E-6 0.03
IGFBP5 ENSG00000115461 3488 Secreted/Nucleus 33.0 150.0 1.54E-6 0.0473
IL1B ENSG00000125538 3553 Secreted/Nucleus 2345.0 54300.0 1.56E-6 0.00173
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
AKT1S1 ENSG00000204673 84335 Cytoplasm 42.0 72.0 2.14E-5 0.084785134
ATG7 ENSG00000197548 10533 Cytoplasm 11.0 0.0 2.05E-5 0.109090909
BRAF ENSG00000157764 673 Cytoplasm 520.0 6510.0 2.15E-5 0.003282941
GABARAPL2 ENSG00000034713 11345 Cytoplasm 11.0 6.58 2.05E-5 0.290909091
GSN ENSG00000148180 2934 Cytoplasm 8.0 0.0685 2.11E-5 0.285714286
IGF1 ENSG00000017427 3479 Cytoplasm 64.0 825.0 2.12E-5 0.021825397
IKBKE ENSG00000263528 9641 Cytoplasm 25.0 259.0 2.12E-5 0.08
MLST8 ENSG00000167965 64223 Cytoplasm 19.0 1060.0 2.11E-5 0.087719298
SERPINB2 ENSG00000197632 5055 Cytoplasm 10.0 300.0 2.08E-5 0.066666667
SH3GLB1 ENSG00000097033 51100 Cytoplasm 9.0 28.8 2.1E-5 0.111111111
ULK1 ENSG00000177169 8408 Cytoplasm 26.0 266.0 2.08E-5 0.073846154
BECN1 ENSG00000126581 8678 Cytoplasm/Nucleus 18.0 1590.0 2.09E-5 0.117647059
BMI1 ENSG00000168283 648 Cytoplasm/Nucleus 10.0 22.8 2.11E-5 0.244444444
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 647.0 16600.0 2.16E-5 0.003363942
CDKN2A ENSG00000147889 1029 Cytoplasm/Nucleus 159.0 389.0 2.13E-5 0.005572805
CEBPB ENSG00000172216 1051 Cytoplasm/Nucleus 73.0 3530.0 2.14E-5 0.036149163
CREG1 ENSG00000143162 8804 Cytoplasm/Nucleus 3.0 6.56 2.07E-5 0.0
CYFIP1 ENSG00000273749 23191 Cytoplasm/Nucleus 5.0 138.0 2.09E-5 0.0
FKBP8 ENSG00000105701 23770 Cytoplasm/Nucleus 4.0 0.758 2.09E-5 0.166666667
MAP2K3 ENSG00000034152 5606 Cytoplasm/Nucleus 249.0 7210.0 2.15E-5 0.011594766
MDM2 ENSG00000135679 4193 Cytoplasm/Nucleus 531.0 6780.0 2.15E-5 0.003105568
RB1CC1 ENSG00000023287 9821 Cytoplasm/Nucleus 19.0 2060.0 2.1E-5 0.105263158
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 1835.0 67000.0 2.17E-5 0.001945688
TP53 ENSG00000141510 7157 Cytoplasm/Nucleus 1691.0 145000.0 2.18E-5 0.001606136
CD44 ENSG00000026508 960 Membrane 32.0 489.0 2.13E-5 0.102822581
HRAS ENSG00000174775 3265 Membrane 1733.0 25200.0 2.17E-5 0.001844377
IGF1R ENSG00000140443 3480 Membrane 104.0 3510.0 2.14E-5 0.021284541
IL6R ENSG00000160712 3570 Membrane 32.0 2.48 2.11E-5 0.084677419
PLAU ENSG00000122861 5328 Membrane 49.0 1480.0 2.13E-5 0.065476191
RAF1 ENSG00000132155 5894 Membrane 1624.0 13700.0 2.15E-5 6.27525E-4
SLC39A1 ENSG00000143570 27173 Membrane 3.0 20.6 2.07E-5 0.333333333
SLC39A2 ENSG00000165794 29986 Membrane 2.0 0.0 2.05E-5 1.0
SLC39A4 ENSG00000147804 55630 Membrane 1.0 0.0 2.05E-5 0.0
AMBRA1 ENSG00000110497 55626 Unknown 11.0 0.0 2.03E-5 0.109090909
ATG13 ENSG00000175224 9776 Unknown 17.0 6.45 2.04E-5 0.139705882
CXCL14 ENSG00000145824 9547 Unknown 2.0 0.0 2.06E-5 1.0
CXCL8 ENSG00000169429 3576 Unknown 28.0 566.0 2.12E-5 0.097883598
FN1 ENSG00000115414 2335 Unknown 42.0 2530.0 2.13E-5 0.092915215
GABARAPL1 ENSG00000139112 23710 Unknown 13.0 53.9 2.06E-5 0.256410256
GSK3B ENSG00000082701 2932 Unknown 1280.0 52400.0 2.17E-5 9.82213E-4
KMT2A ENSG00000118058 4297 Unknown 7.0 6.79 2.1E-5 0.380952381
MAP1LC3A ENSG00000101460 84557 Unknown 13.0 597.0 2.1E-5 0.282051282
MAPK14 ENSG00000112062 1432 Unknown 1219.0 74200.0 2.17E-5 0.002559367
SLC39A3 ENSG00000141873 29985 Unknown 1.0 0.0 2.05E-5 0.0
SQSTM1 ENSG00000161011 8878 Unknown 48.0 11000.0 2.13E-5 0.093971631
ZMYND8 ENSG00000101040 23613 Unknown 7.0 1.59 2.1E-5 0.523809524
IFI16 ENSG00000163565 3428 Nucleus 8.0 62.5 2.1E-5 0.321428571
ING1 ENSG00000153487 3621 Nucleus 6.0 0.0829 2.1E-5 0.266666667
ING2 ENSG00000168556 3622 Nucleus 2.0 0.0 2.09E-5 0.0
RB1 ENSG00000139687 5925 Nucleus 496.0 18100.0 2.16E-5 0.005865103
COL1A1 ENSG00000108821 1277 Secreted 31.0 4260.0 2.12E-5 0.07311828
COL3A1 ENSG00000168542 1281 Secreted 16.0 207.0 2.1E-5 0.2
CXCL1 ENSG00000163739 2919 Secreted 2.0 0.00648 2.09E-5 0.0
IL6 ENSG00000136244 3569 Secreted 163.0 6750.0 2.14E-5 0.011436795
INS ENSG00000254647 3630 Secreted 135.0 8260.0 2.14E-5 0.017025981
LAMA3 ENSG00000053747 3909 Secreted 9.0 24.1 2.1E-5 0.388888889
PLAT ENSG00000104368 5327 Secreted 60.0 439.0 2.1E-5 0.007344633
SERPINE1 ENSG00000106366 5054 Secreted 82.0 5990.0 2.12E-5 0.009936766
SPARC ENSG00000113140 6678 Secreted 14.0 110.0 2.07E-5 0.131868132
IGFBP3 ENSG00000146674 3486 Secreted/Nucleus 15.0 46.2 2.1E-5 0.114285714
IGFBP5 ENSG00000115461 3488 Secreted/Nucleus 13.0 9.91 2.07E-5 0.051282051
IL1B ENSG00000125538 3553 Secreted/Nucleus 271.0 11900.0 2.15E-5 0.00932076
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
AMBRA1 BECN1 7
ATG13 BECN1 1
ATG13 RB1CC1 6
ATG13 ULK1 6
ATG7 GABARAPL1 4
ATG7 GABARAPL2 6
ATG7 MAP1LC3A 3
BECN1 GABARAPL1 1
BECN1 GABARAPL2 1
BECN1 MAP1LC3A 1
BMI1 CDKN2A 2
BMI1 KMT2A 3
BRAF HRAS 7
BRAF MAP2K3 2
BRAF RAF1 9
CD44 COL1A1 3
CD44 FN1 2
CD44 SRC 2
CDKN1A RB1 5
CDKN2A CDKN1A 2
CDKN2A MDM2 9
CDKN2A RB1 2
CDKN2A TP53 4
CEBPB CXCL8 3
CEBPB IL6 2
COL1A1 FN1 6
COL1A1 SPARC 3
COL3A1 SPARC 4
FKBP8 MLST8 2
FN1 IGF1 2
FN1 SRC 3
GSK3B CEBPB 1
GSK3B HRAS 1
GSK3B MDM2 2
GSK3B TP53 8
HRAS RAF1 14
IFI16 TP53 5
IGF1 GSK3B 1
IGF1 IGF1R 12
IGF1 IGFBP3 8
IGF1 IGFBP5 7
IGF1 RB1 1
IGF1R HRAS 2
IGF1R INS 3
IL1B CXCL8 1
IL1B IL6 1
IL1B MAPK14 2
IL1B SRC 1
IL1B TP53 2
IL6 IL6R 12
ING1 TP53 4
INS GSK3B 1
INS RB1 3
MAP1LC3A SQSTM1 3
MAP2K3 MAPK14 12
MAPK14 BMI1 1
MAPK14 CDKN1A 1
MAPK14 CDKN2A 2
MAPK14 CEBPB 1
MAPK14 GSK3B 1
MAPK14 RB1 3
MAPK14 TP53 8
MDM2 RB1 7
MDM2 TP53 12
MLST8 ULK1 3
PLAT PLAU 3
PLAT SERPINE1 5
PLAU SERPINB2 4
PLAU SERPINE1 7
PLAU SRC 1
RAF1 MAP2K3 1
RAF1 RB1 5
RAF1 SRC 5
RB1CC1 AMBRA1 1
RB1CC1 BECN1 1
RB1CC1 TP53 3
RB1CC1 ULK1 6
RB1 SERPINB2 4
SRC BRAF 1
SRC GSN 2
SRC HRAS 4
SRC MAPK14 2
SRC MDM2 1
SRC SH3GLB1 2
TP53 CDKN1A 6
TP53 IGFBP3 3
TP53 SERPINE1 3
ULK1 BECN1 1
AKT1S1 MLST8 3
AKT1S1 SQSTM1 1
AKT1S1 TP53 1
AMBRA1 ATG13 3
AMBRA1 ULK1 3
ATG13 GABARAPL1 2
ATG13 GABARAPL2 2
ATG13 MAP1LC3A 3
ATG13 MLST8 2
ATG7 SQSTM1 1
BECN1 SH3GLB1 1
BECN1 SRC 1
BMI1 MDM2 2
BMI1 TP53 1
BRAF FN1 1
BRAF LAMA3 1
BRAF MAPK14 1
CD44 IGFBP3 2
CD44 PLAU 1
CD44 RB1 1
CD44 SQSTM1 1
CD44 TP53 1
CDKN1A BMI1 1
CDKN1A GSK3B 2
CDKN1A IL1B 1
CDKN1A MDM2 4
CDKN2A FN1 1
CDKN2A IKBKE 1
CDKN2A ING1 1
CEBPB IGFBP5 1
CEBPB ING1 1
CEBPB MAP2K3 1
CEBPB RB1 3
CEBPB SERPINE1 1
CEBPB TP53 1
COL1A1 COL3A1 1
COL1A1 IGFBP3 2
COL1A1 LAMA3 1
COL1A1 SRC 1
COL1A1 TP53 2
COL3A1 CD44 1
COL3A1 FN1 2
COL3A1 LAMA3 1
COL3A1 SRC 1
CREG1 CYFIP1 1
CREG1 RB1 2
CXCL1 CDKN1A 1
CXCL1 HRAS 1
CXCL8 CDKN1A 1
CXCL8 CXCL14 1
CXCL8 IL6 1
CXCL8 IL6R 2
FKBP8 IKBKE 1
FKBP8 MAPK14 2
FN1 GSN 2
FN1 HRAS 1
FN1 IGF1R 1
FN1 IGFBP3 2
FN1 IGFBP5 1
FN1 LAMA3 1
FN1 PLAT 1
FN1 PLAU 1
FN1 RAF1 1
FN1 SH3GLB1 1
FN1 SPARC 1
FN1 TP53 2
GABARAPL1 GABARAPL2 2
GABARAPL1 MAP1LC3A 1
GABARAPL1 RB1CC1 1
GABARAPL1 SERPINB2 1
GABARAPL1 SQSTM1 3
GABARAPL1 ULK1 2
GABARAPL2 MAP1LC3A 2
GABARAPL2 SQSTM1 4
GABARAPL2 ULK1 4
GSN MDM2 1
GSN TP53 1
HRAS GSN 1
HRAS MAPK14 1
HRAS RB1 1
HRAS TP53 1
IFI16 CDKN1A 1
IFI16 CYFIP1 1
IFI16 KMT2A 2
IFI16 MDM2 1
IFI16 RB1 1
IFI16 SQSTM1 1
IGF1 CDKN1A 1
IGF1 HRAS 1
IGF1R IGFBP3 2
IGF1R MDM2 4
IGF1R TP53 1
IGFBP3 IGFBP5 1
IGFBP5 SERPINE1 2
IKBKE AKT1S1 1
IKBKE ULK1 1
IL1B CEBPB 1
IL1B COL1A1 1
IL1B GSK3B 1
IL1B IL6R 1
IL1B INS 1
IL1B SERPINE1 1
IL1B SQSTM1 1
IL6 COL1A1 1
IL6R SRC 1
IL6 SLC39A1 1
ING1 MDM2 1
ING2 TP53 3
INS CXCL14 1
INS CXCL8 1
INS FN1 1
INS HRAS 1
INS IL6 1
INS KMT2A 1
INS MAPK14 1
INS SRC 1
INS TP53 1
KMT2A MDM2 1
KMT2A SERPINE1 1
KMT2A TP53 1
LAMA3 CD44 1
LAMA3 MAP2K3 1
LAMA3 PLAT 2
LAMA3 RB1 1
MAP1LC3A RB1CC1 2
MAP1LC3A ULK1 3
MAPK14 SQSTM1 1
MDM2 ULK1 2
MLST8 IKBKE 1
MLST8 RB1CC1 2
MLST8 SQSTM1 1
PLAT SPARC 1
RAF1 LAMA3 1
RAF1 MAPK14 1
RAF1 RB1CC1 2
RAF1 SERPINE1 1
RAF1 TP53 2
RB1CC1 CDKN1A 1
RB1 SH3GLB1 1
RB1 TP53 3
SERPINB2 PLAT 1
SERPINE1 INS 1
SH3GLB1 IGF1R 1
SH3GLB1 SQSTM1 1
SLC39A1 SLC39A2 1
SPARC INS 1
SQSTM1 SLC39A1 1
SQSTM1 SLC39A2 1
SQSTM1 SLC39A3 1
SQSTM1 SLC39A4 1
SQSTM1 TP53 1
SQSTM1 ULK1 3
SRC CYFIP1 1
SRC IGF1 1
SRC IGF1R 1
SRC TP53 2
TP53 BRAF 1
TP53 IL6 1
TP53 MAP1LC3A 1
ZMYND8 MAPK14 1
Pathway1 Pathway2 Intersect Similarity Scores Pathway Name Source Number of Genes Number of Interactions Detail
pathway0002722 pathway0002807 4 0.8 Hs_Retinoblastoma_(RB)_in_Cancer_WP2446_87639 WikiPathways 5 8