Users can submit a gene list to extract a transcriptional regulatory subnetwork.
This subnetwork consists of the submitted genes and their one-step neighbors within TF-differentially expressed gene network.
TF-target relationships supported by the ChIP-seq data are represented by the thick lines in the subnetwork.
Users can choose the size of the subnetwork to display.
In the meanwhile, KnockTF provides topological features of the subnetwork genes, including degree, betweenness and closeness.