KnockTF-Search-Gene name

Gene Overview

Target Gene:	ASCL1
NCBI Official Symbol:	ASCL1
Entrez ID:	429
Ensembl ID:	ENSG00000139352
Gene Full Name:	achaete-scute family bHLH transcription factor 1
Strand:	+
Gene Locus:	12q23.2
External Links:

ASCL1 Significantly Regulated by These T(co)Fs

T(co)Fs that Activate ASCL1

T(co)Fs that Repress ASCL1

The Intensity of the Gene Regulated by T(co)Fs:

ASCL1-T(co)F Pairs

Showing 1 to 10 of 221 entries

Search:

Target Gene	T(co)F	Knock -Method	Tissue Type	Biosample Name	Fold Change	Log2FC	P-value	Corrected _P	Dataset ID
ASCL1	PTPN14	CRISPR	Brain	U5-NPC	0.0328853	-4.92641	2.30316e-04	2.30316e-04	DataSet_03_357
ASCL1	TFAP4	siRNA	Brain	BE(2)-C	0.10075	-3.3112	1.52460e-01	1.52460e-01	DataSet_01_295
ASCL1	ESR1	siRNA	Mammary_gland	MCF7	0.132585	-2.91501	4.11139e-04	4.11139e-04	DataSet_03_352
ASCL1	YBX1	CRISPR	Haematopoietic_and_lymphoid_tissue	K562	0.148148	-2.75489	1.99597e-01	1.99597e-01	DataSet_04_022
ASCL1	PTBP1	shRNA	Haematopoietic_and_lymphoid_tissue	K562	0.16	-2.64386	3.10000e-04	3.10000e-04	DataSet_02_131
ASCL1	FOXA1	siRNA	Mammary_gland	MCF7	0.192022	-2.38066	4.57636e-15	4.57636e-15	DataSet_03_081
ASCL1	FOXA1	siRNA	Mammary_gland	MCF7	0.192022	-2.38066	4.57636e-15	4.57636e-15	DataSet_03_082
ASCL1	AGO2	shRNA	Haematopoietic_and_lymphoid_tissue	K562	0.2	-2.32193	2.82800e-02	2.82800e-02	DataSet_02_132
ASCL1	CDC5L	CRISPR	Haematopoietic_and_lymphoid_tissue	K562	0.2	-2.32193	5.67471e-02	5.67471e-02	DataSet_04_002
ASCL1	CDC5L	CRISPR	Haematopoietic_and_lymphoid_tissue	K562	0.2	-2.32193	7.37230e-02	7.37230e-02	DataSet_04_074

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Regulation Region

T(co)F Identified by ChIP-seq T(co)F Predicted by Motif

T(co)Fs that significantly regulate FOXA1 by the evidences of both expression and ChIP-seq/motif

Expression Atlas of ASCL1

Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)

Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines