Pathway ID Pathway Name Source Organism Number of Genes Number of Interactions
pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways Homo sapiens 107 1336
Secreted
Membrane
Cytoplasm
Cytoplasm/4
Cytoskeleton
Cytoskeleton/Cytoplasm
Membrane/Nucleus
Cytoplasm/Nucleus
Cytoskeleton/Nucleus
Nucleus
Secreted/Nucleus
Unknown
Annotated genes
Unannotated genes
Symbol
Ensembl ID
Entrez ID
Subcellular localization
Description
Type
Edge
Symbol Ensembl ID Entrez ID Subcellular localization Closeness Degree Betweenness Transitivity
ABI1 ENSG00000136754 10006 Cytoplasm 0.005376344 36.0 4.07 0.36031746
ARF6 ENSG00000165527 382 Cytoplasm 0.005102041 29.0 13.5 0.22660099
ASAP1 ENSG00000153317 50807 Cytoplasm 0.004651163 21.0 7.36 0.19047619
BRAF ENSG00000157764 673 Cytoplasm 0.005347594 144.0 9.71 0.0208819
CBLC ENSG00000142273 23624 Cytoplasm 0.004694836 19.0 2.31 0.23391813
CSK ENSG00000103653 1445 Cytoplasm 0.005434783 49.0 4.38 0.20578231
DNM1 ENSG00000106976 1759 Cytoplasm 0.004950495 20.0 11.9 0.23157895
GAB1 ENSG00000109458 2549 Cytoplasm 0.005780347 104.0 31.1 0.08812547
GAB2 ENSG00000033327 9846 Cytoplasm 0.00591716 92.0 42.8 0.1158624
GRB10 ENSG00000106070 2887 Cytoplasm 0.004878049 22.0 1.08 0.22943723
INPP5D ENSG00000168918 3635 Cytoplasm 0.005263158 57.0 5.27 0.14786967
JAK1 ENSG00000162434 3716 Cytoplasm 0.00591716 134.0 34.3 0.06127258
KRAS ENSG00000133703 3845 Cytoplasm 0.00591716 187.0 60.0 0.02484043
MAP4K1 ENSG00000104814 11184 Cytoplasm 0.004807692 13.0 0.435 0.33333333
NEDD4 ENSG00000069869 4734 Cytoplasm 0.004950495 17.0 5.07 0.25735294
PEBP1 ENSG00000089220 5037 Cytoplasm 0.004878049 30.0 1.34 0.14022989
PLCE1 ENSG00000138193 51196 Cytoplasm 0.004444444 18.0 0.0878 0.15686275
PRKCD ENSG00000163932 5580 Cytoplasm 0.005780347 81.0 35.0 0.12839506
PTPN11 ENSG00000179295 5781 Cytoplasm 0.005649718 124.0 8.73 0.05586153
PTPN5 ENSG00000110786 84867 Cytoplasm 0.004115226 7.0 0.00341 0.23809524
RALB ENSG00000144118 5899 Cytoplasm 0.004739336 19.0 7.26 0.12865497
RALGDS ENSG00000160271 5900 Cytoplasm 0.004545455 23.0 2.35 0.07509881
SH2D2A ENSG00000027869 9047 Cytoplasm 0.005025126 29.0 2.46 0.30541872
SOS1 ENSG00000115904 6654 Cytoplasm 0.005952381 181.0 29.9 0.03480663
SOS2 ENSG00000100485 6655 Cytoplasm 0.005405405 109.0 2.6 0.05045872
STMN1 ENSG00000117632 3925 Cytoplasm 0.00456621 11.0 0.407 0.21818182
STXBP1 ENSG00000136854 6812 Cytoplasm 0.004219409 5.0 0.523 0.5
TNK2 ENSG00000061938 10188 Cytoplasm 0.004716981 12.0 1.62 0.46969697
USP6NL ENSG00000148429 9712 Cytoplasm 0.004291845 9.0 0.0758 0.13888889
CBL ENSG00000110395 867 Cytoplasm/Nucleus 0.005813953 87.0 54.9 0.10264635
CFL1 ENSG00000172757 1072 Cytoplasm/Nucleus 0.004950495 24.0 10.9 0.12681159
CRK ENSG00000167193 1398 Cytoplasm/Nucleus 0.005813953 80.0 50.4 0.11772152
E2F1 ENSG00000101412 1869 Cytoplasm/Nucleus 0.005681818 46.0 123.0 0.19516908
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 0.004651163 31.0 2.22 0.03655914
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 0.005347594 69.0 52.0 0.04560955
EPS8 ENSG00000151491 2059 Cytoplasm/Nucleus 0.004926108 28.0 7.84 0.24867725
FOS ENSG00000170345 2353 Cytoplasm/Nucleus 0.005376344 66.0 12.8 0.09463869
FOXO4 ENSG00000184481 4303 Cytoplasm/Nucleus 0.004950495 31.0 20.8 0.09247312
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 0.005847953 142.0 35.5 0.05134352
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 0.00621118 122.0 305.0 0.05094161
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 0.005319149 169.0 6.88 0.01937165
MAP2K5 ENSG00000137764 5607 Cytoplasm/Nucleus 0.004784689 46.0 2.44 0.06956522
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 0.006410256 271.0 394.0 0.01653683
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 0.004545455 8.0 0.251 0.39285714
MAPK7 ENSG00000166484 5598 Cytoplasm/Nucleus 0.005128205 60.0 16.6 0.06892655
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 0.006024096 130.0 137.0 0.05474061
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 0.005586592 94.0 53.7 0.05696637
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 0.005813953 71.0 78.0 0.13078471
NCK2 ENSG00000071051 8440 Cytoplasm/Nucleus 0.005 28.0 3.12 0.24074074
NCOA3 ENSG00000124151 8202 Cytoplasm/Nucleus 0.005102041 25.0 3.78 0.33333333
NEDD8 ENSG00000129559 4738 Cytoplasm/Nucleus 0.004784689 7.0 0.295 0.66666667
PCNA ENSG00000132646 5111 Cytoplasm/Nucleus 0.004807692 12.0 1.89 0.36363636
PIAS3 ENSG00000131788 10401 Cytoplasm/Nucleus 0.00456621 21.0 0.109 0.11904762
PLCG1 ENSG00000124181 5335 Cytoplasm/Nucleus 0.005747126 127.0 41.0 0.05561805
PRKCA ENSG00000154229 5578 Cytoplasm/Nucleus 0.005952381 130.0 187.0 0.05378652
PTK2B ENSG00000120899 2185 Cytoplasm/Nucleus 0.005464481 68.0 9.57 0.13520632
PTK6 ENSG00000101213 5753 Cytoplasm/Nucleus 0.004716981 17.0 0.0205 0.19117647
PTPN12 ENSG00000127947 5782 Cytoplasm/Nucleus 0.004854369 16.0 0.932 0.41666667
RPS6KA3 ENSG00000177189 6197 Cytoplasm/Nucleus 0.005319149 52.0 15.8 0.11312217
RPS6KA5 ENSG00000100784 9252 Cytoplasm/Nucleus 0.004716981 33.0 8.05 0.08522727
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 0.005347594 72.0 16.5 0.06533646
SH3GL2 ENSG00000107295 6456 Cytoplasm/Nucleus 0.004807692 24.0 11.6 0.0942029
SH3KBP1 ENSG00000147010 30011 Cytoplasm/Nucleus 0.005263158 43.0 22.4 0.14728682
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 0.006802721 214.0 303.0 0.03602299
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 0.00617284 150.0 70.0 0.05503356
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 0.00621118 143.0 86.2 0.06057323
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 0.00621118 134.0 63.7 0.07126024
VAV2 ENSG00000160293 7410 Cytoplasm/Nucleus 0.005405405 55.0 1.65 0.2013468
AKT1 ENSG00000142208 207 Membrane 0.006666667 256.0 262.0 0.02346814
ARHGEF1 ENSG00000076928 9138 Membrane 0.004587156 10.0 0.689 0.24444444
DOK2 ENSG00000147443 9046 Membrane 0.004878049 18.0 0.454 0.43137255
ERBB2 ENSG00000141736 2064 Membrane 0.006024096 110.0 79.5 0.09491243
HRAS ENSG00000174775 3265 Membrane 0.006711409 226.0 236.0 0.03126844
ITCH ENSG00000078747 83737 Membrane 0.004854369 15.0 2.44 0.20952381
MTOR ENSG00000198793 2475 Membrane 0.005434783 99.0 27.8 0.05236034
PIK3C2B ENSG00000133056 5287 Membrane 0.005291005 37.0 3.21 0.35585586
PIK3R1 ENSG00000145675 5295 Membrane 0.006060606 241.0 130.0 0.01881051
PLD2 ENSG00000129219 5338 Membrane 0.005128205 38.0 22.7 0.15504979
PLSCR1 ENSG00000188313 5359 Membrane 0.004926108 13.0 1.43 0.44871795
RAB5A ENSG00000144566 5868 Membrane 0.004784689 13.0 4.62 0.19230769
RAF1 ENSG00000132155 5894 Membrane 0.005524862 187.0 39.6 0.01587028
RALA ENSG00000006451 5898 Membrane 0.004901961 26.0 18.1 0.08
RALBP1 ENSG00000017797 10928 Membrane 0.004524887 14.0 3.28 0.07692308
RIN1 ENSG00000174791 9610 Membrane 0.00462963 12.0 1.74 0.1969697
EGFR ENSG00000146648 1956 Unknown 0.007194245 255.0 616.0 0.02667902
GRB2 ENSG00000177885 2885 Unknown 0.006535948 249.0 210.0 0.02082524
IQSEC1 ENSG00000144711 9922 Unknown 0.004484305 5.0 0.081 0.1
LIMK2 ENSG00000182541 3985 Unknown 0.004504505 19.0 3.61 0.03508772
MAP3K2 ENSG00000169967 10746 Unknown 0.004694836 33.0 2.95 0.12121212
MAP3K7 ENSG00000135341 6885 Unknown 0.005235602 56.0 21.5 0.08441558
MAPK14 ENSG00000112062 1432 Unknown 0.005747126 94.0 72.2 0.07732784
PAK1 ENSG00000149269 5058 Unknown 0.005813953 94.0 103.0 0.09059712
PDPK1 ENSG00000140992 5170 Unknown 0.005649718 105.0 21.6 0.07197802
PLD1 ENSG00000075651 5337 Unknown 0.005 29.0 17.5 0.2044335
PTK2 ENSG00000169398 5747 Unknown 0.005649718 109.0 55.4 0.06201155
PXDN ENSG00000130508 7837 Unknown 0.004065041 4.0 0.0 1.0
REPS2 ENSG00000169891 9185 Unknown 0.004739336 10.0 8.97 0.17777778
SH3GL3 ENSG00000140600 6457 Unknown 0.004464286 11.0 1.74 0.18181818
STAT3 ENSG00000168610 6774 Unknown 0.006451613 176.0 143.0 0.04642857
ATF1 ENSG00000123268 466 Nucleus 0.004672897 15.0 0.951 0.25714286
AURKA ENSG00000087586 6790 Nucleus 0.004761905 13.0 2.88 0.1025641
ELK4 ENSG00000158711 2005 Nucleus 0.004424779 21.0 0.223 0.08095238
JUND ENSG00000130522 3727 Nucleus 0.004716981 26.0 4.94 0.10153846
MAP3K3 ENSG00000198909 4215 Nucleus 0.005050505 37.0 3.91 0.17417417
MYBL2 ENSG00000101057 4605 Nucleus 0.004255319 3.0 0.0 1.0
RPS6KA1 ENSG00000117676 6195 Nucleus 0.005154639 48.0 4.54 0.09840426
SP1 ENSG00000185591 6667 Nucleus 0.005154639 33.0 16.8 0.20265152
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
ABI1 ENSG00000136754 10006 Cytoplasm 692.0 1690.0 1.56E-6 0.0183
ARF6 ENSG00000165527 382 Cytoplasm 533.0 72600.0 1.55E-6 0.00954
ASAP1 ENSG00000153317 50807 Cytoplasm 148.0 7150.0 1.55E-6 0.0306
BRAF ENSG00000157764 673 Cytoplasm 12094.0 42600.0 1.56E-6 4.04E-5
CBLC ENSG00000142273 23624 Cytoplasm 396.0 489.0 1.55E-6 0.0192
CSK ENSG00000103653 1445 Cytoplasm 1486.0 6920.0 1.56E-6 0.0035
DNM1 ENSG00000106976 1759 Cytoplasm 563.0 27300.0 1.55E-6 0.00808
GAB1 ENSG00000109458 2549 Cytoplasm 5755.0 15400.0 1.56E-6 6.23E-4
GAB2 ENSG00000033327 9846 Cytoplasm 4097.0 11500.0 1.56E-6 0.00119
GRB10 ENSG00000106070 2887 Cytoplasm 353.0 28.3 1.55E-6 0.0062
INPP5D ENSG00000168918 3635 Cytoplasm 2133.0 15300.0 1.55E-6 0.00195
JAK1 ENSG00000162434 3716 Cytoplasm 8612.0 95400.0 1.56E-6 2.71E-4
KRAS ENSG00000133703 3845 Cytoplasm 15339.0 61700.0 1.56E-6 8.92E-5
MAP4K1 ENSG00000104814 11184 Cytoplasm 354.0 333.0 1.55E-6 0.00728
NEDD4 ENSG00000069869 4734 Cytoplasm 236.0 9980.0 1.55E-6 0.0533
PEBP1 ENSG00000089220 5037 Cytoplasm 343.0 344.0 1.55E-6 0.011
PLCE1 ENSG00000138193 51196 Cytoplasm 1259.0 973.0 1.55E-6 0.00222
PRKCD ENSG00000163932 5580 Cytoplasm 4033.0 210000.0 1.56E-6 0.00131
PTPN11 ENSG00000179295 5781 Cytoplasm 9733.0 167000.0 1.56E-6 2.5E-4
PTPN5 ENSG00000110786 84867 Cytoplasm 35.0 5.91 1.54E-6 0.0269
RALB ENSG00000144118 5899 Cytoplasm 114.0 85.4 1.55E-6 0.0123
RALGDS ENSG00000160271 5900 Cytoplasm 242.0 81.6 1.55E-6 0.00463
SH2D2A ENSG00000027869 9047 Cytoplasm 389.0 19.6 1.55E-6 0.0233
SOS1 ENSG00000115904 6654 Cytoplasm 23511.0 177000.0 1.56E-6 6.54E-5
SOS2 ENSG00000100485 6655 Cytoplasm 6309.0 10000.0 1.56E-6 2.71E-4
STMN1 ENSG00000117632 3925 Cytoplasm 98.0 684.0 1.55E-6 0.0259
STXBP1 ENSG00000136854 6812 Cytoplasm 255.0 65900.0 1.55E-6 0.0293
TNK2 ENSG00000061938 10188 Cytoplasm 64.0 108.0 1.55E-6 0.0789
USP6NL ENSG00000148429 9712 Cytoplasm 43.0 3850.0 1.55E-6 0.0177
CBL ENSG00000110395 867 Cytoplasm/Nucleus 5209.0 92900.0 1.56E-6 8.8E-4
CFL1 ENSG00000172757 1072 Cytoplasm/Nucleus 377.0 8330.0 1.56E-6 0.00669
CRK ENSG00000167193 1398 Cytoplasm/Nucleus 4161.0 46800.0 1.56E-6 8.51E-4
E2F1 ENSG00000101412 1869 Cytoplasm/Nucleus 2673.0 379000.0 1.56E-6 0.00371
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 1189.0 11000.0 1.55E-6 4.81E-4
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 3468.0 49000.0 1.56E-6 3.9E-4
EPS8 ENSG00000151491 2059 Cytoplasm/Nucleus 167.0 297.0 1.55E-6 0.0355
FOS ENSG00000170345 2353 Cytoplasm/Nucleus 3623.0 68600.0 1.56E-6 7.3E-4
FOXO4 ENSG00000184481 4303 Cytoplasm/Nucleus 623.0 15900.0 1.56E-6 0.0097
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 9806.0 203000.0 1.56E-6 2.47E-4
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 12667.0 3720000.0 1.57E-6 4.67E-4
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 22859.0 10500.0 1.55E-6 9.5E-6
MAP2K5 ENSG00000137764 5607 Cytoplasm/Nucleus 762.0 218.0 1.55E-6 0.00185
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 33563.0 1130000.0 1.56E-6 2.83E-5
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 56.0 7.73 1.55E-6 0.0195
MAPK7 ENSG00000166484 5598 Cytoplasm/Nucleus 1164.0 3380.0 1.56E-6 0.00133
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 11158.0 360000.0 1.56E-6 1.42E-4
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 6317.0 61100.0 1.56E-6 1.86E-4
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 4967.0 1640000.0 1.57E-6 0.00195
NCK2 ENSG00000071051 8440 Cytoplasm/Nucleus 729.0 1900.0 1.55E-6 0.00678
NCOA3 ENSG00000124151 8202 Cytoplasm/Nucleus 654.0 57700.0 1.56E-6 0.042
NEDD8 ENSG00000129559 4738 Cytoplasm/Nucleus 33.0 101.0 1.55E-6 0.116
PCNA ENSG00000132646 5111 Cytoplasm/Nucleus 1202.0 34600.0 1.56E-6 0.00807
PIAS3 ENSG00000131788 10401 Cytoplasm/Nucleus 462.0 7230.0 1.56E-6 0.00912
PLCG1 ENSG00000124181 5335 Cytoplasm/Nucleus 11809.0 263000.0 1.56E-6 2.37E-4
PRKCA ENSG00000154229 5578 Cytoplasm/Nucleus 10261.0 710000.0 1.56E-6 2.96E-4
PTK2B ENSG00000120899 2185 Cytoplasm/Nucleus 2732.0 39900.0 1.56E-6 0.00291
PTK6 ENSG00000101213 5753 Cytoplasm/Nucleus 170.0 11300.0 1.55E-6 0.0173
PTPN12 ENSG00000127947 5782 Cytoplasm/Nucleus 83.0 92.7 1.55E-6 0.0717
RPS6KA3 ENSG00000177189 6197 Cytoplasm/Nucleus 1191.0 4530.0 1.56E-6 0.00146
RPS6KA5 ENSG00000100784 9252 Cytoplasm/Nucleus 627.0 4510.0 1.55E-6 0.00267
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 3539.0 54900.0 1.56E-6 3.46E-4
SH3GL2 ENSG00000107295 6456 Cytoplasm/Nucleus 425.0 13200.0 1.55E-6 0.0185
SH3KBP1 ENSG00000147010 30011 Cytoplasm/Nucleus 514.0 3750.0 1.55E-6 0.02
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 14851.0 1350000.0 1.57E-6 2.68E-4
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 9900.0 278000.0 1.56E-6 2.9E-4
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 7688.0 196000.0 1.56E-6 4.69E-4
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 6515.0 71100.0 1.56E-6 5.43E-4
VAV2 ENSG00000160293 7410 Cytoplasm/Nucleus 3851.0 27300.0 1.56E-6 0.00136
AKT1 ENSG00000142208 207 Membrane 52751.0 2150000.0 1.57E-6 1.74E-5
ARHGEF1 ENSG00000076928 9138 Membrane 228.0 960.0 1.55E-6 0.00653
DOK2 ENSG00000147443 9046 Membrane 277.0 32.3 1.55E-6 0.0101
ERBB2 ENSG00000141736 2064 Membrane 4475.0 103000.0 1.56E-6 0.00131
HRAS ENSG00000174775 3265 Membrane 21752.0 305000.0 1.56E-6 6.79E-5
ITCH ENSG00000078747 83737 Membrane 729.0 33800.0 1.56E-6 0.0124
MTOR ENSG00000198793 2475 Membrane 6209.0 146000.0 1.56E-6 2.1E-4
PIK3C2B ENSG00000133056 5287 Membrane 731.0 601.0 1.55E-6 0.0145
PIK3R1 ENSG00000145675 5295 Membrane 31452.0 734000.0 1.56E-6 4.03E-5
PLD2 ENSG00000129219 5338 Membrane 723.0 98500.0 1.55E-6 0.00761
PLSCR1 ENSG00000188313 5359 Membrane 47.0 69.5 1.55E-6 0.139
RAB5A ENSG00000144566 5868 Membrane 237.0 34000.0 1.55E-6 0.0103
RAF1 ENSG00000132155 5894 Membrane 23706.0 140000.0 1.56E-6 1.64E-5
RALA ENSG00000006451 5898 Membrane 265.0 3420.0 1.55E-6 0.0137
RALBP1 ENSG00000017797 10928 Membrane 171.0 1720.0 1.55E-6 0.00826
RIN1 ENSG00000174791 9610 Membrane 60.0 14.6 1.55E-6 0.0475
EGFR ENSG00000146648 1956 Unknown 12590.0 758000.0 1.56E-6 2.83E-4
GRB2 ENSG00000177885 2885 Unknown 29079.0 822000.0 1.57E-6 5.64E-5
IQSEC1 ENSG00000144711 9922 Unknown 22.0 0.326 1.55E-6 0.0779
LIMK2 ENSG00000182541 3985 Unknown 266.0 1240.0 1.55E-6 0.00516
MAP3K2 ENSG00000169967 10746 Unknown 725.0 162.0 1.55E-6 0.00209
MAP3K7 ENSG00000135341 6885 Unknown 5836.0 93700.0 1.56E-6 2.59E-4
MAPK14 ENSG00000112062 1432 Unknown 9287.0 427000.0 1.56E-6 2.57E-4
PAK1 ENSG00000149269 5058 Unknown 5363.0 83300.0 1.56E-6 2.49E-4
PDPK1 ENSG00000140992 5170 Unknown 7752.0 22600.0 1.56E-6 2.91E-4
PLD1 ENSG00000075651 5337 Unknown 622.0 58700.0 1.55E-6 0.00792
PTK2 ENSG00000169398 5747 Unknown 9391.0 242000.0 1.56E-6 3.21E-4
PXDN ENSG00000130508 7837 Unknown 4.0 0.0 1.55E-6 1.0
REPS2 ENSG00000169891 9185 Unknown 29.0 21.4 1.55E-6 0.0911
SH3GL3 ENSG00000140600 6457 Unknown 98.0 301.0 1.55E-6 0.0396
STAT3 ENSG00000168610 6774 Unknown 10644.0 313000.0 1.56E-6 2.82E-4
ATF1 ENSG00000123268 466 Nucleus 146.0 409.0 1.55E-6 0.0251
AURKA ENSG00000087586 6790 Nucleus 684.0 67300.0 1.56E-6 0.0176
ELK4 ENSG00000158711 2005 Nucleus 277.0 134.0 1.55E-6 0.00181
JUND ENSG00000130522 3727 Nucleus 405.0 8110.0 1.56E-6 0.00956
MAP3K3 ENSG00000198909 4215 Nucleus 1237.0 3340.0 1.56E-6 0.00234
MYBL2 ENSG00000101057 4605 Nucleus 75.0 352.0 1.55E-6 0.0746
RPS6KA1 ENSG00000117676 6195 Nucleus 1675.0 7420.0 1.56E-6 6.33E-4
SP1 ENSG00000185591 6667 Nucleus 1577.0 413000.0 1.56E-6 0.00757
Symbol Ensembl ID Entrez ID Subcellular localization Degree Betweenness Closeness Transitivity
ABI1 ENSG00000136754 10006 Cytoplasm 36.0 8.18 2.13E-5 0.36031746
ARF6 ENSG00000165527 382 Cytoplasm 56.0 124.0 2.13E-5 0.127922078
ASAP1 ENSG00000153317 50807 Cytoplasm 21.0 6.12 2.1E-5 0.190476191
BRAF ENSG00000157764 673 Cytoplasm 520.0 6510.0 2.15E-5 0.003282941
CBLC ENSG00000142273 23624 Cytoplasm 38.0 19.5 2.12E-5 0.093883357
CSK ENSG00000103653 1445 Cytoplasm 104.0 197.0 2.14E-5 0.086631815
DNM1 ENSG00000106976 1759 Cytoplasm 21.0 335.0 2.12E-5 0.20952381
GAB1 ENSG00000109458 2549 Cytoplasm 710.0 2350.0 2.15E-5 0.006166193
GAB2 ENSG00000033327 9846 Cytoplasm 781.0 11700.0 2.15E-5 0.005331757
GRB10 ENSG00000106070 2887 Cytoplasm 75.0 13.4 2.13E-5 0.045765766
INPP5D ENSG00000168918 3635 Cytoplasm 251.0 136.0 2.13E-5 0.022693227
JAK1 ENSG00000162434 3716 Cytoplasm 1248.0 8450.0 2.15E-5 0.002257983
KRAS ENSG00000133703 3845 Cytoplasm 554.0 2070.0 2.15E-5 0.007102709
MAP4K1 ENSG00000104814 11184 Cytoplasm 84.0 216.0 2.13E-5 0.047619048
NEDD4 ENSG00000069869 4734 Cytoplasm 17.0 5.04 2.12E-5 0.257352941
PEBP1 ENSG00000089220 5037 Cytoplasm 30.0 1.85 2.12E-5 0.140229885
PLCE1 ENSG00000138193 51196 Cytoplasm 18.0 0.235 2.1E-5 0.156862745
PRKCD ENSG00000163932 5580 Cytoplasm 323.0 12200.0 2.16E-5 0.02263331
PTPN11 ENSG00000179295 5781 Cytoplasm 1537.0 16400.0 2.15E-5 0.001603672
PTPN5 ENSG00000110786 84867 Cytoplasm 7.0 6.7E-4 2.11E-5 0.238095238
RALB ENSG00000144118 5899 Cytoplasm 19.0 12.6 2.11E-5 0.128654971
RALGDS ENSG00000160271 5900 Cytoplasm 31.0 7.57 2.11E-5 0.049462366
SH2D2A ENSG00000027869 9047 Cytoplasm 53.0 2.95 2.13E-5 0.161103048
SOS1 ENSG00000115904 6654 Cytoplasm 1954.0 4650.0 2.15E-5 9.81615E-4
SOS2 ENSG00000100485 6655 Cytoplasm 117.0 803.0 2.14E-5 0.044503389
STMN1 ENSG00000117632 3925 Cytoplasm 43.0 299.0 2.13E-5 0.036544851
STXBP1 ENSG00000136854 6812 Cytoplasm 5.0 2.32 2.09E-5 0.5
TNK2 ENSG00000061938 10188 Cytoplasm 16.0 4.83 2.12E-5 0.325
USP6NL ENSG00000148429 9712 Cytoplasm 9.0 0.219 2.09E-5 0.138888889
CBL ENSG00000110395 867 Cytoplasm/Nucleus 724.0 3200.0 2.15E-5 0.005188632
CFL1 ENSG00000172757 1072 Cytoplasm/Nucleus 48.0 132.0 2.13E-5 0.057624114
CRK ENSG00000167193 1398 Cytoplasm/Nucleus 375.0 1900.0 2.15E-5 0.018039216
E2F1 ENSG00000101412 1869 Cytoplasm/Nucleus 575.0 28000.0 2.16E-5 0.007586729
EIF4EBP1 ENSG00000187840 1978 Cytoplasm/Nucleus 294.0 214.0 2.13E-5 0.001671658
ELK1 ENSG00000126767 2002 Cytoplasm/Nucleus 481.0 2810.0 2.15E-5 0.003005891
EPS8 ENSG00000151491 2059 Cytoplasm/Nucleus 28.0 16.2 2.12E-5 0.248677249
FOS ENSG00000170345 2353 Cytoplasm/Nucleus 346.0 5090.0 2.15E-5 0.007975203
FOXO4 ENSG00000184481 4303 Cytoplasm/Nucleus 102.0 1120.0 2.13E-5 0.0277616
JAK2 ENSG00000096968 3717 Cytoplasm/Nucleus 1156.0 5740.0 2.15E-5 0.002151021
JUN ENSG00000177606 3725 Cytoplasm/Nucleus 1533.0 157000.0 2.18E-5 0.002673984
MAP2K2 ENSG00000126934 5605 Cytoplasm/Nucleus 1788.0 2290.0 2.14E-5 3.47401E-4
MAP2K5 ENSG00000137764 5607 Cytoplasm/Nucleus 114.0 20.0 2.13E-5 0.018009626
MAPK1 ENSG00000100030 5594 Cytoplasm/Nucleus 3584.0 115000.0 2.18E-5 4.95738E-4
MAPK4 ENSG00000141639 5596 Cytoplasm/Nucleus 21.0 5.65 2.12E-5 0.090476191
MAPK7 ENSG00000166484 5598 Cytoplasm/Nucleus 124.0 202.0 2.14E-5 0.020456334
MAPK8 ENSG00000107643 5599 Cytoplasm/Nucleus 1392.0 35600.0 2.17E-5 0.001997653
MAPK9 ENSG00000050748 5601 Cytoplasm/Nucleus 700.0 3660.0 2.16E-5 0.002987942
MYC ENSG00000136997 4609 Cytoplasm/Nucleus 604.0 90500.0 2.17E-5 0.009110079
NCK2 ENSG00000071051 8440 Cytoplasm/Nucleus 28.0 3.49 2.12E-5 0.240740741
NCOA3 ENSG00000124151 8202 Cytoplasm/Nucleus 74.0 1540.0 2.15E-5 0.133654202
NEDD8 ENSG00000129559 4738 Cytoplasm/Nucleus 7.0 0.199 2.11E-5 0.666666667
PCNA ENSG00000132646 5111 Cytoplasm/Nucleus 65.0 403.0 2.13E-5 0.097115385
PIAS3 ENSG00000131788 10401 Cytoplasm/Nucleus 36.0 1.73 2.12E-5 0.053968254
PLCG1 ENSG00000124181 5335 Cytoplasm/Nucleus 752.0 6800.0 2.15E-5 0.005223532
PRKCA ENSG00000154229 5578 Cytoplasm/Nucleus 436.0 24600.0 2.15E-5 0.012474955
PTK2B ENSG00000120899 2185 Cytoplasm/Nucleus 294.0 927.0 2.14E-5 0.01602006
PTK6 ENSG00000101213 5753 Cytoplasm/Nucleus 17.0 0.00472 2.12E-5 0.191176471
PTPN12 ENSG00000127947 5782 Cytoplasm/Nucleus 16.0 1.53 2.11E-5 0.416666667
RPS6KA3 ENSG00000177189 6197 Cytoplasm/Nucleus 57.0 1120.0 2.14E-5 0.100877193
RPS6KA5 ENSG00000100784 9252 Cytoplasm/Nucleus 149.0 2360.0 2.14E-5 0.012787956
RPS6KB1 ENSG00000108443 6198 Cytoplasm/Nucleus 808.0 13200.0 2.16E-5 0.001852602
SH3GL2 ENSG00000107295 6456 Cytoplasm/Nucleus 24.0 13.9 2.11E-5 0.094202899
SH3KBP1 ENSG00000147010 30011 Cytoplasm/Nucleus 43.0 46.8 2.12E-5 0.147286822
SRC ENSG00000197122 6714 Cytoplasm/Nucleus 1835.0 67000.0 2.17E-5 0.001945688
STAT1 ENSG00000115415 6772 Cytoplasm/Nucleus 1494.0 36500.0 2.17E-5 0.002204845
STAT5A ENSG00000126561 6776 Cytoplasm/Nucleus 1017.0 56800.0 2.16E-5 0.003613763
STAT5B ENSG00000173757 6777 Cytoplasm/Nucleus 893.0 6570.0 2.15E-5 0.004022316
VAV2 ENSG00000160293 7410 Cytoplasm/Nucleus 316.0 1020.0 2.13E-5 0.017821981
AKT1 ENSG00000142208 207 Membrane 6565.0 233000.0 2.19E-5 2.13911E-4
ARHGEF1 ENSG00000076928 9138 Membrane 10.0 2.08 2.11E-5 0.244444444
DOK2 ENSG00000147443 9046 Membrane 32.0 1.6 2.12E-5 0.181451613
ERBB2 ENSG00000141736 2064 Membrane 471.0 3250.0 2.15E-5 0.010715092
HRAS ENSG00000174775 3265 Membrane 1733.0 25200.0 2.17E-5 0.001844377
ITCH ENSG00000078747 83737 Membrane 38.0 202.0 2.13E-5 0.081081081
MTOR ENSG00000198793 2475 Membrane 1113.0 11400.0 2.16E-5 0.001538392
PIK3C2B ENSG00000133056 5287 Membrane 37.0 5.22 2.13E-5 0.355855856
PIK3R1 ENSG00000145675 5295 Membrane 2347.0 18200.0 2.15E-5 6.63995E-4
PLD2 ENSG00000129219 5338 Membrane 38.0 82.3 2.12E-5 0.155049787
PLSCR1 ENSG00000188313 5359 Membrane 13.0 7.01 2.12E-5 0.448717949
RAB5A ENSG00000144566 5868 Membrane 17.0 86.6 2.12E-5 0.125
RAF1 ENSG00000132155 5894 Membrane 1624.0 13700.0 2.15E-5 6.27525E-4
RALA ENSG00000006451 5898 Membrane 38.0 128.0 2.12E-5 0.051209104
RALBP1 ENSG00000017797 10928 Membrane 31.0 1910.0 2.12E-5 0.021505376
RIN1 ENSG00000174791 9610 Membrane 12.0 2.1 2.11E-5 0.196969697
EGFR ENSG00000146648 1956 Unknown 1156.0 40200.0 2.17E-5 0.002804116
GRB2 ENSG00000177885 2885 Unknown 3192.0 57100.0 2.17E-5 5.90241E-4
IQSEC1 ENSG00000144711 9922 Unknown 5.0 0.17 2.11E-5 0.1
LIMK2 ENSG00000182541 3985 Unknown 38.0 369.0 2.11E-5 0.027027027
MAP3K2 ENSG00000169967 10746 Unknown 88.0 28.5 2.13E-5 0.037617555
MAP3K7 ENSG00000135341 6885 Unknown 710.0 23100.0 2.16E-5 0.003210235
MAPK14 ENSG00000112062 1432 Unknown 1219.0 74200.0 2.17E-5 0.002559367
PAK1 ENSG00000149269 5058 Unknown 708.0 9870.0 2.16E-5 0.00427125
PDPK1 ENSG00000140992 5170 Unknown 471.0 1780.0 2.15E-5 0.008348015
PLD1 ENSG00000075651 5337 Unknown 37.0 74.9 2.12E-5 0.13963964
PTK2 ENSG00000169398 5747 Unknown 920.0 14400.0 2.16E-5 0.003269149
PXDN ENSG00000130508 7837 Unknown 4.0 0.0 2.11E-5 1.0
REPS2 ENSG00000169891 9185 Unknown 10.0 20.0 2.11E-5 0.177777778
SH3GL3 ENSG00000140600 6457 Unknown 11.0 1.67 2.09E-5 0.181818182
STAT3 ENSG00000168610 6774 Unknown 1753.0 59100.0 2.17E-5 0.001825963
ATF1 ENSG00000123268 466 Nucleus 45.0 87.1 2.13E-5 0.070707071
AURKA ENSG00000087586 6790 Nucleus 65.0 4610.0 2.14E-5 0.060576923
ELK4 ENSG00000158711 2005 Nucleus 63.0 3310.0 2.12E-5 0.013824885
JUND ENSG00000130522 3727 Nucleus 78.0 4010.0 2.14E-5 0.027972028
MAP3K3 ENSG00000198909 4215 Nucleus 121.0 104.0 2.14E-5 0.043801653
MYBL2 ENSG00000101057 4605 Nucleus 10.0 3490.0 2.11E-5 0.088888889
RPS6KA1 ENSG00000117676 6195 Nucleus 239.0 219.0 2.14E-5 0.00762983
SP1 ENSG00000185591 6667 Nucleus 262.0 17100.0 2.16E-5 0.031294785
Gene1 Gene2 Weight KEGG humanCyc PID BioGRID IntAct HPRD BIND Reactome CORUM DIP WikiPathways ReconX INOH SMPDB PhosphoSite PANTHER CTD NetPath TRANSFAC DrugBank
ABI1 EPS8 5
ABI1 SOS1 4
AKT1 BRAF 4
AKT1 EGFR 4
AKT1 EIF4EBP1 4
AKT1 FOXO4 10
AKT1 MTOR 11
AKT1 PLCG1 4
AKT1 RAF1 6
AKT1 RPS6KB1 6
AKT1 SP1 1
AKT1 STAT1 3
AKT1 STAT3 2
ARF6 MAPK1 1
ARF6 PLD1 4
ARF6 PLD2 2
ASAP1 ARF6 2
ASAP1 PTK2 3
ATF1 JUN 3
AURKA AKT1 1
AURKA LIMK2 1
AURKA RALA 1
BRAF CRK 2
BRAF HRAS 7
BRAF MAP2K2 11
BRAF MAPK1 6
BRAF RAF1 9
BRAF STAT1 1
BRAF STAT3 1
BRAF STAT5A 1
BRAF STAT5B 1
CBLC EGFR 5
CBLC PIK3R1 1
CBL CRK 10
CBL EGFR 11
CBL ERBB2 3
CBL GRB2 10
CBL HRAS 2
CBL JAK1 2
CBL JAK2 2
CBL PIK3R1 9
CBL PLCG1 7
CBL PRKCA 5
CBL PTK2B 3
CBL PTPN11 4
CBL SH3GL2 5
CBL SH3GL3 3
CBL SH3KBP1 8
CBL SOS1 5
CBL SRC 6
CBL VAV2 4
CRK DOK2 3
CRK GAB1 5
CRK GAB2 2
CRK GRB2 5
CRK MAP3K7 1
CRK MAP4K1 6
CRK MAPK8 6
CRK PIK3R1 6
CRK PTK2 5
CRK PTK2B 3
CRK PTPN11 3
CRK SH3KBP1 3
CRK SOS1 5
CRK SRC 5
CSK AKT1 1
CSK MAP2K2 1
CSK MAPK1 1
CSK PTK2 3
CSK SRC 8
CSK STAT1 1
CSK STAT3 1
CSK STAT5A 1
CSK STAT5B 1
DNM1 EGFR 1
DNM1 SH3GL2 4
DOK2 GRB2 2
E2F1 MAP3K7 2
E2F1 MYC 3
E2F1 PCNA 3
E2F1 RPS6KA5 2
E2F1 SP1 5
EGFR EPS8 5
EGFR ERBB2 11
EGFR GAB1 8
EGFR GAB2 3
EGFR GRB2 12
EGFR HRAS 4
EGFR IQSEC1 2
EGFR JAK1 4
EGFR JAK2 3
EGFR KRAS 3
EGFR MAPK1 4
EGFR MTOR 2
EGFR NCK2 5
EGFR PCNA 2
EGFR PDPK1 3
EGFR PIK3C2B 6
EGFR PIK3R1 8
EGFR PLCG1 10
EGFR PLD2 5
EGFR PRKCA 5
EGFR PRKCD 3
EGFR PTK2 7
EGFR PTK6 5
EGFR PTPN11 7
EGFR RIN1 3
EGFR SH3GL2 5
EGFR SH3GL3 3
EGFR SH3KBP1 6
EGFR SOS1 9
EGFR SOS2 7
EGFR SRC 8
EGFR STAT1 7
EGFR STAT3 8
EGFR STAT5A 7
EGFR STAT5B 7
EGFR USP6NL 3
EGFR VAV2 7
ELK1 ELK4 3
ELK1 FOS 5
ELK4 FOS 3
EPS8 SOS1 4
EPS8 USP6NL 4
ERBB2 AKT1 2
ERBB2 GAB1 2
ERBB2 GAB2 3
ERBB2 GRB2 9
ERBB2 HRAS 5
ERBB2 JAK1 3
ERBB2 JAK2 4
ERBB2 MAPK1 2
ERBB2 MAPK8 1
ERBB2 PIK3C2B 4
ERBB2 PIK3R1 7
ERBB2 PLCG1 6
ERBB2 PTK2 5
ERBB2 PTK2B 4
ERBB2 PTK6 4
ERBB2 PTPN11 5
ERBB2 SOS1 4
ERBB2 SRC 5
ERBB2 STAT1 3
ERBB2 STAT3 3
ERBB2 VAV2 3
FOS JUN 12
FOS JUND 6
GAB1 AKT1 3
GAB1 GRB2 9
GAB1 INPP5D 3
GAB1 MAPK1 3
GAB1 MAPK8 1
GAB1 NCK2 3
GAB1 PIK3R1 8
GAB1 PLCG1 8
GAB1 PTPN11 9
GAB1 SOS1 6
GAB1 STAT3 3
GAB1 VAV2 3
GAB2 AKT1 3
GAB2 GAB1 3
GAB2 GRB2 7
GAB2 INPP5D 3
GAB2 JAK2 2
GAB2 MAPK1 4
GAB2 PDPK1 2
GAB2 PIK3R1 7
GAB2 PLCG1 3
GAB2 PTPN11 7
GAB2 SOS1 3
GAB2 SRC 4
GRB10 NEDD4 3
GRB2 AKT1 3
GRB2 HRAS 4
GRB2 INPP5D 5
GRB2 JAK1 5
GRB2 JAK2 5
GRB2 KRAS 3
GRB2 MAPK1 2
GRB2 MTOR 1
GRB2 PAK1 4
GRB2 PDPK1 3
GRB2 PIK3R1 9
GRB2 PLCG1 7
GRB2 PRKCD 2
GRB2 PTK2 8
GRB2 PTPN11 9
GRB2 SH3KBP1 5
GRB2 SOS1 12
GRB2 SOS2 7
GRB2 SRC 5
GRB2 STAT3 1
GRB2 VAV2 6
HRAS FOS 1
HRAS JUN 3
HRAS MAP2K2 2
HRAS MAPK1 3
HRAS PIK3R1 7
HRAS RAF1 14
HRAS RALA 2
HRAS RALGDS 11
HRAS RIN1 6
HRAS SOS1 7
INPP5D JAK1 4
INPP5D PRKCD 2
INPP5D PTPN11 4
INPP5D RAF1 1
IQSEC1 ARF6 2
ITCH SH3GL2 5
JAK1 AKT1 4
JAK1 DOK2 1
JAK1 GAB1 1
JAK1 JAK2 4
JAK1 MAPK1 2
JAK1 PDPK1 2
JAK1 PIK3R1 6
JAK1 PTK2B 4
JAK1 PTPN11 7
JAK1 SOS1 2
JAK1 STAT1 9
JAK1 STAT3 11
JAK1 STAT5A 8
JAK1 STAT5B 7
JAK2 AKT1 2
JAK2 ARHGEF1 1
JAK2 BRAF 1
JAK2 GAB1 1
JAK2 MAPK1 3
JAK2 PAK1 2
JAK2 PDPK1 1
JAK2 PIK3R1 8
JAK2 PLCG1 2
JAK2 PTK2 3
JAK2 PTK2B 3
JAK2 PTPN11 6
JAK2 RAF1 3
JAK2 SOS1 3
JAK2 SRC 4
JAK2 STAT1 11
JAK2 STAT3 11
JAK2 STAT5A 9
JAK2 STAT5B 8
JAK2 VAV2 1
JUND SP1 2
JUN JUND 4
JUN MYC 4
JUN SRC 2
JUN STAT1 3
KRAS BRAF 5
KRAS FOS 1
KRAS JUN 1
KRAS MAPK1 3
KRAS PIK3R1 3
KRAS RAF1 10
KRAS RALGDS 6
LIMK2 CFL1 5
MAP2K2 AKT1 1
MAP2K2 MAPK1 10
MAP2K2 MAPK14 1
MAP2K2 MAPK7 1
MAP2K2 MAPK8 4
MAP2K2 MAPK9 2
MAP2K2 RAF1 7
MAP2K2 STAT1 1
MAP2K2 STAT3 2
MAP2K2 STAT5A 1
MAP2K2 STAT5B 1
MAP2K5 AKT1 1
MAP2K5 MAP3K3 6
MAP2K5 MAPK14 1
MAP2K5 MAPK7 10
MAP2K5 MAPK8 1
MAP2K5 MAPK9 1
MAP2K5 STAT1 1
MAP2K5 STAT3 1
MAP2K5 STAT5A 1
MAP2K5 STAT5B 1
MAP3K2 AKT1 1
MAP3K2 MAP2K5 4
MAP3K2 MAPK8 3
MAP3K2 MAPK9 1
MAP3K2 SH2D2A 4
MAP3K2 STAT1 1
MAP3K2 STAT3 1
MAP3K2 STAT5A 1
MAP3K2 STAT5B 1
MAP3K3 AKT1 1
MAP3K3 MAP3K7 4
MAP3K3 MAPK14 1
MAP3K3 MAPK8 1
MAP3K3 MAPK9 1
MAP3K3 STAT1 1
MAP3K3 STAT3 1
MAP3K3 STAT5A 1
MAP3K3 STAT5B 1
MAP3K7 AKT1 1
MAP3K7 MAP2K2 1
MAP3K7 MAP2K5 1
MAP3K7 MAPK1 1
MAP3K7 MAPK14 4
MAP3K7 MAPK8 5
MAP3K7 MAPK9 2
MAP3K7 STAT1 1
MAP3K7 STAT3 7
MAP3K7 STAT5A 1
MAP3K7 STAT5B 1
MAPK14 ATF1 1
MAPK14 ELK1 5
MAPK14 ELK4 2
MAPK14 FOS 3
MAPK14 JUN 3
MAPK14 NCOA3 5
MAPK14 RPS6KA5 9
MAPK14 STAT1 5
MAPK14 STAT3 4
MAPK14 STAT5B 1
MAPK1 ABI1 2
MAPK1 AKT1 2
MAPK1 ELK1 9
MAPK1 ELK4 3
MAPK1 FOS 5
MAPK1 GRB10 1
MAPK1 JUND 3
MAPK1 MAPK7 1
MAPK1 MYC 5
MAPK1 PTPN12 1
MAPK1 PTPN5 3
MAPK1 RAF1 5
MAPK1 RPS6KA1 10
MAPK1 RPS6KA3 9
MAPK1 RPS6KA5 7
MAPK1 RPS6KB1 5
MAPK1 SOS1 5
MAPK1 SP1 3
MAPK1 SRC 3
MAPK1 STAT1 2
MAPK1 STAT3 6
MAPK1 STAT5A 6
MAPK1 STAT5B 3
MAPK7 AKT1 1
MAPK7 ELK1 1
MAPK7 ELK4 3
MAPK7 FOS 1
MAPK7 JUN 1
MAPK7 MYC 3
MAPK7 RPS6KA1 4
MAPK7 RPS6KA3 3
MAPK7 RPS6KA5 1
MAPK7 RPS6KB1 1
MAPK7 STAT1 2
MAPK7 STAT3 2
MAPK7 STAT5A 2
MAPK7 STAT5B 2
MAPK8 ELK1 3
MAPK8 FOS 4
MAPK8 FOXO4 2
MAPK8 ITCH 1
MAPK8 JUN 9
MAPK8 JUND 5
MAPK8 MAPK9 4
MAPK8 MYC 4
MAPK8 NCOA3 2
MAPK8 RPS6KA1 1
MAPK8 RPS6KA3 1
MAPK8 RPS6KA5 1
MAPK8 RPS6KB1 4
MAPK8 SP1 2
MAPK8 STAT1 2
MAPK8 STAT3 6
MAPK8 STAT5A 2
MAPK8 STAT5B 2
MAPK9 AKT1 1
MAPK9 FOS 4
MAPK9 FOXO4 2
MAPK9 ITCH 1
MAPK9 JUN 8
MAPK9 JUND 2
MAPK9 MYC 1
MAPK9 STAT1 2
MAPK9 STAT3 4
MAPK9 STAT5B 1
MTOR EIF4EBP1 8
MTOR GRB10 1
MTOR MYC 2
MTOR PDPK1 3
MTOR PRKCA 2
MTOR RPS6KB1 8
MTOR STAT1 3
MTOR STAT3 4
MTOR STAT5A 1
MTOR STAT5B 1
MYC PIAS3 1
MYC RPS6KA5 2
NCK2 MAPK14 1
NCK2 PAK1 8
NCK2 PTK2 3
NCK2 SOS1 4
NEDD4 TNK2 3
PAK1 AURKA 1
PAK1 BRAF 1
PAK1 CRK 1
PAK1 JUN 1
PAK1 LIMK2 1
PAK1 MAP2K2 1
PAK1 MAPK14 3
PAK1 MAPK4 1
PAK1 MAPK8 3
PAK1 MAPK9 1
PAK1 PLCG1 3
PAK1 RAF1 8
PAK1 STAT1 1
PAK1 STAT3 1
PAK1 STAT5A 1
PAK1 STAT5B 1
PAK1 STMN1 3
PAK1 VAV2 4
PDPK1 AKT1 8
PDPK1 MAP2K2 1
PDPK1 PAK1 1
PDPK1 PRKCA 1
PDPK1 PRKCD 4
PDPK1 RALGDS 2