Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0002798 Hs_AMP-activated_Protein_Kinase_(AMPK)_Signaling_WP1403_90259 WikiPathways Homo sapiens 11 15
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
EEF2K ENSG00000103319 29904 Cytoplasm 0.04347826 6.0 25.0 0.06666667
HMGCR ENSG00000113161 3156 Cytoplasm 0.02941176 4.0 9.0 0.16666667
CCNB1 ENSG00000134057 891 Cytoplasm/Nucleus 0.04 4.0 12.0 0.33333333
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 0.03448276 4.0 16.0 0.16666667
CRTC2 ENSG00000160741 200186 Cytoplasm/Nucleus 0.02777778 2.0 9.0 0.0
EEF2 ENSG00000167658 1938 Cytoplasm/Nucleus 0.04166667 6.0 24.0 0.06666667
ELAVL1 ENSG00000066044 1994 Cytoplasm/Nucleus 0.04 3.0 6.0 0.66666667
FASN ENSG00000169710 2194 Cytoplasm/Nucleus 0.03571429 5.0 4.666667 0.2
PGM5 ENSG00000154330 5239 Membrane 0.02325581 1.0 0.0 0.0
SREBF1 ENSG00000072310 6720 Unknown 0.03571429 8.0 9.333333 0.07142857
PPARGC1B ENSG00000155846 133522 Nucleus 0.02222222 1.0 0.0 0.0
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
EEF2K ENSG00000103319 29904 Cytoplasm 56.0 93.01618 1.54E-6 0.015584416
HMGCR ENSG00000113161 3156 Cytoplasm 226.0 13727.89 1.55E-6 0.00979351
CCNB1 ENSG00000134057 891 Cytoplasm/Nucleus 1271.0 37902.72 1.56E-6 0.014490419
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 3911.0 108578.1 1.56E-6 8.10489E-4
CRTC2 ENSG00000160741 200186 Cytoplasm/Nucleus 31.0 41.71933 1.54E-6 0.107526882
EEF2 ENSG00000167658 1938 Cytoplasm/Nucleus 128.0 72494.61 1.55E-6 0.295890748
ELAVL1 ENSG00000066044 1994 Cytoplasm/Nucleus 210.0 21838.94 1.55E-6 0.390931875
FASN ENSG00000169710 2194 Cytoplasm/Nucleus 120.0 38368.23 1.55E-6 0.017647059
PGM5 ENSG00000154330 5239 Membrane 1.0 0.0 1.52E-6 0.0
SREBF1 ENSG00000072310 6720 Unknown 309.0 119059.6 1.55E-6 0.016475434
PPARGC1B ENSG00000155846 133522 Nucleus 16.0 1351.87 1.54E-6 0.041666667
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
EEF2K ENSG00000103319 29904 Cytoplasm 6.0 3.75 2.06E-5 0.066666667
HMGCR ENSG00000113161 3156 Cytoplasm 7.0 2000.0 2.1E-5 0.095238095
CCNB1 ENSG00000134057 891 Cytoplasm/Nucleus 33.0 565.0 2.12E-5 0.121212121
CDKN1A ENSG00000124762 1026 Cytoplasm/Nucleus 647.0 16600.0 2.16E-5 0.003363942
CRTC2 ENSG00000160741 200186 Cytoplasm/Nucleus 2.0 0.471 2.08E-5 0.0
EEF2 ENSG00000167658 1938 Cytoplasm/Nucleus 14.0 1070.0 2.12E-5 0.175824176
ELAVL1 ENSG00000066044 1994 Cytoplasm/Nucleus 18.0 1230.0 2.12E-5 0.130718954
FASN ENSG00000169710 2194 Cytoplasm/Nucleus 17.0 555.0 2.08E-5 0.029411765
PGM5 ENSG00000154330 5239 Membrane 1.0 0.0 2.02E-5 0.0
SREBF1 ENSG00000072310 6720 Unknown 47.0 3440.0 2.09E-5 0.012025902
PPARGC1B ENSG00000155846 133522 Nucleus 5.0 1960.0 2.1E-5 0.0
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
CCNB1 CDKN1A 5
SREBF1 FASN 2
CCNB1 EEF2K 1
CDKN1A CRTC2 1
CRTC2 PPARGC1B 1
EEF2 EEF2K 2
EEF2 FASN 1
EEF2K ELAVL1 1
ELAVL1 CCNB1 1
ELAVL1 CDKN1A 1
HMGCR FASN 1
HMGCR PGM5 1
HMGCR SREBF1 1
SREBF1 EEF2 1
Pathway1 Pathway2 Intersect Similarity Scores Pathway Name Source Number of Genes Number of Interactions Detail