Gene Overview
Target Gene: BAX
NCBI Official Symbol: BAX
Entrez ID: 581
Ensembl ID: ENSG00000087088
Gene Full Name: BCL2 associated X, apoptosis regulator
Strand: +
Gene Locus: 19q13.33
External Links:

BAX Significantly Regulated by These T(co)Fs

T(co)Fs that Activate BAX   
T(co)Fs that Repress BAX
The Intensity of the Gene Regulated by T(co)Fs:
BAX-T(co)F Pairs
Target
Gene		 T(co)F Knock
-Method		 Tissue Type Biosample
Name		 Fold
Change		 Log2FC P-value Corrected
_P		 Dataset ID
BAX MYB shRNA Fetal_liver Primary CD34+ hematopoietic stem/progenitor cells (HSPCs) 0.59967 -0.73777 8.42531e-07 1.17376e-05 DataSet_01_102
BAX SPDEF shRNA Mammary_gland MCF7 0.64149 -0.64051 0.79166 0.99999 DataSet_01_107
BAX HOXA1 siRNA Lung_fibroblast IMR-90 1.64214 0.71558 0.05372 0.2484 DataSet_01_110
BAX GABPA siRNA Lung A549 0.46078 -1.11786 7.7564e-07 8.98865e-06 DataSet_01_113
BAX ZIC2 siRNA Pancreas PANC1 2.37933 1.25056 - - DataSet_01_121
BAX FOXM1 siRNA Central_nervous_system U87 0.49969 -1.00088 - - DataSet_01_122
BAX ID1 shRNA Neuroepithelium GSC8 1.61456 0.69114 2.09593e-08 5.54968e-08 DataSet_01_134
BAX TFAP2C shRNA Mammary_gland MCF7 0.57787 -0.79118 4.62649e-06 2.22571e-05 DataSet_01_150
BAX HSF1 shRNA Skin A375 1.52388 0.60775 0.05852 0.21372 DataSet_01_155
BAX ELK1 siRNA Peripheral_blood CD4+ T cells 0.23922 -2.06358 0.70871 0.85261 DataSet_01_162
BAX GATA3 siRNA Peripheral_blood CD4+ T cells 0.12316 -3.02136 0.62422 0.83057 DataSet_01_163
BAX JUN siRNA Peripheral_blood CD4+ T cells 65.8715 6.04158 0.17477 0.40704 DataSet_01_164
BAX MAF siRNA Peripheral_blood CD4+ T cells 0.16603 -2.59052 0.92029 0.96911 DataSet_01_165
BAX NFATC3 siRNA Peripheral_blood CD4+ T cells 0.22924 -2.12507 0.77788 0.9055 DataSet_01_166
BAX NFKB1 siRNA Peripheral_blood CD4+ T cells 0.1273 -2.97372 0.64996 0.86208 DataSet_01_167
BAX STAT3 siRNA Peripheral_blood CD4+ T cells 0.12452 -3.00556 0.63459 0.99183 DataSet_01_168
BAX TP53 siRNA Lung SAECs 0.63842 -0.64743 0.00898 0.25168 DataSet_01_175
BAX GABPA shRNA Prostate C4-2B 2316.68 11.1778 0.23564 0.43934 DataSet_01_190
BAX GABPA shRNA Prostate LNCaP 1414.96 10.4665 0.46122 0.7048 DataSet_01_191
BAX GATA2 siRNA Prostate LNCaP 0.46553 -1.10305 0.00046 0.00325 DataSet_01_193
BAX LIN28A siRNA Embryo H9 1.65064 0.72302 0.0159 0.06557 DataSet_01_215
BAX SMAD2 siRNA Liver Hep3B 1.71417 0.77751 - - DataSet_01_248
BAX SMAD4 siRNA Liver Hep3B 2.01947 1.01398 - - DataSet_01_250
BAX FOXO3 siRNA Pancreas PANC1 0.64094 -0.64175 - - DataSet_01_267
BAX AR shRNA Prostate CWR22Pc 1.69183 0.75858 0.00878 0.05611 DataSet_01_278
BAX TFAP4 siRNA Brain BE(2)-C 0.19492 -2.35908 0.33331 0.51625 DataSet_01_295
BAX ERG siRNA Cervix HeLa 1.67041 0.7402 7.90671e-12 1.82731e-10 DataSet_01_316
BAX ELK3 shRNA Mammary_gland MDA-MB-231 1.6848 0.75258 0.00012 0.00066 DataSet_01_318
BAX HNRNPUL1 shRNA Liver HepG2 2.00869 1.00625 0.00081 0.01982 DataSet_02_109
BAX BCLAF1 shRNA Liver HepG2 0.46202 -1.11398 0.01495 0.06029 DataSet_02_112
BAX U2AF2 shRNA Liver HepG2 0.51614 -0.95418 0.69088 0.78677 DataSet_02_113
BAX TARDBP shRNA Liver HepG2 0.61672 -0.69731 0.01199 0.0411 DataSet_02_116
BAX SUB1 shRNA Liver HepG2 0.66066 -0.59801 0.07121 0.23075 DataSet_02_117
BAX RBM25 shRNA Liver HepG2 0.65548 -0.60937 0.0034 0.02605 DataSet_02_119
BAX HNRNPLL shRNA Liver HepG2 0.656 -0.60824 0.00456 0.02217 DataSet_02_125
BAX SNRNP70 shRNA Liver HepG2 0.60295 -0.7299 0.005 0.0403 DataSet_02_126
BAX SRSF3 shRNA Liver HepG2 0.61099 -0.71077 0.03257 0.12797 DataSet_02_127
BAX TARDBP shRNA Haematopoietic_and_lymphoid_tissue K562 1.8809 0.91143 0.41895 0.68537 DataSet_02_129
BAX PTBP1 shRNA Haematopoietic_and_lymphoid_tissue K562 1.93525 0.95252 0.05288 0.11699 DataSet_02_131
BAX TAF15 shRNA Haematopoietic_and_lymphoid_tissue K562 0.46933 -1.09131 0.79095 0.89538 DataSet_02_140
BAX DROSHA shRNA Haematopoietic_and_lymphoid_tissue K562 0.64529 -0.63198 0.18637 0.5462 DataSet_02_145
BAX RBM39 shRNA Haematopoietic_and_lymphoid_tissue K562 0.49079 -1.02682 0.06098 0.2635 DataSet_02_151
BAX FUS shRNA Haematopoietic_and_lymphoid_tissue K562 0.62348 -0.68158 0.06425 0.28181 DataSet_02_155
BAX HNRNPUL1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.51531 -0.95648 0.09988 0.51652 DataSet_02_156
BAX U2AF1 shRNA Haematopoietic_and_lymphoid_tissue K562 0.55572 -0.84757 0.01175 0.14086 DataSet_02_165
BAX RBM22 shRNA Haematopoietic_and_lymphoid_tissue K562 1.71658 0.77954 0.11355 0.22282 DataSet_02_168
BAX U2AF2 shRNA Haematopoietic_and_lymphoid_tissue K562 0.54151 -0.88494 0.00107 0.04371 DataSet_02_170
BAX CEBPZ siRNA Haematopoietic_and_lymphoid_tissue K562 0.51363 -0.9612 0.16516 1 DataSet_02_176
BAX ATF3 siRNA Haematopoietic_and_lymphoid_tissue K562 1.59878 0.67697 0.17599 1 DataSet_02_180
BAX BRCA1 siRNA Haematopoietic_and_lymphoid_tissue K562 0.62908 -0.66869 0.28564 1 DataSet_02_202
BAX AR siRNA Prostate LNCaP 0.574043 -0.800769 0.105652027917129 1 DataSet_03_005
BAX AR siRNA Mammary_gland MCF7 1.9949 0.996317 5.00148717531886e-07 0.00010131736041747 DataSet_03_006
BAX BCL6 siRNA Mammary_gland MCF7 0.636497 -0.651773 0.34814593514535 0.989541443114508 DataSet_03_024
BAX BRCA1 siRNA Mammary_gland MCF7 1.70485 0.769649 0.27427649751161 0.999850583334387 DataSet_03_028
BAX BRCA2 siRNA Mammary_gland MCF7 0.577874 -0.791172 0.262316847129438 0.999441861952364 DataSet_03_029
BAX CCNA2 siRNA Mammary_gland MCF7 0.601177 -0.734139 0.295016578937858 0.881144737092661 DataSet_03_034
BAX CEBPA siRNA Mammary_gland MCF7 0.572402 -0.804898 0.254925613488419 0.999962793175751 DataSet_03_047
BAX CEBPB siRNA Embryo hESC 2.01549 1.01113 0.00321783756651744 0.165554808341461 DataSet_03_049
BAX CEBPD siRNA Mammary_gland MCF7 0.439349 -1.18656 0.111530982247569 0.999848455332859 DataSet_03_050
BAX CENPF siRNA Mammary_gland MCF7 0.448387 -1.15718 0.11902237933969 0.999662524742916 DataSet_03_052
BAX CHEK1 siRNA Mammary_gland MCF7 0.534346 -0.904154 0.206687303204826 0.999587656258211 DataSet_03_053
BAX CREBBP siRNA Mammary_gland MCF7 0.460542 -1.1186 0.12960863642665 0.966335354083345 DataSet_03_055
BAX CTNNB1 siRNA Mammary_gland MCF7 0.514006 -0.960143 0.183246646868184 0.999436862066063 DataSet_03_058
BAX E2F1 siRNA Mammary_gland MCF7 0.48474 -1.04472 0.152451429639093 0.999927373439084 DataSet_03_061
BAX E2F5 siRNA Mammary_gland MCF7 0.574778 -0.798924 0.258120223262946 0.999540347732068 DataSet_03_062
BAX ERF siRNA Mammary_gland MCF7 0.437581 -1.19238 0.110102934241353 0.999855523449227 DataSet_03_067
BAX ESRRA siRNA Mammary_gland MCF7 1.67744 0.74626 0.287794238023992 0.999964003642835 DataSet_03_072
BAX FOXF2 siRNA Mammary_gland MDA-MB-231 1.61483 0.691381 - - DataSet_03_087
BAX GATA3 siRNA Mammary_gland MCF7 0.5975 -0.742989 0.289728341203001 0.999831535534034 DataSet_03_102
BAX HDAC5 siRNA Mammary_gland MCF7 0.474666 -1.07502 0.142653788395811 0.999966625300244 DataSet_03_115
BAX HIC1 CRISPR Prostate PC3 0.599449 -0.738291 - - DataSet_03_118
BAX HSF2 siRNA Mammary_gland MCF7 0.419337 -1.25382 0.0960760528535732 0.990969613280381 DataSet_03_130
BAX JUN siRNA Mammary_gland MCF7 0.510088 -0.971181 0.443131094428804 0.999857657786768 DataSet_03_142
BAX KDM3A siRNA Mammary_gland MCF7 1.85131 0.888543 0.00258922649293552 0.0363245547698766 DataSet_03_146
BAX MAX siRNA Mammary_gland MCF7 0.60216 -0.731782 0.296438866134818 0.999907009675999 DataSet_03_158
BAX MCM2 siRNA Mammary_gland MCF7 0.513788 -0.960756 0.18300416656807 0.999925560383539 DataSet_03_161
BAX MYCN CRISPR Neuroblastoma CHP-134 1.69312 0.759687 0.000318269620379577 0.00486890291930226 DataSet_03_183
BAX MYCN CRISPR Neuroblastoma CHP-134 1.69312 0.759687 0.000318269620379577 0.00486890291930226 DataSet_03_184
BAX PCNA siRNA Mammary_gland MCF7 0.336081 -1.57312 0.0473965124472492 0.999448838103647 DataSet_03_210
BAX POLR2A siRNA Mammary_gland MCF7 0.46701 -1.09847 0.0566000680850834 0.999513313282531 DataSet_03_213
BAX RB1 siRNA Mammary_gland MCF7 0.383282 -1.38352 0.0720360532569674 0.999890290262508 DataSet_03_219
BAX RELB siRNA Immortalized_keratinocyte HaCaT 1.94414 0.959135 3.74975498164152e-05 0.00055543245665565 DataSet_03_227
BAX SMAD7 siRNA Mammary_gland MCF7 0.62652 -0.674567 0.332724963820213 0.99858912864726 DataSet_03_234
BAX SOX11 siRNA Lung_fibroblast NHLF 1.68205 0.750223 0.0198645945616494 0.236419425395272 DataSet_03_238
BAX SRF siRNA Prostate LNCaP 2.413 1.27083 0.000128453446911679 0.00205709219130291 DataSet_03_254
BAX STAT3 CRISPR Embryo hESC 0.617985 -0.694356 0.0280541957497032 0.0958070603357995 DataSet_03_258
BAX STAT5B siRNA Mammary_gland MCF7 0.344866 -1.53589 0.0514360439695051 0.999932708473107 DataSet_03_263
BAX TCEA1 siRNA Mammary_gland MCF7 0.642025 -0.639299 0.356821468215973 0.999762252994287 DataSet_03_266
BAX TFE3 siRNA Kidney UOK257-2 1.75507 0.811531 - - DataSet_03_275
BAX TP53 siRNA Mammary_gland MCF7 0.332991 -1.58644 0.046031755927182 0.999938217444253 DataSet_03_277
BAX TP53 knockout Haematopoietic_and_lymphoid_tissue MM1S 0.504154 -0.988064 0.0243205014048196 0.994828053448528 DataSet_03_279
BAX TP53 knockout Haematopoietic_and_lymphoid_tissue MOLP8 0.60713 -0.719924 0.0381943695382559 0.680998851946907 DataSet_03_280
BAX TP63 siRNA Skin Primary neonatal keratinocytes 2.19568 1.13467 4.46758000214989e-05 0.00208054720315174 DataSet_03_281
BAX WT1 siRNA Mammary_gland MCF7 0.394656 -1.34133 0.0791068855812404 0.999957852801679 DataSet_03_285
BAX ZNF750 siRNA Skin Primary neonatal keratinocytes 1.99198 0.994206 0.0046221657096438 0.0556946272765112 DataSet_03_294
BAX CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 1.71828 0.78097 0.00288623918590526 0.0469646267288304 DataSet_04_002
BAX CIZ1 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.568039 -0.815938 0.00168686646669765 0.02131287900292 DataSet_04_004
BAX NKRF shRNA Haematopoietic_and_lymphoid_tissue K562 0.094734 -3.39997 0.0137921926095852 0.0606413299277484 DataSet_04_014
BAX RIOK2 CRISPR Liver HepG2 1.71326 0.776748 0.145124637405778 0.950962289708616 DataSet_04_070
BAX CNOT7 shRNA Liver HepG2 3.00072 1.58531 8.78806031961058e-05 0.00259616664004982 DataSet_04_051
BAX SMG7 CRISPR Haematopoietic_and_lymphoid_tissue K562 0.661546 -0.596086 0.00338260775964282 0.36988468995597 DataSet_04_075
BAX SNW1 CRISPR Haematopoietic_and_lymphoid_tissue K562 1.88582 0.915189 0.00157514082707821 0.0182684422993769 DataSet_04_049
BAX DPF2 CRISPRi Haematopoietic_and_lymphoid_tissue K562 0.64534 -0.631868 0.0149386385313617 0.049509474321844 DataSet_02_14
BAX CNOT3 shRNA Lung A549 1.61447 0.691058 1.812827e-01 0.8830540 DataSet_03_340
BAX SMARCA4 siRNA Colon HCT116 1.62587 0.701216 1.634644e-01 9.892536e-01 DataSet_03_301
BAX SMARCA4 siRNA Colon HCT116 2.09336 1.06582 3.382067e-03 0.1301247 DataSet_03_302
BAX CREBBP CRISPR Brain U5-NPC 2.67421 1.41911 0.2736324944 0.7490853 DataSet_03_356
BAX PTPN14 CRISPR Brain U5-NPC 0.480127 -1.05851 5.912808e-02 0.28332945 DataSet_03_357
BAX ARID2 shRNA Haematopoietic_and_lymphoid_tissue MM.1S 1.79576 0.844598 3.300936e-06 6.215582e-05 DataSet_03_362
BAX TP53 knockout Stomach SNU1 0.210931 -2.24516 0.0657281772 0.9301241 DataSet_03_365
BAX ZFP36L1 siRNA Urinary_bladder J82 1.89817 0.924612 - - DataSet_03_371
BAX ILF2 siRNA Stomach SGC-7901 1.51371 0.59809 0.0936984793 0.24390317 DataSet_03_393
BAX EHF shRNA Stomach MKN7 0.157789 -2.66394 - - DataSet_03_402
BAX CDK7 shRNA Bone_marrow D458 1.66763 0.737797 1.026752e-01 0.40284372 DataSet_03_404
BAX STRAP knockout Nerve SK-N-AS 0.584141 -0.775612 - - DataSet_03_409
BAX USP22 shRNA Liver HuH7 0.547007 -0.87037 - - DataSet_03_411
BAX ZKSCAN3 CRISPR Colon HCT116 1.73431 0.794361 6.097676e-03 0.184792910 DataSet_03_415
BAX USP7 shRNA Skin xenograft cells 0.414892 -1.26919 0.26592392 0.4348960 DataSet_03_431
BAX SETDB1 shRNA Colon HCT116 1.67443 0.743666 - - DataSet_03_440
BAX CAMTA1 knockout Embryo_kidney HEK293T 0.625455 -0.677022 4.926926e-03 0.09238218 DataSet_03_448
BAX IRF2 shRNA Cord_Blood CD34+ cells 1.59259 0.671377 - - DataSet_03_460
BAX TXNIP shRNA Cord_Blood CD34+ cells 1.59677 0.67516 - - DataSet_03_461
BAX TXNIP shRNA Cord_blood ST3 2.23684 1.16146 1.531166e-02 0.1841543325 DataSet_03_462
BAX SMARCA1 CRISPR-Csm Embryo_kidney HEK293T 2.2586 1.17543 - - DataSet_03_467
BAX EZH2 siRNA Prostate LNCaP 0.595201 -0.748552 - - DataSet_03_472
BAX CDC5L CRISPR Haematopoietic_and_lymphoid_tissue K562 1.71829 0.78097 0.0005218548 0.012181323 DataSet_04_074
Regulation Region
 
T(co)Fs that significantly regulate MCM2 by the evidences of both expression and ChIP-seq/motif
Expression Atlas of BAX
Gene Expression in Human Normal Tissues (GTEx) Gene Expression in Cancer Cell Lines (CCLE)
Gene Expression in Human Cancers (TCGA) Gene Expression in Encode Cell Lines